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List of works by Roy Taylor

2-year remission of type 2 diabetes and pancreas morphology: a post-hoc analysis of the DiRECT open-label, cluster-randomised trial

scientific article published on 05 October 2020

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice

scientific article

Accelerating MR Imaging Liver Steatosis Measurement Using Combined Compressed Sensing and Parallel Imaging: A Quantitative Evaluation

scientific article published on 28 July 2015

Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production

scientific article published on 5 July 2005

Adenosine effects upon insulin action on lipolysis and glucose transport in human adipocytes

scientific article published on 01 March 1995

Adipocyte insulin binding and insulin action in chronic renal failure before and during continuous ambulatory peritoneal dialysis

scientific article

Altered volume, morphology and composition of the pancreas in type 2 diabetes

scientific article published on 7 May 2015

Beating type 2 diabetes into remission

scientific article published on 13 September 2017

Behaviour change during dietary Type 2 diabetes remission: a longitudinal qualitative evaluation of an intervention using a very low energy diet

scientific article published on 03 July 2019

Blood pressure and cardiovascular risk in the HOPE study

scientific article published in June 2002

Brief formula low-energy-diet for relapse management during weight loss maintenance in the Diabetes Remission Clinical Trial (DiRECT)

scientific article published on 06 January 2021

Calorie restriction and not glucagon-like peptide-1 explains the acute improvement in glucose control after gastric bypass in Type 2 diabetes

scientific article published on 2 September 2016

Calorie restriction and reversal of type 2 diabetes

scientific article published on 30 September 2016

Calorie restriction for long-term remission of type 2 diabetes

scientific article published on 01 January 2019

Can type 2 diabetes be reversed and how can this best be achieved? James Lind Alliance research priority number one

scientific article published on 03 December 2018

Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease

scientific article published on 22 November 2012

Cardiac structure and function are altered in type 2 diabetes and non-alcoholic fatty liver disease and associate with glycemic control

scientific article

Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study ⬇️

scientific article published on March 29, 2012

Catastrophic circulatory collapse following re-expansion pulmonary oedema

scientific article published on 01 June 1996

Causation of type 2 diabetes -- the Gordian knot unravels

scientific article published in February 2004

Chest pain of uncertain origin in patients admitted to a coronary care unit

scientific article published on 01 April 1982

Clinical Presentations of Diabetes

Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort

scientific article published on 30 November 2017

Cognitive impairment in primary biliary cirrhosis: symptom impact and potential etiology

scientific article published in August 2008

Conundrum of the HOPE study: Time of taking ramipril may account for lack of relation between blood pressure and outcome ⬇️

scientific article published on September 20, 2003

Correction: A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice.

scientific article published on 23 December 2008

Corrigendum: Calorie restriction for long-term remission of type 2 diabetes

scholarly article published in Clinical Medicine

Detecting diabetic retinopathy: Author's reply. ⬇️

scientific article published in January 1991

Dietary Intervention in Pregnant Women with Gestational Diabetes; Protocol for the DiGest Randomised Controlled Trial

scientific article published on 22 April 2020

Dietary and nutritional approaches for prevention and management of type 2 diabetes.

scientific article published on 13 June 2018

Dietary reversal of Type 2 diabetes motivated by research knowledge

scientific article published in June 2010

Diurnal variation in skeletal muscle and liver glycogen in humans with normal health and Type 2 diabetes

scientific article published in May 2015

Do obese but metabolically normal women differ in intra-abdominal fat and physical activity levels from those with the expected metabolic abnormalities? A cross-sectional study

scientific article

Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

scientific article published on 06 March 2019

Effect of physical activity on age-related changes in cardiac function and performance in women

scientific article published on 30 December 2014

Effect of repaglinide and gliclazide on postprandial control of endogenous glucose production

scientific article published in January 2005

Effect of vildagliptin on hepatic steatosis

scientific article

Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers.

scientific article published on 10 May 2017

Effects of raising muscle glycogen synthesis rate on skeletal muscle ATP turnover rate in type 2 diabetes.

scientific article published on 13 September 2011

Erratum. Very Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiological Changes in Responders and Nonresponders. Diabetes Care 2016;39:808-815.

scientific article published on 24 April 2018

Erratum: Dietary Intervention in Pregnant Women with Gestational Diabetes; Protocol for the DiGest Randomised Controlled Trial; Nutrients 2020, 12, 1165

scientific article published on 17 June 2020

Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial.

