List of works - Blake R. Peterson

11beta-alkyl-Delta9-19-nortestosterone derivatives: high-affinity ligands and potent partial agonists of the androgen receptor

scientific article published on October 2004

A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives

scientific article published on 17 August 2007

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

scientific article published in November 1996

A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity

scientific article published in September 2002

A synthetic membrane-anchored antigen efficiently promotes uptake of antifluorescein antibodies and associated protein a by mammalian cells.

scientific article published in December 2001

A synthetic mimic of human Fc receptors: defined chemical modification of cell surfaces enables efficient endocytic uptake of human immunoglobulin-G.

scientific article published on September 2006

An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane

scientific article published in October 2004

Analysis of protein tyrosine kinase inhibitors in recombinant yeast lacking the ERG6 gene

scientific article

Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail

scientific article published in January 2008

Antibody-Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome-Disruptive Peptide

scientific article published on 31 July 2019

Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics.

scientific article

Augmenting vitamin D to combat genetic disease.

scientific article

Calcium flux in neuroblastoma cells is a coupling mechanism between non-genomic and genomic modes of estrogens.

scientific article published on 11 July 2005

Cavity depth and width effects on cyclophane-steroid recognition: molecular complexation of cholesterol and progesterone in aqueous solution.

scientific article published on March 1995

Chemico-genetic identification of drebrin as a regulator of calcium responses

scientific article

Control of gene expression with small molecules: biotin-mediated acylation of targeted lysine residues in recombinant yeast

scientific article

Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9 ⬇️

scientific article published on July 24, 2013

Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores

scientific article published on 27 March 2014

Development of a cell-based, high-throughput screening assay for cholesterol efflux using a fluorescent mimic of cholesterol

scientific article

Efficient and Scalable Synthesis of 4-Carboxy-Pennsylvania Green Methyl Ester: A Hydrophobic Building Block for Fluorescent Molecular Probes

scientific article

Efficient delivery of streptavidin to mammalian cells: clathrin-mediated endocytosis regulated by a synthetic ligand

scientific article published in June 2002

Endocytic delivery of vancomycin mediated by a synthetic cell surface receptor: rescue of bacterially infected Mammalian cells and tissue targeting in vivo

scientific article published on January 2007

Facile synthesis of cids: biotinylated estrone oximes efficiently heterodimerize estrogen receptor and streptavidin proteins in yeast three hybrid systems

scientific article published in April 2004

Fluorescence-based cloning of a protein tyrosine kinase with a yeast tribrid system

scientific article published in August 2005

Fluorescent cellular sensors of steroid receptor ligands

scientific article published in September 2003

Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells.

scientific article

Human neutrophil peptides mediate endothelial-monocyte interaction, foam cell formation, and platelet activation.

scientific article published on 4 August 2011

Hydrophobic resorufamine derivatives: potent and selective red fluorescent probes of the endoplasmic reticulum of mammalian cells

scientific article published on 9 May 2016

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

scientific article published in February 2012

Interaction of 3β-amino-5-cholestene with phospholipids in binary and ternary bilayer membranes

scientific article published on 14 December 2011

Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.

scientific article

Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.

scientific article published on 8 August 2007

Molecule-specific imaging with mass spectrometry and a buckminsterfullerene probe: application to characterizing solid-phase synthesized combinatorial libraries

scientific article published on 01 March 2004

Multifunctional silane polymers for persistent surface derivatization and their antimicrobial properties.

scientific article published on 12 June 2008

Non-natural cell surface receptors: synthetic peptides capped with N-cholesterylglycine efficiently deliver proteins into Mammalian cells

scientific article published in January 2003

Novel acid-activated fluorophores reveal a dynamic wave of protons in the intestine of Caenorhabditis elegans

scientific article

Practical synthesis of 3beta-amino-5-cholestene and related 3beta-halides involving i-steroid and retro-i-steroid rearrangements

scientific article published on February 2009

Quantification of Small Molecule-Protein Interactions using FRET between Tryptophan and the Pacific Blue Fluorophore.

scientific article published on 19 December 2016

Rapid detection of protein tyrosine kinase activity in recombinant yeast expressing a universal substrate.

scientific article

Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide

scientific article published on 10 July 2008

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

scientific article

Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials

scientific article published in August 2006

Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity

scientific article published on 09 May 2019

Small-molecule triggers of tadpole metamorphosis.

scientific article published on October 2006

Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase

scientific article

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

scientific article published on 4 May 2011

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

scientific article

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

scientific article

Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.

scientific article published on 14 February 2011

Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells

scientific article published on 26 June 2015

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses

scientific article

Synthesis of a Fluorescent Analogue of Paclitaxel That Selectively Binds Microtubules and Sensitively Detects Efflux by P-Glycoprotein

scientific article

Synthesis of a beta-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and streptavidin proteins in a yeast three-hybrid system.

scientific article

Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays

scientific article published in October 2003

Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase

scientific article published on August 2007

Synthesis of an artificial cell surface receptor that enables oligohistidine affinity tags to function as metal-dependent cell-penetrating peptides

scientific article published on January 2006

Synthesis of chimeric 7alpha-substituted estradiol derivatives linked to cholesterol and cholesterylamine.

