List of works by Pedro Cruz

Adenovirus vector production and purification

scientific article published on December 2010

Characterization and downstream processing of HIV-1 core and virus-like-particles produced in serum free medium

article

Downstream processing of lentiviral vectors: releasing bottlenecks.

scientific article

Editorial [Hot topic: GMP Production of Gene and Cell Therapy Therapeutics (Guest Editors: Manuel Carrondo and Pedro Cruz)]

article

Effect of medium sugar source on the production of retroviral vectors for gene therapy.

scientific article published on May 2006

Effect of viscosity upon hydrodynamically controlled natural aggregates of animal cells grown in stirred vessels

scientific article published on 01 September 1995

From retroviral vector production to gene transfer: spontaneous inactivation is caused by loss of reverse transcription capacity.

scientific article published on April 2008

Human amniocyte-derived cells are a promising cell host for adenoviral vector production under serum-free conditions

scientific article published on May 2015

Human umbilical cord tissue-derived mesenchymal stromal cells attenuate remodeling after myocardial infarction by proangiogenic, antiapoptotic, and endogenous cell-activation mechanisms

scientific article

Hybrid semi-parametric mathematical systems: bridging the gap between systems biology and process engineering.

scientific article published on 15 August 2007

Integrated process optimization: lessons from retrovirus and virus-like particle production.

scientific article published in November 2002

Integrated strategy for the production of therapeutic retroviral vectors

scientific article published on 2 March 2011

Manufacturing of retroviruses

scientific article published on January 2011

Production of retroviral vectors: review

scientific article published on December 2010

Purification of adenoviral vectors using expanded bed chromatography.

scientific article published on 2 November 2005

Purification of recombinant rotavirus VP7 glycoprotein for the study of in vitro rotavirus-like particles assembly

scientific article published on 7 September 2008

Purification of retroviral vectors for clinical application: biological implications and technological challenges

scientific article published on 31 July 2006

Quantitation of MLV-based retroviral vectors using real-time RT-PCR.

scientific article

Regulation of ENaC biogenesis by the stress response protein SERP1.

scientific article

Relevance of an academic GMP Pan-European vector infra-structure (PEVI).

scientific article published on December 2010

Removal of envelope protein-free retroviral vectors by anion-exchange chromatography to improve product quality

scientific article

Repeated-batch cultures of baby hamster kidney cell aggregates in stirred vessels.

scientific article published on January 1994

Retrovirus producer cell line metabolism: implications on viral productivity.

scientific article published on 6 April 2006

Scale-up of virus-like particles production: effects of sparging, agitation and bioreactor scale on cell growth, infection kinetics and productivity.

scientific article published on January 2004

Scaleable purification process for gene therapy retroviral vectors

scientific article published on April 2007

Screening anion-exchange chromatographic matrices for isolation of onco-retroviral vectors.

scientific article published on 11 May 2006

Screening of novel excipients for improving the stability of retroviral and adenoviral vectors.

scientific article published on March 2006

Self-assembled 3D spheroids and hollow-fibre bioreactors improve MSC-derived hepatocyte-like cell maturation in vitro.

scientific article

Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer

scientific article

The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells.

scientific article published on December 2016

Triple layered rotavirus VLP production: kinetics of vector replication, mRNA stability and recombinant protein production.

scientific article published on 14 July 2005

Umbilical cord tissue-derived mesenchymal stromal cells maintain immunomodulatory and angiogenic potencies after cryopreservation and subsequent thawing

scientific article published on 28 December 2016

Paulina is supported by:

About Paulina

Help