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List of works by Balázs Hegedűs

A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes

scientific article

A comparison of sample preparation strategies for biological tissues and subsequent trace element analysis using LA-ICP-MS.

scientific article

Angiogenesis and angiogenic tyrosine kinase receptor expression in pediatric brain tumors

scientific article published on 5 November 2013

Antimicrobial peptides are highly abundant and active in postoperative pleural drainage fluids

scientific article published on 16 July 2014

Apelin expression in human non-small cell lung cancer: role in angiogenesis and prognosis

scientific article published on 01 August 2010

Application of dried-droplets deposited on pre-cut filter paper disks for quantitative LA-ICP-MS imaging of biologically relevant minor and trace elements in tissue samples

scientific article published on 11 January 2016

BARD1 serum autoantibodies for the detection of lung cancer.

scientific article

Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis

scientific article

Cell migration or cytokinesis and proliferation?--revisiting the "go or grow" hypothesis in cancer cells in vitro.

scientific article

Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma

scientific article published in November 2005

Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study.

scientific article published on 8 June 2016

Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma.

scientific article published on 28 November 2017

Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma

scientific article published on 16 January 2014

Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features

scientific article published on 07 January 2020

Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma

scientific article published on 14 March 2020

DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells.

scientific article published on 10 May 2018

Detection and measurement of neurofibromatosis-1 mouse optic glioma in vivo

scientific article published on 23 February 2007

Detection of TGF-β in pleural effusions for diagnosis and prognostic stratification of malignant pleural mesothelioma

scientific article published on 18 November 2019

Differences in the Epidemiology of Rare EGFR Mutations in Different Populations

scientific article published in January 2016

Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis

scientific article

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

scientific article published on May 2015

Dystroglycan is involved in laminin-1-stimulated motility of Müller glial cells: combined velocity and directionality analysis

scientific article published on 01 March 2005

Effectiveness of erlotinib treatment in advanced KRAS mutation-negative lung adenocarcinoma patients: Results of a multicenter observational cohort study (MOTIVATE).

scientific article published on 27 July 2014

Encephalitis and GABAB receptor antibodies: novel findings in a new case series of 20 patients

scientific article

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.

scientific article published on 26 May 2015

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma

scientific article

Expression of FGFR1-4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity

scientific article published on 16 September 2019

Expression of microRNA-21 in non-small cell lung cancer tissue increases with disease progression and is likely caused by growth conditional changes during malignant transformation

scientific article published on 22 January 2014

FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.

scientific article published in April 2018

FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo.

scientific article published on 23 September 2017

Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.

scientific article published on October 2014

Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis

scientific article

From Bench to Bedside: Attempt to Evaluate Repositioning of Drugs in the Treatment of Metastatic Small Cell Lung Cancer (SCLC)

scientific article

HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line

scientific article published on 26 June 2020

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

scientific article

Horizontal Combination of MEK and PI3K/mTOR Inhibition in BRAF Mutant Tumor Cells with or without Concomitant PI3K Pathway Mutations

scientific article published on 16 October 2020

IL-24 sensitizes tumor cells to TLR3-mediated apoptosis

scientific article published on March 2013

Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes

scientific article published on 17 January 2011

Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma

scientific article published on 29 October 2020

Implementation of an experimental isolated lung perfusion model on surgically resected human lobes

scientific article published on 21 August 2019

Inhibition of epidermal growth factor receptor improves antitumor efficacy of vemurafenib in BRAF-mutant human melanoma in preclinical model

scientific article published on 01 December 2018

Intrathoracic solitary fibrous tumor - an international multicenter study on clinical outcome and novel circulating biomarkers

scientific article published on 2 October 2017

Invasion from a cell aggregate--the roles of active cell motion and mechanical equilibrium.

scientific article

Irradiation and Taxol treatment result in non-monotonous, dose-dependent changes in the motility of glioblastoma cells

scientific article published on March 2004

KRAS Mutations Predict Response and Outcome in Advanced Lung Adenocarcinoma Patients Receiving First-Line Bevacizumab and Platinum-Based Chemotherapy

scientific article published on 09 October 2019

KRAS mutation testing of colorectal cancer for anti-EGFR therapy: dogmas versus evidence.