scientific article published on 10 August 2016

Gestational diabetes: emerging concepts in pathophysiology

scientific article published on 03 December 2010

Globus pallidus magnetization transfer ratio, T(1) and T(2) in primary biliary cirrhosis: relationship with disease stage and age.

scientific article published in April 2009

Glucose homoeostasis in chronic liver disease

scientific article

Hepatic Lipoprotein Export and Remission of Human Type 2 Diabetes after Weight Loss

scientific article published on 19 December 2019

Hepatic cholesteryl ester accumulation in lysosomal acid lipase deficiency: Non-invasive identification and treatment monitoring by magnetic resonance ⬇️

scientific article published on April 25, 2013

High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial.

scientific article

Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes

Impaired cardiovascular function in primary biliary cirrhosis

scientific article

Impaired cardiovascular response to standing in chronic fatigue syndrome

scientific article published on 23 May 2010

Impaired cerebral autoregulation in primary biliary cirrhosis: implications for the pathogenesis of cognitive decline.

scientific article

Improving the early management of blood glucose in emergency admissions with chest pain

In vitro study of human skeletal muscle strips: effect of nonesterified fatty acid supply on glucose storage

scientific article

Increased daily walking improves lipid oxidation without changes in mitochondrial function in type 2 diabetes.

scientific article published on 16 May 2008

Inducing remission of Type 2 diabetes in the Caribbean: findings from a mixed methods feasibility study of a low-calorie liquid diet-based intervention in Barbados

scientific article published on 31 July 2019

Ingestion of glucose or sucrose prevents liver but not muscle glycogen depletion during prolonged endurance-type exercise in trained cyclists

scientific article

Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates

scientific article

Insulin Resistance and Type 2 Diabetes ⬇️

scientific article published on April 1, 2012

Insulin resistance: circumventing nature's blocks

scientific article published on 01 October 1996

Insulin sensitivity and fertility.

scientific article

Insulin sensitivity in experimental cirrhosis

scientific article published on August 1989

Intrauterine growth rate in pregnancies complicated by type 1, type 2 and gestational diabetes.

scientific article published on March 2009

Levothyroxine improves abnormal cardiac bioenergetics in subclinical hypothyroidism: a cardiac magnetic resonance spectroscopic study

scientific article published on 26 December 2014

Liver triacylglycerol content and gestational diabetes: effects of moderate energy restriction

scientific article published on 5 November 2016

Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in primary biliary cirrhosis

scientific article published on 31 March 2010

Low-calorie diets for people with isolated impaired fasting glucose

Management of non-insulin-dependent diabetes

scientific article

Measuring the acute effect of insulin infusion on ATP turnover rate in human skeletal muscle using phosphorus-31 magnetic resonance saturation transfer spectroscopy.

scientific article

Mechanism of metabolic advantages after bariatric surgery: it's all gastrointestinal factors versus it's all food restriction.

scientific article published on August 2013

Medical Masterclass, Royal College of Physicians, Editor-inchief John D Firth. Blackwell Science 2001

Medical training in the UK: sleepwalking to disaster

scientific article

Modernising Medical Careers, Medical Training Application Service, and the Postgraduate Medical Education and Training Board: time for the emperors to don their clothes

scientific article published in The Lancet

Morphology of the pancreas in type 2 diabetes: effect of weight loss with or without normalisation of insulin secretory capacity

scientific article published on 14 May 2016

Movement as Medicine for Type 2 Diabetes: protocol for an open pilot study and external pilot clustered randomised controlled trial to assess acceptability, feasibility and fidelity of a multifaceted behavioural intervention targeting physical activ

scientific article

Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls

scientific article

Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker

scientific article

Normal weight individuals who develop type 2 diabetes: the personal fat threshold

scientific article published on April 2015

Pancreatic triacylglycerol distribution in type 2 diabetes

scientific article published on 2 August 2015

Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis

scientific article published on 8 August 2008

Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content

scientific article published on 5 June 2008

Population response to information on reversibility of Type 2 diabetes

scientific article published in April 2013

Post-prandial thermogenesis and insulin sensitivity in the polycystic ovary syndrome

scientific article

Postgraduate training and/or education?

