List of works - Stefan Hofbauer

A stable bacterial peroxidase with novel halogenating activity and an autocatalytically linked heme prosthetic group

scientific article

Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation

scientific article published on 09 April 2020

Agaricus meleagris pyranose dehydrogenase: influence of covalent FAD linkage on catalysis and stability.

scientific article published on 17 July 2014

Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis

scientific article published on 15 February 2021

Biochemical characterization of the major N-acetylmuramidase from Lactobacillus buchneri

scientific article published on 24 May 2014

Chemistry and Molecular Dynamics Simulations of Heme b-HemQ and Coproheme-HemQ.

scientific article

Chlorite dismutases - a heme enzyme family for use in bioremediation and generation of molecular oxygen.

scientific article published on 12 February 2014

Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.

scientific article

Coproheme decarboxylases - Phylogenetic prediction versus biochemical experiments

scientific article published on 10 January 2018

Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase

scientific article published on 03 December 2019

Dimeric chlorite dismutase from the nitrogen-fixing cyanobacterium Cyanothece sp. PCC7425

scientific article

Eukaryotic Catalase-Peroxidase: The Role of the Trp-Tyr-Met Adduct in Protein Stability, Substrate Accessibility, and Catalysis of Hydrogen Peroxide Dismutation

scientific article

From chlorite dismutase towards HemQ - the role of the proximal H-bonding network in haeme binding

scientific article published on 8 February 2016

Hydrogen peroxide-mediated conversion of coproheme to heme b by HemQ-lessons from the first crystal structure and kinetic studies.

scientific article

Impact of subunit and oligomeric structure on the thermal and conformational stability of chlorite dismutases

scientific article published on 6 June 2012

Inactivation of human myeloperoxidase by hydrogen peroxide

scientific article

Independent evolution of four heme peroxidase superfamilies

scientific article

Initial Steps to Engineer Coproheme Decarboxylase to Obtain Stereospecific Monovinyl, Monopropionyl Deuterohemes

scientific article published on 01 January 2021

Insights into the Active Site of Coproheme Decarboxylase from Listeria monocytogenes.

scientific article

Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM

scientific article published on 5 March 2015

Investigation of ion binding in chlorite dismutases by means of molecular dynamics simulations

scientific article published on 14 July 2014

Manipulating Conserved Heme Cavity Residues of Chlorite Dismutase: Effect on Structure, Redox Chemistry, and Reactivity

scientific article

Mechanism of chlorite degradation to chloride and dioxygen by the enzyme chlorite dismutase.

scientific article

Mechanism of reaction of chlorite with mammalian heme peroxidases

scientific article published on 28 February 2014

Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies.

scientific article published on 13 October 2017

Monomeric and homotrimeric solution structures of truncated human peroxidasin 1 variants

scientific article published on 08 July 2019

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions

scientific article published on 27 March 2019

Posttranslational Modification of Heme b in a Bacterial Peroxidase: The Role of Heme to Protein Ester Bonds in Ligand Binding and Catalysis.

scientific article

Posttranslational modification of heme in peroxidases - Impact on structure and catalysis.

scientific article published on 17 February 2018

Pre-steady-state Kinetics Reveal the Substrate Specificity and Mechanism of Halide Oxidation of Truncated Human Peroxidasin 1

scientific article

Reaction of human peroxidasin 1 compound I and compound II with one-electron donors

scientific article published on 15 January 2020

Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme b

scientific article published on 18 June 2019

Redox thermodynamics of B-class dye-decolorizing peroxidases

scientific article published on 11 July 2019

Redox thermodynamics of high-spin and low-spin forms of chlorite dismutases with diverse subunit and oligomeric structures

scientific article

Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage

scientific article published in Journal of Biological Chemistry

Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking

scientific article published on 23 September 2015

Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes

scientific article published on 17 January 2015

Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation

scientific article

The hydrogen bonding network of coproheme in coproheme decarboxylase from Listeria monocytogenes: Effect on structure and catalysis

scientific article published on 21 March 2019

The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

scientific article published on 30 May 2020

Transiently produced hypochlorite is responsible for the irreversible inhibition of chlorite dismutase

scientific article

Understanding molecular enzymology of porphyrin-binding α + β barrel proteins - One fold, multiple functions

scientific article published on 03 September 2020

X-ray induced photoreduction of heme metal centers rapidly induces active site perturbations in a protein-independent manner

scientific article published on 28 July 2020

List of works by Stefan Hofbauer

A stable bacterial peroxidase with novel halogenating activity and an autocatalytically linked heme prosthetic group

Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation

Agaricus meleagris pyranose dehydrogenase: influence of covalent FAD linkage on catalysis and stability.

Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis

Biochemical characterization of the major N-acetylmuramidase from Lactobacillus buchneri

Chemistry and Molecular Dynamics Simulations of Heme b-HemQ and Coproheme-HemQ.

Chlorite dismutases - a heme enzyme family for use in bioremediation and generation of molecular oxygen.

Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.

Coproheme decarboxylases - Phylogenetic prediction versus biochemical experiments

Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase

Dimeric chlorite dismutase from the nitrogen-fixing cyanobacterium Cyanothece sp. PCC7425

Eukaryotic Catalase-Peroxidase: The Role of the Trp-Tyr-Met Adduct in Protein Stability, Substrate Accessibility, and Catalysis of Hydrogen Peroxide Dismutation

From chlorite dismutase towards HemQ - the role of the proximal H-bonding network in haeme binding

Hydrogen peroxide-mediated conversion of coproheme to heme b by HemQ-lessons from the first crystal structure and kinetic studies.

Impact of subunit and oligomeric structure on the thermal and conformational stability of chlorite dismutases

Inactivation of human myeloperoxidase by hydrogen peroxide

Independent evolution of four heme peroxidase superfamilies

Initial Steps to Engineer Coproheme Decarboxylase to Obtain Stereospecific Monovinyl, Monopropionyl Deuterohemes

Insights into the Active Site of Coproheme Decarboxylase from Listeria monocytogenes.

Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM

Investigation of ion binding in chlorite dismutases by means of molecular dynamics simulations

Manipulating Conserved Heme Cavity Residues of Chlorite Dismutase: Effect on Structure, Redox Chemistry, and Reactivity

Mechanism of chlorite degradation to chloride and dioxygen by the enzyme chlorite dismutase.

Mechanism of reaction of chlorite with mammalian heme peroxidases

Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies.

Monomeric and homotrimeric solution structures of truncated human peroxidasin 1 variants

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions

Posttranslational Modification of Heme b in a Bacterial Peroxidase: The Role of Heme to Protein Ester Bonds in Ligand Binding and Catalysis.

Posttranslational modification of heme in peroxidases - Impact on structure and catalysis.

Pre-steady-state Kinetics Reveal the Substrate Specificity and Mechanism of Halide Oxidation of Truncated Human Peroxidasin 1

Reaction of human peroxidasin 1 compound I and compound II with one-electron donors

Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme b

Redox thermodynamics of B-class dye-decolorizing peroxidases

Redox thermodynamics of high-spin and low-spin forms of chlorite dismutases with diverse subunit and oligomeric structures

Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage

Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking

Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes

Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation

The hydrogen bonding network of coproheme in coproheme decarboxylase from Listeria monocytogenes: Effect on structure and catalysis

The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

Transiently produced hypochlorite is responsible for the irreversible inhibition of chlorite dismutase

Understanding molecular enzymology of porphyrin-binding α + β barrel proteins - One fold, multiple functions

X-ray induced photoreduction of heme metal centers rapidly induces active site perturbations in a protein-independent manner

Understanding molecular enzymology of porphyrin-binding α + β barrel proteins - One fold, multiple functions