List of works - James A. Duce

17Beta-estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult

scientific article

A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe(2+) under physiologically relevant conditions.

scientific article published on 23 August 2014

A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease

scientific article published on June 2010

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

scientific article (publication date: September 1999)

Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey

scientific article

Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brain

scientific article published on 29 June 2005

Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels.

scientific article

Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons

scientific article published on 23 December 2015

Amyloidogenic processing of Alzheimer's disease β-amyloid precursor protein induces cellular iron retention

scientific article published on 22 May 2020

Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics

scientific article published on 02 May 2010

Ceruloplasmin and β-amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron.

scientific article published on 7 February 2014

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease.

scientific article published on 19 February 2013

Changes in cortical protein markers of iron transport with gender, major depressive disorder and suicide

scientific article published on 30 January 2019

Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide

scientific article published in October 2006

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

scientific article published in January 2005

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine.

scientific article published on 13 November 2013

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model

scientific article published on 27 October 2011

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease

scientific article published on 24 October 2011

Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey

scientific article published in January 2008

Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis

article

Iron accumulates in Huntington's disease neurons: protection by deferoxamine

scientific article

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

scientific article

Linker histone H1 binds to disease associated amyloid-like fibrils

scientific article

Lithium suppression of tau induces brain iron accumulation and neurodegeneration. ⬇️

scientific article published on 12 July 2016

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

scientific article published on 01 October 2018

Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology

scientific article

Mitochondria in aging and Alzheimer's disease.

scientific article published on September 2007

Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.

scientific article

Oxidation of Iron under Physiologically Relevant Conditions in Biological Fluids from Healthy and Alzheimer's Disease Subjects ⬇️

scientific article published on 28 December 2016

P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid

scientific article

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

scientific article

Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis

scientific article published on 22 February 2019

Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease ⬇️

scientific article

Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators ⬇️

scientific article

Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model

article

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

scientific article published on 29 January 2012

The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing

scientific article published on 16 August 2021

The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders

scientific article published on 21 April 2014

The proteostasis network provides targets for neurodegeneration

scientific article published on 23 May 2019

The role of metallobiology and amyloid-β peptides in Alzheimer's disease

scientific article

β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin

scientific article

List of works by James A. Duce

17Beta-estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult

A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe(2+) under physiologically relevant conditions.

A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey

Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brain

Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels.

Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons

Amyloidogenic processing of Alzheimer's disease β-amyloid precursor protein induces cellular iron retention

Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics

Ceruloplasmin and β-amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron.

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease.

Changes in cortical protein markers of iron transport with gender, major depressive disorder and suicide

Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine.

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease

Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey

Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis

Iron accumulates in Huntington's disease neurons: protection by deferoxamine

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

Linker histone H1 binds to disease associated amyloid-like fibrils

Lithium suppression of tau induces brain iron accumulation and neurodegeneration. ⬇️

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology

Mitochondria in aging and Alzheimer's disease.

Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.

Oxidation of Iron under Physiologically Relevant Conditions in Biological Fluids from Healthy and Alzheimer's Disease Subjects ⬇️

P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis

Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease ⬇️

Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators ⬇️

Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing

The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders

The proteostasis network provides targets for neurodegeneration

The role of metallobiology and amyloid-β peptides in Alzheimer's disease

β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin