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List of works by Philip J. Coates

A bromocriptine-responsive corticotroph adenoma secreting alpha-MSH in a patient with Cushing's disease

scientific article published on 01 February 1988

AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway

scientific article published on 17 December 2015

Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer.

scientific article published on 8 November 2016

Anal cancer and human papillomaviruses

scientific article published on 01 December 1989

Assessment of cell proliferation in pathology--what next?

scientific article published on February 1995

At last, a predictive and prognostic marker for radiotherapy?

scientific article published on 11 May 2010

Autoantibodies and decreased expression of the transcription factor ELF-3 together with increased chemokine pathways support an autoimmune phenotype and altered differentiation in lichen planus located in oral mucosa.

scientific article published on 8 November 2012

Bystander-type effects mediated by long-lived inflammatory signaling in irradiated bone marrow

scientific article published on 09 December 2011

C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

scientific article

Cell and tissue responses to genotoxic stress.

scientific article

Characterization of integrin chains in normal and neoplastic human pancreas

scientific article published on 01 September 1991

Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry

scientific article published on 26 July 2013

Characterization of the expression pattern of p63 alpha and delta Np63 alpha in benign and malignant oral epithelial lesions

scientific article

Chromosomal instability in unirradiated hemaopoietic cells induced by macrophages exposed in vivo to ionizing radiation

scientific article published in October 2008

Chromosomal instability in unirradiated hemopoietic cells resulting from a delayed in vivo bystander effect of gamma radiation

scientific article published on 01 July 2005

Comments on "Transcriptional profiling of oral squamous cell carcinoma using formalin-fixed paraffin-embedded samples" by Saleh et al., Oral Oncol 46 (2010) 379-386

scientific article published on 24 July 2010

Copy number variation: a prognostic marker for young patients with squamous cell carcinoma of the oral tongue

scientific article published on 02 November 2018

Correlation between Reversal of DNA Methylation and Clinical Symptoms in Psoriatic Epidermis Following Narrow-Band UVB Phototherapy

scientific article

Decreased expression of p63 in oral lichen planus and graft-vs.-host disease associated with oral inflammation

scientific article published in January 2006

Decreased expression of the p63 related proteins beta-catenin, E-cadherin and EGFR in oral lichen planus

scientific article published on 23 October 2007

DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck

scientific article

Detecting and quantifying apoptosis in tissue sections

scientific article published on 01 January 2004

Detection of Epstein-Barr virus in Reed-Sternberg cells of Hodgkin's disease arising in children

scientific article published in January 1993

Detection of antibodies against p63 and p73 isoforms in sera from patients diagnosed with oral lichen planus

scientific article published on 01 February 2007

Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity

scientific article published on 28 July 2011

Differential contextual responses of normal human breast epithelium to ionizing radiation in a mouse xenograft model

scientific article published on 16 November 2010

Differential expression of p63 isoforms in normal tissues and neoplastic cells

scientific article published on December 2002

Differential expression of p73alpha in normal ectocervical epithelium, cervical intraepithelial neoplasia, and invasive squamous cell carcinoma

scientific article published in October 2003

Differential post-translational modification of the tumour suppressor proteins Rb and p53 modulate the rates of radiation-induced apoptosis in vivo

scientific article published on 01 June 2001

Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry

scientific article published on 01 November 2005

Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma.

scientific article

Dysregulation of TAp63 mRNA and protein levels in psoriasis

scientific article published on 01 January 2006

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6.

scientific article published on January 2013

Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis

scientific article published on 01 June 2011

Effects of an aromatase inhibitor on thymus and kidney and on oestrogen receptors in female MRL/MP-lpr/lpr mice

scientific article published on 01 August 1993

Endocrine cells of the human gastrointestinal tract have no proliferative capacity

scientific article published on 01 June 1995

Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites

scientific article published on 30 August 2016

Erratum to: ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer.

scientific article

Ethnicity based variation in expression of E-cadherin in patients with squamous cell carcinoma of the oral tongue

scientific article published on 18 September 2018

Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial

scientific article published on 15 February 2015

Evidence that circulating proteins are more promising than miRNAs for identification of patients with squamous cell carcinoma of the tongue.

scientific article published on 30 September 2017

Exclusion of p63 as a candidate gene for autosomal-dominant amelogenesis imperfecta.

scientific article

Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue

scientific article

Expression of p16 in squamous cell carcinoma of the mobile tongue is independent of HPV infection despite presence of the HPV-receptor syndecan-1

scientific article published on 9 June 2015

Expression of p53 isoforms in squamous cell carcinoma of the head and neck

scientific article published on 9 January 2007

Fen1 expression: a novel marker for cell proliferation

scientific article published on November 1998

Gene expression changes in tumor free tongue tissue adjacent to tongue squamous cell carcinoma.

scientific article published on 27 December 2016

Genes involved in epithelial differentiation and development are differentially expressed in oral and genital lichen planus epithelium compared to normal epithelium

scientific article published on 01 September 2014

Heterogeneity of p53-pathway Protein Expression in Chemosensitive Chronic Lymphocytic Leukemia: A Pilot Study ⬇️

scientific article published on August 24, 2012

High expression of p63 is correlated to poor prognosis in squamous cell carcinoma of the tongue.

scientific article published on 23 April 2013

Immunocytochemical p63 expression discriminates between primary cutaneous follicle centre cell and diffuse large B cell lymphoma-leg type, and is of the TAp63 isoform

scientific article published on 2 September 2015

In Brief: cell senescence ⬇️

scientific article published on 01 July 2013

In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

scientific article published on 01 May 1993

In vivo interactions between ionizing radiation, inflammation and chemical carcinogens identified by increased DNA damage responses

scientific article published on 30 March 2012

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

scientific article published on 25 August 2016

Increased expression of Smad proteins, and in particular Smad3, in oral lichen planus compared to normal oral mucosa

scientific article published on 2 July 2010

Indirect macrophage responses to ionizing radiation: implications for genotype-dependent bystander signaling

scientific article

Induction of endogenous beta-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice

scientific article published on 01 October 2001

Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects?

scientific article published in October 2001

Interactions of apoptotic cells with macrophages in radiation-induced bystander signaling

scientific article published on 13 December 2012

Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition

scientific article published in PLoS ONE

Lack of correlation of stem cell markers in breast cancer stem cells.

scientific article published on 27 February 2014

Lack of nontargeted effects in murine bone marrow after low-dose in vivo X irradiation

scientific article published on 28 December 2010

Localization of cytochrome P-450 gene expression in normal and diseased human liver by in situ hybridization of wax-embedded archival material.

scientific article published on September 1992

Markers of senescence?

scientific article published on 01 April 2002

Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status.

scientific article published on 21 May 2014

No evidence for the presence of Epstein-Barr virus in squamous cell carcinoma of the mobile tongue

scientific article published on 19 September 2017

Ongoing activation of p53 pathway responses is a long-term consequence of radiation exposure in vivo and associates with altered macrophage activities

scientific article published in April 2008

Oxidation reduction is a key process for successful treatment of psoriasis by narrow-band UVB phototherapy

scientific article

Patients with high c-MYC-expressing squamous cell carcinomas of the tongue show better survival than those with low- and medium-expressing tumours

scientific article

Persistence of Epstein-Barr virus in Reed-Sternberg cells throughout the course of Hodgkin's disease.

scientific article

Phenformin as prophylaxis and therapy in breast cancer xenografts

scientific article published on 23 February 2012

Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis.

scientific article published on 10 November 2015

Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma

scientific article

Radiation-induced bone marrow apoptosis, inflammatory bystander-type signaling and tissue cytotoxicity.

scientific article published on 6 November 2012

Radiation-induced delayed bystander-type effects mediated by hemopoietic cells

scientific article published on 01 June 2010

Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation.

scientific article published on October 2003

Rapid technique of DNA-DNA in situ hybridisation on formalin fixed tissue sections using microwave irradiation

scientific article published on August 1987

Recent Advances in Pathology: the 2019 Annual Review Issue of The Journal of Pathology

scientific article published on 01 April 2019

Recent Advances in Pathology: the 2020 Annual Review Issue of The Journal of Pathology

scientific article published on 01 April 2020

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma.

scientific article published on 22 February 2018

Responses to ionizing radiation mediated by inflammatory mechanisms

scientific article published on February 2014

STAT3, stem cells, cancer stem cells and p63.

scientific article published on 22 March 2018

Searching For New Targets And Treatments In The Battle Against Squamous Cell Carcinoma Of The Head And Neck, With Specific Focus On Tumours Of The Tongue.

scientific article published on 16 January 2018

Soft tissue gliomatosis--heterotopic glial tissue in the subcutis: a case report

scientific article published on 01 June 1987

Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins.

scientific article published on 28 November 2012

Sural nerve biopsies in Guillain-Barre syndrome: axonal degeneration and macrophage-associated demyelination and absence of cytomegalovirus genome

scientific article published in May 1992

TAp63 and ΔNp63 (p40) in prostate adenocarcinomas: ΔNp63 associates with a basal-like cancer stem cell population but not with metastasis

scientific article published on 10 October 2020

The Journal of Pathology 2008 Jeremy Jass Prize for Research Excellence in Pathology

scientific article published in December 2009

The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage.

scientific article published on 17 September 2012

The annexin-V assay reflects susceptibility to in vitro membrane damage in chronic lymphocytic leukemia and may overestimate cell death

scientific article published on 01 March 2009

The association between cell proliferation and apoptosis: studies using the cell cycle-associated proteins Ki67 and DNA polymerase alpha

scientific article

The cell type-specific effect of TAp73 isoforms on the cell cycle and apoptosis.

scientific article

The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site

scientific article

The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

scientific article published on 15 January 2015

The genetic basis of tissue responses to ionizing radiation.

scientific article published on September 2007

The in vivo expression of radiation-induced chromosomal instability has an inflammatory mechanism.

scientific article published on 3 November 2011

The influence of p53 functions on radiation-induced inflammatory bystander-type signaling in murine bone marrow.

scientific article published in April 2013

The role of Epstein-Barr virus in the pathogenesis of Hodgkin's disease.

scientific article published on November 1994

The role of p63 in cancer, stem cells and cancer stem cells.

scientific article published on 20 March 2011

The use of a novel ELISA method for detection of antibodies against p63 in sera from patients diagnosed with oral and/or genital and skin lichen planus.

scientific article published on 29 April 2010

Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility?

scientific article published in November 2003

Transcriptional profiling of formalin fixed paraffin embedded tissue: pitfalls and recommendations for identifying biologically relevant changes

scientific article

Tubulin α-6 chain is a stably expressed reference gene in archival samples of normal oral tissue and oral squamous cell carcinoma.

scientific article published on May 2010

Untargeted effects of ionizing radiation: implications for radiation pathology.

scientific article

Viruses and disease: emerging concepts for prevention, diagnosis and treatment.

scientific article published in January 2015

p53 and Mdm2: not all cells are equal.

scientific article published on December 2007

p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

scientific article published on 3 October 2013

p53 and gamma radiation in the normal breast

scientific article published on 01 November 2009

p63 Transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation.

scientific article published on 7 July 2011

p63 contributes to cell invasion and migration in squamous cell carcinoma of the head and neck.

scientific article published on 14 January 2008

p63 isoforms in triple-negative breast cancer: ΔNp63 associates with the basal phenotype whereas TAp63 associates with androgen receptor, lack of BRCA mutation, PTEN and improved survival

scientific article published on 27 February 2018

ΔNp63 activates EGFR signaling to induce loss of adhesion in triple-negative basal-like breast cancer cells.

scientific article published on 27 March 2017

ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer.

scientific article published on 29 January 2016

ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells

scientific article

∆Np63/p40 correlates with the location and phenotype of basal/mesenchymal cancer stem-like cells in human ER+ and HER2+ breast cancers

scientific article published on 06 December 2019

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