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List of works by Adam Škarka

Anthracycline resistance mediated by reductive metabolism in cancer cells: the role of aldo-keto reductase 1C3.

scientific article published on 14 May 2014

Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase

scientific article published in May 2011

Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions.

scientific article

Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme

scientific article published on 28 March 2020

Enzyme stereospecificity as a powerful tool in searching for new enzymes

scientific article published on July 2010

Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells

scientific article published on 20 October 2015

Human DHRS7, promising enzyme in metabolism of steroids and retinoids?

scientific article published in January 2016

Hydroxysteroid dehydrogenases (HSDs) in bacteria: a bioinformatic perspective

scientific article published on 22 August 2011

Isoquinoline alkaloids as a novel type of AKR1C3 inhibitors

scientific article published on 24 April 2014

Molecular and biochemical characterisation of human short-chain dehydrogenase/reductase member 3 (DHRS3).

scientific article published on 29 October 2014

Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin.

scientific article published on 25 July 2009

Pharmacokinetic interactions of breast cancer chemotherapeutics with human doxorubicin reductases.

scientific article published on 15 May 2015

Purification and reconstitution of human membrane-bound DHRS7 (SDR34C1) from Sf9 cells

scientific article published on 4 December 2013

Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physicochemical properties and efficient reactivation of human acetylcholinesterase inhibited by several nerve agents

scientific article published on 20 November 2018

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

scientific article published in December 2021

Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes

scientific article published on 17 March 2017

The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines.

scientific article

The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells.

scientific article published on 21 August 2015

The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice

scientific article

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