List of works - Anna M Rydzik

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.

scientific article published on 2 March 2017

19F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

scientific article published on 01 December 2019

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

scientific article published on August 2013

A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

scientific article published on 26 August 2011

Assay platform for clinically relevant metallo-β-lactamases ⬇️

scientific article published on 16 August 2013

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

scientific article

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles

scientific article

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase

article

Development and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylase

scientific article

Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase

scientific article published on 19 September 2014

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

scientific article published on February 2014

Interaction of Avibactam with Class B Metallo-β-Lactamases

scientific article

Modulating carnitine levels by targeting its biosynthesis pathway - selective inhibition of γ-butyrobetaine hydroxylase

scientific article published on May 2014

Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy

scientific article published on 24 February 2014

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

scientific article

Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids

scientific article (publication date: 6 October 2014)

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

scientific article

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

scientific article

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

scientific article

Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

scientific article published on 2 May 2016

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

scientific article published on 23 February 2018

Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA)

scientific article

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1†Electronic supplementary information (ESI) available: Procedures for protein expression and purification, 19F-labelling, crystallisation, data collection, and structure de

scientific article published on 4 November 2014

Synthesis and biochemical studies of tetraphosphate 5' mRNA cap analogs bearing bisphosphonate modification

scientific article

Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

scientific article published on 20 January 2012

Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹⁹F NMR studies.

scientific article published on 08 April 2015

Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5',5' bridge containing methylenebis(phosphonate) modification

scientific article published on 7 September 2009

Synthetic mRNA cap analogs with a modified triphosphate bridge – synthesis, applications and prospects

Use of ferrous iron by metallo-β-lactamases

scientific article

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation

scientific article published on 28 June 2017

List of works by Anna M Rydzik

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.

19F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

Assay platform for clinically relevant metallo-β-lactamases ⬇️

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase

Development and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylase

Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

Interaction of Avibactam with Class B Metallo-β-Lactamases

Modulating carnitine levels by targeting its biosynthesis pathway - selective inhibition of γ-butyrobetaine hydroxylase

Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA)

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1†Electronic supplementary information (ESI) available: Procedures for protein expression and purification, 19F-labelling, crystallisation, data collection, and structure de

Synthesis and biochemical studies of tetraphosphate 5' mRNA cap analogs bearing bisphosphonate modification

Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹⁹F NMR studies.

Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5',5' bridge containing methylenebis(phosphonate) modification

Synthetic mRNA cap analogs with a modified triphosphate bridge – synthesis, applications and prospects

Use of ferrous iron by metallo-β-lactamases

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation