List of works - Smita Saxena

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

scientific article

Aberrant association of misfolded SOD1 with Na(+)/K(+)ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS.

scientific article published on 30 November 2015

C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress

scientific article published on April 2016

Central and peripheral defects in motor units of the diaphragm of spinal muscular atrophy mice

scientific article published on 24 November 2015

Cloning of novel human SEC14p-like proteins: ligand binding and functional properties

scientific article (publication date: June 2003)

Differences in the surface binding and endocytosis of neurotrophins by p75NTR.

scientific article published in June 2004

Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking

scientific article

ER strikes again: Proteostasis Dysfunction In ALS.

scientific article published on 11 March 2016

Epidemiology of inherited cerebellar ataxias and challenges in clinical research

scholarly article published July 2018

High contrast staining for serial block face scanning electron microscopy without uranyl acetate

Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology

scientific article published on 01 December 2019

Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology

scientific article published in January 2016

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.

scientific article published on 5 January 2015

Mechanisms of axon degeneration: from development to disease

scientific article published on 02 August 2007

Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ.

scientific article published on 6 July 2016

Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival

scientific article published on 2 October 2013

Neurotrophin Receptors and Retrograde Signaling: A Long-Distance Relationship

P2X1-regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration

scientific article published on 17 March 2016

Proteasomal inhibition alters the trafficking of the neurotrophin receptor TrkA.

scientific article published on 14 July 2009

Proteostasis impairment in ALS.

scientific article published on 28 March 2016

Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration

scientific article published on July 2011

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

scientific article published on 12 February 2006

Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins

scientific article published on January 2014

The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA.

scientific article published in November 2005

Trophic factors in neurodegenerative disorders

scientific article

List of works by Smita Saxena

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

Aberrant association of misfolded SOD1 with Na(+)/K(+)ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS.

C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress

Central and peripheral defects in motor units of the diaphragm of spinal muscular atrophy mice

Cloning of novel human SEC14p-like proteins: ligand binding and functional properties

Differences in the surface binding and endocytosis of neurotrophins by p75NTR.

Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking

ER strikes again: Proteostasis Dysfunction In ALS.

Epidemiology of inherited cerebellar ataxias and challenges in clinical research

High contrast staining for serial block face scanning electron microscopy without uranyl acetate

Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology

Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.

Mechanisms of axon degeneration: from development to disease

Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ.

Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival

Neurotrophin Receptors and Retrograde Signaling: A Long-Distance Relationship

P2X1-regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration

Proteasomal inhibition alters the trafficking of the neurotrophin receptor TrkA.

Proteostasis impairment in ALS.

Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins

The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA.

Trophic factors in neurodegenerative disorders