Prevention and reversal of Type 2 diabetes: highlights from a symposium at the 2019 Diabetes UK Annual Professional Conference

scientific article published on 25 January 2019

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial.

scientific article published on 4 December 2017

Quantification of intrapancreatic fat in type 2 diabetes by MRI.

scientific article

Regulation of endogenous glucose production after a mixed meal in type 2 diabetes

scientific article

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery

scientific article published on 01 October 2018

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery

scientific article published on 02 August 2018

Remission of type 2 diabetes by weight loss in a non-white population

scientific article published on 01 June 2020

Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss ⬇️

scientific article published on June 27, 2011

Resistance to Injection: 1991 RD Lawrence Lecture ⬇️

scientific article published on March 1, 1992

Response to Comment on: Chen et al. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010;33:2552–2554

Response to Comment on: Chen et al. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010;33:2552–2554.

scientific article

Restoring normoglycaemia by use of a very low calorie diet in long- and short-duration Type 2 diabetes

scientific article published on 12 February 2015

Reversal of Type 2 diabetes after bariatric surgery is determined by the degree of achieved weight loss in both short- and long-duration diabetes

scientific article published on 12 September 2014

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.

scientific article

Screening for diabetic retinopathy

scientific article published in May 2003

Severe impairment of insulin action in adipocytes from amenorrheic subjects with polycystic ovary syndrome

scientific article published on 01 December 1994

Sucrose ingestion after exhaustive exercise accelerates liver, but not muscle glycogen repletion compared with glucose ingestion in trained athletes

scientific article published on 24 March 2016

Systematic development of a theory-informed multifaceted behavioural intervention to increase physical activity of adults with type 2 diabetes in routine primary care: Movement as Medicine for Type 2 Diabetes

scientific article

The DiRECT principles: giving Type 2 diabetes remission programmes the best chance of success

scientific article published on 11 October 2019

The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial

scientific article published on 16 February 2016

The degree of hepatic steatosis associates with impaired cardiac and autonomic function

scientific article published on 13 February 2019

The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT)

The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.

scientific article published on 16 October 2008

The second-meal phenomenon in type 2 diabetes

scientific article

The second-meal phenomenon is associated with enhanced muscle glycogen storage in humans

scientific article published on 2 July 2009

Time Course of Normalization of Functional β-Cell Capacity in the Diabetes Remission Clinical Trial After Weight Loss in Type 2 Diabetes

scientific article published on 14 February 2020

Tissue insulin sensitivity and body weight in polycystic ovary syndrome

scientific article

Translating aetiological insight into sustainable management of type 2 diabetes.

scientific article published on 15 November 2017

Treating gestational diabetes reduces perinatal morbidity

scientific article published on 14 April 2014

Treatment of periodontitis reduces systemic inflammation in type 2 diabetes

scientific article published on 27 February 2020

Type 1 diabetes and pregnancy

scientific article published on April 2007

Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology

scientific article published on 02 December 2020

Type 2 Diabetes: The Pathologic Basis of Reversible β-Cell Dysfunction

scientific article published on November 2016

Type 2 diabetes remission: 2 year within-trial and lifetime-horizon cost-effectiveness of the Diabetes Remission Clinical Trial (DiRECT)/Counterweight-Plus weight management programme

scientific article published on 10 August 2020

Type 2 diabetes, bariatric surgery and the risk of subsequent gestational diabetes

scientific article published on 15 September 2011

Understanding the mechanisms of reversal of type 2 diabetes

scientific article published on 13 May 2019

Use of adipose tissue for metabolic studies

scientific article

Using trials of caloric restriction and bariatric surgery to explore the effects of body mass index on the circulating proteome

Utilizing the second-meal effect in type 2 diabetes: practical use of a soya-yogurt snack ⬇️

scientific article

VLCD for weight loss and remission of type 2 diabetes? - Authors' reply

scientific article published in The Lancet

Very Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiological Changes in Responders and Nonresponders.

scientific article published on 21 March 2016

Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes

scientific article published in December 2015

Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial

scientific article published on 02 December 2020

When is HbA1c useful and what do the numbers mean – do they help or hinder?

Within-trial cost and 1-year cost-effectiveness of the DiRECT/Counterweight-Plus weight-management programme to achieve remission of type 2 diabetes

scientific article published on 20 December 2018

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