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List of works by Jo Knight

1990-2000: progress in determining high blood pressure genes.

scientific article

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.

scientific article

A Domain Based Approach to Semantic Lexicon Expansion ⬇️

A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays

scientific article

A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy.

scientific article published in January 2006

A comparison of association statistics between pooled and individual genotypes

scientific article

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

scientific article

A genome-wide association study of suicide severity scores in bipolar disorder.

scientific article published on 20 November 2014

A genome-wide significant linkage for severe depression on chromosome 3: the depression network study

scientific article

A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees

article

A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies

scientific article

A simple method for assessing the strength of evidence for association at the level of the whole gene

scientific article

A survey of current software for genetic power calculations

scientific article

APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

scientific article published on 01 October 2019

APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies

scholarly article by Usman Saeed et al published September 2018 in Alzheimer's and Dementia

Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models.

scientific article published on 30 September 2014

Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

article

Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS.

scientific article published on 13 April 2016

An investigation of candidate regions for association with bipolar disorder

scientific article published in October 2010

Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans

scientific article published on 01 October 2021

Application of multi-locus analytical methods to identify interacting loci in case-control studies

scientific article published on 10 April 2007

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

scientific article published on 22 May 2015

Association of the serotonin transporter gene, neuroticism and smoking behaviours

scientific article

CEREBRAL PERFUSION AS AN IMAGING BIOMARKER OF PRESYMPTOMATIC GENETIC FRONTOTEMPORAL DEMENTIA: PRELIMINARY RESULTS FROM THE GENETIC FRONTOTEMPORAL DEMENTIA INITIATIVE (GENFI)

CLUMPHAP: a simple tool for performing haplotype-based association analysis

scientific article published in September 2008

CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers--findings from two independent populations

scientific article

Can we accurately classify schizophrenia patients from healthy controls using magnetic resonance imaging and machine learning? A multi-method and multi-dataset study

scientific article published on 20 December 2017

Comment: Unraveling DNA sequence to identify cerebral indicators of dementia risk

scientific article published on 27 December 2017

Common variants in DGKK are strongly associated with risk of hypospadias

scientific journal article

Complex host genetics influence the microbiome in inflammatory bowel disease

scientific article

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

scientific article

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk ⬇️

scientific article published on 01 October 2019

DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association

scientific article

DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters.

scientific article published in November 2005

DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage

scientific article published in December 2008

Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder.

scientific article published on 30 January 2009

Design and Analysis of Association Studies using Pooled DNA from Large Twin Samples

scientific article published on 01 September 2006

Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic twins

scientific article published in June 2008

Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study

scientific article published on 13 May 2016

Dopamine genes and pathological gambling in discordant sib-pairs

scientific article

Endothelial nitric oxide gene haplotypes and risk of cerebral small-vessel disease

scientific article published on 12 February 2004

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

scientific article published on 5 May 2015

Erratum: The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

article

Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene

scientific article

Examining the role of common and rare mitochondrial variants in schizophrenia

scientific article published on 25 January 2018

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach

scientific article

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic association analysis of N-methyl-D-aspartate receptor subunit gene GRIN2B and clinical response to clozapine

scientific article published on 15 February 2016

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

scientific article published on 05 December 2018

Genetic epistasis regulates amyloid deposition in resilient aging

scientific article

Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases

scientific article published on 30 May 2016

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.

scientific article

Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences

scientific article

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

scientific article

Genome-wide mapping of human loci for essential hypertension

scientific article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

scientific article

Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD.

scientific article published in August 2004

Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy

article

Haplotype association analysis of discrete and continuous traits using mixture of regression models.

scientific article published in March 2004

Heritability estimates of cortical anatomy: The influence and reliability of different estimation strategies

article

Heritability of hippocampal subfield volumes using a twin and non-twin siblings design

scientific article published on 31 May 2017

Homing in on Depression Genes

scientific article published on 01 February 2007

Homing in on Depression Genes

Human chromosome 17 in essential hypertension

scientific article

IBD Genetic Risk Profile in Healthy First-Degree Relatives of Crohn's Disease Patients

scientific article published on 28 October 2015

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

scientific article

Identifying variation in GP referral rates: an observational study of outpatient headache referrals

scientific article published on 8 February 2022

Introduction to Genetic Association Studies ⬇️

scientific article published on March 1, 2012

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

scientific article

Investigation into the ability of SNP chipsets and microsatellites to detect association with a disease locus

scientific article published on 18 March 2008

Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes

scientific article published on January 2015

Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

scientific article published in June 2000

Investigation of the Ability of Haplotype Association and Logistic Regression to Identify Associated Susceptibility Loci

scientific article published on 01 November 2006

Late-onset epilepsy predicts stroke: Systematic review and meta-analysis

scientific article published on 14 December 2020

Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait

scientific article

Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.

scientific article

NADPH oxidase (CYBA) and FcγR polymorphisms as risk factors for aggressive periodontitis: A case–control association study

scientific article published on 01 August 2006

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Numbers and types of neurological emergencies in England and the influence of socioeconomic deprivation: a retrospective analysis of hospital episode statistics data

scientific article published on 4 November 2022

Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine

scientific article

Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease

scientific article published on 29 March 2006

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

scientific article

Predictors of Outcome in Ulcerative Colitis

scientific article

Program Report: GENECOUNTING Support Programs

scientific article published on 01 March 2006

Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain.

scientific article published on 16 April 2014

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B.

scientific article published in February 2005

Routinely collected patient data in neurology research: a systematic mapping review

scientific article published on 27 November 2020

SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children

scientific article published on 30 March 2005

Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants.

scientific article

Software for generating liability distributions for pedigrees conditional on their observed disease states and covariates

scientific article published on 01 February 2010

Study of regions of extended homozygosity provides a powerful method to explore haplotype structure of human populations.

scientific article published on 20 January 2008

TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease

scientific article published on 17 November 2004

The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder

scientific article published in October 2010

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

scientific article

The effect of haplotype-block definitions on inference of haplotype-block structure and htSNPs selection.

scientific article published on 15 September 2004

The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa

scientific article

Using Functional Annotation for the Empirical Determination of Bayes Factors for Genome-Wide Association Study Analysis ⬇️

scientific article (publication date: 27 April 2011)

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

scientific article

Variation in waiting times by diagnostic category: an observational study of 1,951 referrals to a neurology outpatient clinic

scientific article published in June 2021

Variation in waiting times by diagnostic category: an observational study of 1951 referrals to a neurology outpatient clinic

scientific article published on 13 January 2021

Whole genome linkage scan of recurrent depressive disorder from the depression network study

scientific article published on 3 October 2005

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