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List of works by Kyung-Min Lim

18β-glycyrrhetinic acid attenuates anandamide-induced adiposity and high-fat diet induced obesity

scientific article published on 31 March 2014

2,2-Dimethyl-4,5-diaryl-3(2 H )furanone derivatives as selective cyclo-oxygenase-2 inhibitors

scientific article published on 01 January 2001

2,3-diarylpyran-4-ones: a new series of selective cyclooxygenase-2 inhibitors.

scientific article published in May 2004

A Src-family-tyrosine kinase, Lyn, is required for efficient IFN-β expression in pattern recognition receptor, RIG-I, signal pathway by interacting with IPS-1.

scientific article published on 10 January 2015

A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis

scientific article published on 17 February 2010

A new 3D reconstituted human corneal epithelium model as an alternative method for the eye irritation test

scientific article published on 30 October 2010

A novel adamantyl benzylbenzamide derivative, AP736, suppresses melanogenesis through the inhibition of cAMP-PKA-CREB-activated microphthalmia-associated transcription factor and tyrosinase expression

scientific article published on November 2013

A novel organogermanium protected atopic dermatitis induced by oxazolone

scientific article published on 27 May 2010

A rapid and highly sensitive UPLC-MS/MS method using pre-column derivatization with 2-picolylamine for intravenous and percutaneous pharmacokinetics of valproic acid in rats

scientific article published on 26 August 2013

Act on the Registration and Evaluation of Chemicals (K-REACH) and replacement, reduction or refinement best practices

scientific article published on 19 December 2016

Alternatives to In Vivo Draize Rabbit Eye and Skin Irritation Tests with a Focus on 3D Reconstructed Human Cornea-Like Epithelium and Epidermis Models ⬇️

scientific article published on 15 July 2017

Analysis of Statistical Methods Currently used in Toxicology Journals.

scientific article

Anti-Pigmentary Effect of (-)-4-Hydroxysattabacin from the Marine-Derived Bacterium Bacillus sp

scientific article

Anti-inflammatory and analgesic activities of SKLJI, a highly purified and injectable herbal extract of Lonicera japonica

scientific article published on 7 October 2010

Anti-inflammatory and barrier protecting effect of Lithospermum erythrorhizon extracts in chronic oxazolone-induced murine atopic dermatitis

scientific article published on 3 August 2009

Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice.

scientific article published on 11 June 2018

Antipruritic Effects of TRPV1 Antagonist in Murine Atopic Dermatitis and Itching Models

article

Appraisal of within- and between-laboratory reproducibility of non-radioisotopic local lymph node assay using flow cytometry, LLNA:BrdU-FCM: comparison of OECD TG429 performance standard and statistical evaluation

scientific article published on 27 February 2015

Arsenic levels in the groundwater of Korea and the urinary excretion among contaminated area.

scientific article published on 6 April 2016

Arsenite-enhanced procoagulant activity through phosphatidylserine exposure in platelets

scientific article published on 5 October 2007

B cell increases and ex vivo IL-2 production as secondary endpoints for the detection of sensitizers in non-radioisotopic local lymph node assay using flow cytometry

scientific article published on 2 January 2012

Black soybean extract can attenuate thrombosis through inhibition of collagen-induced platelet activation

scientific article

Carnosic acid, a phenolic diterpene from rosemary, prevents UV-induced expression of matrix metalloproteinases in human skin fibroblasts and keratinocytes

scientific article published on May 2013

Cathepsin G inhibitor prevents ultraviolet B-induced photoaging in hairless mice via inhibition of fibronectin fragmentation

scientific article

Co-oxidation-mediated xenobiotic activation and cytotoxicity by 12-lipoxygenase in intact platelets

scientific article published on 4 March 2008

Comparison of BALB/c and CBA/J mice for the local lymph node assay using bromodeoxyuridine with flow cytometry (LLNA: BrdU-FCM).

scientific article published on 2 November 2016

Comparison of flow cytometry and immunohistochemistry in non-radioisotopic murine lymph node assay using bromodeoxyuridine

scientific article published on 30 October 2009

Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric).

