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List of works by Francesca Fallarino

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CTLA-4-Ig regulates tryptophan catabolism in vivo.

scientific article published on 30 September 2002
Modulation of tryptophan catabolism by regulatory T cells.

scientific article published on 26 October 2003
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22.

scientific article published in August 2013
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

scientific article published on 01 June 2006
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

scientific journal article
T cell apoptosis by tryptophan catabolism

scientific article published in October 2002
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

scientific journal article
Tolerance, DCs and tryptophan: much ado about IDO

scientific article (publication date: May 2003)
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

scientific article
Aryl hydrocarbon receptor control of a disease tolerance defence pathway

scientific article
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

scientific article published on 08 April 2007
Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.

scientific article published in May 2010
IL-22 defines a novel immune pathway of antifungal resistance.

scientific article published on 5 May 2010
Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism

scientific article published in February 2006
TLRs govern neutrophil activity in aspergillosis

scientific article published in December 2004
Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc.

scientific article published in November 2007
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.

scientific article published on 3 October 2004
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.

scientific article published on 8 December 2005
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

scientific article
Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host

scientific article published on 25 October 2008
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.

scientific article published on 25 July 2010
Indoleamine 2,3‐dioxygenase: From catalyst to signaling function

scientific article published on August 1, 2012
TLR3 essentially promotes protective class I-restricted memory CD8⁺ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

scientific article published on 6 December 2011
B7-1 Engagement of Cytotoxic T Lymphocyte Antigen 4 Inhibits T Cell Activation in the Absence of CD28

scientific article published on July 6, 1998
Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans

scientific article published on 6 May 2009
Thymosin 1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance

scientific article published on 01 June 2006
IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi

scientific article published on April 2008
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

scientific article published on 13 February 2017
IDO mediates TLR9-driven protection from experimental autoimmune diabetes.

scientific article published on 19 October 2009
Tryptophan catabolism generates autoimmune-preventive regulatory T cells

scientific article published on 10 October 2006
A crucial role for tryptophan catabolism at the host/Candida albicans interface.

scientific article
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.

scientific article published in January 2013
Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines

scientific article published on 4 October 2005
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

scientific article published in Nature Communications
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes

scientific article published on 01 July 2007
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

scientific article published on 01 May 2019
Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

scientific article published on 11 February 2014
Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis

scientific article
Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines.

scientific article
Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis.

scientific article published on 18 November 2009
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.

scientific article published on 19 September 2005
Topical application of soluble CD83 induces IDO-mediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival

scientific article published on 12 July 2013
Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.

scientific article
Toll-like receptor 9-mediated induction of the immunosuppressive pathway of tryptophan catabolism.

scientific article
Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype

scientific article published on 27 October 2015
Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

scientific article published on 12 March 2015
Tryptophan Feeding of the IDO1-AhR Axis in Host-Microbial Symbiosis

scientific article published on 15 December 2014
Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism.

scientific article published on 18 September 2007
Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers

scientific article published on 16 April 2015
Thymosin alpha1: the regulator of regulators?

scientific article published on April 2010

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