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List of works by Anthony Fyles

5-hydroxytryptamine-3 receptor antagonist with or without short-course dexamethasone in the prophylaxis of radiation induced emesis: a placebo-controlled randomized trial of the National Cancer Institute of Canada Clinical Trials Group (SC19).

scientific article published in July 2006

A final report of a phase I study of veliparib (ABT-888) in combination with low-dose fractionated whole abdominal radiation therapy (LDFWAR) in patients with advanced solid malignancies and peritoneal carcinomatosis with a dose escalation in ovaria

scientific article

A hypofractionated radiotherapy regimen (0-7-21) for advanced gynaecological cancer patients

scientific article

A multi-institutional analysis of intraoperative radiotherapy for early breast cancer: Does age matter?

scientific article published on 23 June 2017

A phase III randomized study of misonidazole plus radiation vs. radiation alone for cervix cancer

scientific article published in March 2004

A prospective phase I–II trial of the cyclooxygenase-2 inhibitor celecoxib in patients with carcinoma of the cervix with biomarker assessment of the tumor microenvironment

scientific article published on 23 October 2006

A prospective study of DWI, DCE-MRI and FDG PET imaging for target delineation in brachytherapy for cervical cancer

scientific article published on 12 August 2016

A randomized study of two doses of abdominopelvic radiation therapy for patients with optimally debulked stage I, II, and III ovarian cancer

scientific article published on 01 June 1998

A randomized trial of standard versus partially hyperfractionated radiation with or without concurrent 5-fluorouracil in locally advanced cervical cancer

scientific article published on May 1998

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial

scientific article published on 12 February 2018

Adjuvant radiotherapy in women with stage I endometrial cancer: a systematic review

scientific article published on 2 May 2006

Analysis of complications in patients treated with abdomino-pelvic radiation therapy for ovarian carcinoma

scientific article published on January 1, 1992

Anatomic features of interest in women at risk of cardiac exposure from whole breast radiotherapy

scientific article published on 18 May 2015

Anemia, hypoxia and transfusion in patients with cervix cancer: a review.

scientific article

Assessment of the tumor microenvironment in cervix cancer using dynamic contrast enhanced CT, interstitial fluid pressure and oxygen measurements

article

Association between CYP3A4 genotype and risk of endometrial cancer following tamoxifen use

scientific article published on 13 April 2007

Association between Metformin Use and Mortality after Cervical Cancer in Older Women with Diabetes.

scientific article published on 31 December 2015

Association of Apparent Diffusion Coefficient with Disease Recurrence in Patients with Locally Advanced Cervical Cancer Treated with Radical Chemotherapy and Radiation Therapy

scientific article published on 27 October 2015

Automated Weekly Replanning for Intensity-Modulated Radiotherapy of Cervix Cancer

scientific article published on 01 October 2010

Automation and intensity modulated radiation therapy for individualized high-quality tangent breast treatment plans.

scientific article

Borderline epithelial ovarian tumors: a review of 81 cases with an assessment of the impact of treatment

scientific article published on January 1, 1992

Building a New Model of Care for Rapid Breast Radiotherapy Treatment Planning: Evaluation of the Advanced Practice Radiation Therapist in Cavity Delineation

scientific article

Can trained volunteers provide psychosocial support to patients undergoing radiotherapy? The perspective of patients and volunteers

article

Carcinoma of the vagina--experience at the Princess Margaret Hospital (1974-1989).

scientific article

Cervical cancer regression measured using weekly magnetic resonance imaging during fractionated radiotherapy: radiobiologic modeling and correlation with tumor hypoxia

scientific article published on 4 September 2007

Cervix cancer oxygenation measured following external radiation therapy

scientific article published on 01 November 1998

Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx)

scientific article published on 29 August 2012

Chromosomal instability as a prognostic marker in cervical cancer

scientific article published on 6 May 2015

Clinical consequences of upfront pathology review in the randomised PORTEC-3 trial for high-risk endometrial cancer.

scientific article published on 27 November 2017

Comparison of dosimetric parameters derived from whole organ and wall contours for bladder and rectum in cervical cancer patients treated with intracavitary and interstitial brachytherapy.

scientific article published on 6 February 2018

Concomitant intensity modulated boost during whole breast hypofractionated radiotherapy – A feasibility and toxicity study

article

Concurrent cisplatin-based chemotherapy plus radiotherapy for cervical cancer--a meta-analysis

scientific article

Concurrent radiation and chemotherapy in vulvar carcinoma

scientific article published on 01 September 1989

Consensus Recommendations for Radiation Therapy Contouring and Treatment of Vulvar Carcinoma

scientific article published on 21 February 2016

Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy for the definitive treatment of cervix cancer

scientific article published on 14 May 2010

Consensus statement for brachytherapy for the treatment of medically inoperable endometrial cancer

scientific article

Consolidative abdominopelvic radiotherapy after surgery and carboplatin/paclitaxel chemotherapy for epithelial ovarian cancer

scientific article

Correlations between dynamic contrast-enhanced magnetic resonance imaging–derived measures of tumor microvasculature and interstitial fluid pressure in patients with cervical cancer

article

Developing a prognostic micro-RNA signature for human cervical carcinoma

scientific article published on 16 April 2015

Diffusion-weighted MRI in cervical cancer

scientific article published on 12 January 2008

Do single and partnered women with gynecologic cancer differ in types and intensities of illness- and treatment-related psychosocial concerns? A pilot study

scientific article published on 02 August 2007

Does a groin node dissection in vulvar cancer affect groin recurrence and overall survival?: Results from a population-based cohort study

scientific article published on 16 November 2016

Dosimetric comparison of intensity-modulated, conformal, and four-field pelvic radiotherapy boost plans for gynecologic cancer: a retrospective planning study.

scientific article

Dosimetrically triggered adaptive intensity modulated radiation therapy for cervical cancer

scientific article published on 8 July 2014

Dysregulated PTEN-PKB and negative receptor status in human breast cancer

scientific article

Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX

scientific article published in October 2007

Effect of filgrastim (G-CSF) during chemotherapy and abdomino-pelvic radiation therapy in patients with ovarian carcinoma ⬇️

scientific article published on July 1, 1998

Endometrial Cancer Risk Is Associated with Variants of the Mismatch Repair Genes MLH1 and MSH2

article

Establishing the Role of Stereotactic Ablative Body Radiotherapy in Early-Stage Breast Cancer

scientific article published in February 2018

Estimating hypoxic status in human tumors: a simulation using Eppendorf oxygen probe data in cervical cancer patients.

scientific article

Evaluation of variability in seroma delineation between clinical specialist radiation therapist and radiation oncologist for adjuvant breast irradiation

scientific article published on 19 September 2011

Excellence in Radiation Research for the 21st Century (EIRR21): description of an innovative research training program

scientific article published on 18 April 2012

Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation

scientific article published in July 2002

External Beam Radiation Therapy and Brachytherapy for Cervical Cancer: The Experience of the National Centre for Radiotherapy in Accra, Ghana

scientific article published on 21 December 2017

Factors influencing arm and axillary symptoms after treatment for node negative breast carcinoma

scientific article published in March 2003

Follow-up for cervical cancer: a Program in Evidence-Based Care systematic review and clinical practice guideline update.

scientific article published on 13 April 2016

Follow-up for women after treatment for cervical cancer: a systematic review

scientific article published on 26 June 2009

Gene expression profiling in cervical cancer: an exploration of intratumor heterogeneity

scientific article published on October 2006

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian small cell cancers

scientific article

Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation

scientific article published on 25 October 2011

Heterogeneity and power in clinical biomarker studies

scientific article published on 9 February 2009

Heterogeneity of polarographic oxygen tension measurements in cervix cancer: an evaluation of within and between tumor variability, probe position, and track depth

scientific article published on 01 September 1997

Heterogeneity of tumor oxygenation: relationship to tumor necrosis, tumor size, and metastasis

scientific article published in November 1998

High tumor interstitial fluid pressure identifies cervical cancer patients with improved survival from radiotherapy plus cisplatin versus radiotherapy alone

article

Hybrid adaptive radiotherapy with on-line MRI in cervix cancer IMRT.

scientific article

Hypoxia and Predicting Radiation Response

scientific article published on 15 May 2015

Identification of a Low-Risk Luminal A Breast Cancer Cohort That May Not Benefit From Breast Radiotherapy

scientific article published on 11 May 2015

In Regard to Ishikawa et al.: Cyclooxygenase-2 Impairs Treatment Effect of Radiotherapy for Cervical Cancer by Inhibition of Radiation-Induced Apoptosis (Int J Radiat Oncol Biol Phys 2006;66:1347–1355)

scientific article published on 01 July 2007

In Reply to Smith and Eifel

scientific article published on 01 February 2014

Intensity-modulated Radiotherapy in the Treatment of Gynaecological Cancers ⬇️

scientific article published on June 13, 2012

Inter- and Intrafractional Tumor and Organ Movement in Patients With Cervical Cancer Undergoing Radiotherapy: A Cinematic-MRI Point-of-Interest Study

article

Interim cosmetic and toxicity results from RAPID: a randomized trial of accelerated partial breast irradiation using three-dimensional conformal external beam radiation therapy

scientific article published on 8 July 2013

Intermediate dose–volume parameters and the development of late rectal toxicity after MRI-guided brachytherapy for locally advanced cervix cancer

article

Interrelationship of proliferation and hypoxia in carcinoma of the cervix

scientific article published in January 2000

Interstitial Fluid Pressure in Cervical Cancer

scientific article published on 01 October 2001

Interstitial fluid pressure in tumors: therapeutic barrier and biomarker of angiogenesis.

