List of works - Valentina Vaira

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression

scientific article published on 25 August 2021

A neuronal network of mitochondrial dynamics regulates metastasis

scientific article

A new mouse avatar model of non-small cell lung cancer.

scientific article

Aberrant overexpression of the cell polarity module scribble in human cancer

scientific article (publication date: June 2011)

Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

scientific article

Analysis of NSCLC tumour heterogeneity, proliferative and 18F-FDG PET indices reveals Ki67 prognostic role in adenocarcinomas

scientific article published on 14 August 2015

Carcinosarcoma of the colon: report of a case with morphological, ultrastructural and molecular analysis

scientific article published on 12 July 2006

Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.

scientific article published on 14 May 2012

Comprehensive Genomic Analysis Reveals the Prognostic Role of LRRK2 Copy-Number Variations in Human Malignancies

scientific article published on 24 July 2020

Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s ⬇️

scientific article published on September 11, 2012

Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression

scientific article published on 24 June 2015

Deregulation of miRNAs-cMYC circuits is a key event in refractory celiac disease type-2 lymphomagenesis

scientific article published on 18 May 2020

Different expression of protein kinase A (PKA) regulatory subunits in normal and neoplastic thyroid tissues

scientific article

Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue

scientific article

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

scientific article

EGFR overexpression in malignant pleural mesothelioma

scientific article published on 27 December 2005

Epigenetic alterations in cancer and personalized cancer treatment

scientific article

Epigenetic alterations in human parathyroid tumors

scientific article published on 27 February 2015

Expression of C19MC miRNAs in HCC associates with stem-cell features and the cancer-testis genes signature.

scientific article published on 30 March 2018

Expression, function, and regulation of the embryonic transcription factor TBX1 in parathyroid tumors.

scientific article published on 18 September 2017

Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors.

scientific article published on 21 November 2016

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability

scientific article published on 01 February 2022

IMP3 expression in NSCLC brain metastases demonstrates its role as a prognostic factor in non-neuroendocrine phenotypes.

scientific article published in December 2017

Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model

scientific article

Immunological effects of transglutaminase-treated gluten in coeliac disease

scientific article published on 23 July 2012

Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.

scientific article

Interferon lambda-3 is not associated with clinical outcome in patients with HCV-induced compensated cirrhosis: a long-term cohort study

scientific article published on 11 November 2014

Interplay between V-ATPase G1 and small EV-miRNAs modulates ERK1/2 activation in GBM stem cells and non-neoplastic milieu

scientific article published on 04 August 2020

MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

scientific article published on 03 October 2019

MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state

scientific article published on 9 March 2018

Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models

scientific article published on 6 December 2017

MicroRNA as potential biomarker in HCV-associated diffuse large B-cell lymphoma

scientific article published on 9 June 2014

MicroRNA deregulation in parathyroid tumours suggests an embryonic signature.

scientific article published on 11 January 2015

MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma

scientific article published on 19 March 2012

MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma

scientific article published on 21 July 2014

MicroRNAs in parathyroid physiopathology

scientific article published on 2 November 2016

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

scientific journal article

Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer

scientific article published on 18 September 2019

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors

scientific article published on 26 December 2016

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

scientific article

Pseudohypoparathyroidism andGNASEpigenetic Defects: Clinical Evaluation of Albright Hereditary Osteodystrophy and Molecular Analysis in 40 Patients

article

Quantitative Multivolume Proton-Magnetic Resonance Imaging in Lung Transplant Recipients: Comparison With Computed Tomography and Spirometry

scientific article published on 08 July 2020

Regulation of lung cancer metastasis by Klf4-Numb-like signaling

scientific article published on 25 February 2013

Regulation of survivin expression by IGF-1/mTOR signaling

scientific article published on 30 October 2006

Role of Strain Rate in the Pathogenesis of Ventilator-Induced Lung Edema.

scientific article

Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.

scientific article

The Contrasting Role of p16Ink4A Patterns of Expression in Neuroendocrine and Non-Neuroendocrine Lung Tumors: A Comprehensive Analysis with Clinicopathologic and Molecular Correlations

scientific article published on 16 December 2015

The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.

scientific article

The Oncofetal Protein IMP3: A Useful Marker to Predict Poor Clinical Outcome in Neuroendocrine Tumors of the Lung

scientific article published on 01 November 2014

The aberrantly expressed miR-372 partly impairs sensitivity to apoptosis in parathyroid tumor cells

scientific article published on 03 May 2018

The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma ⬇️

scientific article published on January 29, 2013

The microRNA cluster C19MC is deregulated in parathyroid tumours.

scientific article published on 26 July 2012

The oncofetal protein IMP3: a novel grading tool and predictor of poor clinical outcome in human gliomas.

scientific article published on 28 January 2015

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.

scientific article

Transglutaminase 2 Mediates the Cytotoxicity of Resveratrol in a Human Cholangiocarcinoma and Gallbladder Cancer Cell Lines

scientific article published on 14 May 2018

Up-regulation of focal adhesion kinase in non-small cell lung cancer

scientific article published on 13 July 2006

miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression.

scientific article published on 6 June 2011

miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo

scientific article published on August 2014

miR-494-3p is a novel tumor driver of lung carcinogenesis

scientific article published on 14 December 2016

microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts.

scientific article published in March 2014

List of works by Valentina Vaira

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression

A neuronal network of mitochondrial dynamics regulates metastasis

A new mouse avatar model of non-small cell lung cancer.

Aberrant overexpression of the cell polarity module scribble in human cancer

Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

Analysis of NSCLC tumour heterogeneity, proliferative and 18F-FDG PET indices reveals Ki67 prognostic role in adenocarcinomas

Carcinosarcoma of the colon: report of a case with morphological, ultrastructural and molecular analysis

Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.

Comprehensive Genomic Analysis Reveals the Prognostic Role of LRRK2 Copy-Number Variations in Human Malignancies

Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s ⬇️

Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression

Deregulation of miRNAs-cMYC circuits is a key event in refractory celiac disease type-2 lymphomagenesis

Different expression of protein kinase A (PKA) regulatory subunits in normal and neoplastic thyroid tissues

Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

EGFR overexpression in malignant pleural mesothelioma

Epigenetic alterations in cancer and personalized cancer treatment

Epigenetic alterations in human parathyroid tumors

Expression of C19MC miRNAs in HCC associates with stem-cell features and the cancer-testis genes signature.

Expression, function, and regulation of the embryonic transcription factor TBX1 in parathyroid tumors.

Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors.

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability

IMP3 expression in NSCLC brain metastases demonstrates its role as a prognostic factor in non-neuroendocrine phenotypes.

Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model

Immunological effects of transglutaminase-treated gluten in coeliac disease

Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.

Interferon lambda-3 is not associated with clinical outcome in patients with HCV-induced compensated cirrhosis: a long-term cohort study

Interplay between V-ATPase G1 and small EV-miRNAs modulates ERK1/2 activation in GBM stem cells and non-neoplastic milieu

MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state

Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models

MicroRNA as potential biomarker in HCV-associated diffuse large B-cell lymphoma

MicroRNA deregulation in parathyroid tumours suggests an embryonic signature.

MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma

MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma

MicroRNAs in parathyroid physiopathology

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

Pseudohypoparathyroidism andGNASEpigenetic Defects: Clinical Evaluation of Albright Hereditary Osteodystrophy and Molecular Analysis in 40 Patients

Quantitative Multivolume Proton-Magnetic Resonance Imaging in Lung Transplant Recipients: Comparison With Computed Tomography and Spirometry

Regulation of lung cancer metastasis by Klf4-Numb-like signaling

Regulation of survivin expression by IGF-1/mTOR signaling

Role of Strain Rate in the Pathogenesis of Ventilator-Induced Lung Edema.

Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.

The Contrasting Role of p16Ink4A Patterns of Expression in Neuroendocrine and Non-Neuroendocrine Lung Tumors: A Comprehensive Analysis with Clinicopathologic and Molecular Correlations

The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.

The Oncofetal Protein IMP3: A Useful Marker to Predict Poor Clinical Outcome in Neuroendocrine Tumors of the Lung

The aberrantly expressed miR-372 partly impairs sensitivity to apoptosis in parathyroid tumor cells

The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma ⬇️

The microRNA cluster C19MC is deregulated in parathyroid tumours.

The oncofetal protein IMP3: a novel grading tool and predictor of poor clinical outcome in human gliomas.

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.

Transglutaminase 2 Mediates the Cytotoxicity of Resveratrol in a Human Cholangiocarcinoma and Gallbladder Cancer Cell Lines

Up-regulation of focal adhesion kinase in non-small cell lung cancer

miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression.

miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo

miR-494-3p is a novel tumor driver of lung carcinogenesis

microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts.