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List of works by Ernst Wagner

2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event

scientific article

A Comprehensive Gene Expression Analysis of Resistance Formation upon Metronomic Cyclophosphamide Therapy

scientific article published in February 2013

A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential

scientific article published on 01 September 2007

A polyphosphoester conjugate of melphalan as antitumoral agent

scientific article

A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites

scientific article

A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry

scientific article published on 01 April 2000

Acetal linked oligoethylenimines for use as pH-sensitive gene carriers

scientific article

Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo.

scientific article

Acid-labile traceless click linker for protein transduction

scientific article published on 6 June 2012

Acrolein: unwanted side product or contribution to antiangiogenic properties of metronomic cyclophosphamide therapy?

scientific article published on 04 February 2008

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

scientific article

Adenoviral vectors coated with PAMAM dendrimer conjugates allow CAR independent virus uptake and targeting to the EGF receptor

scientific article

Adenovirus enhancement of transferrin-polylysine-mediated gene delivery ⬇️

scientific article published on October 1, 1991

Adenovirus-derived vectors for prostate cancer gene therapy

scientific article published on July 2010

Advances in cancer gene therapy: tumor-targeted delivery of therapeutic pDNA, siRNA, and dsRNA nucleic acids.

scientific article published on September 2007

Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding

scientific article

An RGD-oligolysine peptide: a prototype construct for integrin-mediated gene delivery

scientific article published on May 1998

An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes

scientific article

An acid sensitive ketal-based polyethylene glycol-oligoethylenimine copolymer mediates improved transfection efficiency at reduced toxicity

scientific article published on 27 August 2008

Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma

scientific article published on 10 May 2017

Anti‐angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives ⬇️

scientific article published on November 1, 2012

Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

scientific article published on November 2005

Application of membrane-active peptides for drug and gene delivery across cellular membranes

scientific article published in October 1998

Application of membrane-active peptides for nonviral gene delivery

scientific article published in August 1999

Artificial peptides for antitumoral siRNA delivery

scientific article published on 01 March 2020

Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions

scientific article

Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots

scientific article

Bid-induced release of AIF from mitochondria causes immediate neuronal cell death

scientific article

Biomaterials in RNAi therapeutics: quo vadis?

scientific article published on 10 May 2013

Bioreducible polycations as shuttles for therapeutic nucleic acid and protein transfection.

scientific article published on 08 January 2014

Bioresponsive polymers for nonviral gene delivery

scientific article published on April 2009

Bioresponsive polymers for the delivery of therapeutic nucleic acids.

scientific article published on January 2011

Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery

scientific article published on 21 February 2008

C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes

scientific article published in October 2005

Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts

scientific article

Capsomer-specific fluorescent labeling of adenoviral vector particles allows for detailed analysis of intracellular particle trafficking and the performance of bioresponsive bonds for vector capsid modifications

scientific article published on September 2010

Carbohydrate receptor-mediated gene transfer to human T leukaemic cells

article

Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury

scientific article published on 6 November 2008

Cell and tissue targeting of nucleic acids for cancer gene therapy

scientific article published on 27 March 2007

Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus

scientific article published in March 2000

Cellular dynamics of EGF receptor-targeted synthetic viruses.

scientific article published on 24 April 2007

Characterization and compatibility of hydroxyethyl starch-polyethylenimine copolymers for DNA delivery

scientific article

Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities

scientific article

Chemically Programmed Polymers for Targeted DNA and siRNA Transfection ⬇️

scientific article published on January 1, 2010

Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind

scholarly article by Daniel Müller et al published 8 August 1990 in Helvetica Chimica Acta

Click chemistry for high-density biofunctionalization of mesoporous silica

scientific article published on 29 August 2008

Clinical adenoviral gene therapy for prostate cancer

scientific article published on July 2010

Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells

scientific article published on 26 July 2019

Comb-like oligoaminoethane carriers: change in topology improves pDNA delivery

scientific article published on 6 January 2014

Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles

scientific article published on 13 May 2019

Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery

scientific article published on 30 July 2015

Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery

scientific article published on 3 January 2016

Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells

scientific article

Combined antitumoral effects of pretubulysin and methotrexate

Combining polyethylenimine and Fe(III) for mediating pDNA transfection

scientific article published on 19 February 2015

Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines

scientific article

Comparison of four different particle sizing methods for siRNA polyplex characterization

scientific article published on 16 October 2012

Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity

scientific article published on 22 December 2015

Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles

scientific article published on 02 September 2016

Controlled removal of a nonviral episomal vector from transfected cells

scientific article published on 16 July 2010

Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase.

scientific article published on 16 January 2012

Converging paths of viral and non-viral vector engineering

scientific article published in January 2008

Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface

scientific article published on 15 March 2019

Correction: EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice.

scientific article published on 28 August 2007

Correlation of length of linear oligo(ethanamino) amides with gene transfer and cytotoxicity

scientific article published on 6 February 2014

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes

scientific article published on July 1992

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

scientific article published on May 1997

Cryoconserved shielded and EGF receptor targeted DNA polyplexes: cellular mechanisms

scientific article published on 01 July 2005

DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization

scientific article published on March 2016

DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions

scientific article published on 8 July 2006

DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety

scientific article published in July 1991

DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression

scientific article published on January 2001

De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells

scientific article published on 27 June 2013

Decorated rods: a "bottom-up" self-assembly of monomolecular DNA complexes

scientific article published on 01 March 2006

Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing

scientific article

Defined polymeric materials for gene delivery

scientific article published on 05 February 2015

Degradable gene carriers based on oligomerized polyamines

scientific article

Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.

scientific article

Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides

scientific article published on 03 February 2020

Design and gene delivery activity of modified polyethylenimines.

scientific article

Development of a lyophilized plasmid/LPEI polyplex formulation with long-term stability--A step closer from promising technology to application

scientific article published on 9 January 2011

Developmental and cell cycle regulation of alfalfa nucMs1, a plant homolog of the yeast Nsr1 and mammalian nucleolin.

scientific article published on March 1996

Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo

scientific article published on July 2001

Different strategies for formation of pegylated EGF-conjugated PEI/DNA complexes for targeted gene delivery

scientific article

Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport

scientific article published in June 1999

Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes.

scientific article published in February 1993

Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR)-mediated delivery: a fully synthetic, EGFR-targeted gene transfer system avoiding receptor activation

scientific article published on 10 August 2011

Drug nanocarriers labeled with near-infrared-emitting quantum dots (quantoplexes): imaging fast dynamics of distribution in living animals

scientific article

Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.

scientific article published on 5 November 2015

Dual-targeted polyplexes based on sequence-defined peptide-PEG-oligoamino amides

scientific article published on 29 September 2014

Dual-targeted polyplexes: one step towards a synthetic virus for cancer gene therapy

scientific article published on 8 March 2011

Dynamics of photoinduced endosomal release of polyplexes

scientific article

EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery

scientific article published on 13 October 2016

EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

scientific article

EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent

scientific article published on 6 September 2017

EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene

scientific article published on 5 November 2013

EGFR-homing dsRNA activates cancer-targeted immune response and eliminates disseminated EGFR-overexpressing tumors in mice

scientific article

EUFEPS report. Contribution of academic research to discovery and development of medicines: current status and future opportunities

scientific article published on 01 February 2005

Effective incorporation of 2'-O-methyl-oligoribonucleotides into liposomes and enhanced cell association through modification with thiocholesterol

scientific article published on February 1992

Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: a potential therapeutic strategy for inhibition of tumor angiogenesis.

scientific article published on 16 November 2006

Effects of hypoxia and limited diffusion in tumor cell microenvironment on bystander effect of P450 prodrug therapy

scientific article published on 17 March 2006

Effects of membrane-active agents in gene delivery ⬇️

scientific article published on April 30, 1998

Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines

scientific article published on 20 June 2018

Efficient foreign gene expression in Epstein-Barr virus-transformed human B-cells

scientific article published in February 1994

Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.

scientific article published in March 1999

Efficient in vitro transfection of human keratinocytes with an adenovirus-enhanced receptor-mediated system

scientific article published on April 2000

Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

scientific article published on 21 May 2007

Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294.

scientific article published on 12 December 2012

Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery

scientific article published on 17 July 2018

Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene

scientific article

Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry

scientific article published on 27 April 2011

Evaluation of improved PAMAM-G5 conjugates for gene delivery targeted to the transferrin receptor

scientific article published on 22 May 2015

Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics

scientific article published on 24 December 2017

Extracellular targeting of synthetic therapeutic nucleic acid formulations

scientific article published on October 2008

Fast Characterization of Polyplexes by Taylor Dispersion Analysis

Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes.

scientific article

Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo

scientific article published on 19 March 2018

Formulation development of lyophilized, long-term stable siRNA/oligoaminoamide polyplexes

scientific article

Functional analysis of genomic DNA, cDNA, and nucleotide sequence of the mature C-type natriuretic peptide gene in vascular cells

scientific article published on July 2004

Functional maturation of dendritic cells by exposure to CD40L transgenic tumor cells, fibroblasts or keratinocytes

scientific article published in July 2001

Gelatin nanoparticles as a new and simple gene delivery system

scientific article published on 3 February 2005

Gene carriers based on hexanediol diacrylate linked oligoethylenimine: effect of chemical structure of polymer on biological properties

scientific article

Gene regulation by intracellular delivery and photodegradation of nanoparticles containing small interfering RNA.

scientific article published on 7 February 2014

Gene silencing and antitumoral effects of Eg5 or Ran siRNA oligoaminoamide polyplexes

scientific article published on 01 February 2014

Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate

scientific article published on January 1994

Gene therapy for advanced melanoma: selective targeting and therapeutic nucleic acids.

scientific article published on 25 March 2013

Gene therapy progress and prospects: synthetic polymer-based systems.

scientific article published on 05 June 2008

Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand

scientific article published in November 1992

Generation of a tumor- and tissue-specific episomal non-viral vector system

scientific article

Glutathione-sensitive RGD-poly(ethylene glycol)-SS-polyethylenimine for intracranial glioblastoma targeted gene delivery

scientific article published on August 2013

Glycerol and polylysine synergize in their ability to rupture vesicular membranes: a mechanism for increased transferrin-polylysine-mediated gene transfer

scientific article published on April 1997

High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes

scientific article published on April 1992

High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

scientific article published on July 1992

High-level expression of various apolipoprotein(a) isoforms by "transferrinfection": the role of kringle IV sequences in the extracellular association with low-density lipoprotein.

scientific article published on October 1994

Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma.

scientific article

Highly efficient siRNA delivery from core-shell mesoporous silica nanoparticles with multifunctional polymer caps

scientific article published on 28 January 2016

Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer

scientific article published on March 2015

How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides

scientific article published on 21 June 2016

Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery

scientific article published in November 2009

Hyperthermia-induced targeting of thermosensitive gene carriers to tumors

scientific article published in November 2008

Image-guided tumor-selective radioiodine therapy of liver cancer after systemic nonviral delivery of the sodium iodide symporter gene

scientific article published on 11 October 2011

Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery

scientific article

Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene

scientific article

Immunoadjuvant activity of interferon-gamma-liposomes co-administered with influenza vaccines

scientific article published on 01 March 2001

Immunotherapy of metastatic malignant melanoma by a vaccine consisting of autologous interleukin 2-transfected cancer cells: outcome of a phase I study

scientific article published on 01 April 1999

Impact of indium-111 oxine labelling on viability of human mesenchymal stem cells in vitro, and 3D cell-tracking using SPECT/CT in vivo

scientific article published on December 2011

Improved in vivo gene transfer into tumor tissue by stabilization of pseudodendritic oligoethylenimine-based polyplexes

scientific article

In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor.

scientific article published on 19 September 2014

In vitro and in vivo delivery of intact BAC DNA -- comparison of different methods

scientific article published in February 2004

In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer

scientific article published on February 1997

In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy

scientific article published on 25 February 2010

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice

scientific article

In vivo tracking of adipose tissue grafts with cadmium-telluride quantum dots

scientific article published on 5 March 2018

Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+ CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene

scientific article

Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway

scientific article published on 17 July 2006

Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran.

