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List of works by Maria Filomena Botelho

2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: photosensitization efficiency, subcellular localization and in vivo studies.

scientific article published on 19 June 2012

533 Evaluation of the role of mir-34b in modulation of radioresistance in non-small-cell lung cancer

99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation

scientific article

A (99m)Tc(CO)(3)-labeled pyrazolyl-alpha-melanocyte-stimulating hormone analog conjugate for melanoma targeting

scientific article published on 19 November 2007

A cross-sectional analysis of patient characteristics, health conditions and patient experience at a Portuguese medical acupuncture teaching appointment

scientific article published on 01 November 2019

A new therapeutic proposal for inoperable osteosarcoma: Photodynamic therapy

scientific article published on 21 November 2017

A novel model of distal colon cancer in athymic mice

article

Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target

scientific article published on 28 July 2020

Advances on photodynamic therapy of melanoma through novel ring-fused 5,15-diphenylchlorins

scientific article published on 4 January 2018

Amniotic membrane extract differentially regulates human peripheral blood T cell subsets, monocyte subpopulations and myeloid dendritic cells

scientific article published on 26 March 2018

Amniotic membrane: from structure and functions to clinical applications.

scientific article published on 18 May 2012

An Overview on Radiation Sensitivity in Hereditary Breast and Ovarian Cancer Syndrome

scientific article published on 02 July 2022

An insight into tumoral hypoxia: the radiomarkers and clinical applications

Apical Sealing Ability of Two Calcium Silicate-Based Sealers Using a Radioactive Isotope Method: An In Vitro Apexification Model

scientific article published in 2021

Ascorbic Acid Chemosensitizes Colorectal Cancer Cells and Synergistically Inhibits Tumor Growth

scientific article published on 23 July 2018

Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile

scientific article published on 06 April 2016

Beyond the limits of oxygen: effects of hypoxia in a hormone-independent prostate cancer cell line.

scientific article published on 12 September 2013

Biodentine Boosts, WhiteProRootMTA Increases and Life Suppresses Odontoblast Activity

scientific article published on 11 April 2019

Bisphosphonate-related osteonecrosis of the jaw: specificities

scientific article published on 23 September 2014

Brain blood flow SPET imaging in heroin abusers

scientific article published in August 2006

Butyrate, a dietary fiber derivative that improves irinotecan effect in colon cancer cells

scientific article published on 3 March 2018

Calcium Phosphate Ceramics Can Prevent Bisphosphonate-Related Osteonecrosis of the Jaw

scientific article published on 22 April 2020

Can the regenerative potential of an alkali-free bioactive glass composition be enhanced when mixed with resorbable β-TCP?

article

Cardiac lymphatic dynamics after ischemia and reperfusion—experimental model

scientific article published on 01 October 1998

Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties.

scientific article published on 30 November 2012

Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: novel antitumor DNA monoalkylating agents.

scientific article published on 23 July 2010

Cholangiocarcinoma: from molecular biology to treatment

scientific article published on October 2015

ClearPEM scanners: Performance results and studies in preclinical environment

Clinical translation for endometrial cancer stem cells hypothesis

scientific article published on 30 July 2015

Combined dual effect of modulation of human neutrophils' oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives

scientific article published on 30 May 2016

Comparison of the predicted in vivo behaviour of the Sn(II)-APDDMP complex and the results as studied in a rodent model.

scientific article published in September 2004

Cytotoxic Effects of Zoom® Whitening Product in Human Fibroblasts

scientific article published on 25 March 2020

Cytotoxic effects of a chlorhexidine mouthwash and of an enzymatic mouthwash on human gingival fibroblasts

scientific article published on 17 October 2019

Cytotoxicity of ascorbic acid in a human colorectal adenocarcinoma cell line (WiDr): in vitro and in vivo studies.

scientific article published on 13 September 2012

Deep lung--cellular reaction to HIV

scientific article

Dental caries and bacterial load in saliva and dental biofilm of type 1 diabetics on continuous subcutaneous insulin infusion.

scientific article

Dental caries, diabetes mellitus, metabolic control and diabetes duration: A systematic review and meta-analysis

scientific article published on 08 January 2020

Diabetes mellitus and prostate cancer metabolism: Is there a relationship?

scientific article published on 30 September 2018

Dibrominated camphoric acid derived salen complexes: Synthesis, characterization and cytotoxic activity

Direct Pulp Capping: What is the Most Effective Therapy?—Systematic Review and Meta-Analysis

scientific article published on 15 February 2018

Direct Pulp Capping: Which is the Most Effective Biomaterial? A Retrospective Clinical Study

scientific article published on 16 October 2019

Doping β-TCP as a Strategy for Enhancing the Regenerative Potential of Composite β-TCP-Alkali-Free Bioactive Glass Bone Grafts. Experimental Study in Rats

scientific article published on 20 December 2018

Drug transporters play a key role in the complex process of Imatinib resistance in vitro.

scientific article published on 23 December 2014

Effect of Different Irrigation Solutions on the Diffusion of MTA Cement into the Root Canal Dentin

scientific article published on 01 December 2020

Effect of amniotic membrane proteins in human cancer cell lines: an exploratory study.

scientific article published on 28 February 2014

Effect of miR-34b overexpression on the radiosensitivity of non-small cell lung cancer cell lines.

scientific article published on May 2012

Effects of X-radiation on lung cancer cells: the interplay between oxidative stress and P53 levels

scientific article published on 18 November 2015

Efflux Pumps Modulation in Colorectal Adenocarcinoma Cell Lines: The Role of Nuclear Medicine

Endometrial Cancer Spheres Show Cancer Stem Cells Phenotype and Preference for Oxidative Metabolism

scientific article published on 29 November 2018

Epithelial-mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer

Evaluation of Prognostic Factors of Severity in Acute Biliary Pancreatitis

scientific article published on 16 June 2020

Evaluation of a (99m) Tc-labelled meso-bisphenylporphyrin as a tumour image agent

scientific article published on 7 February 2014

Evaluation of dentin formed in autogenous tooth transplantation in the dog: a comparison between one- and two-stage surgical techniques.

scientific article

Evaluation of dentinogenesis inducer biomaterials: an in vivo study

scientific article published on 28 November 2019

Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis

scientific article published on 12 July 2019

First pass evaluation of blood velocity in the pulmonary artery

scientific article published in July 2001

Fluorine-18 Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression

scientific article published on 3 June 2015

Functional Impairment of Circulating FcεRI+ Monocytes and Myeloid Dendritic Cells in Hepatocellular Carcinoma and Cholangiocarcinoma Patients

scientific article published on 04 March 2019

Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma

scientific article published on 16 August 2019

Functional hepatocellular regeneration in elderly patients undergoing hepatectomy

scientific article published on 09 January 2014

Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi

scientific article published on June 2007

Glycolysis Inhibition as a Strategy for Hepatocellular Carcinoma Treatment?

scientific article published on 01 January 2019

GuttaFlow® Bioseal Cytotoxicity Assessment: In Vitro Study

scientific article published on 19 September 2020

Halogen atom effect on photophysical and photodynamic characteristics of derivatives of 5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin.

scientific article

Hepatectomy and liver regeneration: from experimental research to clinical application

scientific article published on 8 May 2013

Hepatic extraction fraction: interest of its quantification in patients with hepatic tumours

scientific article published on 01 July 2012

Hepatocellular carcinoma and chemotherapy: the role of p53.

scientific article published on 21 December 2012

Hepatocellular carcinoma: epidemiology, biology, diagnosis, and therapies

scientific article

Histologic evaluation of the effect of mineral trioxide aggregate-Fillapex as a root canal sealer in rat teeth submitted to late replantation

scientific article published on January 2017

Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability.

scientific article

Hypoxia-induced redox alterations and their correlation with 99mTc-MIBI and 99mTc-HL-91 uptake in colon cancer cells

scientific article

Iberian atmospheric dynamics and large forest fires in mainland Portugal

article

Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viability

scientific article published on 11 October 2016

In vitro photodynamic activity of 5,15-bis(3-hydroxyphenyl)porphyrin and its halogenated derivatives against cancer cells

scientific article

In vivo biodistribution of antihyperglycemic biopolymer-based nanoparticles for the treatment of type 1 and type 2 diabetes.

scientific article published on 19 December 2016

Influence of Aldehyde Dehydrogenase Inhibition on Stemness of Endometrial Cancer Stem Cells

scientific article published in 2024

Influence of P53 on the radiotherapy response of hepatocellular carcinoma.

scientific article published on 30 September 2015

Influence of normal mammary epithelium on breast cancer progression: the protective role of early pregnancy

scientific article published in November 2010

Intermittent Pringle Maneuver and Hepatic Function: Perioperative Monitoring by Noninvasive ICG-Clearance

scientific article published on 01 December 2009

Intestinal Epithelial Stem Cells: Distinct Behavior After Surgical Injury and Teduglutide Administration.

scientific article

Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in rats

scientific article

Kinetics and dynamic evaluation of specific immunotherapy

scientific article published on 01 December 2004

Lipoic Acid Prevents High-Fat Diet-Induced Hepatic Steatosis in Goto Kakizaki Rats by Reducing Oxidative Stress Through Nrf2 Activation

scientific article published on 11 September 2018

Liver diseases: what is known so far about the therapy with human amniotic membrane?

scientific article

Lung cancer: the immune system and radiation.

scientific article published on January 2015

Lymphatic uptake of pulmonary delivered radiolabelled solid lipid nanoparticles

scientific article published in December 2002

MIA PaCa-2 and PANC-1 - pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors

scientific article published on 17 February 2016

Magnetic resonance spectroscopy in cancer diagnostics

Mammospheres of hormonal receptor positive breast cancer diverge to triple-negative phenotype.