scientific article published on December 2010

KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS mutation and bone metastasis.

scientific article published on 04 January 2017

KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models

scientific article published on 21 October 2016

Ki67 index is an independent prognostic factor in epithelioid but not in non-epithelioid malignant pleural mesothelioma: a multicenter study

scientific article published on 29 January 2015

Laminin-1 increases motility, path-searching, and process dynamism of rat and mouse Muller glial cells in vitro: implication of relationship between cell behavior and formation of retinal morphology

scientific article

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors

scientific article

Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study

scientific article

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression

scientific article published on 11 September 2019

Lung cancer in never smokers.

scientific article published on October 2011

Lymph Node Involvement and the Surgical Treatment of Thymic Epithelial and Neuroendocrine Carcinoma

scientific article published on 02 February 2019

Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer

scientific article published on 17 January 2022

Mononuclear cell secretome protects from experimental autoimmune myocarditis

scientific article

Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms

scientific article published on 01 October 2007

Neutrophil-lymphocyte ratio is prognostic in early stage resected small-cell lung cancer

scientific article published on 29 July 2019

New insights into the impact of primary lung adenocarcinoma location on metastatic sites and sequence: A multicenter cohort study

scientific article published on 05 November 2018

Next Generation Lipophilic Bisphosphonate Shows Antitumor Effect in Colorectal Cancer In Vitro and In Vivo

scientific article published on 04 January 2020

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo

scientific article published on 03 May 2018

Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes

scientific article

Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo

scientific article

Optic nerve dysfunction in a mouse model of neurofibromatosis-1 optic glioma.

scientific article published on May 2009

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells.

scientific article published on 8 May 2018

Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer

scientific article published on 04 February 2020

Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.

scientific article published in March 2008

Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells

scientific article

Pretreatment serum C-reactive protein levels predict benefit from multimodality treatment including radical surgery in malignant pleural mesothelioma: a retrospective multicenter analysis

scientific article published in August 2012

Primary Human Fibroblasts in Culture Switch to a Myofibroblast-Like Phenotype Independently of TGF Beta

scientific article published on 13 July 2019

Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters

scientific article published on 01 December 2019

RIG-I inhibits the MAPK-dependent proliferation of BRAF mutant melanoma cells via MKP-1.

scientific article published on 29 January 2016

Reply to Rare Versus Artifactual EGFR Mutations

scientific article published on 01 August 2015

Reshaping a multimode laser beam into a constructed Gaussian beam for generating a thin light sheet

scientific article published on 19 February 2018

Same-day Routine Chest-X Ray After Thoracic Surgery is Not Necessary!

scientific article published on 13 September 2017

Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations

scientific article published on 9 March 2015

Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases

scientific article

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy

scientific article

Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells ⬇️

scientific article published on November 20, 2012

Targeting an Oncolytic Influenza A Virus to Tumor Tissue by Elastase.

scientific article published on 8 September 2017

Telomerase reverse transcriptase promoter mutations identify a genomically defined and highly aggressive human pleural mesothelioma subgroup

scientific article published on 21 April 2020

Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy

scientific article

The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb

scientific article published on 03 October 2019

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma

scientific article published on 11 December 2018

The neurobiology of neurooncology.

scientific article published on July 2006

The role of Allee effect in modelling post resection recurrence of glioblastoma.

scientific article published on 17 November 2017

The role of lipid signaling in the progression of malignant melanoma

scientific article published on 01 September 2018

The role of microRNAs in the diagnosis and treatment of malignant pleural mesothelioma--a short review.

scientific article

Trabectedin Is Active against Malignant Pleural Mesothelioma Cell and Xenograft Models and Synergizes with Chemotherapy and Bcl-2 Inhibition In Vitro

scientific article published on 10 August 2016

Tumor type-specific and skin region-selective metastasis of human cancers: another example of the “seed and soil” hypothesis ⬇️

scientific article published on December 1, 2013

Ultrastructural characterization of the optic pathway in a mouse model of neurofibromatosis-1 optic glioma

scientific article

Vessel co-option is common in human lung metastases and mediates resistance to anti-angiogenic therapy in preclinical lung metastasis models ⬇️

scientific article

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