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List of works by Fabio Di Domenico

Aberrant insulin signaling in Alzheimer's disease: current knowledge

scientific article

Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways

scientific article

Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype

scientific article published on 08 March 2016

Advanced glycation end products in diabetic patients with optimized glycaemic control and their effects on endothelial reactivity: possible implications in venous graft failure.

scientific article published in July 2009

Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.

scientific article published on 26 February 2015

Antioxidants in cervical cancer: chemopreventive and chemotherapeutic effects of polyphenols.

scientific article published on 12 October 2011

Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain

scientific article published on 18 July 2011

Autoantibodies Profile in Matching CSF and Serum from AD and aMCI patients: Potential Pathogenic Role and Link to Oxidative Damage

scientific article published on 18 December 2015

BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain-Implications for Neurodegeneration

scientific article published on 27 July 2020

Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer's disease

scientific article

Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53

scientific article

Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease

scientific article published on 02 August 2018

Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain

scientific article

Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.

scientific article

Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease

scientific article published on 05 July 2018

Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease

scientific article published on 9 November 2011

CURRENT DEVELOPMENTS IN DRUG ELUTING DEVICES: Introductory Editorial: Drug-Eluting Stents or Drug-Eluting Grafts? Insights from Proteomic Analysis

scientific article published on January 2016

Cathepsin D as a therapeutic target in Alzheimer's disease.

scientific article published on 2 November 2016

Circulating biomarkers of protein oxidation for Alzheimer disease: expectations within limits

scientific article published on 12 October 2011

Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics

scientific article published on 7 September 2012

Doxorubicin-induced thymus senescence

scientific article published on 09 November 2010

Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models.

scientific article published in January 2018

Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach

scientific article

Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain

scientific article

Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity

scientific article published on 08 January 2009

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HO-1/BVR-a system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: a potential biochemical marker for the prediction of the disease

scientific article published in January 2012

Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment

scientific article

Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach

scientific article published on 18 April 2017

Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm

scientific article published on 14 December 2015

Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.

scientific article published on 18 April 2013

Increased Mammalian Target of Rapamycin Signaling Contributes to the Accumulation of Protein Oxidative Damage in a Mouse Model of Down's Syndrome

scientific article published on 26 November 2015

Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro.

scientific article published on 2 May 2012

Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome

scientific article published on 06 November 2018

Involvement of Stat3 in mouse brain development and sexual dimorphism: a proteomics approach.

scientific article

Involvement of oxidative stress in occurrence of relapses in multiple sclerosis: the spectrum of oxidatively modified serum proteins detected by proteomics and redox proteomics analysis

scientific article

It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease

scientific article

Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B.

scientific article published on 21 February 2012

Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: A novel mechanism of action ⬇️

scientific article published on December 27, 2010

Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease

scientific article published on 06 February 2019

Mass spectrometry and redox proteomics: applications in disease

scientific article

Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.

scientific article

Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment.

scientific article published in January 2011

Oxidative damage in rat brain during aging: interplay between energy and metabolic key target proteins

scientific article published on 21 October 2010

Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients.

scientific article published on 8 December 2015

Oxidative stress in HPV-driven viral carcinogenesis: redox proteomics analysis of HPV-16 dysplastic and neoplastic tissues

scientific article

Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid

scientific article published on 24 February 2011

Pharmacologic Approaches Against Advanced Glycation End Products (AGEs) in Diabetic Cardiovascular Disease

scientific article

Poly-ubiquitin profile in Alzheimer disease brain

scientific article published on 09 July 2018

Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology.

scientific article

Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes.

scientific article published on 9 March 2009

Protein nitration profile of CD3 lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection

scientific article published on 12 October 2018

Proteomic analysis for the study of amniotic fluid protein composition

scientific article published on July 2009

Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease

scientific article published on 18 July 2018

Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age

scientific article published on 25 June 2011

Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children

scientific article published on 11 November 2020

Proteomics analysis of protein expression and specific protein oxidation in human papillomavirus transformed keratinocytes upon UVB irradiation

scientific article

Proteomics strategies to analyze HPV-transformed cells: relevance to cervical cancer.

scientific article published on October 2013

Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects ⬇️

scientific article published on April 13, 2011

Redox proteomic analysis of serum from aortic anerurysm patients: insights on oxidation of specific protein target.

scientific article

Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease

scientific article published on 20 March 2012

Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease.

scientific article

Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis

scientific article

Redox proteomics in aging rat brain: involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process

scientific article published on 8 October 2010

Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity

scientific article published on 28 February 2019

Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome

scientific article published on 09 March 2019

Serum proteomics in patients with diagnosis of abdominal aortic aneurysm

scientific article published on 21 November 2011

Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion

scientific article

Shining a light on defective autophagy by proteomics approaches: implications for neurodegenerative illnesses

scientific article published on 14 November 2019

Simvastatin attenuates the endothelial pro-thrombotic shift in saphenous vein grafts induced by Advanced glycation endproducts

scientific article published on 21 December 2013

Statins more than cholesterol lowering agents in Alzheimer disease: their pleiotropic functions as potential therapeutic targets.

scientific article

Strategy to reduce free radical species in Alzheimer's disease: an update of selected antioxidants.

scientific article published on 22 September 2014

Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives

scientific article published on 01 October 2019

Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies

scientific article published on 2 October 2016

The Anti-Diabetic Drug Metformin Rescues Aberrant Mitochondrial Activity and Restrains Oxidative Stress in a Female Mouse Model of Rett Syndrome

scientific article published on 01 June 2020

The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome

scientific article published on 30 November 2020

The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliation

scientific article

The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics

scientific article published on 14 September 2016

The wheat germ agglutinin-fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: Implications for disease pathogenesis and progression

scientific article published on 8 October 2010

Therapeutic potential of rescuing protein O-GlcNAcylation in tau-related pathologies

scientific article published on 30 October 2018

Unraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: insights from proteomics.

scientific article published on February 2014

Usefulness of preprocedural levels of advanced glycation end products to predict restenosis in patients with controlled diabetes mellitus undergoing drug-eluting stent implantation for stable angina pectoris (from the Prospective ARMYDA-AGEs Study).

scientific article published on 2 April 2013

mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia

scientific article published on 11 August 2017

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