List of works - Jacek Mokrosinski

A Novel Thyrotropin-Releasing Hormone Receptor Missense Mutation (P81R) in Central Congenital Hypothyroidism.

scientific article published on 6 January 2016

Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach

scientific article published on 30 August 2011

An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor

scientific article published on 05 September 2012

Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network

scientific article published on 12 August 2015

Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

scientific article published on 15 April 2010

Dysregulation of betaglycan expression in primary human endometrial carcinomas.

scientific article

Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

scientific article published on 8 July 2017

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012

Expression of endoglin in primary endometrial cancer

scientific article published on 22 November 2011

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

article

Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism

scientific article published on 19 March 2007

Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

scientific article published on 30 July 2012

Modulation of the constitutive activity of the ghrelin receptor by use of pharmacological tools and mutagenesis

scientific article published on January 1, 2010

Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor

scientific article

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

scientific article published in February 2018

The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling

scientific article

The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

scientific article published on 05 November 2018

The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.

scientific article published on December 2016

List of works by Jacek Mokrosinski

A Novel Thyrotropin-Releasing Hormone Receptor Missense Mutation (P81R) in Central Congenital Hypothyroidism.

Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach

An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor

Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network

Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

Dysregulation of betaglycan expression in primary human endometrial carcinomas.

Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

Expression of endoglin in primary endometrial cancer

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism

Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

Modulation of the constitutive activity of the ghrelin receptor by use of pharmacological tools and mutagenesis

Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling

The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.