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List of works by Harold M. Aukema

A diet with 35% of energy from protein leads to kidney damage in female Sprague-Dawley rats

scientific article published on 3 May 2011

A dietary conjugated linoleic acid treatment that slows renal disease progression alters renal cyclooxygenase-2-derived prostanoids in the Han: SPRD-cy rat

scientific article published on 21 September 2011

A high mixed protein diet reduces body fat without altering the mechanical properties of bone in female rats

scientific article published on 16 September 2009

Abnormal lipid and fatty acid compositions of kidneys from mice with polycystic kidney disease

scientific article published on June 1, 1992

Adipose tissue oxylipin profiles vary by anatomical site and are altered by dietary linoleic acid in rats

scientific article published on 27 December 2018

Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs

scientific article

Alpha-linolenic acid enhances the phagocytic and secretory functions of alternatively activated macrophages in part via changes to the oxylipin profile

scientific article published on 04 December 2019

Alterations in renal cytosolic phospholipase A2 and cyclooxygenases in polycystic kidney disease

scientific journal article

Anti-inflammatory effects of α-linolenic acid in M1-like macrophages are associated with enhanced production of oxylipins from α-linolenic and linoleic acid.

scientific article published on 3 April 2018

Blood Pressure Lowering Effect of a Pea Protein Hydrolysate in Hypertensive Rats and Humans

scientific article published on 28 September 2011

Butyrate alters activity of specific cAMP-receptor proteins in a transgenic mouse colonic cell line

scientific article published on January 1997

COX-2 expression in cystic kidneys is dependent on dietary n-3 fatty acid composition.

scientific article published on 02 May 2007

Comparative effects of high oleic acid vs high mixed saturated fatty acid obesogenic diets upon PUFA metabolism in mice

scientific article published on 8 March 2017

Conjugated linoleic acid reduces parathyroid hormone in health and in polycystic kidney disease in rats

scientific article published on 01 June 2004

Cyclooxygenase 2 inhibition slows disease progression and improves the altered renal lipid mediator profile in the Pkd2WS25/- mouse model of autosomal dominant polycystic kidney disease

scientific article published on 22 January 2019

Cyclooxygenase product inhibition with acetylsalicylic acid slows disease progression in the Han:SPRD-Cy rat model of polycystic kidney disease

scientific article published on 04 November 2014

Detrimental effects of a high fat diet in early renal injury are ameliorated by fish oil in Han:SPRD-cy rats

scientific article published on 01 January 2003

Diet and disease alter phosphoinositide composition and metabolism in murine polycystic kidneys

scientific article published in May 1995

Dietary ALA, EPA and DHA have distinct effects on oxylipin profiles in female and male rat kidney, liver and serum

scientific article published on 18 April 2018

Dietary LA and sex effects on oxylipin profiles in rat kidney, liver, and serum differ from their effects on PUFAs.

scientific article

Dietary Linoleic Acid and α-Linolenic Acid Differentially Affect Renal Oxylipins and Phospholipid Fatty Acids in Diet-Induced Obese Rats

article

Dietary conjugated linoleic acid reduces PGE2 release and interstitial injury in rat polycystic kidney disease

scientific article published in October 2003

Dietary conjugated linoleic acid renal benefits and possible toxicity vary with isomer, dose and gender in rat polycystic kidney disease

scientific article published on 16 July 2008

Dietary fat and fiber alter rat colonic mucosal lipid mediators and cell proliferation

scientific article published on 01 November 1993

Dietary fat and fiber alter rat colonic protein kinase C isozyme expression

scientific article published on 01 January 1995

Dietary fat and fiber differentially alter intracellular second messengers during tumor devolopment in rat colon

article

Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome

scientific article published on 15 November 2012

Dietary flax oil during pregnancy and lactation retards disease progression in rat offspring with inherited kidney disease

scientific article published on 25 October 2006

Dietary flax oil reduces renal injury, oxidized LDL content, and tissue n-6/n-3 FA ratio in experimental polycystic kidney disease

scientific article

Dietary flax oil rich in α-linolenic acid reduces renal disease and oxylipin abnormalities, including formation of docosahexaenoic acid derived oxylipins in the CD1-pcy/pcy mouse model of nephronophthisis.

scientific article published on 29 November 2014

Dietary modulation of oxylipins in cardiovascular disease and aging

scientific article

Dietary modulation of rat colonic cAMP-dependent protein kinase activity

article

Dietary restriction in moderately obese rats improves body size and glucose handling without the renal and hepatic alterations observed with a high-protein diet

scientific article published in December 2014

Dietary soy protein attenuates renal disease progression after 1 and 3 weeks in Han:SPRD-cy weanling rats

scientific article published in June 2004

Dietary soy protein benefit in experimental kidney disease is preserved after isoflavone depletion of diet

scientific article published on 4 October 2010

Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats.

scientific article

Dietary soy protein effects on inherited polycystic kidney disease are influenced by gender and protein level

scientific article published on 01 February 1999

Dietary soy protein reduces early renal disease progression and alters prostanoid production in obese fa/fa Zucker rats

scientific article published on 25 July 2007

Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease.

scientific article published on 8 May 2009

Dietary soya protein during pregnancy and lactation in rats with hereditary kidney disease attenuates disease progression in offspring

scientific article published on 01 January 2007

Distinct effects of dietary flax compared to fish oil, soy protein compared to casein, and sex on the renal oxylipin profile in models of polycystic kidney disease

scientific article published on 15 July 2017

Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease

scientific article published on 03 February 2011

Early dietary protein restriction slows disease progression and lengthens survival in mice with polycystic kidney disease

scientific article published on 01 December 1994

Effect of dietary supplementation with a fish oil concentrate on the alkenylacyl class of ethanolamine phospholipid in human platelets

scientific article published on 01 January 1989

Effects of dietary conjugated linoleic acid in advanced experimental polycystic kidney disease

scientific article published on 08 September 2008

Effects of dietary protein restriction and oil type on the early progression of murine polycystic kidney disease

scientific article published on 01 October 1992

Effects of flaxseed derivatives in experimental polycystic kidney disease vary with animal gender

scientific article published in December 2006

Elevated levels of pro-inflammatory oxylipins in older subjects are normalized by flaxseed consumption

scientific article published on 18 April 2014

Endogenous synthesis of n-3 PUFA modifies fatty acid composition of kidney phospholipids and eicosanoid levels in the fat-1 mouse

scientific article published on 13 August 2013

Evidence for the use of glomerulomegaly as a surrogate marker of glomerular damage and for alpha-linolenic acid-rich oils in the treatment of early obesity-related glomerulopathy in a diet-induced rodent model of obesity

scientific article published on 19 March 2014

Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors.

scientific article published on 11 April 2015

Feeding flaxseed oil but not secoisolariciresinol diglucoside results in higher bone mass in healthy rats and rats with kidney disease.

scientific article

Ferulaldehyde, a Water-Soluble Degradation Product of Polyphenols, Inhibits the Lipopolysaccharide-Induced Inflammatory Response in Mice

scientific article published on 23 December 2008

Flaxseed consumption reduces blood pressure in patients with hypertension by altering circulating oxylipins via an α-linolenic acid-induced inhibition of soluble epoxide hydrolase.

scientific article published on 28 April 2014

Folate intakes from diet and supplements may place certain Canadians at risk for folic acid toxicity

scientific article published on 9 September 2016

Generation of Bioactive Oxylipins from Exogenously Added Arachidonic, Eicosapentaenoic and Docosahexaenoic Acid in Primary Human Brain Microvessel Endothelial Cells

scientific article published on 06 October 2015

Global Gene Expression Profiling in PPAR-γAgonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease ⬇️

scientific article published on May 13, 2012

High dietary fat intake increases renal cyst disease progression in Han:SPRD-cy rats

scientific article published on 01 September 2000

High dose trans-10,cis-12 CLA increases lean body mass in hamsters, but elevates levels of plasma lipids and liver enzyme biomarkers

scientific article published in November 2011

In vivo formation of polyphosphoinositide isomers and association with progression of murine polycystic kidney disease

article

Increased renal fibrosis and expression of renal phosphatidylinositol 4-kinase-beta and phospholipase C(gamma1) proteins in piglets exposed to ochratoxin-A

scientific article published on 01 January 2004

Intake patterns and dietary associations of soya protein consumption in adults and children in the Canadian Community Health Survey, Cycle 2.2.

scientific article published on 6 January 2015

Lack of Benefit of Early Intervention with Dietary Flax and Fish Oil and Soy Protein in Orthologous Rodent Models of Human Hereditary Polycystic Kidney Disease

scientific article

Late dietary intervention limits benefits of soy protein or flax oil in experimental polycystic kidney disease

scientific article published on 29 June 2007

Linoleic acid derived oxylipins are elevated in kidney and liver and reduced in serum in rats given a high-protein diet

scientific article published on 15 August 2018

Localization of protein kinase C isozymes in rat colon

scientific article published on 01 November 1995

Long-term high intake of whole proteins results in renal damage in pigs.

scientific article published on 28 July 2010

Marked enrichment of the alkenylacyl subclass of plasma ethanolamine glycerophospholipid with eicosapentaenoic acid in human subjects consuming a fish oil concentrate

scientific article published on 01 March 1996

Mass and fatty acid composition of the 3-phosphorylated phosphatidylinositol bisphosphate isomer in stimulated human platelets

scientific article published on 01 July 1993

Mixed compared with single-source proteins in high-protein diets affect kidney structure and function differentially in obese fa/fa Zucker rats

scientific article published on 6 October 2016

Modulation of renal injury in pcy mice by dietary fat containing n-3 fatty acids depends on the level and type of fat.

scientific article

Nutrient and Food Group Intakes of Manitoba Children and Youth: A Population-Based Analysis by Pulse and Soy Consumption Status

scientific article published on 19 July 2016

Nutritional and health benefits of pulses

scientific article

PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease

scientific article (publication date: February 2011)

Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.

scientific article published on 20 May 2009

Protein kinase C isoforms in human and rat colonic mucosa.

scientific article published in August 1994

Protein source in a high-protein diet modulates reductions in insulin resistance and hepatic steatosis in fa/fa Zucker rats.

scientific article published on 6 December 2015

Pulse consumption in Canadian adults influences nutrient intakes

scientific article published in August 2012

Purified dietary n-3 polyunsaturated fatty acids alter diacylglycerol mass and molecular species composition in concanavalin A-stimulated murine splenocytes

scientific article

Renal cyclooxygenase and lipoxygenase products are altered in polycystic kidneys and by dietary soy protein and fish oil treatment in the Han:SPRD-Cy rat.

scientific article published on 30 October 2013

Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis

scientific journal article

Safety of chronic exercise in a rat model of kidney disease

scientific article published on 01 March 2000

Selective COX-2 inhibition markedly slows disease progression and attenuates altered prostanoid production in Han:SPRD-cy rats with inherited kidney disease

scientific article published on 30 May 2007

Selectivity of cyclooxygenase isoform activity and prostanoid production in normal and diseased Han:SPRD-cy rat kidneys.

scientific article published on 18 October 2005

Soy Protein Alleviates Hypertension and Fish Oil Improves Diastolic Heart Function in the Han:SPRD-Cy Rat Model of Cystic Kidney Disease

scientific article published on 01 December 2015

Spleen Oxylipin and Polyunsaturated Fatty Acid Profiles are Altered by Dietary Source of Polyunsaturated Fatty Acid and by Sex

scientific article published on 07 April 2020

Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease

scientific article (publication date: 2013)

The Brain Oxylipin Profile Is Resistant to Modulation by Dietary n-6 and n-3 Polyunsaturated Fatty Acids in Male and Female Rats

scientific article published on 29 January 2019

The effect of flaxseed dose on circulating concentrations of alpha-linolenic acid and secoisolariciresinol diglucoside derived enterolignans in young, healthy adults

scientific article published on 26 March 2015

Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy

scientific article published on 25 October 2014

Trans-8, cis-10+ cis-9, trans-11-conjugated linoleic acid mixture alters body composition in Syrian golden hamsters fed a hypercholesterolaemic diet

scientific article published on 8 July 2010

Tyrosol attenuates ischemia-reperfusion-induced kidney injury via inhibition of inducible nitric oxide synthase

scientific article published on 8 April 2013

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