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List of works by Bernadette O Fernandez

A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome.

scientific article published on 19 February 2018

An integrated approach to assessing nitroso-redox balance in systemic inflammation

scientific article published on 14 June 2011

Application of an optimized total N-nitrosamine (TONO) assay to pools: placing N-nitrosodimethylamine (NDMA) determinations into perspective.

scientific article published in May 2010

Autologous transfusion of stored red blood cells increases pulmonary artery pressure.

scientific article

Beetroot juice versus chard gel: A pharmacokinetic and pharmacodynamic comparison of nitrate bioavailability.

scientific article published on 29 December 2016

Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial

scientific article published on 01 June 2019

Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury

scientific article published on October 2008

Changes in acute pulmonary vascular responsiveness to hypoxia during a progressive ascent to high altitude (5300 m).

scientific article published on 8 April 2017

Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissue

scientific article published on 11 November 2019

Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes

scientific article published on 21 November 2020

DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

scientific article published on 17 July 2015

Dermal Nitrite Application Enhances Global Nitric Oxide Availability: New Therapeutic Potential for Immunomodulation?

article

Design and conduct of 'Xtreme Alps': a double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude

scientific article

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart.

scientific article

Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition

scientific article

Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study.

scientific article published on 14 October 2017

Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude - A randomised controlled trial (Xtreme Alps)

scientific article published on 08 October 2019

Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation

scientific article

Endogenous H2S production deficiencies lead to impaired renal erythropoietin production

scientific article published on 20 November 2018

Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension.

scientific article published on 12 August 2016

Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms

scientific article published on 02 October 2009

Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase

scientific article published on 15 February 2017

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

scientific article published on 22 October 2009

Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

scientific article

Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release ⬇️

scientific article published on 27 December 2016

Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

scientific article published on 01 January 2020

Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway ⬇️

scientific article

Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.

scientific article

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling

scientific article published on 01 January 2020

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

scientific article

Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists

scientific article published on 26 January 2019

Mechanisms of ferriheme reduction by nitric oxide: nitrite and general base catalysis

scientific article published in August 2004

Mechanistic insights into nitrite-induced cardioprotection using an integrated metabolomic/proteomic approach.

scientific article published on 19 February 2009

Metabolic basis to Sherpa altitude adaptation

scientific article

Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis

scientific article published on 7 March 2008

N-Nitroso products from the reaction of indoles with Angeli's salt.

scientific article published on January 2006

Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

scientific article published on 22 December 2015

Nitrite catalyzes ferriheme protein reductive nitrosylation

scientific article published in September 2003

Nitrite catalyzes reductive nitrosylation of the water-soluble Ferri-Heme model FeIII(TPPS) to FeII(TPPS)(NO).

scientific article published in January 2003

Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues

scientific article published on 18 September 2005

Nitrosopersulfide (SSNO(-)) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

scientific article published on 11 January 2014

Nitrosopersulfide (SSNO-) targets soluble guanylyl cyclase and induces vasodilation in vivo

scientific article published on 2 September 2015

Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection.

scientific article published on 30 April 2018

On the chemical biology of the nitrite/sulfide interaction.

scientific article published on 23 December 2014

Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

scientific article published on 13 August 2018

Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?

scientific article published on 22 January 2019

Rapid free thiol rebound is a physiological response following cold-induced vasoconstriction in healthy humans, primary Raynaud and systemic sclerosis

scientific article published on 01 March 2019

Reactive Species Interactome Alterations in Oocyte Donation Pregnancies in the Absence and Presence of Pre-Eclampsia ⬇️

scientific article published on 06 March 2019

Redox-sensitivity and site-specificity of S- and N- denitrosation in proteins

scientific article

Short-term hypoxic vasodilation in vivo is mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

scientific article published on 06 January 2014

Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients.

scientific article published on 2 April 2015

Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-β1.

scientific article published on 17 February 2017

Suppression of erythropoiesis by dietary nitrate.

scientific article published on 24 November 2014

Systemic oxygen extraction during exercise at high altitude

scientific article

The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes.

scientific article published on 7 March 2018

The role of nitrogen oxides in human adaptation to hypoxia

scientific article published on 6 October 2011

Tissue processing of nitrite in hypoxia: an intricate interplay of nitric oxide-generating and -scavenging systems

scientific article published on 3 October 2008

Transfusion of blood stored for longer periods of time does not alter the reactive hyperemia index in healthy volunteers.

scientific article published on 20 March 2012

UVA Irradiation of Human Skin Vasodilates Arterial Vasculature and Lowers Blood Pressure Independently of Nitric Oxide Synthase

scientific article published on 20 January 2014

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