List of works - Katia Todoerti

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

scientific article published in July 2009

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.

scientific article

A progression-risk score to predict treatment-free survival for early stage chronic lymphocytic leukemia patients.

scientific article published on 9 December 2015

Biological and clinical relevance of miRNA expression signatures in primary plasma cell leukemia.

scientific article

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

scientific article published on 20 May 2010

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

scientific article

Compendium of FAM46C gene mutations in plasma cell dyscrasias.

scientific article

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia

scientific article published on 6 May 2009

Dioxin exposure of human CD34+ hemopoietic cells induces gene expression modulation that recapitulates its in vivo clinical and biological effects

scientific article

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.

scientific article

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma.

scientific article

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

scientific article published on 4 December 2009

Does adiponectin act as an antiangiogenic factor in B-cell chronic lymphocytic leukemia?

scientific article published on 27 August 2009

Effects of enzastaurin, alone or in combination, on signaling pathway controlling growth and survival of B-cell lymphoma cell lines

scientific article published on April 2010

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

scientific article published on 17 June 2016

Gene array profile identifies collagen type XV as a novel human osteoblast-secreted matrix protein

scientific article published in August 2009

Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma

scientific article

Gene expression profiling reveals novel protective effects of Aminaphtone on ECV304 endothelial cells

scientific article published on 12 April 2016

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

scientific article

Genome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles

article

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

scientific article published on 23 November 2010

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma.

scientific article published in December 2009

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

scientific article published on 25 September 2015

Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules

scientific article published on 23 November 2012

Impact of host genes and strand selection on miRNA and miRNA* expression.

scientific article

Improved risk stratification in myeloma using a microRNA-based classifier.

scientific article published on 30 May 2013

In vitro anti-leukaemia activity of sphingosine kinase inhibitor

scientific article published on 19 November 2008

Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

scientific article published on 14 October 2010

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

scientific article published on June 2009

Is ZAP70 still a key prognostic factor in early stage chronic lymphocytic leukaemia? Results of the analysis from a prospective multicentre observational study

scientific article published on 11 September 2014

Lenalidomide and low-dose dexamethasone for newly diagnosed primary plasma cell leukemia

scientific article published on 20 August 2013

Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells

scientific article published on 02 September 2010

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine

scientific article

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

scientific article published on 01 September 2008

Molecular and transcriptional characterization of the novel 17p11.2-p12 amplicon in multiple myeloma.

scientific article published on December 2007

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

scientific article published on 5 November 2013

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

scientific article

Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature

scientific article

Molecular targeting of the PKC-beta inhibitor enzastaurin (LY317615) in multiple myeloma involves a coordinated downregulation of MYC and IRF4 expression

scientific article

Notch pathway promotes ovarian cancer growth and migration via CXCR4/SDF1α chemokine system

scientific article published on 30 July 2015

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations

article

Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b

scientific article

Primary Plasma Cell Leukemia: Identity Card 2016.

scientific article published on April 2016

Primary plasma cell leukemia 2.0: advances in biology and clinical management.

scientific article

Prognostic relevance of serum levels and cellular expression of adiponectin in B-cell chronic lymphocytic leukemia

scientific article published on 27 September 2008

Prospective validation of predictive value of abdominal computed tomography scan on time to first treatment in Rai 0 chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study

scientific article published on 31 March 2015

Serum thrombopoietin compared with ZAP-70 and immunoglobulin heavy-chain gene mutation status as a predictor of time to first treatment in early chronic lymphocytic leukemia

article

Single-agent Smac-mimetic compounds induce apoptosis in B chronic lymphocytic leukaemia (B-CLL)

scientific article

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells

scientific article published on 8 May 2012

The clinical and biological features of a series of immunophenotypic variant of B-CLL

scientific article published on 08 April 2010

The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma.

scientific article

The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.

scientific article published on 25 October 2010

The reconstruction of transcriptional networks reveals critical genes with implications for clinical outcome of multiple myeloma

scientific article

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

scientific article published on 29 April 2015

Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma

scientific article published on October 2005

Transcriptional characterization of a prospective series of primary plasma cell leukemia revealed signatures associated with tumor progression and poorer outcome.

scientific article published on 18 April 2013

Transcriptional features of multiple myeloma patients with chromosome 1q gain

scientific article published on 22 February 2007

Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma

scientific article

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

scientific article published on 08 February 2016

List of works by Katia Todoerti

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.

A progression-risk score to predict treatment-free survival for early stage chronic lymphocytic leukemia patients.

Biological and clinical relevance of miRNA expression signatures in primary plasma cell leukemia.

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

Compendium of FAM46C gene mutations in plasma cell dyscrasias.

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia

Dioxin exposure of human CD34+ hemopoietic cells induces gene expression modulation that recapitulates its in vivo clinical and biological effects

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma.

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

Does adiponectin act as an antiangiogenic factor in B-cell chronic lymphocytic leukemia?

Effects of enzastaurin, alone or in combination, on signaling pathway controlling growth and survival of B-cell lymphoma cell lines

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Gene array profile identifies collagen type XV as a novel human osteoblast-secreted matrix protein

Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma

Gene expression profiling reveals novel protective effects of Aminaphtone on ECV304 endothelial cells

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

Genome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma.

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules

Impact of host genes and strand selection on miRNA and miRNA* expression.

Improved risk stratification in myeloma using a microRNA-based classifier.

In vitro anti-leukaemia activity of sphingosine kinase inhibitor

Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

Is ZAP70 still a key prognostic factor in early stage chronic lymphocytic leukaemia? Results of the analysis from a prospective multicentre observational study

Lenalidomide and low-dose dexamethasone for newly diagnosed primary plasma cell leukemia

Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

Molecular and transcriptional characterization of the novel 17p11.2-p12 amplicon in multiple myeloma.

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature

Molecular targeting of the PKC-beta inhibitor enzastaurin (LY317615) in multiple myeloma involves a coordinated downregulation of MYC and IRF4 expression

Notch pathway promotes ovarian cancer growth and migration via CXCR4/SDF1α chemokine system

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations

Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b

Primary Plasma Cell Leukemia: Identity Card 2016.

Primary plasma cell leukemia 2.0: advances in biology and clinical management.

Prognostic relevance of serum levels and cellular expression of adiponectin in B-cell chronic lymphocytic leukemia

Prospective validation of predictive value of abdominal computed tomography scan on time to first treatment in Rai 0 chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study

Serum thrombopoietin compared with ZAP-70 and immunoglobulin heavy-chain gene mutation status as a predictor of time to first treatment in early chronic lymphocytic leukemia

Single-agent Smac-mimetic compounds induce apoptosis in B chronic lymphocytic leukaemia (B-CLL)

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells

The clinical and biological features of a series of immunophenotypic variant of B-CLL

The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma.

The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.

The reconstruction of transcriptional networks reveals critical genes with implications for clinical outcome of multiple myeloma

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma

Transcriptional characterization of a prospective series of primary plasma cell leukemia revealed signatures associated with tumor progression and poorer outcome.

Transcriptional features of multiple myeloma patients with chromosome 1q gain

Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.