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List of works by Lubor Borsig

A novel carbohydrate-deficient glycoprotein syndrome characterized by a deficiency in glucosylation of the dolichol-linked oligosaccharide

scientific article

A novel pVHL-independent but NEMO-driven pathway in renal cancer promotes HIF stabilization

scientific article published on 26 October 2015

Altered tumor-cell glycosylation promotes metastasis

scientific article published on 13 February 2014

Analysis of SM4 sulfatide as a P-selectin ligand using model membranes

scientific article

Antimetastatic Properties of Low Molecular Weight Heparin

scientific article

Antimetastatic activities of heparins and modified heparins. Experimental evidence.

scientific article published on April 2010

Antimetastatic activities of modified heparins: selectin inhibition by heparin attenuates metastasis.

scientific article published on July 2007

Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment

scientific article

Ascidian dermatan sulfates attenuate metastasis, inflammation and thrombosis by inhibition of P-selectin.

scientific article published on September 2011

Breastfed at Tiffany's.

scientific article published on 17 March 2016

Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins

scientific article published on 12 February 2012

Cell-specific and nuclear targeting with [M(CO)(3)](+) (M=(99m)Tc, Re)-based complexes conjugated to acridine orange and bombesin

scientific article published on 01 January 2007

Complete absence of the αGal xenoantigen and isoglobotrihexosylceramide in α1,3galactosyltransferase knock-out pigs.

scientific article published on May 2012

Decoding breast milk oligosaccharides.

scientific article published on 19 February 2014

Deletion of L-selectin increases atherosclerosis development in ApoE-/- mice

scientific article

Distinct selectin ligands on colon carcinoma mucins can mediate pathological interactions among platelets, leukocytes, and endothelium

scientific article published on August 1999

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

scientific article

Endothelial chemokine receptors as facilitators of tumor cell extravasation?

scientific article published on September 2012

Expression and purification of His-tagged beta-1,4-galactosyltransferase in yeast and in COS cells

scientific article published on 01 November 1997

Heparanase in Cancer Metastasis - Heparin as a Potential Inhibitor of Cell Adhesion Molecules

scientific article published on 01 January 2020

Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

scientific article

Heparin as an inhibitor of cancer progression.

scientific article published on January 2010

Heparin attenuates metastasis mainly due to inhibition of P- and L-selectin, but non-anticoagulant heparins can have additional effects

scientific article published on January 2007

Heparins attenuate cancer metastasis: are selectins the link?

scientific article published on June 2009

IL17A-Mediated Endothelial Breach Promotes Metastasis Formation

scientific article published on 19 November 2015

Immunodetection of alpha 1-3 fucosyltransferase (FucT-V).

scientific article published on May 1996

Immunodetection of glycosyltransferases: prospects and pitfalls.

scientific article published on January 1998

Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins

scholarly article

Increasing the antitumor effect of an EpCAM-targeting fusion toxin by facile click PEGylation

scientific article published on November 2013

Inflammatory chemokines and metastasis—tracing the accessory ⬇️

scientific article published on July 15, 2013

Inhibition of chemokine receptor CCR2 reduces sarcoma cell transendothelial migration and metastasis to the lungs.

scientific article published on 7 August 2015

Inhibitory effect of non-anticoagulant heparin (S-NACH) on pancreatic cancer cell adhesion and metastasis in human umbilical cord vessel segment and in mouse model

scientific article

L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest

scientific article published in February 2006

Low infiltration of tumor-associated macrophages in high c-Myb-expressing breast tumors

scientific article published on 12 August 2019

Metal complex mediated conjugation of peptides to nucleus targeting acridine orange: a modular concept for dual-modality imaging agents

scientific article published on 2 May 2011

Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites

scientific article published on 9 December 2013

Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c+ cells through TLR4

scientific article published on 07 October 2013

Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization. ⬇️

scientific article

Molecular basis of metastasis

scientific article published on 01 April 2009

Monocyte Induction of E-Selectin-Mediated Endothelial Activation Releases VE-Cadherin Junctions to Promote Tumor Cell Extravasation in the Metastasis Cascade

scientific article published on 3 August 2016

Non-anticoagulant effects of heparin in carcinoma metastasis and Trousseau's syndrome.

scientific article

Nuclear heparanase-1 activity suppresses melanoma progression via its DNA-binding affinity

scientific article

Ontogenetic regulation of leukocyte recruitment in mouse yolk sac vessels

scientific article published on 22 March 2013

P-selectin deficiency attenuates tumor growth and metastasis ⬇️

scientific article published on August 4, 1998

P-selectin mediates metastatic progression through binding to sulfatides on tumor cells

scientific article

P-selectin- and heparanase-dependent antimetastatic activity of non-anticoagulant heparins

scientific article published on 8 June 2007

Pathways of metastasizing intestinal cancer cells revealed: how will fighting metastases at the site of cancer cell arrest affect drug development?

scientific article published in January 2013

Pictures in molecular medicine: three-dimensional visualization of intravascular tumor cells in mice

scientific article published on 01 August 2001

Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression

scientific article published on 01 February 2008

Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.

scientific article published on 20 September 2010

Recombinant Soluble beta-1,4-Galactosyltransferases Expressed in Saccharomyces cerevisiae. Purification, Characterization and Comparison with Human Enzyme

scientific article published on 01 July 1996

Scaled-up expression of human alpha 2,6(N)sialyltransferase in Saccharomyces cerevisiae.

scientific article published in May 1995

Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment

scientific article published on 19 March 2007

Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas

scientific article

Selectins as mediators of lung metastasis.

scientific article

Selectins facilitate carcinoma metastasis and heparin can prevent them.

scientific article published on February 2004

Selectins in cancer immunity.

scientific article published on 20 December 2017

Selectins promote tumor metastasis.

scientific article published on 07 May 2010

Single cell polarity in liquid phase facilitates tumour metastasis.

scientific article published on 28 February 2018

Sulfated Hexasaccharides Attenuate Metastasis by Inhibition of P-selectin and Heparanase ⬇️

scientific article published on May 1, 2011

Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis

scientific article published on 01 June 2018

Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis.

scientific article published on 29 October 2015

The role of VLA-4 binding for experimental melanoma metastasis and its inhibition by heparin.

scientific article published on 26 February 2014

The role of platelet activation in tumor metastasis.

scientific article published on August 2008

Trafficking and localization studies of recombinant alpha1, 3-fucosyltransferase VI stably expressed in CHO cells

scientific article published on 01 March 1998

Transcription factor c-Myb inhibits breast cancer lung metastasis by suppression of tumor cell seeding.

scientific article published on 30 October 2017

Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line

scientific article

Trifunctional 99mTc based radiopharmaceuticals: metal-mediated conjugation of a peptide with a nucleus targeting intercalator

scientific article published on 24 December 2010

Tumor attenuation by combined heparan sulfate and polyamine depletion.

scientific article

Tunicate Heparan Sulfate Enriched in 2-Sulfated β-Glucuronic Acid: Structure, Anticoagulant Activity, and Inhibitory Effect on the Binding of Human Colon Adenocarcinoma Cells to Immobilized P-Selectin

scientific article published on 12 June 2019

VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes

scientific article published on 28 November 2014

VWF fibers induce thrombosis during cancer

scientific article

Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.

scientific article

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