Search filters

List of works by Matthias Hamburger

(+)-N-Deoxymilitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus

scientific article published on March 2006

(E,Z)-3-(3',5'-Dimethoxy-4'-hydroxy-benzylidene)-2-indolinone blocks mast cell degranulation

scientific article published on 27 March 2010

4-(Difluoromethyl)-5-(4-((3R,5S)-3,5-dimethylmorpholino)-6-((R)-3-methylmorpholino)-1,3,5-triazin-2-yl)pyridin-2-amine (PQR626), a Potent, Orally Available, and Brain-Penetrant mTOR Inhibitor for the Treatment of Neurological Disorders

scientific article published on 09 November 2020

4th Pediatric Allergy and Asthma Meeting (PAAM)

scientific article (publication date: November 2016)

7. Bioactivity in plants: the link between phytochemistry and medicine

scientific article published in 1991

70th Birthday of Prof. Dr. rer. nat. Dr. h. c. Adolf Nahrstedt

scientific article published on September 10, 2010

75th Birthday of Prof. Dr. rer. nat. Dres. h. c. Adolf Nahrstedt

scientific article published on 28 July 2015

A Bufadienolide-Enriched Fraction of Bryophyllum pinnatum Inhibits Human Myometrial Contractility In Vitro

scientific article published on 18 December 2018

A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells

scientific article published on 9 November 2022

A FLIPR Assay for Discovery of GABAA Receptor Modulators of Natural Origin

scientific article published on 24 May 2019

A New Pyranocoumarin Diester fromPolygala paniculata L

scientific article published on 28 December 2004

A Novel Type of Dimeric Secoiridoid Glycoside fromLisianthius jefensis ROBYNSet ELIAS

A comparative study on the skin penetration of pure tryptanthrin and tryptanthrin in Isatis tinctoria extract by dermal microdialysis coupled with isotope dilution ESI-LC-MS.

scientific article

A comprehensive metabolite profiling of Isatis tinctoria leaf extracts

scientific article

A multicomponent herbal feed additive improves somatic cell counts in dairy cows - a two stage, multicentre, placebo-controlled long-term on-farm trial

scientific article published on 05 February 2020

A nor-diterpene from Salvia sahendica leaves

scientific article published on 16 February 2017

A protocol for HPLC-based activity profiling for natural products with activities against tropical parasites

scientific article

A simple isolation method for the major catechins in green tea using high-speed countercurrent chromatography

scientific article

A simple method for preparation of D-rhamnose

scientific article

Abietane Diterpenoids from Salvia sahendica – Antiprotozoal Activity and Determination of Their Absolute Configurations

scientific article published on January 8, 2013

Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

scientific article published on 18 January 2019

Acetylated saponins with molluscicidal activity fromSapindus rarak: Unambiguous structure determination by proton nuclear magnetic resonance and quantitative analysis

scientific article published on 7 March 2007

Acid-Induced Rearrangement of Epoxygermacranolides: Synthesis of Furanoheliangolides and Cadinanes from Nobilin.

scientific article published on 18 December 2017

Activities of Psilostachyin A and Cynaropicrin against Trypanosoma cruzi In Vitro and In Vivo

scientific article published on August 12, 2013

Albert Hofmann (1906 - 2008) - an obituary

scientific article published in June 2008

An Antifungal Isoflavanone and a Structure Revision of a Flavanone from Erythrina berteroana

scientific article published on 01 June 1989

An antifungal triterpenoid from mollugo pentaphylla

scientific article published on 25 July 2002

Analysis of aspartyl peptide degradation products by high-performance liquid chromatography and high-performance liquid chromatography-mass spectrometry

scientific article published in January 2004

Analytical aspects of drugs of natural origin

scientific article

Andrographolide-loaded nanoparticles for brain delivery: Formulation, characterisation and in vitro permeability using hCMEC/D3 cell line

scientific article

Anti-Candida Cassane-Type Diterpenoids from the Root Bark of Swartzia simplex.

scientific article published on 11 December 2015

Anti-arthritic activity of a lipophilic woad (Isatis tinctoria) extract

scientific article published on 31 May 2006

Anti-inflammatory and antiallergic activity in vivo of lipophilic Isatis tinctoria extracts and tryptanthrin

scientific article

Anti-proliferative activity-guided isolation of clerodermic acid from Salvia nemorosa L.: Geno/cytotoxicity and hypoxia-mediated mechanism of action

scientific article published on 28 June 2018

Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae)

scientific article published on 27 February 2013

Anti-trypanosomal cadinanes synthesized by transannular cyclization of the natural sesquiterpene lactone nobilin

scientific article published on 13 February 2015

Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana

scientific article published on 17 March 2020

Antibacterial and Hypoglycemic Diterpenoids from Salvia chamaedryoides

scientific article

Antibacterial compounds from Salvia adenophora Fernald (Lamiaceae)

scientific article published on 27 November 2014

Antifungal biphenyls from Monnina sylvatica

scientific article published on 01 April 1991

Antifungal tests in phytochemical investigations: comparison of bioautographic methods using phytopathogenic and human pathogenic fungi

scientific article published on 01 February 1994

Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)

scientific article published in 2014

Antimicrobial flavonoids from Psiadia trinervia and their methylated and acetylated derivatives

scientific article published on 25 July 2002

Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids

scientific article

Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.

scientific article published on 16 March 2011

Antiplasmodial lanostanes from the Ganoderma lucidum mushroom

scientific article published in May 2010

Antiplasmodial, anti-trypanosomal, anti-leishmanial and cytotoxicity activity of selected Tanzanian medicinal plants

scientific article

Antiplasmodial, anti-trypanosomal, anti-leishmanial and cytotoxicity activity of selected Tanzanian medicinal plants

article

Antiprotozoal Activity-Based Profiling of a Dichloromethane Extract from Anthemis nobilis Flowers.

scientific article published on 24 January 2017

Antiprotozoal Diterpenes from Perovskia abrotanoides.

scientific article published on 26 April 2018

Antiprotozoal Germacranolide Sesquiterpene Lactones from Tanacetum sonbolii

scientific article published on 08 January 2019

Antiprotozoal Isoprenoids from Salvia hydrangea

scientific article published on 19 December 2018

Antiprotozoal activity of diterpenoids isolated from Zhumeria majdae- absolute configuration by circular dichroism

scientific article published on 11 May 2020

Antiprotozoal isoflavan quinones from Abrus precatorius ssp. africanus

scientific article

Antiprotozoal screening of 60 South African plants, and the identification of the antitrypanosomal germacranolides schkuhrin I and II.

scientific article

Antistaphylococcal Prenylated Acylphoroglucinol and Xanthones from Kielmeyera variabilis

scientific article published on 22 February 2016

Antitrypanosomal isoflavan quinones from Abrus precatorius

scientific article published on 29 December 2013

Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina

scientific article

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

scientific article published on 14 October 2014

Antitrypanosomal sesquiterpene lactones from Saussurea costus

scientific article published on 23 May 2011

Antitrypanosomal structure-activity-relationship study of synthetic cynaropicrin derivatives

scientific article published on 2 January 2014

Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis

scientific article published on 5 September 2013

Are extraction methods in quantitative assays of pharmacopoeia monographs exhaustive? A comparison with pressurized liquid extraction

scientific article published on 21 August 2006

Aryltetralin lignans from Hyptis brachiata inhibiting T lymphocyte proliferation

scientific article published in 2023

Automated Comparative Metabolite Profiling of Large LC-ESIMS Data Sets in an ACD/MS Workbook Suite Add-in, and Data Clustering on a New Open-Source Web Platform FreeClust

scientific article

Bicyclononane aldehydes and antiproliferative constituents from Amomum tsao-ko

scientific article

Bioactive sesquiterpene coumarins from Ferula pseudalliacea

scientific article published on 19 August 2014

Biphenyls and a xanthone from monnina sylvatica

scientific article published on 25 July 2002

Bisabololoxide derivatives from Artemisia persica, and determination of their absolute configurations by ECD

scientific article published on 23 September 2012

Bitter Taste Impact and Thermal Conversion of a Naringenin Glycoside from Cyclopia genistoides

scientific article published on 04 December 2018

Boswellia carteri extract and 3-O-acetyl-alpha-boswellic acid suppress T cell function

scientific article published on 23 July 2020

Bryophyllum pinnatum and Related Species Used in Anthroposophic Medicine: Constituents, Pharmacological Activities, and Clinical Efficacy.

