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List of works by Claudio Arra

A mouse model demonstrates a multigenic origin of congenital hypothyroidism

scientific journal article

A mouse model for hereditary thyroid dysgenesis and cleft palate

scientific journal article

A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice

scientific article published on 24 February 2016

A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration

scientific article published on 23 April 2009

A urokinase receptor-derived peptide inhibiting VEGF-dependent directional migration and vascular sprouting

scientific article

Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in mice

scientific article

An overview of loco-regional treatments in patients and mouse models for hepatocellular carcinoma.

scientific article

Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking.

scientific article

Antitumor activity of PEGylated biodegradable nanoparticles for sustained release of docetaxel in triple-negative breast cancer

scientific article

B cells contribute to the antitumor activity of CpG-oligodeoxynucleotide in a mouse model of metastatic lung carcinoma.

scientific article

BAG3 controls angiogenesis through regulation of ERK phosphorylation.

scientific article published on 6 February 2012

BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein

scientific article

BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

scientific article

Biodegradable core-shell nanoassemblies for the delivery of docetaxel and Zn(II)-phthalocyanine inspired by combination therapy for cancer

scientific article

Biodegradable nanoparticles bearing amine groups as a strategy to alter surface features, biological identity and accumulation in a lung metastasis model

scientific article published on 05 September 2018

CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation

scientific article

CBX7 is a tumor suppressor in mice and humans

scientific article

CBX7 is a tumor suppressor in mice and humans

CRIPTO-1: a novel target for therapeutic intervention in human carcinoma

scientific article published on October 2004

CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis.

scientific article published on 17 March 2016

CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy

scientific article

Cancer-associated CD43 glycoforms as target of immunotherapy.

scientific article

Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity.

scientific article published on June 2015

Characterization of HMGA1P6 transgenic mouse embryonic fibroblasts

scientific article published on 13 August 2020

Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo

scientific article

Circadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells.

scientific article published on May 2010

Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors.

scientific article published on 27 September 2011

Core-shell biodegradable nanoassemblies for the passive targeting of docetaxel: features, antiproliferative activity and in vivo toxicity

scientific article

CpG-ODN increases the release of VEGF in a mouse model of lung carcinoma

scientific article published on 08 October 2010

Cripto haploinsufficiency affects in vivo colon tumor development

scientific article

Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells

scientific article published on January 2004

Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer.

scientific article published on 10 November 2013

Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis

scientific article

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge.

scientific article published on 04 January 2012

Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer

scientific article published on 17 May 2019

Differential prepuberal handling modifies behaviour and excitatory amino acids in the forebrain of the Naples High-Excitability rats.

scientific article

Dissecting the role of curcumin in tumour growth and angiogenesis in mouse model of human breast cancer

scientific article

Dual Oncogenic/Anti-Oncogenic Role of PATZ1 in FRTL5 Rat Thyroid Cells Transformed by the Oncogene

article

Early identification of left ventricular dysfunction induced by trastuzumab

scientific article published on 01 December 2011

Effects of a human compact anti-ErbB2 antibody on prostate cancer.

scientific article

Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats.

scientific article

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene

scientific article published in March 2013

Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in Naples High Excitability rats.

scientific article published on 2 December 2013

Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug.

scientific article published on 12 November 2008

Exposure to 50 Hz electromagnetic field raises the levels of the anti-apoptotic protein BAG3 in melanoma cells

scientific article published on November 2011

Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice

retracted article

Gastrin and cholecystokinin peptide-based radiopharmaceuticals: an in vivo and in vitro comparison.

scientific article published on 24 February 2011

HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAs

scientific article

HMGA1-pseudogenes and cancer

scientific article

HMGA2 cooperates with either p27(kip1) deficiency or Cdk4(R24C) mutation in pituitary tumorigenesis.

scientific article published on 20 November 2017

HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity

scientific article

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice

scientific article published in March 2006

Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotype

scientific article

IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.

scientific article

Ibuprofen delivered by poly(lactic-co-glycolic acid) (PLGA) nanoparticles to human gastric cancer cells exerts antiproliferative activity at very low concentrations

scientific article

Identification of the genes up- and down-regulated by the high mobility group A1 (HMGA1) proteins: tissue specificity of the HMGA1-dependent gene regulation

scientific article published on August 2004

Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum.

scientific article published on 17 January 2015

Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice

scientific article

Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice

scientific article published on 4 March 2009

In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging.

scientific article published on February 2004

In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging

scientific article (publication date: March 2004)

In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with 99mTc-tricarbonyl

scientific article

In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder.

scientific article

Inhibition of stromal CXCR4 impairs development of lung metastases.

scientific article

Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth

scientific article

Inhibitory effect of (-)-epigallocatechin-3-gallate and bleomycin on human pancreatic cancer MiaPaca-2 cell growth

scientific article published on 29 July 2015

Interleukin 18: friend or foe in cancer

scientific article published on 08 October 2013

Intraluminal gel ultrasound and eco-color doppler: new tools for the study of colorectal cancer in mice

scientific article

Modulation of cell apoptosis by AIR

scientific article published on 19 July 2007

Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

scientific article published on August 1999

Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression

scientific article published on 3 May 2015

Mouse Models in Prostate Cancer Translational Research: From Xenograft to PDX

scientific article

NK1.1 cells and CD8 T cells mediate the antitumor activity of Cl-IB-MECA in a mouse melanoma model.