scientific article published on December 2008

Interstitial permeability and elasticity in human cervix cancer

scientific article published on 03 December 2007

Intratumoral sickling in a patient with cervix cancer and sickle trait: effect on blood flow and oxygenation

scientific article

Is abdomino-pelvic radiation therapy the optimal treatment for completely resected stage I and II high risk ovarian cancer?

scientific article published on January 1997

Late renal function following whole abdominal irradiation

scientific article

Local control with conventional and hypofractionated adjuvant radiotherapy after breast-conserving surgery for ductal carcinoma in-situ

article

Long-term performance of interstial fluid pressure and hypoxia as prognostic factors in cervix cancer

scientific article

Long-term results of hypofractionated radiation therapy for breast cancer

scientific article published in February 2010

Magnetic Resonance Imaging-Guided Intracavitary Brachytherapy for Cancer of the Cervix

article

MiR-449a promotes breast cancer progression by targeting CRIP2.

scientific article published on 26 February 2016

MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

scientific article published on 4 July 2013

MicroRNA-301 mediates proliferation and invasion in human breast cancer.

scientific article

Molecular targeted agents combined with chemo-radiation in the treatment of locally advanced cervix cancer.

scientific article published on May 2008

Neither ovariectomy nor progestin treatment prevents endometrial neoplasia in pten+/- mice.

scientific article published on 28 November 2007

Omission of Breast Radiotherapy in Low-risk Luminal A Breast Cancer: Impact on Health Care Costs

scientific article

Outcome of patients with unfavorable optimally cytoreduced ovarian cancer treated with chemotherapy and whole abdominal radiation

scientific article published on 01 April 1991

Oxygenation predicts radiation response and survival in patients with cervix cancer

scientific article

Patient, tumor, and health system factors affecting groin node dissection rates in vulvar carcinoma: A population-based cohort study

scientific article published on 16 October 2015

Pelvic Radiotherapy for Cancer of the Cervix: Is What You Plan Actually What You Deliver?

scientific article published on 01 May 2009

Pelvic lymph node topography for radiotherapy treatment planning from ferumoxtran-10 contrast-enhanced magnetic resonance imaging

scientific article

Phase 1 study of tirapazamine in combination with radiation and weekly cisplatin in patients with locally advanced cervical cancer

scientific article published on July 2010

Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCIC IND-148.

scientific article published on 30 June 2008

Phylloides tumor of the breast: A report of 14 cases

scientific article published on 01 June 1994

Postoperative radiotherapy improves local control and survival in patients with uterine leiomyosarcoma.

scientific article published on 24 May 2013

Predictors of adverse cosmetic outcome in the RAPID trial: an exploratory analysis.

scientific article published on April 2015

Predictors of breast radiotherapy plan modifications: quality assurance rounds in a large cancer centre

scientific article

Prognostic Significance of Human Papilloma Virus and p16 Expression in Patients with Vulvar Squamous Cell Carcinoma who Received Radiotherapy.

scientific article published on 12 February 2018

Prognostic factors in patients with cervix cancer treated by radiation therapy: results of a multiple regression analysis

scientific article published in May 1995

Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma

scientific article published in January 2001

Proliferation measurements with flow cytometry Tpot in cancer of the uterine cervix: correlation between two laboratories and preliminary clinical results

scientific article published in July 1995

Proliferation parameters in epidermoid carcinomas of the anal canal

article

Prospective comparison of breast pain in patients participating in a randomized trial of breast-conserving surgery and tamoxifen with or without radiotherapy

scientific article

Quantitative coronary angiography findings of patients who received previous breast radiotherapy

scientific article published on 16 April 2011

Radiation therapy quality-of-care indicators for locally advanced cervical cancer: A consensus guideline

scientific article published on 28 January 2016

Rapid Automated Treatment Planning Process to Select Breast Cancer Patients for Active Breathing Control to Achieve Cardiac Dose Reduction

Relations between non-protein sulfydryl levels in the nucleus and cytoplasm, tumor oxygenation, and clinical outcome of patients with uterine cervical carcinoma

scientific article published in January 2005

Results of Radical Radiotherapy for Recurrent Endometrial Cancer

scientific article published on 01 April 2000

Role of adjuvant radiotherapy in granulosa cell tumors of the ovary

scientific article published on 14 May 2010

Role of mitomycin C in the development of late bowel toxicity foloowing chemoradiation for locally advanced carcinoma of the cervix

article

Slogans and donor pages of cancer centres: do they convey discordant messages?