scientific article published on 25 November 2017

Metabolic effects of hypoxia in colorectal cancer by 13C NMR isotopomer analysis

scientific article

Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and β-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats

scientific article published on 11 December 2013

Midterm follow-up of esophageal anastomosis for esophageal atresia repair: long-gap versus non-long-gap

scientific article published on 01 January 2007

Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies

scientific article published on October 2006

Multifactorial Scores and Biomarkers of Prognosis of Acute Pancreatitis: Applications to Research and Practice

scientific article published on 04 January 2020

Murine Models of Acute Pancreatitis: A Critical Appraisal of Clinical Relevance

scientific article published on 07 June 2019

Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática profunda pulmonar

scientific article published on 01 January 2010

New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin.

scientific article published on 04 March 2016

New estradiol based 111In complex towards the estrogen receptor

Novel 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine fused chlorins as very active photodynamic agents for melanoma cells.

scientific article published on 2 September 2015

Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug Resistance Proteins: Targets of Human Amniotic Membrane in Hepatocellular Carcinoma

scientific article published on 10 March 2016

P-glycoprotein versus MRP1 on transport kinetics of cationic lipophilic substrates: a comparative study using [99mTc]sestamibi and [99mTc]tetrofosmin

scientific article published on April 2009

Perioperative tumor cell dissemination in patients with primary or metastatic colorectal cancer.

scientific article published on 31 July 2009

Platinum(II) Ring-Fused Chlorins as Near-Infrared Emitting Oxygen Sensors and Photodynamic Agents.

scientific article published on 22 February 2017

Portal Venous Pressure Variation during Hepatectomy: A Prospective Study

scientific article published on 01 June 2019

Positron emission tomography diagnostic imaging in multidrug-resistant hepatocellular carcinoma: focus on 2-deoxy-2-(18F)Fluoro-D-Glucose

scientific article published on October 2014

Quantitative scintigraphic analysis of pulp revascularization in autotransplanted teeth in dogs

scientific article published on 25 August 2010

Quercetin in Cancer Treatment, Alone or in Combination with Conventional Therapeutics?

scientific article published on 12 August 2015

Radioiodinated ligands for the estrogen receptor: effect of different 7-cyanoalkyl chains on the binding affinity of novel iodovinyl-6-dehydroestradiols

scientific article

Radiolabelling of ascorbic acid: a new clue to clarify its action as an anticancer agent?

scientific article published on April 2012

Radiopharmaceuticals for Bone Metastasis Therapy and Beyond: A Voyage from the Past to the Present and a Look to the Future ⬇️

scientific article published on October 17, 2012

Radiotracers in Oncology ⬇️

scientific article published on April 1, 2012

Retinoblastoma: might photodynamic therapy be an option?

scientific article published on 13 January 2015

Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment.

scientific article published on 30 July 2015

Revisiting colorectal cancer animal model – An improved metastatic model for distal rectosigmoid colon carcinoma

article

Ring-Fused Diphenylchlorins as Potent Photosensitizers for Photodynamic Therapy Applications: In Vitro Tumor Cell Biology and in Vivo Chick Embryo Chorioallantoic Membrane Studies

scientific article published on 09 October 2019

Sealing efficacy of system B versus Thermafil and Guttacore obturation techniques evidenced by scintigraphic analysis

scientific article published on January 2017

Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma.

scientific article published on 27 October 2015

Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells

scientific article published in Scientific Reports

Study of perioperative liver function by dynamic monitoring of ICG-clearance.

scientific article

Synthesis and biodistribution studies of two novel radioiodinated areno-annelated estra-1,3,5(10),16-tetraene-3-ols as promising estrogen receptor radioligands

Synthesis and biological evaluation of new naphthoquinone-containing pyrrolo-thiazoles as anticancer agents

Synthesis of new 2-galactosylthiazolidine-4-carboxylic acid amides. Antitumor evaluation against melanoma and breast cancer cells

scientific article published on 13 April 2012

Synthesis, characterization and assessment of the cytotoxic activity of Cu(II), Fe(III) and Mn(III) complexes of camphoric acid-derived salen ligands

article published in 2015

Synthetic Calcium Phosphate Ceramics as a Potential Treatment for Bisphosphonate-Related Osteonecrosis of the Jaw

scientific article published on 06 June 2019

Targeting Hepatocellular Carcinoma: What did we Discover so Far?

scientific article

Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles.

scientific article published on 4 April 2014

Teduglutide effects on gene regulation of fibrogenesis on an animal model of intestinal anastomosis

scientific article published on 4 May 2017

The importance of radiotherapy on diffuse large B cell lymphoma treatment: a current review.

scientific article published on 13 August 2015

The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation.

scientific article published on 08 February 2016

The role of vitamins in cancer: a review

scientific article published on January 2011

Tumor Resection Induces Alterations on Serum Phospholipidome of Liver Cancer Patients

scientific article published on 11 February 2020

Tumour functional imaging by PET

scientific article published on 05 February 2020

Ventilation and perfusion display in a single image

scientific article published on 01 January 1991

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