List of works - John M. Hawdon

A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum

scientific article published on January 2000

A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases

scientific article published on April 2002

Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation

scientific article

Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum

scientific article published in August 2004

Acceptance of the 2016 Henry Baldwin Ward Medal - A Long and Winding Road to a Diet of Worms.

scientific article published on 16 August 2016

Albumin and a Dialyzable Serum Factor Stimulate Feeding In vitro by Third-Stage Larvae of the Canine Hookworm Ancylostoma caninum

scientific article published on August 1, 1991

Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli.

scientific article published on September 1996

Ancylostoma caninum: glutathione stimulates feeding in third-stage larvae by a sulfhydryl-independent mechanism

scientific article published on 01 December 1993

Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro

scientific article published in March 1995

Ancylostoma caninum: reduced glutathione stimulates feeding by third-stage infective larvae

scientific article published in August 1992

Ancylostoma ceylanicum infective third-stage larvae are activated by co-culture with HT-29-MTX intestinal epithelial cells.

scientific article

Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum

scientific article

Characterisation of hookworm heat shock factor binding protein (HSB-1) during heat shock and larval activation.

scientific article

Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation

scientific article

Chemogenomic approach to identifying nematode chemoreceptor drug targets in the entomopathogenic nematode Heterorhabditis bacteriophora

scientific article published on 24 February 2021

Cloning and characterisation of an aspartyl protease inhibitor (API-1) from Ancylostoma hookworms.

scientific article

Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae

scientific article published in January 1995

Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum

scientific article published on 6 February 2004

Comparison of mitochondrial cytochrome oxidase 1 DNA sequences from Necator americanus hookworms maintained for 100 generations in golden hamsters (Mesocricetus auratus) and hookworms from natural human infections

scientific article published in September 2004

Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development.

scientific article published on 19 April 2018

Controlling soil-transmitted helminths: time to think inside the box?

scientific article published on 06 January 2014

Corrigendum to “Ac-FAR-1, a 20kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: Gene transcription pattern, ligand binding properties and structural characterization” [Mol. Biochem. Parasitol. 126 (1) (2

article

Decline in protease activities with age in the nematode Caenorhabditis elegans

scientific article published on November 1988

Differentiation between the human hookworms Ancylostoma duodenale and Necator americanus using PCR-RFLP.

scientific article published in August 1996

Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae

scientific article published on August 2003

Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine

scientific article published on August 2002

Efficacy of an ivermectin/pyrantel pamoate chewable formulation against the canine hookworms, Uncinaria stenocephala and Ancylostoma caninum

scientific article published in February 1992

Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity ofNecatorInfection in Hainan Province, People’s Republic of China

article

Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study

scientific article published on 01 September 1999

Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China

article

Experimental approaches to the development of a recombinant hookworm vaccine.

scientific article

Expression profile of heat shock response factors during hookworm larval activation and parasitic development.

scientific article

Genome of the human hookworm Necator americanus

scientific article

Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus

article

Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans daf-c paradigm

scientific article published on 01 January 1993

Hookworm: developmental biology of the infectious process.

scientific article

Hookworms in the Americas: An alternative to trans-Pacific contact.

scientific article published in February 1996

Hyaluronidases of the gastrointestinal invasive nematodes Ancylostoma caninum and Anisakis simplex: possible functions in the pathogenesis of human zoonoses.

scientific article published in October 1994

Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum.

scientific article

Identification of candidate infection genes from the model entomopathogenic nematode Heterorhabditis bacteriophora

scientific article

Identification of hookworm DAF-16/FOXO response elements and direct gene targets

scientific article

Improving eukaryotic genome annotation using single molecule mRNA sequencing

scientific article published in March 2018

Introduction of Gerhard A. Schad as the recipient of the Clark P. Read Mentor Award

scientific article published on December 2005

Investigating hookworm genomes by comparative analysis of two Ancylostoma species ⬇️

scientific article

Isolation and characterization of a naturally occurring multidrug-resistant strain of the canine hookworm, Ancylostoma caninum

scientific article published on 14 February 2019

Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research

scientific article published on 15 September 2016

Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum

scientific article

Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms.

scientific article published on 07 October 2008

Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms.

scientific article

Observations on the feeding behaviour of parasitic third-stage hookworm larvae

scientific article published on 01 February 1993

Phosphoinositide-3-OH-kinase inhibitor LY294002 prevents activation of Ancylostoma caninum and Ancylostoma ceylanicum third-stage infective larvae.

scientific article

Plant vermicides of Haitian Vodou show in vitro activity against larval hookworm

scientific article published in October 2008

Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative

scientific article

RNA and protein synthesis is required for Ancylostoma caninum larval activation

scientific article

RNAi-mediated gene knockdown by microinjection in the model entomopathogenic nematode Heterorhabditis bacteriophora

scientific article published on 18 March 2016

Refined ab initio gene predictions of Heterorhabditis bacteriophora using RNA-seq.

scientific article published on 9 March 2018

Resumption of feeding in vitro by hookworm third-stage larvae: a comparative study

scientific article published on 01 December 1992

Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing.

scientific article published on 17 January 2018

Soil-transmitted helminthiases: implications of climate change and human behavior.

scientific article

Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes

scientific article

The second messenger cyclic GMP mediates activation in Ancylostoma caninum infective larvae

scientific article published on July 2003

Transformational Principles for NEON Sampling of Mammalian Parasites and Pathogens: A Response to Springer and Colleagues

Transgenic C. elegans dauer larvae expressing hookworm phospho null DAF-16/FoxO exit dauer

scientific article

Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression.

scientific article

Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms

scientific article

Vaccination with alum-precipitated recombinant Ancylostoma-secreted protein 1 protects mice against challenge infections with infective hookworm (Ancylostoma caninum) larvae.

scientific article

Vaccines for hookworm infection

scientific article published on October 1997

List of works by John M. Hawdon

A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum

A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases

Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation

Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum

Acceptance of the 2016 Henry Baldwin Ward Medal - A Long and Winding Road to a Diet of Worms.

Albumin and a Dialyzable Serum Factor Stimulate Feeding In vitro by Third-Stage Larvae of the Canine Hookworm Ancylostoma caninum

Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli.

Ancylostoma caninum: glutathione stimulates feeding in third-stage larvae by a sulfhydryl-independent mechanism

Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro

Ancylostoma caninum: reduced glutathione stimulates feeding by third-stage infective larvae

Ancylostoma ceylanicum infective third-stage larvae are activated by co-culture with HT-29-MTX intestinal epithelial cells.

Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum

Characterisation of hookworm heat shock factor binding protein (HSB-1) during heat shock and larval activation.

Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation

Chemogenomic approach to identifying nematode chemoreceptor drug targets in the entomopathogenic nematode Heterorhabditis bacteriophora

Cloning and characterisation of an aspartyl protease inhibitor (API-1) from Ancylostoma hookworms.

Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae

Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum

Comparison of mitochondrial cytochrome oxidase 1 DNA sequences from Necator americanus hookworms maintained for 100 generations in golden hamsters (Mesocricetus auratus) and hookworms from natural human infections

Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development.

Controlling soil-transmitted helminths: time to think inside the box?

Corrigendum to “Ac-FAR-1, a 20kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: Gene transcription pattern, ligand binding properties and structural characterization” [Mol. Biochem. Parasitol. 126 (1) (2

Decline in protease activities with age in the nematode Caenorhabditis elegans

Differentiation between the human hookworms Ancylostoma duodenale and Necator americanus using PCR-RFLP.

Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae

Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine

Efficacy of an ivermectin/pyrantel pamoate chewable formulation against the canine hookworms, Uncinaria stenocephala and Ancylostoma caninum

Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity ofNecatorInfection in Hainan Province, People’s Republic of China

Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study

Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China

Experimental approaches to the development of a recombinant hookworm vaccine.

Expression profile of heat shock response factors during hookworm larval activation and parasitic development.

Genome of the human hookworm Necator americanus

Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus

Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans daf-c paradigm

Hookworm: developmental biology of the infectious process.

Hookworms in the Americas: An alternative to trans-Pacific contact.

Hyaluronidases of the gastrointestinal invasive nematodes Ancylostoma caninum and Anisakis simplex: possible functions in the pathogenesis of human zoonoses.

Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum.

Identification of candidate infection genes from the model entomopathogenic nematode Heterorhabditis bacteriophora

Identification of hookworm DAF-16/FOXO response elements and direct gene targets

Improving eukaryotic genome annotation using single molecule mRNA sequencing

Introduction of Gerhard A. Schad as the recipient of the Clark P. Read Mentor Award

Investigating hookworm genomes by comparative analysis of two Ancylostoma species ⬇️

Isolation and characterization of a naturally occurring multidrug-resistant strain of the canine hookworm, Ancylostoma caninum

Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research

Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum

Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms.

Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms.

Observations on the feeding behaviour of parasitic third-stage hookworm larvae

Phosphoinositide-3-OH-kinase inhibitor LY294002 prevents activation of Ancylostoma caninum and Ancylostoma ceylanicum third-stage infective larvae.

Plant vermicides of Haitian Vodou show in vitro activity against larval hookworm

Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative

RNA and protein synthesis is required for Ancylostoma caninum larval activation

RNAi-mediated gene knockdown by microinjection in the model entomopathogenic nematode Heterorhabditis bacteriophora

Refined ab initio gene predictions of Heterorhabditis bacteriophora using RNA-seq.

Resumption of feeding in vitro by hookworm third-stage larvae: a comparative study

Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing.

Soil-transmitted helminthiases: implications of climate change and human behavior.

Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes

The second messenger cyclic GMP mediates activation in Ancylostoma caninum infective larvae

Transformational Principles for NEON Sampling of Mammalian Parasites and Pathogens: A Response to Springer and Colleagues

Transgenic C. elegans dauer larvae expressing hookworm phospho null DAF-16/FoxO exit dauer

Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression.

Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms

Vaccination with alum-precipitated recombinant Ancylostoma-secreted protein 1 protects mice against challenge infections with infective hookworm (Ancylostoma caninum) larvae.

Vaccines for hookworm infection