List of works - Serena Massari

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

scientific article published on 28 May 2013

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction

scientific article published on 17 August 2018

2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

scientific article published on June 2009

6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis

scientific article published on 10 September 2012

6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors.

scientific article published on July 2010

A 1,8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication

scientific article

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits

scientific article published on 20 April 2015

Blocking HIV-1 replication by targeting the Tat-hijacked transcriptional machinery

scientific article

Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions

scientific article published on 06 March 2019

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

scientific article published on 01 December 2020

Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.

scientific article published on 21 October 2013

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment

scientific article published on 11 June 2013

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives

scientific article published on 13 September 2017

Ethyl 1,8-naphthyridone-3-carboxylates downregulate human papillomavirus-16 E6 and E7 oncogene expression.

scientific article

Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.

scientific article published on 22 July 2014

From 6-aminoquinolone antibacterials to 6-amino-7-thiopyranopyridinylquinolone ethyl esters as inhibitors of Staphylococcus aureus multidrug efflux pumps

scientific article published in June 2010

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

article

From small to powerful: the fragments universe and its "chem-appeal".

scientific article

Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions

scientific article published on 12 October 2020

Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor

scientific article published on May 2009

Modulation of HIV-1-induced activation of plasmacytoid dendritic cells by 6-desfluoroquinolones

scientific article published on 09 December 2013

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors

scientific article

Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase

scientific article

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance

scientific article published on 13 June 2013

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues

scientific article published on 9 June 2017

Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors

scientific article published on 24 September 2020

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly

scientific article published on 13 December 2013

Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity

scientific article published on 12 May 2011

Structure-activity relationship study on anti-HIV 6-desfluoroquinolones

scientific article published on 19 August 2008

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

scientific article published on November 2010

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position

Studies on anti-HIV quinolones: New insights on the C-6 position

article

Synthesis and chromatographic enantioresolution of anti-HIV quinolone derivatives

article

The 6-Aminoquinolone WC5 inhibits different functions of the immediate-early 2 (IE2) protein of human cytomegalovirus that are essential for viral replication

scientific article published on 25 August 2014

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

scientific article published on March 2010

The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.

scientific article published on 14 January 2015

List of works by Serena Massari

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction

2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis

6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors.

A 1,8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits

Blocking HIV-1 replication by targeting the Tat-hijacked transcriptional machinery

Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives

Ethyl 1,8-naphthyridone-3-carboxylates downregulate human papillomavirus-16 E6 and E7 oncogene expression.

Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.

From 6-aminoquinolone antibacterials to 6-amino-7-thiopyranopyridinylquinolone ethyl esters as inhibitors of Staphylococcus aureus multidrug efflux pumps

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

From small to powerful: the fragments universe and its "chem-appeal".

Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions

Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor

Modulation of HIV-1-induced activation of plasmacytoid dendritic cells by 6-desfluoroquinolones

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors

Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues

Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly

Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity

Structure-activity relationship study on anti-HIV 6-desfluoroquinolones

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position

Studies on anti-HIV quinolones: New insights on the C-6 position

Synthesis and chromatographic enantioresolution of anti-HIV quinolone derivatives

The 6-Aminoquinolone WC5 inhibits different functions of the immediate-early 2 (IE2) protein of human cytomegalovirus that are essential for viral replication

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.