scientific article published on 9 January 2017

Decrease of Ceramides with Very Long–Chain Fatty Acids and Downregulation of Elongases in a Murine Atopic Dermatitis Model

article

Determination of N-nitrosodiethanolamine, NDELA in cosmetic ingredients and products by mixed mode solid phase extraction and UPLC–tandem mass spectrometry with porous graphitic carbon column through systemic sample pre-cleanup procedure

Determination of spatial distribution of melamine-cyanuric acid crystals in rat kidney tissue by histology and imaging matrix-assisted laser desorption/ionization quadrupole time-of-flight mass spectrometry

scientific article

Determination of the key innate genes related to individual variation in carbon tetrachloride-induced hepatotoxicity using a pre-biopsy procedure.

scientific article published on 27 May 2009

Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases.

scientific article

Discrimination of <i>Lycium chinense</i> and <i>L. barbarum</i> Based on Metabolite Analysis and Hepatoprotective Activity

scientific article published on 10 December 2020

Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes

scientific article published on 22 December 2015

Doxorubicin-induced platelet cytotoxicity: a new contributory factor for doxorubicin-mediated thrombocytopenia.

scientific article

Doxorubicin-induced platelet procoagulant activities: an important clue for chemotherapy-associated thrombosis

scientific article published on 24 August 2011

Dysfunction of vascular smooth muscle and vascular remodeling by simvastatin

scientific article published on 21 January 2014

Effect of Lead(IV) Acetate on Procoagulant Activity in Human Red Blood Cells

scientific article published on 30 December 2009

Effects of Electromagnetic Waves with LTE and 5G Bandwidth on the Skin Pigmentation In Vitro

scientific article published on 26 December 2020

Effects of chitooligosaccharide lactate salt on activity of acetaldehyde dehydrogenase

scientific article published on October 2010

Effects of chitooligosaccharide lactate salt on sleep deprivation-induced fatigue in mice

scientific article published on January 2010

Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta

scientific article

Erythrophagocytosis of lead-exposed erythrocytes by renal tubular cells: possible role in lead-induced nephrotoxicity

scientific article

Evaluation of Eye Irritation Potential of Solid Substance with New 3D Reconstructed Human Cornea Model, MCTT HCE(TM).

scientific article published on July 2015

Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo.

scientific article published on 21 March 2011

Evaluation of ocular irritancy of coal-tar dyes used in cosmetics employing reconstructed human cornea-like epithelium and short time exposure tests

scientific article

Evaluation of radioisotopic and non-radioisotopic versions of local lymph node assays for subcategorization of skin sensitizers compliant to UN GHS rev 4.

scientific article published on 10 February 2017

Exploration and comparison of in vitro eye irritation tests with the ISO standard in vivo rabbit test for the evaluation of the ocular irritancy of contact lenses.

scientific article published on 2 September 2016

Expression Levels of GABA-A Receptor Subunit Alpha 3, Gabra3 and Lipoprotein Lipase, Lpl Are Associated with the Susceptibility to Acetaminophen-Induced Hepatotoxicity

scientific article published on 19 August 2016

Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity

scientific article published on 2 October 2009

Ginkgo biloba extract enhances antiplatelet and antithrombotic effects of cilostazol without prolongation of bleeding time

scientific article

High-Dose Vitamin C Injection to Cancer Patients May Promote Thrombosis Through Procoagulant Activation of Erythrocytes

scientific article published on 2 July 2015

Highly expressed protein kinase A inhibitor α and suppression of protein kinase A may potentiate acetaminophen-induced hepatotoxicity

scientific article published on 6 June 2014

Hydrogen peroxide and monoethanolamine are the key causative ingredients for hair dye-induced dermatitis and hair loss

scientific article published on 4 January 2012

Identification of cornifelin and early growth response-1 gene as novel biomarkers for in vitro eye irritation using a 3D reconstructed human cornea model MCTT HCE™.

scientific article published on 7 November 2014

Immunohistological comparison of cutaneous pathology of three representative murine atopic dermatitis models

scientific article published on 23 May 2010

Impact of High Fat Diet-induced Obesity on the Plasma Levels of Monoamine Neurotransmitters in C57BL/6 Mice.

scientific article

In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives.

scientific article published on February 2004

Increased cis-to-trans urocanic acid ratio in the skin of chronic spontaneous urticaria patients

scientific article

Inhibition of platelet aggregation by 1-methyl-4-phenyl pyridinium ion (MPP+) through ATP depletion: Evidence for the reduced platelet activities in Parkinson's disease

scientific article published on May 2009

Inhibitory effects of black soybean on platelet activation mediated through its active component of adenosine

scholarly article by Keunyoung Kim et al published March 2013 in Thrombosis Research

Inorganic arsenite potentiates vasoconstriction through calcium sensitization in vascular smooth muscle

scientific article

Investigation of dermal toxicity of ionic liquids in monolayer-cultured skin cells and 3D reconstructed human skin models

scientific article

KeraSkin-VM: a novel reconstructed human epidermis model for skin irritation tests.

scientific article published on 10 March 2014

Lead-induced procoagulant activation of erythrocytes through phosphatidylserine exposure may lead to thrombotic diseases

scientific article

Liquid Chromatography Mass Spectrometry-Based Metabolite Pathway Analyses of Myeloma and Non-Hodgkin's Lymphoma Patients

scientific article

Liver X receptor activation inhibits melanogenesis through the acceleration of ERK-mediated MITF degradation

scientific article published on 6 December 2012

Low level of lead can induce phosphatidylserine exposure and erythrophagocytosis: a new mechanism underlying lead-associated anemia

scientific article published on 11 April 2011

Low-Dose Bisphenol A Increases Bile Duct Proliferation in Juvenile Rats: A Possible Evidence for Risk of Liver Cancer in the Exposed Population?

scientific article published on 21 August 2017

Low-level mercury can enhance procoagulant activity of erythrocytes: a new contributing factor for mercury-related thrombotic disease

scientific article

Lysophosphatidic Acid Induces Thrombogenic Activity Through Phosphatidylserine Exposure and Procoagulant Microvesicle Generation in Human Erythrocytes

article by Seung-Min Chung et al published February 2007 in Arteriosclerosis, Thrombosis, and Vascular Biology

Metabolomic analysis of amino acids and lipids in human hair altered by dyeing, perming and bleaching

Methylated Organic Metabolites of Arsenic and their Cardiovascular Toxicities

article

Modeling lifetime costs and health outcomes attributable to secondhand smoke exposure at home among Korean adult women.

scientific article published on 17 May 2017

Nervonoylceramide (C24:1Cer), a lipid biomarker for ocular irritants released from the 3D reconstructed human cornea-like epithelium, MCTT HCE™.

scientific article

New Anticoagulants for the Prevention and Treatment of Venous Thromboembolism

scientific article published on 6 April 2017

Novel Antiplatelet Activity of Protocatechuic Acid through the Inhibition of High Shear Stress-Induced Platelet Aggregation

scientific article published on 13 September 2012

Novel anti-melanogenic hexapeptoids, PAL-10 and PAL-12.

scientific article published on 10 March 2015

Novel inhibitory effects of cardamonin on thromboxane A2-induced scratching response: Blocking of Gh/transglutaminase-2 binding to thromboxane A2 receptor.

scientific article

Oral and topical pharmacokinetic studies of a novel TRPV1 antagonist, PAC-14028 in rats and minipigs using liquid chromatography/tandem mass spectrometric method.

scientific article

PAL-12, a new anti-aging hexa-peptoid, inhibits UVB-induced photoaging in human dermal fibroblasts and 3D reconstructed human full skin model, Keraskin-FT™.

scientific article

Pancreatic cancer induced by in vivo electroporation-enhanced sleeping beauty transposon gene delivery system in mouse.

scientific article

Performance standard-based validation study for local lymph node assay: 5-bromo-2-deoxyuridine-flow cytometry method.

scientific article published on 15 June 2016

Pharmacokinetic evaluation of an oral tablet form of low-molecular-weight heparin and deoxycholic acid conjugate as a novel oral anticoagulant

article by Jin Woo Park et al published 2011 in Thrombosis and Haemostasis

Pharmacokinetic study of ginsenoside Re with pure ginsenoside Re and ginseng berry extracts in mouse using ultra performance liquid chromatography/mass spectrometric method

scientific article published on 18 August 2009

Platelet Shape Changes and Cytoskeleton Dynamics as Novel Therapeutic Targets for Anti-Thrombotic Drugs

scientific article

Potent anti-inflammatory effects of two quinolinedione compounds, OQ1 and OQ21, mediated by dual inhibition of inducible NO synthase and cyclooxygenase-2

scientific article published on 19 January 2009

Potentiation of vasoconstriction and pressor response by low concentration of monomethylarsonous acid (MMA(III)).

