List of works - Neil G. Berry

4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance

scientific article published in December 2014

A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.

scientific article

Abacavir Forms Novel Cross-Linking Abacavir Protein Adducts in Patients

article

Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex

scientific article

Activation of T cells by carbamazepine and carbamazepine metabolites

scientific article

An adaptable peptide-based porous material

scientific article published on August 2010

Anion recognition as a method for templating pseudorotaxane formation

scientific article

Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1

scientific article

Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action

scientific article published on 20 June 2011

Antitubercular pharmacodynamics of phenothiazines

scientific article published on 9 December 2012

Artemisinin-polypyrrole conjugates: synthesis, DNA binding studies and preliminary antiproliferative evaluation

scientific article

Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century

scientific article published on March 2009

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

scientific article published on 29 July 2015

Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins

scientific article

Characterization of the T-cell response in a patient with phenindione hypersensitivity

scientific article (publication date: June 2005)

Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure–property relationship

article

Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites.

scientific article published on 23 February 2016

Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.

scientific article published on 20 May 2008

Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin

scientific article published on 03 November 2006

Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients

scientific article

Electron-Deficient Phosphines Accelerate the Heck Reaction of Electronrich Olefins in Ionic Liquid

Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity

scientific article published on 27 October 2010

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

scientific article

Guest-adaptable and water-stable peptide-based porous materials by imidazolate side chain control

scientific article published on 2 December 2013

HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.

scientific article

Heteroditopic Transition Metal Dithiocarbamate Receptors for Binding Cation-Anion Ion Pairs

High sulfur content polymers: The effect of crosslinker structure on inverse vulcanization

scientific article published on 24 August 2018

Hydrogen-bonding-promoted oxidative addition and regioselective arylation of olefins with aryl chlorides

scientific article published on 28 October 2010

Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library

scientific article published on 27 September 2017

Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo

scientific article published on February 2006

Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.

scientific article

Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

scientific article published on 24 February 2012

Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

scientific article

In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group

scientific article

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

scientific article published in Nature Communications

Mechanistic Insight into the Superoxide Induced Ring Opening in Propylene Carbonate Based Electrolytes using in Situ Surface-Enhanced Infrared Spectroscopy

scientific article published on 11 March 2016

Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD

scientific article

NMR studies of the conformational effect of single and double 3'-S-phosphorothiolate substitutions within deoxythymidine trinucleotides

scientific article published on April 2007

New tools for carbohydrate sulfation analysis: heparan sulfate 2--sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

article

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

article

One class classification as a practical approach for accelerating π-π co-crystal discovery

scientific article published on 08 December 2020

Pd−mBDPP-Catalyzed Regioselective Internal Arylation of Electron-Rich Olefins by Aryl Halides

Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target

scientific article

Potent Antimalarial 2-Pyrazolyl Quinolone bc 1 (Qi) Inhibitors with Improved Drug-like Properties

scientific article published on 19 October 2018

Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections

scientific article published on 16 December 2019

Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis

scholarly article

Second generation analogues of RKA182: synthetic tetraoxanes with outstanding in vitro and in vivo antimalarial activities

article

Side-chain control of porosity closure in single- and multiple-peptide-based porous materials by cooperative folding

scientific article published on 23 February 2014

Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis

scientific article

Stimulation of human T cells with sulfonamides and sulfonamide metabolites.

scientific article published in February 2010

Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains

scholarly article by Alexandre S Lawrenson et al published 17 August 2018 in Journal of Molecular Modeling

Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology

scientific article published on 15 September 2006

Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.

scientific article published on April 2009

Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides.

scientific article

Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.

scientific article published on 14 November 2017

The synthesis and structure of chiral enamine N-oxides

scientific article published on 01 July 2014

Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication

scientific article published on 23 May 2011

Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication

scientific article

Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation

scientific article published on 13 September 2015

Will it gel? Successful computational prediction of peptide gelators using physicochemical properties and molecular fingerprints

X-ray Crystallography and Computational Docking for the Detection and Development of Protein–Ligand Interactions ⬇️

scientific article published on January 1, 2013

List of works by Neil G. Berry

4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance

A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.

Abacavir Forms Novel Cross-Linking Abacavir Protein Adducts in Patients

Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex

Activation of T cells by carbamazepine and carbamazepine metabolites

An adaptable peptide-based porous material

Anion recognition as a method for templating pseudorotaxane formation

Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1

Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action

Antitubercular pharmacodynamics of phenothiazines

Artemisinin-polypyrrole conjugates: synthesis, DNA binding studies and preliminary antiproliferative evaluation

Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins

Characterization of the T-cell response in a patient with phenindione hypersensitivity

Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure–property relationship

Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites.

Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.

Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin

Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients

Electron-Deficient Phosphines Accelerate the Heck Reaction of Electronrich Olefins in Ionic Liquid

Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

Guest-adaptable and water-stable peptide-based porous materials by imidazolate side chain control

HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.

Heteroditopic Transition Metal Dithiocarbamate Receptors for Binding Cation-Anion Ion Pairs

High sulfur content polymers: The effect of crosslinker structure on inverse vulcanization

Hydrogen-bonding-promoted oxidative addition and regioselective arylation of olefins with aryl chlorides

Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library

Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo

Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.

Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Mechanistic Insight into the Superoxide Induced Ring Opening in Propylene Carbonate Based Electrolytes using in Situ Surface-Enhanced Infrared Spectroscopy

Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD

NMR studies of the conformational effect of single and double 3'-S-phosphorothiolate substitutions within deoxythymidine trinucleotides

New tools for carbohydrate sulfation analysis: heparan sulfate 2--sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

One class classification as a practical approach for accelerating π-π co-crystal discovery

Pd−mBDPP-Catalyzed Regioselective Internal Arylation of Electron-Rich Olefins by Aryl Halides

Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target

Potent Antimalarial 2-Pyrazolyl Quinolone bc 1 (Qi) Inhibitors with Improved Drug-like Properties

Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections

Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis

Second generation analogues of RKA182: synthetic tetraoxanes with outstanding in vitro and in vivo antimalarial activities

Side-chain control of porosity closure in single- and multiple-peptide-based porous materials by cooperative folding

Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis

Stimulation of human T cells with sulfonamides and sulfonamide metabolites.

Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains

Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology

Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.

Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides.

Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.

The synthesis and structure of chiral enamine N-oxides

Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication

Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication

Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation

Will it gel? Successful computational prediction of peptide gelators using physicochemical properties and molecular fingerprints

X-ray Crystallography and Computational Docking for the Detection and Development of Protein–Ligand Interactions ⬇️