scientific article published on 01 April 2018

Sorafenib Increases Tumor Hypoxia in Cervical Cancer Patients Treated With Radiation Therapy: Results of a Phase 1 Clinical Study.

scientific article published on 18 September 2015

Stage II endometrial carcinoma: prognostic factors and risk classification in 170 patients

scientific article published on 01 July 2002

Systematic review of adjuvant care for women with Stage I ovarian carcinoma.

scientific article published in November 2004

TARGIT-R (Retrospective): North American Experience with Intraoperative Radiation Using Low-Kilovoltage X-Rays for Breast Cancer

scientific article

Tamoxifen and risk of endometrial cancer

scientific article

Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer

scientific article published in September 2004

Tamoxifen with radiotherapy compared with Tamoxifen alone in elderly women with early-stage breast cancer treated with breast conserving surgery: A systematic review and meta-analysis

scientific article

Technique adaptation, strategic replanning, and team learning during implementation of MR-guided brachytherapy for cervical cancer.

scientific article

Technological advances in radiotherapy for cervical cancer

scientific article published on September 2011

The Added Value of Pathology Review in Vulvar Cancer: Results From a Population-based Cohort Study

scientific article

The Effect of Smoking on Tumour Oxygenation and Treatment Outcome in Cervical Cancer

article

The Role of Adjuvant Radiotherapy in Carcinoma of the Endometrium—Results in 550 Patients with Pathologic Stage I Disease

scientific article published on 01 August 1998

The Role of Elective Para-aortic Lymph Node Irradiation in Patients with Locally Advanced Cervical Cancer

scientific article published on 04 September 2014

The activity of letrozole in patients with advanced or recurrent endometrial cancer and correlation with biological markers--a study of the National Cancer Institute of Canada Clinical Trials Group.

scientific article published on July 2004

The clinical significance of hypoxia in human cancers

scientific article published in March 2015

The effect of local breast radiotherapy on circulating CD34(+) cells

scientific article published on 11 February 2011

The effect of treatment duration in the local control of cervix cancer

scientific article published on 01 December 1992

The effect of treatment duration on local control of squamous carcinoma of the tonsil and carcinoma of the cervix

The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure

scientific article published in July 2004

The impact of active breathing control on internal mammary lymph node coverage and normal tissue exposure in breast cancer patients planned for left-sided postmastectomy radiation therapy

scientific article published on 7 December 2016

The psychosocial impact of cervical cancer among affected women and their partners

scientific article published in September 2005

The rapid uptake of concurrent chemotherapy for cervix cancer patients treated with curative radiation

scientific article published on 18 January 2006

The relationship between elevated interstitial fluid pressure and blood flow in tumors: a bioengineering analysis

article

The significance of tumoral ERCC1 status in patients with locally advanced cervical cancer treated with chemoradiation therapy: a multicenter clinicopathologic analysis

scientific article published on 24 July 2012

Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial

scientific article published on 7 July 2016

Treating vulvar cancer in the new millennium: Are patients receiving optimal care?

scientific article published on 29 January 2008

Treatment of early epithelial ovarian cancer with chemotherapy and abdominopelvic radiotherapy: results of a prospective treatment protocol

article

Trends in the utilization of brachytherapy in cervical cancer in the United States

scientific article published on 9 July 2013

Tumor and normal tissue dosimetry changes during MR-guided pulsed-dose-rate (PDR) brachytherapy for cervical cancer

scientific article published on 27 March 2013

Tumor factors predictive of response to hypofractionated radiotherapy in a randomized trial following breast conserving therapy

scientific article published on 20 February 2014

Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer

scientific article published in February 2002

Tumor proliferation and apoptosis in human uterine cervix carcinoma I: correlations between variables.

scientific article published on January 1999

Tumor size and oxygenation are independent predictors of nodal diseases in patients with cervix cancer

scientific article published in November 2001

Tumour proliferation and apoptosis in human uterine cervix carcinoma II: correlations with clinical outcome

article

Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis

scientific article published in February 2004

Use of alternative therapy in postmenopausal breast cancer patients treated with tamoxifen after surgery

scientific article published in November 2004

Uterine papillary serous carcinoma: evaluation of multimodality treatment with abdominopelvic radiotherapy and chemotherapy.

scientific article

Variability in clinical target volume delineation for intensity modulated radiation therapy in 3 challenging cervix cancer scenarios

scientific article published on 02 July 2015

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