scientific article published on 24 May 2016

Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study

scientific article published on 04 November 2019

Bryophyllum pinnatum inhibits detrusor contractility in porcine bladder strips—A pharmacological study towards a new treatment option of overactive bladder

scientific article published on 21 July 2012

Caco-2 Permeability Studies and In Vitro hERG Liability Assessment of Tryptanthrin and Indolinone

scientific article published on 15 July 2016

Case Study of the Swiss Flora for Prior Phytochemical and Biological Investigations

scientific article published on January 29, 2013

Characterization of the pungent principles and the essential oil of Zanthoxylum schinifolium pericarp

scientific article published on 01 May 2007

Chemical composition of the bark of Tetrapterys mucronata and identification of acetylcholinesterase inhibitory constituents

scientific article published on 12 February 2014

Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity

scientific article published on 01 June 2012

Clerodane Diterpenes from Casearia corymbosa as Allosteric GABAₐ Receptor Modulators

scientific article published on 27 April 2022

Combined use of extract libraries and HPLC-based activity profiling for lead discovery: potential, challenges, and practical considerations

scientific article

Combining Activity Profiling with Advanced Annotation to Accelerate the Discovery of Natural Products Targeting Oncogenic Signaling in Melanoma

scientific article published on 31 May 2022

Comment on Comparison of protective effects between cultured Cordyceps militaris and natural Cordyceps sinensis against oxidative damage

scientific article published on 28 July 2007

Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies

scientific article

Composition of Indigo naturalis

scientific article

Compounds from Toddalia asiatica: Immunosuppressant Activity and Absolute Configurations

scientific article published on 01 October 2020

Comprehensive analysis of Cirsium spinosissimum Scop., a wild alpine food plant

scientific article

Comprehensive analysis of Phyteuma orbiculare L., a wild Alpine food plant

scientific article published on August 21, 2012

Comprehensive off-line CCC × LC-DAD-MS separation of Cyclopia pubescens Eckl. & Zeyh. phenolic compounds and structural elucidation of isolated compounds

scientific article published on 17 August 2020

Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays

scientific article published on April 1, 2013

Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities

scientific article published in September 2002

Correction to Eudesmane Sesquiterpenes from Verbesina lanata with Inhibitory Activity against Grapevine Downy Mildew

scientific article published on 16 February 2018

Corrigendum to "Andrographolide-loaded nanoparticles for brain delivery: Formulation, characterisation and in vitro permeability using hCMEC/D3 cell line" [Eur. J. Pharm. Biopharm. 119 (2017) 253-263].

scientific article

Coumarins from Polygala paniculata

Cyclohexanecarboxylic-Acid Derivatives fromPsiadia trinervia

scientific article published on 28 December 2004

Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei

scientific article published on 5 September 2013

Cynaropicrin: the first plant natural product with in vivo activity against Trypanosoma brucei

scientific article

Dammarane-type saponins from leaves of Ziziphus spina-christi

scientific article published on 06 March 2017

Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo

scientific article published on 22 February 2018

Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9

scientific article published on 10 January 2020

Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts.

scientific article published on 23 September 2009

Development and full validation of an UPLC-MS/MS method for the determination of an anti-allergic indolinone derivative in rat plasma, and application to a preliminary pharmacokinetic study

scientific article published on 21 June 2012

Development and full validation of an UPLC-MS/MS method for the quantification of the plant-derived alkaloid indirubin in rat plasma

scientific article

Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models

scientific article published on 27 May 2014

Dimeric xanthones from Garcinia livingstonei

scientific article published on 25 July 2002

Discovery of GABA(A) receptor modulator aristolactone in a commercial sample of the Chinese herbal drug "Chaihu" (Bupleurum chinense roots) unravels adulteration by nephrotoxic Aristolochia manshuriensis roots

scientific article published on 23 January 2012

Disesquiterpene and sesquiterpene coumarins from Ferula pseudalliacea, and determination of their absolute configurations

scientific article published on 20 March 2012

Drug Affinity Responsive Target Stability (DARTS) Identifies Laurifolioside as a New Clathrin Heavy Chain Modulator

scientific article published on 5 October 2016

Drug discovery and development with plant-derived compounds.

scientific article published on January 2008

Editorial--Planta Medica abstract issue

scientific article published on 01 March 2014

Effects of Leuzea carthamoides on human breast adenocarcinoma MCF-7 cells determined by gene expression profiling and functional assays

scientific article

Effects of a Multicomponent Herbal Extract on the Course of Subclinical Ketosis in Dairy Cows - a Blinded Placebo-controlled Field-study

scientific article published on 01 October 2020

Effects of solvent composition on molecular ion response in electrospray mass spectrometry: Investigation of the ionization processes

scientific article published in 1995

Efficacy of a Juncus effusus extract on grapevine and apple plants against Plasmopara viticola and Venturia inaequalis, and identification of the major active constituent

scientific article published on 30 November 2015

Efficacy of a Magnolia officinalis bark extract against grapevine downy mildew and apple scab under controlled and field conditions

scientific article published on 22 August 2018

Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives

scientific article

Epilepsy in the Renaissance: A survey of remedies from 16th and 17th century German herbals

scientific article published on June 16, 2012

Ethnobotanical survey on wild alpine food plants in Lower and Central Valais (Switzerland).