scientific article

New Adamantyl Chalcones: Synthesis, Antimicrobial and Anticancer Activities.

scientific article published on 24 August 2016

Novel metronomic chemotherapy and cancer vaccine combinatorial strategy for hepatocellular carcinoma in a mouse model

scientific article

PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration

scientific article published on March 2015

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas

scientific article published on August 2016

PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells

scientific article published on 29 April 2016

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation

scientific article published in 2014

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

scientific article

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.

scientific article published on 24 October 2013

Peptide modified nanocarriers for selective targeting of bombesin receptors.

scientific article published on 9 February 2010

Peptide-containing aggregates as selective nanocarriers for therapeutics.

scientific article published on April 2008

Plasmacytoid Dendritic Cells Alter the Antitumor Activity of CpG-Oligodeoxynucleotides in a Mouse Model of Lung Carcinoma

scientific article published on 20 September 2010

Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice

scientific article published on 25 January 2013

Plasmacytoids dendritic cells are a therapeutic target in anticancer immunity.

scientific article published on 09 May 2012

Polycomb protein family member CBX7 plays a critical role in cancer progression

scientific article (publication date: 2015)

Polyinosinic-polycytidylic acid limits tumor outgrowth in a mouse model of metastatic lung cancer.

scientific article published on 18 April 2012

Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases

scientific article

Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum

scientific article

Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.

scientific article

Prepuberal subchronic methylphenidate and atomoxetine induce different long-term effects on adult behaviour and forebrain dopamine, norepinephrine and serotonin in Naples high-excitability rats.

scientific article published on 13 February 2010

Prostate cancer detection in the "grey area" of prostate-specific antigen below 10 ng/ml: head-to-head comparison of the updated PCPT calculator and Chun's nomogram, two risk estimators incorporating prostate cancer antigen 3.

scientific article

Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction.

scientific article published in April 2014

Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system

scientific article published in May 1995

Retraction notice to “Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice” [Eur J Cancer 47 (2011) 470–478]

article

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

scientific article published on January 2010

Rhes is involved in striatal function

scientific journal article

Role of BAG3 protein in leukemia cell survival and response to therapy.

scientific article published on 15 June 2012

Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells

scientific article

SOM230, A New Somatostatin Analogue, Is Highly Effective in the Therapy of Growth Hormone/Prolactin-Secreting Pituitary Adenomas

scientific article published on 01 May 2007

Simultaneous blockage of different EGF-like growth factors results in efficient growth inhibition of human colon carcinoma xenografts.

scientific article

Single amino acid substitutions in the chemotactic sequence of urokinase receptor modulate cell migration and invasion

scientific article (publication date: 2012)

Strain Analysis in the Assessment of a Mouse Model of Cardiotoxicity due to Chemotherapy: Sample for Preclinical Research.

scientific article published in January 2016

Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis.

scientific article published on 25 August 2009

Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-alpha in head and neck cancer cells in vitro and in vivo

scientific article published in January 2006

Target-based agents in neoadjuvant treatment of liver metastases from colorectal cancer: secret weapons in anti-cancer war?

scientific article published on 24 September 2009

Targeting androgen receptor/Src complex impairs the aggressive phenotype of human fibrosarcoma cells

scientific article

The [Tc(N)(PNP)]2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: in vitro and in vivo studies

scientific article published on 01 April 2007

The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth

scientific article

The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.

scientific article published on 12 December 2006

The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias.

scientific article published on 9 December 2014

The emerging issue of cardiac dysfunction induced by antineoplastic angiogenesis inhibitors ⬇️

scientific article published on January 16, 2013

The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways

scientific article

The role of morphine in animal models of human cancer: does morphine promote or inhibit the tumor growth?

scientific article published on 28 August 2013

The soluble form of urokinase receptor promotes angiogenesis through its Ser⁸⁸-Arg-Ser-Arg-Tyr⁹² chemotactic sequence

scientific article published on 01 December 2010

The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo

scientific article published on 8 June 2015

The urokinase receptor-derived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells.

scientific article published on 13 June 2016

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

scientific article published in May 2005

Transient exposure to cytarabine increases peptide growth factor receptor expression and tumorigenicity of melanoma cells

scientific article published on 01 July 1997

Triple negative breast cancer: looking for the missing link between biology and treatments

scientific article

Tumour biomarkers: homeostasis as a novel prognostic indicator

scientific article

Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): at the cross-road of pancreatic cancer cell proliferation

scientific article published on December 2013

Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence.

scientific article

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase.

scientific article

β-hairpin peptide that targets vascular endothelial growth factor (VEGF) receptors: design, NMR characterization, and biological activity

scientific article

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