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List of works by José I Martín-Subero

A 2 Mb deletion in 14q13 associated with severe developmental delay and hemophagocytic lymphohistiocytosis

scientific article published on 16 June 2011

A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.

scientific article published on 25 August 2014

A DNA methylation fingerprint of 1628 human samples

scientific article

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling

scientific article published in June 2006

A chromosomal translocation in cyclin D1-negative/cyclin D2-positive mantle cell lymphoma fuses the CCND2 gene to the IGK locus

article

A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation

scientific article published on 10 May 2007

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms

scientific article

A familial disorder of altered DNA-methylation

scientific article published on 10 April 2014

ALK-positive diffuse large B-cell lymphoma is associated with Clathrin-ALK rearrangements: report of 6 cases

scientific article published on 22 May 2003

ALK-positive diffuse large B-cell lymphoma with ALK-Clathrin fusion belongs to the spectrum of pediatric lymphomas

scientific article published on 01 October 2005

Aberrant DNA methylation profile of chronic and transformed classic Philadelphia-negative myeloproliferative neoplasms.

scientific article published on 28 May 2013

Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.

scientific article

Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma

scientific article published on August 2006

Amplification of ERBB2, RARA, and TOP2A genes in a myelodysplastic syndrome transforming to acute myeloid leukemia.

scientific article

Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2-positive germinal center B-cell lymphomas.

scientific article

Androgen Receptor Mutations Are Associated with Altered Epigenomic Programming as Evidenced by HOXA5 Methylation

scientific article published on 11 February 2011

Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes

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Array-based DNA methylation profiling of primary lymphomas of the central nervous system

scientific article

Assessment of SOX11 expression in routine lymphoma tissue sections: characterization of new monoclonal antibodies for diagnosis of mantle cell lymphoma.

scientific article

BCL2 and BCL3 are recurrent translocation partners of the IGH locus

scientific article published on 01 October 2008

BCL6 alternative breakpoint region break and homozygous deletion of 17q24 in the nodular lymphocyte predominance type of Hodgkin's lymphoma-derived cell line DEV.

scientific article published on June 2006

Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).

scientific article

Breakpoint characterization of the der(19)t(11;19)(q13;p13) in the ovarian cancer cell line SKOV-3.

scientific article published on 30 January 2013

CD95 and TRAF2 promote invasiveness of pancreatic cancer cells.

scientific article published on 24 January 2005

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells.

scientific article published on 22 October 2015

Centrosome abnormalities in ALK-positive anaplastic large-cell lymphoma

scientific article published on 01 November 2004

Characterization of homozygous deletions in laryngeal squamous cell carcinoma cell lines.

scientific article

Chromosomal Breakpoints Affecting Immunoglobulin Loci Are Recurrent in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin Lymphoma

scientific article published on 01 November 2006

Chromosomal abnormalities clustering in multiple myeloma reveals cytogenetic subgroups with nonrandom acquisition of chromosomal changes

scientific article published on 01 March 2004

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma

scientific article published on 01 July 2006

Clinical features of maternal uniparental disomy 14 in patients with an epimutation and a deletion of the imprintedDLK1/GTL2gene cluster

article

Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q

scientific article published on 16 August 2007

Combining array-based approaches for the identification of candidate tumor suppressor loci in mature lymphoid neoplasms.

scientific article published on October 2007

Comparative genomic hybridization and amplotyping by arbitrarily primed PCR in stage A B-CLL

scientific article published on 01 October 2001

Cytogenetic and molecular characterization of a patient with simultaneous B-cell chronic lymphocytic leukemia and peripheral T-cell lymphoma

scientific article published on 01 December 2001

Cytogenetic and molecular characterization of simultaneous chronic and acute myelocytic leukemia

scientific article published on 01 April 2003

DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis

scientific article

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

scientific article

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

scientific article published on 12 June 2015

DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease.

scientific article published on 11 September 2013

DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia

scientific article

Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage.

scientific article published on November 2016

Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies

scientific article published on 11 May 2010

Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization.

scientific article

Detection of secondary genetic aberrations in follicle center cell derived lymphomas: assessment of the reliability of comparative genomic hybridization and standard chromosome analysis

scientific article published on 01 January 2001

Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.

scientific article

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

scientific article published in November 2016

Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21).

scientific article

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

scientific article published on 28 January 2021

ETS1 encoding a transcription factor involved in B-cell differentiation is recurrently deleted and down-regulated in classical Hodgkin's lymphoma

scientific article published on 11 May 2012

Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications.

scientific article

Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies

scientific article

Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.

scientific article

Epigenetic signatures associated with different levels of differentiation potential in human stem cells

scientific article

Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia

scientific article

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

scientific article published on 14 October 2012

Epigenomic profiling in polycythaemia vera and essential thrombocythaemia shows low levels of aberrant DNA methylation

scientific article published on 06 August 2011

Expression of ELF1, a lymphoid ETS domain-containing transcription factor, is recurrently lost in classical Hodgkin lymphoma

scientific article published on 25 January 2019

Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma

scientific article published on 01 May 2005

Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

scientific article

Four patients with speech delay, seizures and variable corpus callosum thickness sharing a 0.440 Mb deletion in region 1q44 containing the HNRPU gene.