scientific article published on 20 November 2013

Ethnoveterinary contemporary knowledge of farmers in pre-alpine and alpine regions of the Swiss cantons of Bern and Lucerne compared to ancient and recent literature - Is there a tradition?

scientific article published on 17 December 2018

Ethnoveterinary herbal remedies used by farmers in four north-eastern Swiss cantons (St. Gallen, Thurgau, Appenzell Innerrhoden and Appenzell Ausserrhoden).

scientific article

Ethnoveterinary knowledge of farmers in bilingual regions of Switzerland - is there potential to extend veterinary options to reduce antimicrobial use?

scientific article published on 26 August 2019

Eudesmane Sesquiterpenes from Verbesina lanata with Inhibitory Activity against Grapevine Downy Mildew.

scientific article

Extraction and analysis of intact glucosinolates--a validated pressurized liquid extraction/liquid chromatography-mass spectrometry protocol for Isatis tinctoria, and qualitative analysis of other cruciferous plants

scientific article published on 17 August 2007

Farinosones A-C, neurotrophic alkaloidal metabolites from the entomogenous deuteromycete Paecilomyces farinosus

scientific article

Flash chromatography on cartridges for the separation of plant extracts: rules for the selection of chromatographic conditions and comparison with medium pressure liquid chromatography

scientific article published on 27 August 2010

Flavans and A-type proanthocyanidins from Prunus prostrata

Flavone 8-C-Glycosides from Haberlea rhodopensisFriv. (Gesneriaceae)

scientific article published on 21 January 2011

Flavone C-Glycosides from Isatis tinctoria Leaves

Flavonoids from Ericameria nauseosa inhibiting PI3K/AKT pathway in human melanoma cells

scientific article published in December 2022

Flavonol glycosides from Monnina sylvatica

scientific article published on 01 January 1991

Flavonol glycosides from Securidaca diversifolia

GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding

scientific article published on 2 December 2017

GABAA receptor modulation by piperine and a non-TRPV1 activating derivative

scientific article published on 25 April 2013

Gastroprotective effects of hydroethanolic root extract of Arrabidaea brachypoda: Evidences of cytoprotection and isolation of unusual glycosylated polyphenols

scientific article published on 21 December 2016

Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7.

scientific article

Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure

scientific article

Glucosinolate pattern in Isatis tinctoria and I. indigotica seeds

scientific article published on 6 June 2008

Glycosidic Constituents of some European Polygala Species

scientific article published on 11 March 2005

Gram-scale purification of dehydroevodiamine from Evodia rutaecarpa fruits, and a procedure for selective removal of quaternary indoloquinazoline alkaloids from Evodia extracts

scientific article published on 19 February 2014

HPLC Analysis of the flavonoids in pharmaceutical preparations from canadian goldenrod (Solidago canadensis)

scientific article published in 2002

HPLC based activity profiling for 5-lipoxygenase inhibitory activity in Isatis tinctoria leaf extracts

scientific article

HPLC-Based Activity Profiling for Antiprotozoal Compounds in Croton gratissimus and Cuscuta hyalina

scientific article published on 14 August 2020

HPLC-Based Activity Profiling for Antiprotozoal Compounds in the Endemic Iranian Medicinal Plant Helichrysum oocephalum

scientific article published on 27 March 2019

HPLC-Based Activity Profiling for GABAA Receptor Modulators in Extracts: Validation of an Approach Utilizing a Larval Zebrafish Locomotor Assay

scientific article published on 9 May 2017

HPLC-Based Activity Profiling for GABAA Receptor Modulators in Searsia pyroides Using a Larval Zebrafish Locomotor Assay

scientific article

HPLC-Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana

scientific article published on 29 April 2015

HPLC-based Activity Profiling - Discovery of Sanggenons as GABAAReceptor Modulators in the Traditional Chinese Drug Sang bai pi (Morus albaRoot Bark)

scientific article published on January 31, 2012

HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes

scientific article

HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium

scientific article published on April 2010

HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root)

scientific article published on January 5, 2011

HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus

scientific article published on 26 February 2014

HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant Carica papaya L.