scientific article

Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles

scientific article published on 19 April 2017

Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles

scientific article published on June 1998

Influence of the molecular weight of bioreducible oligoethylenimine conjugates on the polyplex transfection properties

scientific article published on 6 June 2009

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle ⬇️

scientific article published on September 1, 1992

Interleukin-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumors in mice

scientific article published on 01 June 2000

Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells

scientific article published on 31 October 2016

Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery.

scientific article published on 26 June 2017

Liposomes as cytokine-supplement in tumor cell-based vaccines

scientific article published on 01 June 1999

Liposomes containing interferon-gamma as adjuvant in tumor cell vaccines

scientific article published on 01 January 2000

Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing

scientific article

Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

scientific article

Lymphocyte apoptosis: induction by gene transfer techniques

scientific article

Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells

scientific article

Mannose receptor-mediated gene delivery into antigen presenting dendritic cells.

scientific article

Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes

scientific article published on 20 March 2006

Membrane destabilization for improved cystolic delivery

scientific article published on 01 August 1999

Mesenchymal stem cell-mediated, tumor stroma-targeted radioiodine therapy of metastatic colon cancer using the sodium iodide symporter as theranostic gene

scientific article

MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators

scientific article published on 18 October 2018

Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles.

scientific article

Minicircle versus plasmid DNA delivery by receptor-targeted polyplexes

scientific article

Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods

scientific article

Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy

scientific article published on 6 September 2009

Monomolecular assembly of siRNA and poly(ethylene glycol)-peptide copolymers.

scientific article published on 26 January 2008

Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery

scientific article published on January 2011

Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal-Organic Frameworks.

scientific article published on 11 January 2017

Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery

NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development

scientific article published in 2021

Nanoparticle Technology: Having Impact, but Needing Further Optimization.

scientific article published on 16 June 2017

Nanoparticles bearing polyethyleneglycol-coupled transferrin as gene carriers: preparation and in vitro evaluation

scientific article

Nanosized multifunctional polyplexes for receptor-mediated siRNA delivery

scientific article published on 07 June 2012

Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers.

scientific article

New sequence-defined polyaminoamides with tailored endosomolytic properties for plasmid DNA delivery

scientific article published on 25 May 2012

Nitric oxide--a novel therapeutic for cancer.

scientific article published on 29 April 2008

Nomenclature for synthetic gene delivery systems

scientific article

Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization

scientific article published on 18 September 2020

Non-viral approaches to gene therapy.

scientific article published on December 1993

Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA).

scientific article published on May 2003

Novel Fmoc-polyamino acids for solid-phase synthesis of defined polyamidoamines

scientific article published on 04 March 2011

Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors.

scientific article published on 9 January 2018

Novel biocompatible cationic copolymers based on polyaspartylhydrazide being potent as gene vector on tumor cells

scientific article

Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers

scientific article published on July 2002

Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer

scientific article published on 25 October 2007

Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer

scientific article published in January 2003

Nucleic Acid-Based Approaches for Tumor Therapy

scientific article published on 09 September 2020

Nucleic acid carriers based on precise polymer conjugates

scientific article published on 22 July 2011

Nucleic acid-based therapeutics for glioblastoma

scientific article published on October 2011

Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery

scientific article published on 10 September 2008

Opening of size-selective pores in endosomes during human rhinovirus serotype 2 in vivo uncoating monitored by single-organelle flow analysis

scientific article published on January 2005

Optical imaging of transferrin targeted PEI/DNA complexes in living subjects

scientific article published in May 2003

Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers

scientific article

Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells under in vitro conditions

scientific article published on February 2006

Optimizing targeted gene delivery: chemical modification of viral vectors and synthesis of artificial virus vector systems

scientific article

Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation

scientific article published in January 2002

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

scientific article published on April 1999

Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles

scientific article published on 02 June 2020

Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene

scientific article published on 01 April 1997

Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes

scientific article

Photochemical internalization (PCI): a technology for drug delivery.

scientific article published on January 2010

Photochemical internalization of transgenes controlled by the heat-shock protein 70 promoter

scientific article published on May 2006

Photochemical internalization: a new tool for drug delivery.

