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List of works by Marina Pajic

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

scientific article published in October 2017

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

scientific article published in May 2011

ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumors

scientific article published on 03 August 2018

Adjuvant chemotherapy in elderly patients with pancreatic cancer.

scientific article

An analysis of reported motivational orientation in students undertaking doctoral studies in the biomedical sciences

scientific article

BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma

scientific article published on 03 March 2018

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

scientific article published on 31 August 2013

Clinical and pathologic features of familial pancreatic cancer

scientific article published on 14 October 2014

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

scientific article published on May 2004

Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

scientific article published on 26 May 2017

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

scientific article published on 20 June 2016

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma

scientific article published on 16 May 2014

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

scientific article published on 9 May 2014

Genomic analyses identify molecular subtypes of pancreatic cancer

scientific article published on 24 February 2016

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

scientific article published on 2 March 2016

Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater

scientific article published on 25 February 2013

Hypermutation In Pancreatic Cancer

scientific article

Imaging fibrosis in pancreatic cancer using second harmonic generation

scientific article published on 01 March 2015

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors

scientific article

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

scientific article

Lost in translation: returning germline genetic results in genome-scale cancer research

scientific article

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

scientific article published on 01 June 2020

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

scientific article published on 30 January 2017

Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer

article

Nucleus pulposus cellular longevity by telomerase gene therapy

scientific article published in May 2007

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

scientific article

Personalising pancreas cancer treatment: When tissue is the issue

scientific article

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial

scientific article published on May 2015

Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer

scientific article published on 30 November 2018

Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes

scientific article published on 23 April 2011

Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction

scientific article

Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.

scientific article published on 26 December 2017

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling

scientific article published on 3 June 2016

Returning individual research results for genome sequences of pancreatic cancer

scientific article

Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarinoma Invasion and Tumor Growth.

scientific article published on 18 April 2018

Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities

scientific article

SOX9 regulates ERBB signalling in pancreatic cancer development.

scientific article published on 21 October 2014

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials

scientific article

Selected alkylating agents can overcome drug tolerance of G0-like tumor cells and eradicate BRCA1-deficient mammary tumors in mice

scientific article

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

scholarly article

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan

scientific article

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.

scientific article published on 27 March 2017

Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma

scientific article published on 4 August 2009

Somatic point mutation calling in low cellularity tumors.

scientific article

Studying drug resistance using genetically engineered mouse models for breast cancer

scientific article

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer

scientific article published on 28 October 2017

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

scientific article published on 08 October 2020

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy.

scientific article published on 3 October 2017

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

scientific article published on 05 August 2019

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma

article published in 2018

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models

scientific article published on 22 August 2016

The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment

scientific article

The epigenetic agents suberoylanilide hydroxamic acid and 5‑AZA‑2' deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo.

scientific article

The prognostic and predictive value of serum CA19.9 in pancreatic cancer

scientific article published on 11 January 2012

The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome

scientific article

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.

scientific article published on 4 December 2017

Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.

scientific article published on 3 October 2017

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

scientific article published in April 2017

Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo

scientific article

Understanding pancreatic cancer genomes

scientific article published on August 2013

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

Whole-genome landscape of pancreatic neuroendocrine tumours.

scientific article published on 15 February 2017

miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense

scientific article

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles

scientific article

∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

scientific article published on 17 January 2018

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