scientific article

HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products - principles and recent examples

scholarly article by Matthias Hamburger published December 2019 in Pharmaceutical Biology

HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes

scientific article published on December 13, 2010

HPLC-based activity profiling of Salvia miltiorrhiza for MAO A and iNOS inhibitory activities

scientific article published in October 2004

HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site

scientific article

HPLC-based bioactivity profiling of plant extracts: a kinetic assay for the identification of monoamine oxidase-A inhibitors using human recombinant monoamine oxidase-A.

scientific article published in November 2004

HPLC-profiling for antiplasmodial compounds—3-Methoxycarpachromene from Pistacia atlantica

article published in 2009

High-Content Screening Pipeline for Natural Products Targeting Oncogenic Signaling in Melanoma

Highlights of Analytical Sciences in Switzerland

scientific article published on 01 March 2019

Honeybush Extracts (Cyclopia spp.) Rescue Mitochondrial Functions and Bioenergetics against Oxidative Injury

scientific article published on 07 August 2020

Hydrangenone, a new isoprenoid with an unprecedented skeleton from Salvia hydrangea

scientific article published on 01 December 2011

Hydroxycinnamic acid esters from Polygala chamaebuxus

scientific article published on 25 July 2002

Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens.

scientific article published on 3 July 2017

Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice.

scientific article published on 27 July 2011

Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations

scientific article

Identification of Plant-derived Alkaloids with Therapeutic Potential for Myotonic Dystrophy Type I

scientific article

Identification of TLC markers and quantification by HPLC-MS of various constituents in noni fruit powder and commercial noni-derived products

scientific article

Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator

scientific article published on 6 September 2014

Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators

scientific article published on 10 January 2014

Identification of two new phenathrenones and a saponin as antiprotozoal constituents of Drypetes gerrardii

Immunosuppressive Activity of Artemisia argyi Extract and Isolated Compounds

scientific article published on 08 April 2020

In vitro blood-brain barrier permeability predictions for GABAA receptor modulating piperine analogs.

scientific article published on 24 March 2016

In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.

scientific article

In vitro screening of traditional South African malaria remedies against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum

scientific article published on 16 March 2011

Inhibition of porcine detrusor contractility by the flavonoid fraction of Bryophyllum pinnatum--a potential phytotherapeutic drug for the treatment of the overactive bladder syndrome

scientific article

Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities

scientific article

Inhibitory activity of tryptanthrin on prostaglandin and leukotriene synthesis

scientific article published in October 2002

Isoflavones and xanthones fromPolygala virgata

scientific article published on 25 July 2002

Isolation and Fast Selective Determination of Nor-abietanoid Diterpenoids from Perovskia atriplicifolia Roots Using LC-ESI-MS/MS with Multiple Reaction Monitoring.

scientific article

Isolation of a flavone from Polygala stenopetala

scientific article published on 01 July 1999

Juice of Bryophyllum pinnatum (Lam.) inhibits oxytocin-induced increase of the intracellular calcium concentration in human myometrial cells.

scientific article published on 9 April 2010

Labdane Diterpenoids from Salvia leriifolia: Absolute Configuration, Antimicrobial and Cytotoxic Activities

scientific article published on 9 June 2016

Labdane and Clerodane Diterpenoids from Colophospermum mopane

scientific article published on 07 October 2015

Leaf press juice from Bryophyllum pinnatum (Lamarck) Oken induces myometrial relaxation

scientific article published on July 30, 2011

Library-based discovery and characterization of daphnane diterpenes as potent and selective HIV inhibitors in Daphne gnidium.

scientific article

Library-based discovery of DYRK1A/CLK1 inhibitors from natural product extracts

scientific article

Lignans, Amides, and Saponins from Haplophyllum tuberculatum and Their Antiprotozoal Activity

scientific article published on 19 June 2020

Malaria in the renaissance: Remedies from European herbals from the 16th and 17th century

scientific article published on November 5, 2010

Manoyloxide Sesterterpenoids from Salvia mirzayanii

scientific article published in April 2014

Mechanism of chemical degradation and determination of solubility by kinetic modeling of the highly unstable sesquiterpene lactone nobilin in different media

scientific article

Medicinal herbs for the treatment of rheumatic disorders--a survey of European herbals from the 16th and 17th century

scientific article

Metabolite Profile and Antiproliferative Effects in HaCaT Cells of a Salix reticulata Extract

scientific article published on 27 April 2017

Metabolite Profiling of the Leaves of the Brazilian Folk MedicineSideroxylon obtusifolium