scientific article published on 9 April 2010

Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia

scientific article

Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma

scientific article published on 2 January 2003

Gains of the proto-oncogene BCL11A and nuclear accumulation of BCL11A(XL) protein are frequent in primary mediastinal B-cell lymphoma.

scientific article

Gains ofREL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein

scientific article published on 01 April 2007

GeneChip analyses point to novel pathogenetic mechanisms in mantle cell lymphoma

scientific article

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism.

scientific article published on 10 August 2016

Genetic and epigenetic basis of chronic lymphocytic leukemia ⬇️

scientific article published on July 1, 2013

Genome-wide methylation analyses identify a subset of mantle cell lymphoma with a high number of methylated CpGs and aggressive clinicopathological features.

scientific article published on 16 July 2013

High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma

scientific article published on 01 April 2007

Hunting for the 5th base: Techniques for analyzing DNA methylation

scientific article published on 09 February 2009

Identification of candidate tumor-suppressor genes in 6q27 by combined deletion mapping and electronic expression profiling in lymphoid neoplasms

scientific article published on August 2003

Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines

scientific article published on 30 July 2008

Identification of recurrent chromosomal breakpoints in multiple myeloma with complex karyotypes by combined G-banding, spectral karyotyping, and fluorescence in situ hybridization analyses

scientific article published on 01 September 2006

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

scientific article published on 09 August 2019

Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci

scientific article published on 01 March 2002

Interphase FISH for the detection of breakpoints in IG loci and chromosomal changes with adverse prognostic impact in multiple myeloma with normal karyotypes

scientific article published on 01 June 2006

Interphase cytogenetic characterization of aberrations in the long arm of chromosome 1 in B-cell lymphoid malignancies

scientific article published on 01 July 2003

Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer

scientific article published on 09 August 2013

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

scientific article published on 21 October 2013

Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression

scientific article published on 26 September 2012

MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression

scientific article

Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome

scientific article

Microarray-based DNA methylation analysis of imprinted loci in a patient with transient neonatal diabetes mellitus

scientific article published on 01 December 2008

Molecular cytogenetic analysis of chromosomal breakpoints in the IGH, MYC, BCL6, and MALT1 gene loci in primary cutaneous B-cell lymphomas

scientific article

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia

scientific article

NF-κB activation impairs somatic cell reprogramming in ageing

scientific article published on 27 July 2015

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

scientific article

Non-coding recurrent mutations in chronic lymphocytic leukaemia

scientific article published in Nature

PVRL2 is translocated to theTRA@ locus in t(14;19)(q11;q13)-positive peripheral T-cell lymphomas

scientific article published on 01 November 2007

Partial uniparental disomy: a recurrent genetic mechanism alternative to chromosomal deletion in malignant lymphoma

scientific article published on 01 May 2006

Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia.

scientific article

Rare occurrence of biallelic CYLD gene mutations in classical Hodgkin lymphoma

scientific article

Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.

scientific article

Recurrent loss of the Y chromosome and homozygous deletions within the pseudoautosomal region 1: association with male predominance in mantle cell lymphoma

scientific article published on 01 June 2008

Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A-TCRAD juxtaposition

scientific article published in July 2009

SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

scientific article published on 15 January 2013

Segmental chromosomal aberrations and centrosome amplifications: pathogenetic mechanisms in Hodgkin and Reed–Sternberg cells of classical Hodgkin's lymphoma?

scientific article published on 01 November 2003

Simultaneous translocations of FGFR3/MMSET and CCND1 into two different IGH alleles in multiple myeloma: lack of concurrent activation of both proto-oncogenes.

scientific article published on May 2007

Systematic benchmarking of single-cell ATAC-sequencing protocols

scientific article published in 2023

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia

scientific article

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

scientific article

The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

scientific article published on 21 November 2013

The pattern of genomic gains in salivary gland MALT lymphomas

scientific article

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

scientific article published on 02 November 2020

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

scientific article published on 21 May 2018

Towards defining the lymphoma methylome

scientific article published on 01 October 2006

Transcriptional Profiling of the Nuclear Factor-κB Pathway Identifies a Subgroup of Primary Lymphoma of the Central Nervous System With Low BCL10 Expression

scientific article published on 01 March 2007

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia

scientific article

Trisomy 19 is associated with trisomy 12 and mutatedIGHVgenes in B-chronic lymphocytic leukaemia

scientific article published on 01 July 2007

Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma.

scientific article

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

scientific article

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

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microRNA expression profiles identify subtypes of mantle cell lymphoma with different clinicobiological characteristics

scientific article published on 02 May 2013

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