List of works - Oriana Tabarrini

(1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents

scientific article published on 01 March 2000

1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

scientific article published on 05 March 2020

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

scientific article published on 28 May 2013

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction

scientific article published on 17 August 2018

2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

scientific article published on June 2009

6-Aminoquinolones as new potential anti-HIV agents.

scientific article

6-Aminoquinolones: A New Class of Quinolone Antibacterials?

scientific article published on 01 March 1995

6-Aminoquinolones: photostability, cellular distribution and phototoxicity.

scientific article published in October 2004

6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis

scientific article published on 10 September 2012

6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors.

scientific article published on July 2010

7-(Disubstituted thiazolyl)-3,5-dihydroxy-6-heptenoic/heptanoic acid derivatives as HMG-COa reductase inhibitors

scientific article published on 01 August 1994

A 1,8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication

scientific article

A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity

scientific article published on 17 November 2008

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits

scientific article published on 20 April 2015

A novel and efficient approach to discriminate between pre- and post-transcription HIV inhibitors

scientific article published on 23 February 2005

Accounting for target flexibility and water molecules by docking to ensembles of target structures: the HCV NS5B palm site I inhibitors case study.

scientific article

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

scientific article published in October 2005

Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type K(ATP)-channel openers

scientific article published in October 2005

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

scientific article published on 01 December 2020

Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation

scientific article published on 8 September 2005

Chemometric Methodologies in a Quantitative Structure−Activity Relationship Study: The Antibacterial Activity of 6-Aminoquinolones

article published in 1997

Chemometric rationalization of the structural and physicochemical basis for selective cyclooxygenase-2 inhibition: toward more specific ligands.

scientific article

Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

scientific article (publication date: September 2008)

Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.

scientific article published on 21 October 2013

Design and synthesis of modified quinolones as antitumoral acridones.

scientific article published on June 1999

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment

scientific article published on 11 June 2013

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives

scientific article published on 13 September 2017

Ethyl 1,8-naphthyridone-3-carboxylates downregulate human papillomavirus-16 E6 and E7 oncogene expression.

scientific article

Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of theS. aureusNorA Efflux Pump

scientific article published on 03 August 2011

Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.

scientific article published on 22 July 2014

From cromakalim to different structural classes of K(ATP) channel openers.

scientific article

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

article

From small to powerful: the fragments universe and its "chem-appeal".

scientific article

Highly Potent 1,4-Benzo-thiazine Derivatives as KATP-Channel Openers

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers

scientific article published in August 2003

In vitro phototoxic properties of new 6-desfluoro and 6-fluoro-8-methylquinolones

scientific article published on December 2002

Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor

scientific article published on May 2009

Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules

scientific article published in 2022

Modulation of HIV-1-induced activation of plasmacytoid dendritic cells by 6-desfluoroquinolones

scientific article published on 09 December 2013

Molecular view of ligands specificity for CAG repeats in anti-Huntington therapy

scientific article published on 10 September 2015

New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors

scientific article

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

scientific article

Novel in vivo model for the study of human immunodeficiency virus type 1 transcription inhibitors: evaluation of new 6-desfluoroquinolone derivatives

scientific article published on 22 January 2007

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors

scientific article

Potent 6-Desfluoro-8-methylquinolones as New Lead Compounds in Antibacterial Chemotherapy1

scientific article published on 01 December 1996

Pyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors.

scientific article

QSAR study and VolSurf characterization of anti-HIV quinolone library.

scientific article

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance

scientific article published on 13 June 2013

Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.

scientific article published on 5 March 2018

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues

scientific article published on 9 June 2017

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly

scientific article published on 13 December 2013

Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity

scientific article published on 12 May 2011

Structure modifications of 6-aminoquinolones with potent anti-HIV activity

scientific article

Structure-activity relationship study on anti-HIV 6-desfluoroquinolones

scientific article published on 19 August 2008

Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication

scientific article

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

scientific article published on November 2010

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position

Studies on 6-Aminoquinolones: synthesis and antibacterial evaluation of 6-amino-8-ethyl- and 6-amino-8-methoxyquinolones

scientific article published on 01 November 1999

Studies on anti-HIV quinolones: New insights on the C-6 position

article

Synthesis and anti-BVDV activity of acridones as new potential antiviral agents

scientific article published in April 2006

Synthesis and antibacterial evaluation of [1,3]benzothiazino[3,2-a]quinoline- and [3,1]benzothiazino[1,2-a]quinoline-6-carboxylic acid derivatives

scientific article published on 01 July 1997

Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition.