scientific article published on February 9, 2012

Method development spurs scientific progress

scientific article published on 01 August 2005

Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways

scientific article published in November 2004

Militarinone A, a neurotrophic pyridone alkaloid from Paecilomyces militaris

scientific article published on 01 January 2002

Mining Sudanese Medicinal Plants for Antiprotozoal Agents

scientific article published on 09 June 2020

Molecular mechanisms of endocrine and metabolic disruption: An in silico study on antitrypanosomal natural products and some derivatives

scientific article published on 15 April 2016

Molluscicidal milliamines from Euphorbia milii var. hislopii

scientific article published on 25 July 2002

Morinda citrifolia (Noni) fruit--phytochemistry, pharmacology, safety

scientific article published on 7 February 2007

NMR-Based Metabolomic Study on Isatis tinctoria: Comparison of Different Accessions, Harvesting Dates, and the Effect of Repeated Harvesting

scientific article published on 6 May 2015

Natural Products in Drug Discovery - Concepts and Approaches for Tracking Bioactivity

scientific article published in 2006

Natural products as potential human ether-a-go-go-related gene channel inhibitors - outcomes from a screening of widely used herbal medicines and edible plants

scientific article published on 4 August 2014

Natural products as potential human ether-a-go-go-related gene channel inhibitors - screening of plant-derived alkaloids

scientific article published on 25 June 2014

Neurotoxic Sesquiterpene Lactones from the Yellow Star ThistleCentaurea solstitialis: Large-Scale Isolation and Biological Activity

scientific article published on 16 January 2007

Neurotoxic Sesquiterpenoids from the Yellow Star ThistleCentaurea solstitialis L. (Asteraceae)

scientific article published in 1991

New Acylated Flavonol Glycosides and a Phenolic Profile of Pritzelago alpina, a Forgotten Edible Alpine Plant

scientific article published on 01 February 2016

New Saponins and a Prosapogenin fromPolygala chamaebuxus L

scientific article published on 26 December 2004

New Secoiridoid Glucoside, and a Metabolite Profile of Scabiosa lucida

scientific article published on 01 July 2016

New Steroidal Glycosides from Balanites aegyptiaca

New approaches in analyzing the pharmacological properties of herbal extracts

scientific article published on January 2007

New coumarin-hemiterpene ether glucosides and a structurally related phenylpropanoic acid derivative from Artemisia armeniaca.

scientific article published on October 2010

New ursane triterpenoids from Salvia urmiensis Bunge: Absolute configuration and anti-proliferative activity

scientific article

Noniosides E - H, new trisaccharide fatty acid esters from the fruit of Morinda citrifolia (Noni)

scientific article published on 18 October 2006

Novel Acetogenins from the Leaves of Annona purpurea

Novel Prenylated Xanthones fromGarcinia gerrardii HARVEY

scientific article published on 26 December 2004

Novel tetramic acids and pyridone alkaloids, militarinones B, C, and D, from the insect pathogenic fungus Paecilomyces militaris

scientific article published in March 2003

Occurrence of stable foam in the upper Rhine River caused by plant-derived surfactants

scientific article published on 01 August 2002

Oleanane Saponins and Glycerogalactolipids from the Leaves of Guapira graciliflora

scientific article published on 16 June 2010

Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin

scientific article published on 19 April 2016

Pharmacokinetics of dietary kaempferol and its metabolite 4-hydroxyphenylacetic acid in rats

scientific article published on 31 October 2016

Pharmacokinetics of valerenic acid in rats after intravenous and oral administrations

scientific article published on 12 March 2012

Pharmacokinetics of α-mangostin in rats after intravenous and oral application.

scientific article published on 20 January 2011

Phylobioactive hotspots in plant resources used to treat Chagas disease

scientific article published on 19 March 2021

Phyteumosides A and B: New Saponins with Unique Triterpenoid Aglycons from Phyteuma orbiculare L

scientific article published on February 15, 2011

Phytochemical Study of Salvia leriifolia Roots: Rearranged Abietane Diterpenoids with Antiprotozoal Activity

scientific article published on 13 June 2018

Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators

scientific article published on 3 September 2013

Plant and natural product based homemade remedies manufactured and used by farmers of six central Swiss cantons to treat livestock

article

Plant anticancer agents, XLIII. (E,E)-7, 12-dioxo-octadeca-8, 10-dien-1-oic acid (ostopanic acid), a cytotoxic fatty acid from Ostodes Paniculata

scientific article published on March 1987

Planta Medica Letters

Plants traditionally used in age related brain disorders--a survey of ethnobotanical literature

scientific article

Positive GABAA Receptor Modulators from Acorus calamus and Structural Analysis of (+)-Dioxosarcoguaiacol by 1D and 2D NMR and Molecular Modeling

scientific article published on May 12, 2011

Potential of Bryophyllum pinnatum as a Detrusor Relaxant: An in Vitro Exploratory Study.

scientific article published on 24 April 2017

Pressurized liquid extraction of medicinal plants

scientific article published on 01 April 1999

Prevention of experimentally induced irritant contact dermatitis by extracts of Isatis tinctoria compared to pure tryptanthrin and its impact on UVB-induced erythema

scientific article

Profiling of isoflavonoids in Iris germanica rhizome extracts by microprobe NMR and HPLC-PDA-MS analysis

scientific article published on June 25, 2011

Promotion of cell death or neurite outgrowth in PC-12 and N2a cells by the fungal alkaloid militarinone A depends on basal expression of p53.

scientific article

Pseudolaric add B: NMR spectroscopy, conformation and biological activity

scientific article published on 01 December 1988

Purified compounds from marine organism sea pen induce apoptosis in human breast cancer cell MDA-MB-231 and cervical cancer cell Hela

scientific article published on 25 March 2020

Quantification of Bufadienolides in Bryophyllum pinnatum Leaves and Manufactured Products by UHPLC-ESIMS/MS

scientific article published on 01 July 2015

Quantification of active principles and pigments in leaf extracts of Isatis tinctoria by HPLC/UV/MS

scientific article published on 19 January 2007

Quantification of the antiplasmodial alkaloid carpaine in papaya (Carica papaya) leaves

scientific article

Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil.

scientific article

Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose seeds

scientific article published on 01 September 2006

Quantitative determination of the dual COX-2/5-LOX inhibitor tryptanthrin in Isatis tinctoria by ESI-LC-MS.

scientific article published in February 2002

Radical scavengers from the entomogenous deuteromycete Beauveria amorpha

scientific article published in January 2002

Rapid analysis of nucleotide-activated sugars by high-performance liquid chromatography coupled with diode-array detection, electrospray ionization mass spectrometry and nuclear magnetic resonance

scientific article published in April 2004

Recovery of polyphenols from rose oil distillation wastewater using adsorption resins--a pilot study

scientific article

Regulation of secretases by all-trans-retinoic acid

scientific article

Renaissance remedies: Antiplasmodial protostane triterpenoids from Alisma plantago-aquatica L. (Alismataceae)

scientific article published on 24 February 2011

Saffron Flower Extract Promotes Scratch Wound Closure of Keratinocytes and Enhances VEGF Production

scientific article published on 20 April 2017

Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants

scientific article

Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds.

scientific article published on 11 December 2014

Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities

scientific article published on 15 October 2014

Search for Bitter Principles in Chironia Species by LC-MS and Isolation of a New Secoiridoid Diglycoside from Chironia krebsii

Search for Chlorinated Sesquiterpenes in the Neurotoxic Thistle<i>Centaurea solstitialis</i>

scientific article published in 1992

Search for New Drugs of Plant Origin

Search for chlorinated sesquiterpene lactones in the neurotoxic thistle Centaurea solstitialis by liquid chromatography-mass spectrometry, and model studies on their possible artifactual formation

scientific article

Seasonal changes and effect of harvest on glucosinolates in Isatis leaves

scientific article published on 01 April 2008

Seco-ursane-type Triterpenoids from Salvia urmiensis with Apoptosis-inducing Activity

scientific article published on 07 August 2015

Secondary Metabolites in Allergic Plant Pollen Samples Modulate Afferent Neurons and Murine Tracheal Rings.

scientific article

Securigenin glycosides as hypoglycemic principles of Securigera securidaca seeds

scientific article

Separation and detection of all phosphoinositide isomers by ESI-MS

scientific article published on 30 March 2010

Sesquiterpene Lactones from Artemisia argyi: Absolute Configuration and Immunosuppressant Activity

scientific article published on 05 June 2019

Sesquiterpene Lactones with Astrodaucane Skeleton from Astrodaucus orientalis

scientific article published on 09 April 2022

Sinapic acid esters from Polygala virgata

scientific article published on 01 February 1993

Single dose pharmacokinetics of intravenous 3,4-dihydroxyphenylacetic acid and 3-hydroxyphenylacetic acid in rats

scientific article published on 22 February 2020

Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: an observational study.

