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List of works by Pedro García

A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae.

scientific article published on March 2015

Aromatic Esters of Bicyclic Amines as Antimicrobials against Streptococcus pneumoniae

scientific article published on 17 September 2015

Auranofin-loaded nanoparticles as a new therapeutic tool to fight streptococcal infections

scientific article published on 18 January 2016

Bactericidal synergism between antibiotics and phage endolysin Cpl-711 to kill multidrug-resistant pneumococcus

scientific article published on 21 September 2018

Bacteriophages of Streptococcus pneumoniae: a molecular approach

scientific article published on January 1997

Biochemical evidence that phaZ gene encodes a specific intracellular medium chain length polyhydroxyalkanoate depolymerase in Pseudomonas putida KT2442: characterization of a paradigmatic enzyme.

scientific article

Chemotherapy with Phage Lysins Reduces Pneumococcal Colonization of the Respiratory Tract.

scientific article

Comparative Analysis of the Physiological and Structural Properties of a Medium Chain Length Polyhydroxyalkanoate Depolymerase from Pseudomonas putida KT2442

Cpl-7, a lysozyme encoded by a pneumococcal bacteriophage with a novel cell wall-binding motif

scientific article

Crystal structure of CbpF, a bifunctional choline-binding protein and autolysis regulator from Streptococcus pneumoniae

scientific article

Crystal structures of CbpF complexed with atropine and ipratropium reveal clues for the design of novel antimicrobials against Streptococcus pneumoniae

scientific article

Crystallization and preliminary X-ray diffraction studies of choline-binding protein F from Streptococcus pneumoniae

scientific article

Crystallization and preliminary X-ray diffraction studies of the complete modular endolysin from Cp-1, a phage infecting Streptococcus pneumoniae

scientific article published on 23 August 2002

Crystallization and preliminary X-ray diffraction studies of the pneumococcal teichoic acid phosphorylcholine esterase Pce.

scientific article published in February 2005

Crystallization and preliminary crystallographic analysis of the catalytic module of endolysin from Cp-7, a phage infecting Streptococcus pneumoniae

scientific article published on 26 May 2010

Csl2, a novel chimeric bacteriophage lysin to fight infections caused by Streptococcus suis, an emerging zoonotic pathogen

scientific article published on 28 November 2017

DNA-release by Streptococcus pneumoniae autolysin LytA induced Krueppel-like factor 4 expression in macrophages

scientific article published on 10 April 2018

Disposable magnetic DNA sensors for the determination at the attomolar level of a specific enterobacteriaceae family gene.

scientific article published on 7 October 2008

Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1

scientific article

Evidence of localized prophage-host recombination in the lytA gene, encoding the major pneumococcal autolysin

scientific article published on 19 March 2010

High-resolution structural insights on the sugar-recognition and fusion tag properties of a versatile β-trefoil lectin domain from the mushroom Laetiporus sulphureus

scientific article

Improving the lethal effect of cpl-7, a pneumococcal phage lysozyme with broad bactericidal activity, by inverting the net charge of its cell wall-binding module

scientific article published on 19 August 2013

In vitro protein-primed initiation of pneumococcal phage Cp-1 DNA replication occurs at the third 3' nucleotide of the linear template: a stepwise sliding-back mechanism

scientific article published in July 1996

Inhibition of lysis by antibody against phage-associated lysin and requirement of choline residues in the cell wall for progeny phage release inStreptococcus pneumoniae

Inhibition of pneumococcal choline-binding proteins and cell growth by esters of bicyclic amines

scientific article published on 01 January 2007

Insights into pneumococcal pathogenesis from the crystal structure of the modular teichoic acid phosphorylcholine esterase Pce.

scientific article published on 15 May 2005

Insights into the structure-function relationships of pneumococcal cell wall lysozymes, LytC and Cpl-1.

scientific article published on 30 July 2008

MM1, a temperate bacteriophage of the type 23F Spanish/USA multiresistant epidemic clone of Streptococcus pneumoniae: structural analysis of the site-specific integration system.

scientific article

Modular organization of the lytic enzymes of Streptococcus pneumoniae and its bacteriophages

scientific article

Monomodular Pseudomonas aeruginosa phage JG004 lysozyme (Pae87) contains a bacterial surface-active antimicrobial peptide-like region and a possible substrate-binding subdomain

scientific article published on 04 March 2022

Multivalent choline dendrimers as potent inhibitors of pneumococcal cell-wall hydrolysis

scientific article

Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae

scientific article

New tool for spreading proteins to the environment: Cry1Ab toxin immobilized to bioplastics

scientific article published on 7 December 2005

Nucleotide sequence and transcription of the left early region of Streptococcus pneumoniae bacteriophage Cp-1 coding for the terminal protein and the DNA polymerase

scientific article published on August 1995

PL3 Amidase, a Tailor-made Lysin Constructed by Domain Shuffling with Potent Killing Activity against Pneumococci and Related Species

scientific article published on 28 July 2016

Pneumococcal phosphorylcholine esterase, Pce, contains a metal binuclear center that is essential for substrate binding and catalysis

scientific article published on 31 October 2005

Role of Pneumococcal Autolysin for KLF4 Expression and Chemokine Secretion in Lung Epithelium

scientific article

Streptococcus pneumoniae-Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol

scientific article published on 15 December 2014

Structural and thermodynamic characterization of Pal, a phage natural chimeric lysin active against pneumococci

scientific article published on 9 July 2004

Structural basis for selective recognition of pneumococcal cell wall by modular endolysin from phage Cp-1

scientific article

Study of phenolic compounds in virgin olive oils of the Picual variety

Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence

scientific article

The puzzle of zmpB and extensive chain formation, autolysis defect and non-translocation of choline-binding proteins in Streptococcus pneumoniae.

scientific article

The recA gene of Streptococcus pneumoniae is part of a competence-induced operon and controls lysogenic induction

scientific article published in January 1995

Thermal stability of Cpl-7 endolysin from the streptococcus pneumoniae bacteriophage Cp-7; cell wall-targeting of its CW_7 motifs

scientific article

Ultrasensitive detection of coliforms by means of direct asymmetric PCR combined with disposable magnetic amperometric genosensors.

scientific article

Unravelling the structure of the pneumococcal autolytic lysozyme

scientific article published on October 2005

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