scientific article

Synthesis and chromatographic enantioresolution of anti-HIV quinolone derivatives

article

The 6-Aminoquinolone WC5 inhibits different functions of the immediate-early 2 (IE2) protein of human cytomegalovirus that are essential for viral replication

scientific article published on 25 August 2014

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

scientific article published on March 2010

The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.

scientific article published on 14 January 2015

The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors

scientific article

Velnacrine thiaanalogues as potential agents for treating Alzheimer's disease

scientific article

List of works by Oriana Tabarrini

(1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents

1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction

2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

6-Aminoquinolones as new potential anti-HIV agents.

6-Aminoquinolones: A New Class of Quinolone Antibacterials?

6-Aminoquinolones: photostability, cellular distribution and phototoxicity.

6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis

6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors.

7-(Disubstituted thiazolyl)-3,5-dihydroxy-6-heptenoic/heptanoic acid derivatives as HMG-COa reductase inhibitors

A 1,8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication

A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits

A novel and efficient approach to discriminate between pre- and post-transcription HIV inhibitors

Accounting for target flexibility and water molecules by docking to ensembles of target structures: the HCV NS5B palm site I inhibitors case study.

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type K(ATP)-channel openers

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation

Chemometric Methodologies in a Quantitative Structure−Activity Relationship Study: The Antibacterial Activity of 6-Aminoquinolones

Chemometric rationalization of the structural and physicochemical basis for selective cyclooxygenase-2 inhibition: toward more specific ligands.

Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.

Design and synthesis of modified quinolones as antitumoral acridones.

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives

Ethyl 1,8-naphthyridone-3-carboxylates downregulate human papillomavirus-16 E6 and E7 oncogene expression.

Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of theS. aureusNorA Efflux Pump

Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.

From cromakalim to different structural classes of K(ATP) channel openers.

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

From small to powerful: the fragments universe and its "chem-appeal".

Highly Potent 1,4-Benzo-thiazine Derivatives as KATP-Channel Openers

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers

In vitro phototoxic properties of new 6-desfluoro and 6-fluoro-8-methylquinolones

Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor

Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules

Modulation of HIV-1-induced activation of plasmacytoid dendritic cells by 6-desfluoroquinolones

Molecular view of ligands specificity for CAG repeats in anti-Huntington therapy

New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

Novel in vivo model for the study of human immunodeficiency virus type 1 transcription inhibitors: evaluation of new 6-desfluoroquinolone derivatives

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors

Potent 6-Desfluoro-8-methylquinolones as New Lead Compounds in Antibacterial Chemotherapy1

Pyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors.

QSAR study and VolSurf characterization of anti-HIV quinolone library.

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance

Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly

Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity

Structure modifications of 6-aminoquinolones with potent anti-HIV activity

Structure-activity relationship study on anti-HIV 6-desfluoroquinolones

Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position

Studies on 6-Aminoquinolones: synthesis and antibacterial evaluation of 6-amino-8-ethyl- and 6-amino-8-methoxyquinolones

Studies on anti-HIV quinolones: New insights on the C-6 position

Synthesis and anti-BVDV activity of acridones as new potential antiviral agents

Synthesis and antibacterial evaluation of [1,3]benzothiazino[3,2-a]quinoline- and [3,1]benzothiazino[1,2-a]quinoline-6-carboxylic acid derivatives

Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition.

Synthesis and chromatographic enantioresolution of anti-HIV quinolone derivatives

The 6-Aminoquinolone WC5 inhibits different functions of the immediate-early 2 (IE2) protein of human cytomegalovirus that are essential for viral replication

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.

The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors

Velnacrine thiaanalogues as potential agents for treating Alzheimer's disease