scientific article published in February 2002

Synthesis of fluorinated benzophenones, xanthones, acridones, and thioxanthones by iterative nucleophilic aromatic substitution

scientific article published on 23 November 2011

Synthetic cell surface receptors for delivery of therapeutics and probes ⬇️

scientific article published on February 25, 2012

Synthetic mimics of small Mammalian cell surface receptors

scientific article published in December 2004

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis

scientific article published on 05 September 2018

Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin Δ12-PGJ2 through Covalent Binding to Cys1438 ⬇️

scientific article published on December 16, 2011

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

scientific article published on 09 January 2020

The Pennsylvania Green Fluorophore: a hybrid of Oregon Green and Tokyo Green for the construction of hydrophobic and pH-insensitive molecular probes.

scientific article published on February 2006

The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency.

scientific article published on November 1998

List of works by Blake R. Peterson

11beta-alkyl-Delta9-19-nortestosterone derivatives: high-affinity ligands and potent partial agonists of the androgen receptor

A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity

A synthetic membrane-anchored antigen efficiently promotes uptake of antifluorescein antibodies and associated protein a by mammalian cells.

A synthetic mimic of human Fc receptors: defined chemical modification of cell surfaces enables efficient endocytic uptake of human immunoglobulin-G.

An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane

Analysis of protein tyrosine kinase inhibitors in recombinant yeast lacking the ERG6 gene

Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail

Antibody-Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome-Disruptive Peptide

Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics.

Augmenting vitamin D to combat genetic disease.

Calcium flux in neuroblastoma cells is a coupling mechanism between non-genomic and genomic modes of estrogens.

Cavity depth and width effects on cyclophane-steroid recognition: molecular complexation of cholesterol and progesterone in aqueous solution.

Chemico-genetic identification of drebrin as a regulator of calcium responses

Control of gene expression with small molecules: biotin-mediated acylation of targeted lysine residues in recombinant yeast

Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9 ⬇️

Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores

Development of a cell-based, high-throughput screening assay for cholesterol efflux using a fluorescent mimic of cholesterol

Efficient and Scalable Synthesis of 4-Carboxy-Pennsylvania Green Methyl Ester: A Hydrophobic Building Block for Fluorescent Molecular Probes

Efficient delivery of streptavidin to mammalian cells: clathrin-mediated endocytosis regulated by a synthetic ligand

Endocytic delivery of vancomycin mediated by a synthetic cell surface receptor: rescue of bacterially infected Mammalian cells and tissue targeting in vivo

Facile synthesis of cids: biotinylated estrone oximes efficiently heterodimerize estrogen receptor and streptavidin proteins in yeast three hybrid systems

Fluorescence-based cloning of a protein tyrosine kinase with a yeast tribrid system

Fluorescent cellular sensors of steroid receptor ligands

Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells.

Human neutrophil peptides mediate endothelial-monocyte interaction, foam cell formation, and platelet activation.

Hydrophobic resorufamine derivatives: potent and selective red fluorescent probes of the endoplasmic reticulum of mammalian cells

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

Interaction of 3β-amino-5-cholestene with phospholipids in binary and ternary bilayer membranes

Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.

Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.

Molecule-specific imaging with mass spectrometry and a buckminsterfullerene probe: application to characterizing solid-phase synthesized combinatorial libraries

Multifunctional silane polymers for persistent surface derivatization and their antimicrobial properties.

Non-natural cell surface receptors: synthetic peptides capped with N-cholesterylglycine efficiently deliver proteins into Mammalian cells

Novel acid-activated fluorophores reveal a dynamic wave of protons in the intestine of Caenorhabditis elegans

Practical synthesis of 3beta-amino-5-cholestene and related 3beta-halides involving i-steroid and retro-i-steroid rearrangements

Quantification of Small Molecule-Protein Interactions using FRET between Tryptophan and the Pacific Blue Fluorophore.

Rapid detection of protein tyrosine kinase activity in recombinant yeast expressing a universal substrate.

Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials

Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity

Small-molecule triggers of tadpole metamorphosis.

Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.

Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses

Synthesis of a Fluorescent Analogue of Paclitaxel That Selectively Binds Microtubules and Sensitively Detects Efflux by P-Glycoprotein

Synthesis of a beta-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and streptavidin proteins in a yeast three-hybrid system.

Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays

Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase

Synthesis of an artificial cell surface receptor that enables oligohistidine affinity tags to function as metal-dependent cell-penetrating peptides

Synthesis of chimeric 7alpha-substituted estradiol derivatives linked to cholesterol and cholesterylamine.

Synthesis of fluorinated benzophenones, xanthones, acridones, and thioxanthones by iterative nucleophilic aromatic substitution

Synthetic cell surface receptors for delivery of therapeutics and probes ⬇️

Synthetic mimics of small Mammalian cell surface receptors

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis

Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin Δ12-PGJ2 through Covalent Binding to Cys1438 ⬇️

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

The Pennsylvania Green Fluorophore: a hybrid of Oregon Green and Tokyo Green for the construction of hydrophobic and pH-insensitive molecular probes.

The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency.