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List of works by Minna U Kaikkonen

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Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

2011 thesis
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

scientific article published on August 2013
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

scientific article published on 02 June 2013
Non-coding RNAs as regulators of gene expression and epigenetics.

scientific article
Effect of natural genetic variation on enhancer selection and function.

scientific article published on 13 October 2013
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

scientific article
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.

scientific article published on 23 August 2012
Avidin-biotin technology in targeted therapy

scientific article published on May 2010
NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids

scientific article
SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism

scientific article published on 21 December 2016
Truncated vesicular stomatitis virus G protein improves baculovirus transduction efficiency in vitro and in vivo

scientific article
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

scientific article
Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.

scientific article published on 2 November 2015
Quantification of nascent transcription by bromouridine immunocapture nuclear run-on RT-qPCR.

scientific article published on 16 July 2015
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription.

scientific article published on 28 July 2015
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

article
Post-transcriptional regulatory element boosts baculovirus-mediated gene expression in vertebrate cells

scientific article
Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model.

scientific article published on 18 September 2014
Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

scientific article
Non-invasive Imaging in Gene Therapy

scientific article published on 19 June 2007
Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment

scientific article
Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study

scientific article published on 17 June 2015
Screening of complement inhibitors: shielded baculoviruses increase the safety and efficacy of gene delivery

scientific article
(Strept)avidin-displaying lentiviruses as versatile tools for targeting and dual imaging of gene delivery

scientific article
Baculovirus-mediated immediate-early gene expression and nuclear reorganization in human cells

scientific article published on 27 November 2007
Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots

scientific article published on 19 July 2016
In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles

scientific article published on 7 February 2012
Targeting and purification of metabolically biotinylated baculovirus

scientific article
Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-κB cistrome to reprogram the prostate cancer cell transcriptome.

scientific article published on 26 September 2016
SPECT/CT imaging of baculovirus biodistribution in rat.

scientific article published on 5 April 2007
Avidin fusion protein-expressing lentiviral vector for targeted drug delivery

scientific article published in August 2009
Vespucci: a system for building annotated databases of nascent transcripts

scientific article published on 04 December 2013
Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8.

scientific article
Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle

scientific article
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

scientific article published in September 2017
Culture medium induced vimentin reorganization associates with enhanced baculovirus-mediated gene delivery

Aggravated Postinfarct Heart Failure in Type 2 Diabetes Is Associated with Impaired Mitophagy and Exaggerated Inflammasome Activation.

scientific article published on 18 September 2017
Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions.

scientific article published on 4 December 2017
Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia.

scientific article published on 29 August 2016
Deletion of Lymphangiogenic and Angiogenic Growth Factor VEGF-D Leads to Severe Hyperlipidemia and Delayed Clearance of Chylomicron Remnants

scientific article published on 01 October 2018
How to avoid complement attack in baculovirus-mediated gene delivery

scientific article published on July 2011
Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells

scientific article
Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets.

scientific article
Differential but Complementary HIF1α and HIF2α Transcriptional Regulation

scientific article published on 09 May 2018
Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction

scientific article published in June 2017
Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity

scientific article published on 22 May 2015
Targeted delivery via avidin fusion protein: intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes

scientific article
Biodistribution and antitumor effect of Cetuximab-targeted lentivirus

scientific article published on 18 October 2013
Distribution and dynamics of transcription-associated proteins during parvovirus infection

scientific article
Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells

scientific article published on 05 November 2018

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