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List of works by Xianghuo He

A LIN28B Tumor-Specific Transcript in Cancer

scientific article published in February 2018

ASJA: A Program for Assembling Splice Junctions Analysis

scientific article published on 07 August 2019

Acetylcholinesterase, a key prognostic predictor for hepatocellular carcinoma, suppresses cell growth and induces chemosensitization

scientific article published on 3 January 2011

Altered gene expression profiles of NIH3T3 cells regulated by human lung cancer associated gene CT120.

scientific article published on December 2004

Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma

scientific article published on 03 December 2013

An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin

scientific article published on 24 December 2019

Analysis of acetylcholine, choline and butyrobetaine in human liver tissues by hydrophilic interaction liquid chromatography-tandem mass spectrometry

scientific article published on 29 February 2008

Application of microRNA and mRNA expression profiling on prognostic biomarker discovery for hepatocellular carcinoma

scientific article

Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis

scientific article published on 12 November 2018

CXCR6 upregulation contributes to a proinflammatory tumor microenvironment that drives metastasis and poor patient outcomes in hepatocellular carcinoma.

scientific article

Choline transporters in human lung adenocarcinoma: expression and functional implications

scientific article published on September 2007

Ciliary neurotrophic factor receptor alpha subunit-modulated multiple downstream signaling pathways in hepatic cancer cell lines and their biological implications

scientific article

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

scientific article published on 3 July 2015

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

scientific article published on 6 April 2016

Cloning and characterization of human IC53-2, a novel CDK5 activator binding protein.

scientific article

Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines

scientific article published on 26 August 2019

Comprehensive transcriptome analysis identifies novel molecular subtypes and subtype-specific RNAs of triple-negative breast cancer

scientific article published on 15 March 2016

Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKbeta overexpression in human breast cancers

scientific article published on 01 November 2006

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

scientific article published on 26 March 2007

Development of a highly metastatic model that reveals a crucial role of fibronectin in lung cancer cell migration and invasion

scientific article

Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma

scientific article

Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma

scientific article published on 22 August 2011

Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex.

scientific article

GNAI1 Suppresses Tumor Cell Migration and Invasion and is Post-Transcriptionally Regulated by Mir-320a/c/d in Hepatocellular Carcinoma.

scientific article published on December 2012

GNAI3 inhibits tumor cell migration and invasion and is post-transcriptionally regulated by miR-222 in hepatocellular carcinoma.

scientific article published on 13 November 2014

Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the HDAC6-TRIM28-ZNF354C Corepressor Complex

scientific article published on 01 September 2020

Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA

scientific article published on 21 March 2010

Genome-wide analysis of long noncoding RNA (lncRNA) expression in hepatoblastoma tissues

scientific article published on 17 January 2014

Genome-wide analysis reveals that exon methylation facilitates its selective usage in the human transcriptome

scientific article published on 01 September 2018

Genome-wide copy number analyses identified novel cancer genes in hepatocellular carcinoma

scientific article published on 24 August 2011

Genome-wide screening identified that miR-134 acts as a metastasis suppressor by targeting integrin β1 in hepatocellular carcinoma

scientific article (publication date: 2014)

Genome-wide screening reveals that miR-195 targets the TNF-α/NF-κB pathway by down-regulating IκB kinase alpha and TAB3 in hepatocellular carcinoma

scientific article published on 26 June 2013

Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expression.

scientific article published on 19 January 2018

Histone lysine methyltransferase, suppressor of variegation 3-9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA-125b

scientific article published on 6 December 2012

Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response

scientific article published on 21 January 2020

Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

scientific article published on September 2011

Hypoxia-inducible microRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma

scientific article

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

scientific article

Inflammation-induced LINC00665 increases the malignancy through activating PKR/NF-κB pathway in hepatocellular carcinoma

scientific article published on 21 February 2020

Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma

scientific article

Integrative Analyses Identify Osteopontin, LAMB3 and ITGB1 as Critical Pro-Metastatic Genes for Lung Cancer ⬇️

scientific article published on February 18, 2013

Integrative analysis of transcriptional regulatory network and copy number variation in intrahepatic cholangiocarcinoma

scientific article

LncRNA ID2-AS1 suppresses tumor metastasis by activating the HDAC8/ID2 pathway in hepatocellular carcinoma

scientific article published on 13 November 2019

LncRNA RP11-295G20.2 regulates hepatocellular carcinoma cell growth and autophagy by targeting PTEN to lysosomal degradation

scientific article published on 14 December 2021

LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α

scientific article published on 15 October 2020

Long noncoding RNA TSLNC8 is a tumor suppressor that inactivates the interleukin-6/STAT3 signaling pathway

scientific article published on 26 July 2017

Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-κB pathway in hepatocellular carcinoma.

scientific article

Macro-management of microRNAs in cell cycle progression of tumor cells and its implications in anti-cancer therapy ⬇️

scientific article published on September 12, 2011

MetaLnc9 Facilitates Lung Cancer Metastasis via a PGK1-Activated AKT/mTOR Pathway

scientific article published on 18 September 2017

MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene

scientific article

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer.

scientific article

MiR-525-3p enhances the migration and invasion of liver cancer cells by downregulating ZNF395.

scientific article

MicroRNA-124 reduces the pentose phosphate pathway and proliferation by targeting PRPS1 and RPIA mRNAs in human colorectal cancer cells.

scientific article published on 3 August 2015

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2.

scientific article published in November 2010

MicroRNA-127-5p targets the biliverdin reductase B/nuclear factor-κB pathway to suppress cell growth in hepatocellular carcinoma cells

scientific article published on 28 December 2015

MicroRNA-129-5p Regulates Glycolysis and Cell Proliferation by Targeting the Glucose Transporter SLC2A3 in Gastric Cancer Cells.

scientific article published on 15 May 2018

MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancer

scientific article published on 12 October 2011

MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions

scientific article published on 29 June 2010

MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway.

scientific article published on 27 January 2014

MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma

scientific article published on 01 March 2010

MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer

scientific article

MicroRNA-409 suppresses tumour cell invasion and metastasis by directly targeting radixin in gastric cancers

scientific article

MicroRNA-423 promotes cell growth and regulates G 1 /S transition by targeting p21Cip1/Waf1 in hepatocellular carcinoma ⬇️

scientific article published on September 1, 2011

MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma

scientific article

MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma

scientific article published on 22 March 2011

Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism.

scientific article

Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1.

scientific article

Molecular cloning and characterization of the human ASB-8 gene encoding a novel member of ankyrin repeat and SOCS box containing protein family

scientific article published on January 2003

Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region

scientific article

Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

scientific article published on 10 May 2007

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α.

scientific article published on 28 July 2015

Plasma extracellular vesicle long RNA profiling identifies a diagnostic signature for the detection of pancreatic ductal adenocarcinoma

scientific article published on 27 September 2019

Predicting Value of ALCAM as a Target Gene of microRNA-483-5p in Patients with Early Recurrence in Hepatocellular Carcinoma

scientific article published in January 2017

Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway

scientific article published on 30 April 2018

Quantitative proteomic analysis identifies CPNE3 as a novel metastasis-promoting gene in NSCLC.

scientific article published on 6 June 2013

Quantitative proteomic analysis of the metastasis-inhibitory mechanism of miR-193a-3p in non-small cell lung cancer

scientific article

Real-time imaging nuclear translocation of Akt1 in HCC cells

scientific article

Role of microRNAs in inflammation-associated liver cancer

scientific article published on December 2016

SERPINA5 inhibits tumor cell migration by modulating the fibronectin-integrin β1 signaling pathway in hepatocellular carcinoma

scientific article published on 18 December 2013

SRTdb: an omnibus for human tissue and cancer-specific RNA transcripts

scientific article published on 26 April 2022

Speckle-type POZ protein is negatively associated with malignancies and inhibits cell proliferation and migration in liver cancer.

scientific article published on 10 July 2015

Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma.

scientific article

Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma

scientific article published on 09 December 2019

Suppression of Human Liver Cancer Cell Migration and Invasion via the GABAA Receptor

scientific article published on June 2012

TRIM35 Interacts with pyruvate kinase isoform M2 to suppress the Warburg effect and tumorigenicity in hepatocellular carcinoma

scientific article published on 29 September 2014

The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.

scientific article published on 20 April 2018

The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation

scientific article published on 06 March 2019

The role of microRNAs in liver cancer progression.

scientific article

Transcriptome-Wide Analysis Reveals the Landscape of Aberrant Alternative Splicing Events in Liver Cancer

scientific article published on 18 December 2018

Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma.

scientific article

Tumor-Specific Transcripts Are Frequently Expressed in Hepatocellular Carcinoma With Clinical Implication and Potential Function

scientific article published on 12 August 2019

Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells

scientific article

cDNA expression array analysis of gene expression in human hepatocarcinoma Hep3B cells induced by BNIPL-1

scientific article

exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes.

scientific article published on 9 October 2017

miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression.

scientific article

miRNA-200c inhibits invasion and metastasis of human non-small cell lung cancer by directly targeting ubiquitin specific peptidase 25

scientific article

microRNA-202-3p inhibits cell proliferation by targeting ADP-ribosylation factor-like 5A in human colorectal carcinoma

scientific article published on 10 December 2013

microRNAs: tiny RNA molecules, huge driving forces to move the cell ⬇️

scientific article published on November 9, 2010

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