scientific article published on 25 June 2011

Predictive capacity of a non-radioisotopic local lymph node assay using flow cytometry, LLNA:BrdU-FCM: Comparison of a cutoff approach and inferential statistics

scientific article

Predose blood gene expression profiles might identify the individuals susceptible to carbon tetrachloride-induced hepatotoxicity

scientific article published on 3 February 2010

Prevalidation trial for a novel in vitro eye irritation test using the reconstructed human cornea-like epithelial model, MCTT HCE™.

scientific article published on 19 November 2016

Procoagulant and prothrombotic activation of human erythrocytes by phosphatidic acid

scientific article published on 21 May 2010

Protective Role of Mitochondrial Peroxiredoxin III against UVB-Induced Apoptosis of Epidermal Keratinocytes.

scientific article

Rapid, simultaneous and nanomolar determination of pyroglutamic acid and cis-/trans-urocanic acid in human stratum corneum by hydrophilic interaction liquid chromatography (HILIC)–electrospray ionization tandem mass spectrometry

scientific article published on 12 April 2012

Relationship between cutaneous barrier function and ceramide species in human stratum corneum.

scientific article

Relationship of ceramide–, and free fatty acid–cholesterol ratios in the stratum corneum with skin barrier function of normal, atopic dermatitis lesional and non-lesional skins

scientific article published on 14 October 2014

Rhododenol and raspberry ketone impair the normal proliferation of melanocytes through reactive oxygen species-dependent activation of GADD45.

scientific article published on 8 February 2016

S100A7 (psoriasin) inhibits human epidermal differentiation by enhanced IL-6 secretion through IκB/NF-κB signalling.

scientific article published on 6 April 2016

Saccharomonopyrones A-C, New α-Pyrones from a Marine Sediment-Derived Bacterium Saccharomonospora sp. CNQ-490. ⬇️

scientific article

Salsolinol, an endogenous neurotoxin, enhances platelet aggregation and thrombus formation

Shear stress-induced pH increase in plasma is mediated by a decrease in PCO2: The increase in pH enhances shear stress-induced P-selectin expression in platelets

Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity

article by Eun-Ah Jun et al published 7 September 2010 in Nanotoxicology

Simvastatin induces the apoptosis of normal vascular smooth muscle through the disruption of actin integrity via the impairment of RhoA/Rac-1 activity.

scientific article published on 16 June 2016

Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion

scientific article published on 17 December 2013

Submicromolar bisphenol A induces proliferation and DNA damage in human hepatocyte cell lines in vitro and in juvenile rats in vivo

scientific article

Sulforaphane suppresses oligomerization of TLR4 in a thiol-dependent manner

scientific article

Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2.

scientific article published on April 2013

Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester

scientific article published on 12 December 2014

Synthesis of N,N',N"-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor

scientific article published in February 2003

TRPV1 antagonist can suppress the atopic dermatitis-like symptoms by accelerating skin barrier recovery.

scientific article published on 3 November 2010

The effect of epidermal growth factor (EGF) conjugated with low-molecular-weight protamine (LMWP) on wound healing of the skin

scientific article

Titanium dioxide inclusion in backing reduce the photoallergenicity of ketoprofen transdermal patch

scholarly article by Yang-Gyu Choi et al published March 2011 in Archives of Toxicology

Topical Application of Dieckol Ameliorates Atopic Dermatitis in NC/Nga Mice by Suppressing Thymic Stromal Lymphopoietin Production

scientific article published on 5 February 2016

Trivalent methylated arsenical-induced phosphatidylserine exposure and apoptosis in platelets may lead to increased thrombus formation

scientific article published on 6 January 2009

U-shaped Dose Response in Vasomotor Tone: A Mixed Result of Heterogenic Response of Multiple Cells to Xenobiotics

article

Vascular smooth muscle dysfunction and remodeling induced by ginsenoside Rg3, a bioactive component of ginseng

scientific article published on 19 July 2010

Vascular smooth muscle dysfunction induced by monomethylarsonous acid (MMA III): a contributing factor to arsenic-associated cardiovascular diseases

scientific article published on 12 August 2008

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