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List of works by Jan-Ingvar Jönsson

ABCB1 haplotypes do not influence transport or efficacy of tyrosine kinase inhibitors in vitro

scientific article published on 20 August 2013

Absence of hot spot mutations of the PIK3CA gene in acute myeloid leukaemia

scientific article published on 27 March 2006

BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.

scientific article

Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells

scientific article

Characterization of the mouse myeloid-associated differentiation marker (MYADM) gene: promoter analysis and protein localization

scientific article published in September 2005

Characterization, chromosomal localization, and expression during hematopoietic differentiation of the gene encoding Arl6ip, ADP-ribosylation-like factor-6 interacting protein (ARL6)

scientific journal article

Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis

scientific article

Deficiency of activating Fcγ-receptors reduces hepatic clearance and deposition of IC and increases CIC levels in mercury-induced autoimmunity

scientific article

FLT3 ligand regulates apoptosis through AKT-dependent inactivation of transcription factor FoxO3.

scientific article published on June 2004

Flt3 ligand induces the outgrowth of Mac-1+B220+ mouse bone marrow progenitor cells restricted to macrophage differentiation that coexpress early B cell-associated genes

scientific article published on 01 November 1999

Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture.

scientific article published on 4 February 2010

Hypoxic and normoxic in vitro cultures maintain similar numbers of long-term reconstituting hematopoietic stem cells from mouse bone marrow

scientific article published on 20 July 2012

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.

scientific article published on 7 June 2011

Inactivation of the forkhead transcription factor FoxO3 is essential for PKB-mediated survival of hematopoietic progenitor cells by kit ligand

scientific article published on April 2003

Interleukin-1β induced activation of the hypothalamus-pituitary-adrenal axis is dependent on interleukin-1 receptors on non-hematopoietic cells

scientific article published on 26 March 2014

Interleukin-6 primarily produced by non-hematopoietic cells mediates the lipopolysaccharide-induced febrile response

scientific article published on July 2013

Interleukin-7 responsiveness of B220+ B cell precursors from bone marrow decreases in aging mice

scientific article published on 01 April 1993

Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells.

scientific article published on 9 September 2010

Irreversible pan-ERBB inhibitor canertinib elicits anti-leukaemic effects and induces the regression of FLT3-ITD transformed cells in mice

scientific article published on 16 August 2011

Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells

scientific article published on 23 November 2009

Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells

scientific article published on 7 August 2012

Phosphatidylinositol 3-kinase is essential for kit ligand-mediated survival, whereas interleukin-3 and flt3 ligand induce expression of antiapoptotic Bcl-2 family genes

scientific article published on August 2003

Pyruvate dehydrogenase kinase 1 is essential for transplantable mouse bone marrow hematopoietic stem cell and progenitor function

scientific article

Single-nucleotide polymorphisms of ABCG2 increase the efficacy of tyrosine kinase inhibitors in the K562 chronic myeloid leukemia cell line

scientific article published on January 2014

Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim.

scientific article published on 26 April 2005

Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol.

scientific article

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells

scientific article

The LIM-only protein LMO4 modulates the transcriptional activity of HEN1

scientific article

The Lim-only protein LMO2 acts as a positive regulator of erythroid differentiation

scientific article published on 22 October 2007

The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production

scientific article

The basic helix-loop-helix transcription factor TAL1/SCL inhibits the expression of the p16INK4A and pTalpha genes

scientific article published on December 2003

The hematopoietic stem cell niche: low in oxygen but a nice place to be.

scientific article published on January 2010

The pan-ErbB receptor tyrosine kinase inhibitor canertinib induces ErbB-independent apoptosis in human leukemia (HL-60 and U-937) cells

scientific article published on 22 January 2010

The pan-ErbB tyrosine kinase inhibitor canertinib induces caspase-mediated cell death in human T-cell leukemia (Jurkat) cells

scientific article published on 6 June 2011

The regulatory domain of protein kinase Ctheta localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cells

scientific article published in June 2003

miR-20b regulates expression of proteinase-activated receptor-1 (PAR-1) thrombin receptor in melanoma cells

scientific article published on 6 February 2014

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