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List of works by Annalisa Lonetti

A polymorphism in the chromosome 9p21 ANRIL locus is associated to Philadelphia positive acute lymphoblastic leukemia

scientific article

AICDA expression in BCR/ABL1-positive acute lymphoblastic leukaemia is associated with a peculiar gene expression profile.

scientific article published on 31 January 2011

Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia.

scientific article published on 6 November 2013

Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting

scientific article published on September 2015

Application of the whole-transcriptome shotgun sequencing approach to the study of Philadelphia-positive acute lymphoblastic leukemia.

scientific article published on 9 March 2012

Autophagy in acute leukemias: a double-edged sword with important therapeutic implications

scientific article

B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?

scientific article published on 24 November 2020

CDKN2A/B alterations impair prognosis in adult BCR-ABL1-positive acute lymphoblastic leukemia patients.

scientific article

Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments

scientific article published on June 2012

Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

scientific article published on 20 November 2013

Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients.

scientific article published on 17 September 2009

Enhancing the effectiveness of nucleoside analogs with mTORC1 blockers to treat acute myeloid leukemia patients

scientific article published on 24 May 2013

Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

scientific article

Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene

scientific article published on 21 January 2017

IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis

scientific article published on 21 October 2010

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia

scientific article

Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute

scientific article

Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases

scientific article

Identification of different Ikaros cDNA transcripts in Philadelphia-positive adult acute lymphoblastic leukemia by a high-throughput capillary electrophoresis sizing method

article published in 2008

Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway

scientific article published on 24 October 2016

In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia

scientific article

Inhibition of Methyltransferase DOT1L Sensitizes to Sorafenib Treatment AML Cells Irrespective of MLL-Rearrangements: A Novel Therapeutic Strategy for Pediatric AML

scientific article published on 20 July 2020

Insights on the Interplay between Cells Metabolism and Signaling: A Therapeutic Perspective in Pediatric Acute Leukemias

scientific article published on 28 August 2020

New advances in targeting aberrant signaling pathways in T-cell acute lymphoblastic leukemia

scientific article published on 05 September 2019

Philadelphia-positive acute lymphoblastic leukemia patients already harbor BCR-ABL kinase domain mutations at low levels at the time of diagnosis

scientific article

Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin.

scientific article published on 15 May 2012

Single Nucleotide Polymorphisms as Genomic Markers for High-Throughput Pharmacogenomic Studies

scientific article published in January 2016

Successes and Challenges for Diagnosis and Therapy of Acute Leukemia

scientific article published on 22 November 2019

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB.

scientific article published on 22 November 2015

Targeting phosphatidylinositol 3-kinase signaling in acute myelogenous leukemia

scientific article published on 11 June 2013

Targeting signaling pathways in T-cell acute lymphoblastic leukemia initiating cells

scientific article published on 30 April 2014

Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients

scientific article published on 12 February 2016

The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party

scientific article

Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (review).

scientific article published on 26 June 2014

Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.

scientific article

Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia

scientific article

Use of a high sensitive nanofluidic array for the detection of rare copies of BCR-ABL1 transcript in patients with Philadelphia-positive acute lymphoblastic leukemia in complete response

scientific article published on 18 February 2014

c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells

scientific article

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