scientific article published on December 2007

Photochemically enhanced gene delivery of EGF receptor-targeted DNA polyplexes

scientific article

Poly(I:C)-mediated tumor growth suppression in EGF-receptor overexpressing tumors using EGF-polyethylene glycol-linear polyethylenimine as carrier

scientific article published on 6 August 2010

PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors

scientific article published on 23 February 2012

Polycation-based DNA complexes for tumor-targeted gene delivery in vivo

scientific article published in March 1999

Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

scientific article

Polyhydroxyethylaspartamide-spermine copolymers: efficient vectors for gene delivery

scientific article

Polylysine-based transfection systems utilizing receptor-mediated delivery

scientific article published on 01 March 1998

Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions

scientific article published on 20 September 2019

Polymers for nucleic acid transfer-an overview.

scientific article

Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise ⬇️

scientific article published on December 22, 2011

Polyplex Evolution: Understanding Biology, Optimizing Performance

scientific article published on 5 March 2017

Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery

scientific article published on 13 May 2016

Potent retro-inverso D-peptide for simultaneous targeting of angiogenic blood vasculature and tumor cells

scientific article published on 2 January 2013

Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes

scientific article published on 12 October 2018

Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes

scientific article published on 13 October 2016

Pretubulysin: a new option for the treatment of metastatic cancer

scientific article

Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters).

scientific article

Proteomic analysis reveals differences in protein expression in spheroid versus monolayer cultures of low-passage colon carcinoma cells

scientific article

Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid

scientific article published on November 1994

Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

scientific article

Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding

scientific article

Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytes

scientific article published on January 2003

Recent developments in the application of plasmid DNA-based vectors and small interfering RNA therapeutics for cancer

scientific article published on November 2006

Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex.

scientific article published in June 1995

Regulation of the Tissue Factor Promoter in Endothelial Cells

scientific article published in Journal of Biological Chemistry

Reintroducing the sodium iodide symporter (NIS) to anaplastic thyroid carcinoma

scientific article published on 15 October 2017

Retro-inverso CendR peptide-mediated polyethyleneimine for intracranial glioblastoma-targeting gene therapy

scientific article published on 7 February 2014

Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration

scientific article

Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases

scientific article published on 07 July 2016

Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration

scientific article published on 27 January 2014

Self-assembled amphiphilic sequence-defined PEGylated three-arm oligo(ethanamino)amides via NCL reaction for drug delivery: Impact of building blocks on controlled release

scientific article published on 19 August 2015

Sequence defined disulfide-linked shuttle for strongly enhanced intracellular protein delivery

scientific article published on 19 November 2012

Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene

scientific article published on 9 May 2016

Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy

scientific article

Sequence-defined oligoaminoamides for the delivery of siRNAs.

scientific article published on January 2015

Sequence-defined polymers for the delivery of oligonucleotides

scientific article published on December 2014

Sequence-defined shuttles for targeted nucleic acid and protein delivery

scientific article

Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells

scientific article

Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity.

scientific article

Solid-phase supported design of carriers for therapeutic nucleic acid delivery

scientific article published on 29 September 2017

Solid-phase synthesis of sequence-defined T-, i-, and U-shape polymers for pDNA and siRNA delivery

scientific article

Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery

scientific article

Somatic gene therapy for cancer: the utility of transferrinfection in generating 'tumor vaccines'.

scientific article

Somatic gene transfer into the lactating ovine mammary gland

scientific article

Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery

scientific article published on 20 April 2016

Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice

scientific article published in November 2002

Specific targets in tumor tissue for the delivery of therapeutic genes

scientific article

Stability and activity of hydroxyethyl starch-coated polyplexes in frozen solutions or lyophilizates

scientific article published on 13 April 2014

Stabilization of gene delivery systems by freeze-drying

article

Stabilization of polyplexes via polymer crosslinking for efficient siRNA delivery

scientific article

Stabilized nonviral formulations for the delivery of MCP-1 gene into cells of the vasculoendothelial system

scientific article

Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes

scientific article published on 28 November 2012

Stromal targeting of sodium iodide symporter using mesenchymal stem cells allows enhanced imaging and therapy of hepatocellular carcinoma

scientific article published on March 2013

Structure-activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides

scientific article

Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations

scientific article published on July 2011

Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes

scientific article published on September 1994

Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

scientific article published on May 2009

Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery.

scientific article published on 3 May 2007

Synthesis of core-shell graphitic carbon@silica nanospheres with dual-ordered mesopores for cancer-targeted photothermochemotherapy

scientific article

Synthesis of linear polyethylenimine and use in transfection

scientific article published on 01 February 2012

Synthesis of polyethylenimine-based nanocarriers for systemic tumor targeting of nucleic acids

scientific article published in January 2013

Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes

scientific article

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia

scientific article

Systemic TNFα gene therapy synergizes with liposomal doxorubicine in the treatment of metastatic cancer

scientific article published on 13 November 2012

Systemic image-guided liver cancer radiovirotherapy using dendrimer-coated adenovirus encoding the sodium iodide symporter as theranostic gene

scientific article published on 10 July 2013

Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes

scientific article published on 19 April 2017

Targeted nucleic acid delivery into tumors: new avenues for cancer therapy

scientific article published on April 2004

Targeted radioiodine therapy of neuroblastoma tumors following systemic nonviral delivery of the sodium iodide symporter gene

scientific article published on 29 September 2009

Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell

scientific article published on 24 April 2016

Targeting of polyplexes: toward synthetic virus vector systems

scientific article

Targeting tumors with non-viral gene delivery systems.

scientific article

Technology evaluation: TNFerade, GenVec.

scientific article published on August 2003

Temperature dependent gene expression induced by PNIPAM-based copolymers: potential of hyperthermia in gene transfer

scientific article published on May 2006

Ten-year anniversary of Current Opinion in Molecular Therapeutics: a decade of experience in molecular therapeutics - progress, setbacks and surprises.

scientific article

Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo.

scientific article published on 11 November 2009

The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.

scientific article

The actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility

scientific article (publication date: 2014)

The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes.

scientific article published on 11 January 2013

The establishment of an up-scaled micro-mixer method allows the standardized and reproducible preparation of well-defined plasmid/LPEI polyplexes

scientific article published on 20 November 2010

The impact of carboxyalkylation of branched polyethylenimine on effectiveness in small interfering RNA delivery

scientific article published on September 2010

The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type

scientific article published on 15 September 2006

The proto-oncogene KRAS is targeted by miR-200c

scientific article published on January 2014

The silent (R)evolution of polymeric nucleic acid therapeutics

scientific article published on 05 August 2008

The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells

scientific article published on October 1998

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

scientific article published on 9 December 2013

The transport of nanosized gene carriers unraveled by live-cell imaging

scientific article published on February 2006

Therapeutic plasmid DNA versus siRNA delivery: common and different tasks for synthetic carriers

scientific article

Tissue-dependent factors affect gene delivery to tumors in vivo

scientific article published in July 2003

To be targeted: is the magic bullet concept a viable option for synthetic nucleic acid therapeutics?

scientific article published on 17 June 2011

Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains

scientific article

Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo

scientific article

Transcriptionally targeted nonviral gene transfer using a beta-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells

scientific article published in January 2007

Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycol

scientific article published on March 2001

Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycol

scholarly article by Markus D�chler published in January 2001

Transferrinfection: a highly efficient way to express gene constructs in eukaryotic cells

scientific article published on October 1992

Tumor targeting with surface-shielded ligand--polycation DNA complexes.

scientific article published in May 2001

Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity

scientific article

Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment

scientific article

Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes

scientific article published in August 2003

Tumor-targeted gene transfer with DNA polyplexes

scientific article

Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes

scientific article published on 7 June 2016

Tuning nanoparticle uptake: live-cell imaging reveals two distinct endocytosis mechanisms mediated by natural and artificial EGFR targeting ligand

scientific article published on 5 June 2012

Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes

scientific article

V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo

scientific article published on 14 November 2013

V-ATPase inhibition regulates anoikis resistance and metastasis of cancer cells.

scientific article published on 30 January 2014

Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2

scientific article published on October 1995

Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomes

scientific article published in December 2000

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression

scientific article

pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing

scientific article published on 11 December 2015

pH-responsive release of acetal-linked melittin from SBA-15 mesoporous silica

scientific article published on 17 June 2011

pH-responsive shielding of non-viral gene vectors.

scientific article published on September 2006

siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.

scientific article published on March 2007

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