List of works - Morgan R. Alexander

3D ToF-SIMS imaging of polymer multilayer films using argon cluster sputter depth profiling.

scientific article published on 20 January 2015

3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling

scientific article published on 7 June 2015

3D extrusion printing of high drug loading immediate release paracetamol tablets.

scientific article published on 15 January 2018

3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release

scientific article

3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles

scientific article published on 18 September 2015

3D printing of tablets containing multiple drugs with defined release profiles.

scientific article published on 30 July 2015

3D printing of tablets using inkjet with UV photoinitiation.

scientific article published on 30 June 2017

A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays.

scientific article published on 15 May 2015

Ambient DESI and LESA-MS analysis of proteins adsorbed to a biomaterial surface using in-situ surface tryptic digestion.

scientific article published on 19 September 2013

Analysis and prediction of defects in UV photo-initiated polymer microarrays

scientific article published on 20 December 2012

Analytical techniques: surface and interfacial characterisation ⬇️

scientific article published on August 29, 2011

Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers

scientific article published on 26 July 2016

Attachment of stem cells to scaffold particles for intra-cerebral transplantation

scientific article published on 17 September 2009

Authentication of processed meat products by peptidomic analysis using rapid ambient mass spectrometry.

scientific article

Bacterial attachment to polymeric materials correlates with molecular flexibility and hydrophilicity

scientific article

Bioprinting Using Mechanically Robust Core-Shell Cell-Laden Hydrogel Strands.

scientific article published on 3 February 2017

Cell spreading correlates with calculated logP of amino acid-modified surfaces

scientific article published on 19 April 2007

Characterisation of a micro-plasma for ambient mass spectrometry imaging.

scientific article

Chemical and spatial analysis of protein loaded PLGA microspheres for drug delivery applications

article

Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4bm00054dClick here for [...]

scientific article

Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior.

scientific article published on 9 December 2015

Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells

scientific article published on 22 August 2010

Combinatorial discovery of polymers resistant to bacterial attachment

scientific article published on September 2012

Conditional gene expression in human embryonic stem cells

scientific article published on 22 February 2007

Controlling protein retention on enzyme-responsive surfaces

scientific article published on November 2006

Correction to Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study.

scientific article published on 15 October 2015

Desktop 3D printing of controlled release pharmaceutical bilayer tablets

scientific article published on 23 November 2013

Detection of negative molecular ions in acrylic acid plasma: some implications for polymerization mechanisms

scientific article published on 06 July 2007

Development and characterization of a stable adhesive bond between a poly(dimethylsiloxane) catheter material and a bacterial biofilm resistant acrylate polymer coating

scientific article published on 23 May 2017

Development and validation of a fluorescence method to follow the build-up of short peptide sequences on solid 2D surfaces

scientific article published on 05 January 2012

Dimerization of Tri(4-bromophenyl)benzene by Aryl−Aryl Coupling from Solution on a Gold Surface

scientific article published on 03 March 2011

Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration

scientific article published on 05 June 2020

Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation

scientific article published on June 2015

Discovery of a Novel Polymer for Xeno-Free, Long-Term Culture of Human Pluripotent Stem Cell Expansion

scientific article published on 28 December 2020

Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays

scientific article published on 18 February 2013

Dynamics of anterior-posterior axis formation in the developing mouse embryo

scientific article

Effect of sessile drop volume on the wetting anisotropy observed on grooved surfaces.

scientific article published in March 2009

Effects of Polymer 3D Architecture, Size, and Chemistry on Biological Transport and Drug Delivery In Vitro and in Orthotopic Triple Negative Breast Cancer Models

scientific article published on 19 October 2020

Enzyme-activated RGD ligands on functionalized poly(ethylene glycol) monolayers: surface analysis and cellular response.

scientific article published in July 2009

Extrusion 3D Printing of Paracetamol Tablets from a Single Formulation with Tunable Release Profiles Through Control of Tablet Geometry

scientific article published on 10 August 2018

Friction Force Microscopy of Alkylphosphonic Acid and Carboxylic Acids Adsorbed on the Native Oxide of Aluminum

scientific article published in October 2006

Fumed silica nanoparticle mediated biomimicry for optimal cell-material interactions for artificial organ development

scientific article published on 18 November 2013

High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry

scientific article

High throughput methods applied in biomaterial development and discovery

scientific article published on 07 October 2009

High throughput screening for biomaterials discovery

scientific article published on 30 June 2014

High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays.

