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List of works by José M. Padrón

A Focused Library of NO-Donor Compounds with Potent Antiproliferative Activity Based on Green Multicomponent Reactions

scientific article published on 23 August 2019

A green multicomponent synthesis of tocopherol analogues with antiproliferative activities.

scientific article

A modular approach to trim cellular targets in anticancer drug discovery

scientific article published on 22 September 2011

Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines.

scientific article

Acanthamoeba castellanii: A new high-throughput method for drug screening in vitro.

scientific article

Anti-inflammatory activity of a novel family of aryl ureas compounds in an endotoxin-induced airway epithelial cell injury model

scientific article

Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia

scientific article published in January 2018

Antiproliferative activity in HL60 cells by tetrasubstituted pyrroles: a structure-activity relationship study

scientific article

Antiproliferative activity of dmoPTA-Ru(II) complexes against human solid tumor cells

scientific article published on 12 June 2011

Antiproliferative activity of epi-cercosporin in human solid tumor cell lines

scientific article published on February 1, 2013

Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines

scientific article

Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol

scientific article published on 23 February 2010

Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations.

scientific article

Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids.

scientific article published on 30 July 2015

Antiproliferative and antibacterial activity of extracts of <i>Ganoderma</i> strains grown in vitro

scientific article published on 05 May 2021

Antiproliferative and quinone reductase-inducing activities of withanolides derivatives

scientific article

Antiproliferative effect of extract from endophytic fungus Curvularia trifolii isolated from the "Veracruz Reef System" in Mexico.

scientific article published on 22 April 2016

Antiproliferative effects of novel aliphatic acetogenin analogs against aggressive solid tumor cell lines.

scientific article published on March 2011

Antiproliferative evaluation of N-sulfonyl-2-alkyl-six membered azacycles. A QSAR study.

scientific article published on January 2014

Antiproliferative potential of 3β,5α,6β,7α-tetrahydroxyergosta-8(14),22-diene produced by Acremonium persicinum isolated from an alkaline crater lake in Puebla, Mexico

scientific article published on 26 September 2019

Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa ⬇️

scientific article published on 23 July 2010

Belizeanolide, a cytotoxic macrolide from the dinoflagellate Prorocentrum belizeanum.

scientific article

Biological Activities of Extracts from Aerial Parts of Epling Ex Munz

article

Biomimetic synthesis of two salmahyrtisanes: salmahyrtisol A and hippospongide A.

scientific article

CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells

scientific article published on 08 June 2019

Chalcogen-containing phenolics as antiproliferative agents.

scientific article published on 5 February 2018

Correction: Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model.

scientific article published on 13 November 2012

Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex

scientific article published on 21 July 2010

Cytotoxic bioactivity of some phenylpropanoic acid derivatives

scientific article published on October 1, 2012

Cytotoxic effects of C-glycosides in HOS and HeLa cell lines.

scientific article published on 25 April 2007

Cytotoxicity of sphingoid marine compound analogs in mono- and multilayered solid tumor cell cultures

scientific article published on May 2006

DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells.

scientific article published on 11 May 2017

Derivatives of grindelic acid: from a non-active natural diterpene to synthetic antitumor derivatives.

scientific article

Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2'-2'-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000.

scientific article published on August 2004

Dienamine and Friedel-Crafts one-pot synthesis, and antitumor evaluation of diheteroarylalkanals.

scientific article published on 23 April 2015

Direct stereoselective synthesis of enantiomerically pure anti-β-amino alcohols

scientific article published on 10 April 2014

Diversity and bioactivity of sediment-associated fungi from a mangrove forest in Mexico with different conservation conditions

scientific article published in 2023

Effect of electronic and steric properties of 8-substituted quinolines in gold(III) complexes: Synthesis, electrochemistry, stability, interactions and antiproliferative studies.

scientific article published on 17 June 2017

Efficient synthesis and biological evaluation of new benzopyran-annulated pyrano[2,3-c]pyrazole derivatives

scientific article published on 14 March 2017

Enantioselective transport by a steroidal guanidinium receptor.

scientific article

Enhancement of antiproliferative activity by molecular simplification of catalpol

scientific article published on March 2010

Enhancement of the antiproliferative activity of [RuCp(PPh3)2(dmoPTA-1κP)]+via its coordination to one {CoCl2} unit: synthesis, crystal structure and properties of [RuCp(PPh3)2-μ-dmoPTA-1κP:2κ2N,N'-CoCl2](OTf)·0.25H2O.

scientific article published on 15 June 2017

Expanding the synthesis of new trans-sulfonamide platinum complexes: cytotoxicity, SAR, fluorescent cell assays and stability studies.

scientific article published on 8 February 2013

Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates

scientific article published in September 2000

Gamma-lactones alpha,beta- and beta,gamma-fused to carbocycles as novel antiproliferative drugs.

scientific article published on 29 August 2008

Heterometallic platinum(ii) compounds with β-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity ⬇️

scientific article published on October 25, 2011

Highly selective hydroformylation of the cinchona alkaloids

scientific article published in July 2002

Hydroxyl alkyl ammonium ionic liquid assisted green and one-pot regioselective access to functionalized pyrazolodihydropyridine core and their pharmacological evaluation

scientific article published on 19 January 2019

In vitro synergistic interaction between DTA0100 and radiation in human cancer cell lines

scientific article published on 01 October 2012

Influence of the configurational pattern of sp(2)-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties.

scientific article published on 21 January 2016

Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates.

scientific article

Koanolides B-D, new sesquiterpene lactones from Koanophyllon gibbosum

scientific article published on 29 November 2021

Masked Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance

scientific article published on 31 October 2020

MicroRNAs Targeting MYC Expression: Trace of Hope for Pancreatic Cancer Therapy. A Systematic Review

scientific article published on 01 April 2020

Mitotic arrest induced by a novel family of DNA topoisomerase II inhibitors.

scientific article

Molecular docking studies of the interaction between propargylic enol ethers and human DNA topoisomerase IIα.

scientific article

Molecular simplification in bioactive molecules: formal synthesis of (+)-muconin.

scientific article published on March 2006

New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation

scientific article published on 24 May 2019

New selenosteroids as antiproliferative agents.

scientific article published on 2 June 2017

New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents

scientific article published on 27 June 2017

Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol.

scientific article published on 3 December 2006

Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand.

scientific article published on 14 August 2013

Novel synthesis of steroidal oximes and lactams and their biological evaluation as antiproliferative agents

scientific article

One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity

scientific article published on 24 November 2020

One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters

scientific article published on 12 May 2016

Phenolic thio- and selenosemicarbazones as multi-target drugs.

scientific article

Phytochemical Study of Senecio volckmannii Assisted by CASE-3D with Residual Dipolar Couplings and Isotropic H/C NMR Chemical Shifts

scientific article published on 25 October 2018

Pinnatifidenyne-Derived Ethynyl Oxirane Acetogenins from Laurencia viridis

scientific article published on 29 December 2017

Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action

scientific article published on 20 March 2019

QSAR on antiproliferative naphthoquinones based on a conformation-independent approach

scientific article published on 26 February 2014

Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured

scientific article

Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A.

scientific article published on 20 October 2015

Samarium(II) promoted stereoselective synthesis of antiproliferative cis-beta-alkoxy-gamma-alkyl-gamma-lactones

scientific article published on 6 October 2006

Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea

scientific article published on 09 May 2019

Selective cell kill of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures.

scientific article published on June 1999

Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and Studies

scientific article published on 03 July 2018

Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations

scientific article published on 27 June 2019

Selenoureido-iminosugars: A new family of multitarget drugs.

scientific article

Sphingolipids in anticancer therapy

scientific article

Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane).

scientific article published on 27 July 2016

Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies

scientific article published on 06 March 2019

Synthesis and Evaluation of Pyrimidine Steroids as Antiproliferative Agents

scientific article published on 12 October 2019

Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans.

scientific article published on 6 September 2006

Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation.

scientific article published on 27 October 2006

Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides.

scientific article

Synthesis and antiproliferative activity of glutamic acid-based dipeptides

scientific article published on 22 April 2015

Synthesis and antiproliferative activity of new 2-glyco-3-nitro-2H-chromenes

scientific article published on 09 March 2019

Synthesis and antiproliferative activity of novel sugiol beta-amino alcohol analogs

scientific article published on 7 July 2006

Synthesis and antiproliferative activity of peracetylated 2-amino-1,2-dideoxy-1-nitro-d-glycero-l-manno and d-glycero-d-talo heptitols

scientific article published on 23 September 2016

Synthesis and antiproliferative activity of the heterobimetallic complexes [RuClCp(PPh₃)-μ-dmoPTA-1κP:2κ²N,N'-MCl₂] (M = Co, Ni, Zn; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane).

scientific article published on August 2013

Synthesis and antiproliferative activity of α-branched α,β-unsaturated ketones

scientific article published on 22 October 2013

Synthesis and bioactivity of Luffarin I.

scientific article published on 20 April 2015

Synthesis and biological activity of polyalthenol and pentacyclindole analogues.

scientific article published on 25 December 2013

Synthesis and biological evaluation of crown ether acyl derivatives.

scientific article published on 29 September 2016

Synthesis and identification of unprecedented selective inhibitors of CK1ε.

scientific article published on 14 April 2015

Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl d-ribofuranosides

scientific article

Synthesis and in vitro cytotoxicity of long chain 2-amino alcohols and 1,2-diamines

scientific article published on 01 July 2001

Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues

scientific article

Synthesis of Luffarin L and 16-epi-Luffarin L Using a Temporary Silicon-Tethered Ring-Closing Metathesis Reaction

scientific article published on 29 May 2015

Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines.

scientific article published on 27 September 2016

Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies

scientific article published on 08 August 2019

Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs.

scientific article published on 2 November 2017

Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols

scientific article published on 01 March 1999

Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors

scientific article published on 22 July 2019

Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines

scientific article

The multilayered postconfluent cell culture as a model for drug screening

scientific article

The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells.

scientific article published in August 2005

Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids

scientific article published on 08 August 2019

Total synthesis of (+)-herboxidiene/GEX 1A.

scientific article published on 3 February 2017

Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors

scientific article published on 01 December 2021

ent-Labdane Diterpenoids from the Aerial Parts of Eupatorium obtusissmum.

scientific article

β-Lapachone analogs with enhanced antiproliferative activity

scientific article published on 19 April 2012

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