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List of works by Guenter Haemmerle

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

scientific article published on 21 November 2008

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

scientific article

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

scientific article published on 21 August 2011

Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice

scientific article published on 29 May 2012

Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice

scientific article published on 17 November 2016

Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

scientific article published in May 2012

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

scientific article published in Science

Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice.

scientific article published on 2 June 2009

Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues

scientific article

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

scientific article published on 16 January 2014

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

scientific journal article

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

scientific article published on 23 October 2008

Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling

scientific article published on 31 August 2009

Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion

scientific article published on 22 April 2009

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

scientific article published on 27 February 2015

Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids

scientific article

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

scientific article

Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist

scientific article published on January 2012

Cardiac oxidative stress in a mouse model of neutral lipid storage disease

scientific article published on 15 July 2013

Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression

scientific article published on 17 March 2004

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

scientific article published on 23 January 2013

Cardioprotection and lifespan extension by the natural polyamine spermidine.

scientific article

Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice

scientific article

Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363

scientific article

Comparative gene identification-58/α/β hydrolase domain 5: more than just an adipose triglyceride lipase activator?

scientific article

Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue

scientific article published on 16 August 2003

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

scientific article

Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis

scientific article published in November 2003

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation

scientific article published on 25 May 2013

Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase

scientific article

Endothelial dysfunction in adipose triglyceride lipase deficiency

scientific article published on 21 March 2014

Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue

scientific article published on January 2005

Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver

scientific article published on 31 August 2009

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

scientific article published in March 2012

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

scientific article published on 27 February 2015

Fat in the heart: The enzymatic machinery regulating cardiac triacylglycerol metabolism

scientific article published on 23 February 2016

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.

scientific article published on April 2011

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

scientific article

Fate of fat: the role of adipose triglyceride lipase in lipolysis

scientific article published on 29 October 2008

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling

scientific article published on 7 May 2015

Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis

scientific article

Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.

scientific article published on 14 February 2013

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

scientific article

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

scientific journal article

Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle

scientific article published on 23 January 2002

Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity

scientific article

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.

scientific article published on October 2011

Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice

scientific article

Letting lipids go: hormone-sensitive lipase

scientific article

Lipolysis: pathway under construction

scientific article

Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia

scientific article published on 17 May 2016

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

scientific article published on 27 June 2016

Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice

scientific article

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

scientific article

Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction

scientific article published on 12 December 2011

Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy

scientific article published on 24 January 2013

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

scientific article published on 14 October 2016

Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation

scientific article published on 05 July 2016

Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

scientific article

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

scientific article

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

scientific article published in Journal of Biological Chemistry

The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes

scientific article published on 05 June 2013

The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis

scientific article

The lipolytic proteome of mouse adipose tissue

scientific article published on 26 July 2005

Validated Comprehensive Analytical Method for Quantification of Coenzyme A Activated Compounds in Biological Tissues by Online Solid-Phase Extraction LC/MS/MS

scientific article published on 09 July 2008

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

scientific article

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