scientific article published on 25 December 2013

Society for Medicinal Plant and Natural Product Research: Bionorica Phytoneering Award 2017, Egon-Stahl-Award in Gold 2017, Egon-Stahl-Award in Silver 2017, 2017 Dr. Willmar Schwabe Research Scholarship for Young Scientists

scientific article

Special Issue dedicated to Prof. Dr. Dres. h. c. mult. Kurt Hostettmann

scientific article published on 20 July 2016

Special issue in honor of Professor Otto Sticher.

scientific article published on 24 February 2014

Structure-Elucidating Total Synthesis of the (Polyenoyl)tetramic Acid Militarinone C§

scientific article published on 19 March 2020

Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products.

scientific article published on 21 March 2014

Supercritical carbon dioxide extraction of marigold at high pressures: comparison of analytical and pilot-scale extraction

scientific article

Swiss ethnoveterinary knowledge on medicinal plants - a within-country comparison of Italian speaking regions with north-western German speaking regions

scientific article published on 03 January 2017

Telemetry as a Tool to Measure Sedative Effects of a Valerian Root Extract and Its Single Constituents in Mice

scientific article published on December 10, 2010

Tensioactive Compounds from the Aquatic Plant Ranunculus fluitans L. (Ranunculaceae)

scientific article published on 25 August 2002

Terpenoids and phenolics of Micromeria persica

scientific article published on 16 April 2019

The Dual Edema-Preventing Molecular Mechanism of the Crataegus Extract WS 1442 Can Be Assigned to Distinct Phytochemical Fractions

scientific article published on 22 December 2016

The content of indigo precursors in Isatis tinctoria leaves--a comparative study of selected accessions and post-harvest treatments

scientific article published on 01 December 2004

The elusive indigo precursors in woad (Isatis tinctoria L.)--identification of the major indigo precursor, isatan A, and a structure revision of isatan B

scientific article published on 01 January 2004

Thyroid Hormones Are Transport Substrates and Transcriptional Regulators of Organic Anion Transporting Polypeptide 2B1

scientific article published on 07 May 2018

Total Synthesis and Neuritotrophic Activity of Farinosone C and Derivatives

scientific article published on 01 August 2009

Toxic effects of solstitialin a 13-acetate and cynaropicrin from Centaurea solstitialis L. (asteraceae) in cell cultures of foetal rat brain

scientific article published on March 1, 1992

Toxic inhibition of smooth muscle contractility by plant-derived sesquiterpenes caused by their chemically reactive alpha-methylenebutyrolactone functions

scientific article published on May 1994

Traditional use of herbal remedies in livestock by farmers in 3 Swiss cantons (Aargau, Zurich, Schaffhausen).

scientific article published on 15 June 2012

Treatment of organic livestock with medicinal plants: a systematic review of European ethnoveterinary research.

scientific article

Triterpenoids with rare carbon skeletons from Salvia hydrangea: antiprotozoal activity and absolute configurations

scientific article published on 03 October 2011

Tryptanthrin content in Isatis tinctoria leaves--a comparative study of selected strains and post-harvest treatments

scientific article published on 01 July 2004

Two new flavonol glycosides and a metabolite profile of Bryophyllum pinnatum, a phytotherapeutic used in obstetrics and gynaecology.

scientific article published on 26 September 2013

Tyrosinase inhibitory constituents from a polyphenol enriched fraction of rose oil distillation wastewater

scientific article published on 16 November 2015

Ultraviolet a induces generation of squalene monohydroperoxide isomers in human sebum and skin surface lipids in vitro and in vivo

scientific article

Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies

scientific article

Validation of an immortalized human (hBMEC) in vitro blood-brain barrier model

scientific article published on 21 January 2016

Wound Healing Potential of Chlorogenic Acid and Myricetin-3-O-β-Rhamnoside Isolated from Parrotia persica.

scientific article published on 8 September 2017

Xanthones from Polygala nyikensis

scientific article published on 25 July 2002

Xanthones fromChironia krebsii

Zwischen Empirie und Evidenz - (Re)Aktivierung der Veterinärphytotherapie

scientific article published on 04 July 2014

hERG Channel Inhibitors in Extracts of Coptidis Rhizoma

scientific article published on March 16, 2011

hERG Channel Inhibitory Daphnane Diterpenoid Orthoesters and Polycephalones A and B with Unprecedented Skeletons from Gnidia polycephala

scientific article published on 19 June 2015