scientific article

High-energy electron beam lithography of octadecylphosphonic acid monolayers on aluminum

scientific article published on 24 January 2008

Hippocampal cell response to substrates with surface chemistry gradients

scientific article published on 30 July 2011

Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion.

scientific article published on 28 July 2016

Image based Machine Learning for identification of macrophage subsets

scientific article

Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials

scientific article published on 11 March 2016

Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation

scientific article published on 28 April 2020

Impact of surface chemistry and topography on the function of antigen presenting cells.

scientific article published on 09 January 2015

Improved Extraction Repeatability and Spectral Reproducibility for Liquid Extraction Surface Analysis–Mass Spectrometry Using Superhydrophobic–Superhydrophilic Patterning

scientific article published on 03 May 2018

Influence of the plasma sheath on plasma polymer deposition in advance of a mask and down pores.

scientific article published in June 2009

Inkjet printing as a novel medicine formulation technique

scientific article published on 29 July 2011

Intracellular Drug Uptake-A Comparison of Single Cell Measurements Using ToF-SIMS Imaging and Quantification from Cell Populations with LC/MS/MS.

scientific article published on 17 October 2017

Investigation of cell-surface interactions using chemical gradients formed from plasma polymers.

scientific article published on 18 October 2007

Lipids and polymers in pharmaceutical technology: Lifelong companions

scientific article published on 09 January 2019

Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium

scientific article published on 01 January 2010

Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting

scientific article published on 24 October 2016

Mapping the Interactions among Biomaterials, Adsorbed Proteins, and Human Embryonic Stem Cells.

scientific article published on 9 April 2009

Materials for stem cell factories of the future.

scientific article published on June 2014

Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study

scientific article published on 23 July 2015

Mechanisms of lipid preservation in archaeological clay ceramics revealed by mass spectrometry imaging

scientific article published on 15 June 2020

Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces

scientific article

Molecular Formula Prediction for Chemical Filtering of 3D OrbiSIMS Datasets

scientific article published in 2022

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

scientific article

Multivariate ToF-SIMS image analysis of polymer microarrays and protein adsorption

scientific article published on 6 March 2015

Nanopores in single- and double-layer plasma polymers used for cell guidance in water and protein containing buffer solutions

scientific article published on January 2010

Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles.

scientific article published on 18 July 2012

Organic depth profiling of a binary system: the compositional effect on secondary ion yield and a model for charge transfer during secondary ion emission.

scientific article published in August 2009

Partial least squares regression as a powerful tool for investigating large combinatorial polymer libraries

scientific article

Patterning the mechanical properties of hydrogen silsesquioxane films using electron beam irradiation for application in mechano cell guidance

scientific article

Picoliter water contact angle measurement on polymers

scientific article published on 16 May 2007

Platelet adhesion and procoagulant activity induced by contact with radiofrequency glow discharge polymers: roles of adsorbed fibrinogen and vWF

scientific article published on 01 September 2000

Polymer microarrays for high throughput discovery of biomaterials

scientific article

Polymer microarrays rapidly identify competitive adsorbents of virus-like particles

scientific article published on 17 November 2020

Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays.

scientific article published on 15 September 2010

Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray.

scientific article published on August 2011

Prediction of Broad-spectrum Pathogen Attachment to Coating Materials for Biomedical Devices.

scientific article published in December 2017

Preparation of Caco-2 cell sheets using plasma polymerised acrylic acid as a weak boundary layer

scientific article published on 18 June 2010

Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling

scientific article published on 17 November 2020

Pulsed and continuous wave acrylic acid radio frequency plasma deposits: plasma and surface chemistry.

scientific article published on 13 March 2007

Quantitative XPS depth profiling of codeine loaded poly(l-lactic acid) films using a coronene ion sputter source.

scientific article published on 7 May 2009

Rapid detection of peptide markers for authentication purposes in raw and cooked meat using ambient liquid extraction surface analysis mass spectrometry

scientific article published on 9 October 2014

Rapid micropatterning of cell lines and human pluripotent stem cells on elastomeric membranes

scientific article

Remotely Controlled in Situ Growth of Silver Microwires Forming Bioelectronic Interfaces

scientific article published on 20 February 2019

Revealing cytokine-induced changes in the extracellular matrix with secondary ion mass spectrometry

scientific article

Scaling human pluripotent stem cell expansion and differentiation: are cell factories becoming a reality?

scientific article published on 6 November 2015

Sequential Orbitrap Secondary Ion Mass Spectrometry and Liquid Extraction Surface Analysis-Tandem Mass Spectrometry-Based Metabolomics for Prediction of Brain Tumor Relapse from Sample-Limited Primary Tissue Archives

scientific article published in 2021

Simultaneous Tracking of Pseudomonas aeruginosa Motility in Liquid and at the Solid-Liquid Interface Reveals Differential Roles for the Flagellar Stators

scientific article published on 24 September 2019

Single-Cell Analysis: Visualizing Pharmaceutical and Metabolite Uptake in Cells with Label-Free 3D Mass Spectrometry Imaging.

scientific article published on 23 June 2015

Single-Cell Metabolic Profiling of Macrophages Using 3D OrbiSIMS: Correlations with Phenotype

scientific article published in 2022

Single-Cell Tracking on Polymer Microarrays Reveals the Impact of Surface Chemistry on <i>Pseudomonas aeruginosa</i> Twitching Speed and Biofilm Development

scientific article published on 06 November 2020

Strategies for MCR image analysis of large hyperspectral data-sets

scientific article

Study of the Resistance of SAMs on Aluminium to Acidic and Basic Solutions Using Dynamic Contact Angle Measurement

scientific article published on 01 January 2007

Surface analysis using a new plasma assisted desorption/ionisation source for mass spectrometry in ambient air

scientific article published on 01 June 2012

Surface characterization of carbohydrate microarrays

scientific article published on 18 October 2010

Surface chemistry of a high-copper dental amalgam

scientific article published on 01 December 1998

Surface mass spectrometry of two component drug-polymer systems: novel chromatographic separation method using gentle-secondary ion mass spectrometry (G-SIMS).

scientific article published on 19 April 2011

Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions

scientific article published on 7 November 2011

Synthetic Light-Curable Polymeric Materials Provide a Supportive Niche for Dental Pulp Stem Cells.

scientific article published on 7 December 2017

TOF-SIMS Analysis of a 576 Micropatterned Copolymer Array To Reveal Surface Moieties That Control Wettability

article

Temporal evolution of an electron-free afterglow in the pulsed plasma polymerisation of acrylic acid.

scientific article published on 8 March 2008

The 3D OrbiSIMS-label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power.

scientific article

The impact of surface chemistry modification on macrophage polarisation

scientific article published on 14 June 2016

The influence of nanotexturing of poly(lactic-co-glycolic acid) films upon human ovarian cancer cell attachment

scientific article published on 17 May 2016

The osteogenic response of mesenchymal stem cells to an injectable PLGA bone regeneration system

scientific article

The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles

scientific article published on 10 March 2009

Thermally switchable polymers achieve controlled Escherichia coli detachment

scientific article

ToF-SIMS analysis of chemical heterogenities in inkjet micro-array printed drug/polymer formulations

article

Tryptic digestion coupled with ambient desorption electrospray ionization and liquid extraction surface analysis mass spectrometry enabling identification of skeletal muscle proteins in mixtures and distinguishing between beef, pork, horse, chicken,

scientific article published on 15 April 2014

Ultra-resolution imaging of a self-assembling biomolecular system using robust carbon nanotube AFM probes

scientific article published on 22 February 2007

Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry

scientific article

Use of imaging multivariate analysis to improve biochemical and anatomical discrimination in desorption electrospray ionisation mass spectrometry imaging.

scientific article published on 10 July 2012

Validating a Predictive Structure-Property Relationship by Discovery of Novel Polymers which Reduce Bacterial Biofilm Formation

scientific article published on 03 October 2019

Water contact angle is not a good predictor of biological responses to materials

scientific article published on 6 July 2017

Water-based 3D inkjet printing of an oral pharmaceutical dosage form

scientific article published on 09 April 2019

List of works by Morgan R. Alexander

3D ToF-SIMS imaging of polymer multilayer films using argon cluster sputter depth profiling.

3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling

3D extrusion printing of high drug loading immediate release paracetamol tablets.

3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release

3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles

3D printing of tablets containing multiple drugs with defined release profiles.

3D printing of tablets using inkjet with UV photoinitiation.

A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays.

Ambient DESI and LESA-MS analysis of proteins adsorbed to a biomaterial surface using in-situ surface tryptic digestion.

Analysis and prediction of defects in UV photo-initiated polymer microarrays

Analytical techniques: surface and interfacial characterisation ⬇️

Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers

Attachment of stem cells to scaffold particles for intra-cerebral transplantation

Authentication of processed meat products by peptidomic analysis using rapid ambient mass spectrometry.

Bacterial attachment to polymeric materials correlates with molecular flexibility and hydrophilicity

Bioprinting Using Mechanically Robust Core-Shell Cell-Laden Hydrogel Strands.

Cell spreading correlates with calculated logP of amino acid-modified surfaces

Characterisation of a micro-plasma for ambient mass spectrometry imaging.

Chemical and spatial analysis of protein loaded PLGA microspheres for drug delivery applications

Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4bm00054dClick here for [...]

Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior.

Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells

Combinatorial discovery of polymers resistant to bacterial attachment

Conditional gene expression in human embryonic stem cells

Controlling protein retention on enzyme-responsive surfaces

Correction to Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study.

Desktop 3D printing of controlled release pharmaceutical bilayer tablets

Detection of negative molecular ions in acrylic acid plasma: some implications for polymerization mechanisms

Development and characterization of a stable adhesive bond between a poly(dimethylsiloxane) catheter material and a bacterial biofilm resistant acrylate polymer coating

Development and validation of a fluorescence method to follow the build-up of short peptide sequences on solid 2D surfaces

Dimerization of Tri(4-bromophenyl)benzene by Aryl−Aryl Coupling from Solution on a Gold Surface

Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration

Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation

Discovery of a Novel Polymer for Xeno-Free, Long-Term Culture of Human Pluripotent Stem Cell Expansion

Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays

Dynamics of anterior-posterior axis formation in the developing mouse embryo

Effect of sessile drop volume on the wetting anisotropy observed on grooved surfaces.

Effects of Polymer 3D Architecture, Size, and Chemistry on Biological Transport and Drug Delivery In Vitro and in Orthotopic Triple Negative Breast Cancer Models

Enzyme-activated RGD ligands on functionalized poly(ethylene glycol) monolayers: surface analysis and cellular response.

Extrusion 3D Printing of Paracetamol Tablets from a Single Formulation with Tunable Release Profiles Through Control of Tablet Geometry

Friction Force Microscopy of Alkylphosphonic Acid and Carboxylic Acids Adsorbed on the Native Oxide of Aluminum

Fumed silica nanoparticle mediated biomimicry for optimal cell-material interactions for artificial organ development

High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry

High throughput methods applied in biomaterial development and discovery

High throughput screening for biomaterials discovery

High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays.

High-energy electron beam lithography of octadecylphosphonic acid monolayers on aluminum

Hippocampal cell response to substrates with surface chemistry gradients

Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion.

Image based Machine Learning for identification of macrophage subsets

Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials

Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation

Impact of surface chemistry and topography on the function of antigen presenting cells.

Improved Extraction Repeatability and Spectral Reproducibility for Liquid Extraction Surface Analysis–Mass Spectrometry Using Superhydrophobic–Superhydrophilic Patterning

Influence of the plasma sheath on plasma polymer deposition in advance of a mask and down pores.

Inkjet printing as a novel medicine formulation technique

Intracellular Drug Uptake-A Comparison of Single Cell Measurements Using ToF-SIMS Imaging and Quantification from Cell Populations with LC/MS/MS.

Investigation of cell-surface interactions using chemical gradients formed from plasma polymers.

Lipids and polymers in pharmaceutical technology: Lifelong companions

Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium

Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting

Mapping the Interactions among Biomaterials, Adsorbed Proteins, and Human Embryonic Stem Cells.

Materials for stem cell factories of the future.

Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study

Mechanisms of lipid preservation in archaeological clay ceramics revealed by mass spectrometry imaging

Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces

Molecular Formula Prediction for Chemical Filtering of 3D OrbiSIMS Datasets

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

Multivariate ToF-SIMS image analysis of polymer microarrays and protein adsorption

Nanopores in single- and double-layer plasma polymers used for cell guidance in water and protein containing buffer solutions

Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles.

Organic depth profiling of a binary system: the compositional effect on secondary ion yield and a model for charge transfer during secondary ion emission.

Partial least squares regression as a powerful tool for investigating large combinatorial polymer libraries

Patterning the mechanical properties of hydrogen silsesquioxane films using electron beam irradiation for application in mechano cell guidance

Picoliter water contact angle measurement on polymers

Platelet adhesion and procoagulant activity induced by contact with radiofrequency glow discharge polymers: roles of adsorbed fibrinogen and vWF

Polymer microarrays for high throughput discovery of biomaterials

Polymer microarrays rapidly identify competitive adsorbents of virus-like particles

Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays.