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List of works by Rupert M Pearse

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Perioperative myocardial injury in patients receiving cardiac output-guided haemodynamic therapy: a substudy of the OPTIMISE Trial

scientific article
Organisational failures in urgent and emergency surgery. A potential peri-operative risk factor

scientific article
Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

scientific article
Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery

scientific article published on 11 March 2016
Acute kidney injury and mortality 1 year after major non-cardiac surgery.

scientific article published on 20 February 2017
Regional variation in critical care provision and outcome after high-risk surgery

scientific article published on 23 July 2015
Should we use central venous saturation to guide management in high-risk surgical patients?

scientific article published on January 2006
Variation in haemodynamic monitoring for major surgery in European nations: secondary analysis of the EuSOS dataset.

scientific article
Intensive Care after High-risk Surgery: What's in a Name?

scientific article published on 29 January 2016
Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow

scientific article published on 28 March 2013
Current use of vasopressors in septic shock

scientific article published on 30 January 2019
Preoperative renal dysfunction and mortality after non-cardiac surgery.

scientific article published on 27 June 2016
Pathways to professionalism? Quality improvement, care pathways, and the interplay of standardisation and clinical autonomy

scientific article published on 21 June 2017
The use of early intervention to prevent postoperative complications.

scientific article published on August 2009
Changes in gene expression following trauma are related to the age of transfused packed red blood cells.

scientific article published on March 2015
Cost-effectiveness of a cardiac output-guided haemodynamic therapy algorithm in high-risk patients undergoing major gastrointestinal surgery

scientific article
American Society of Anesthesiologists Score: still useful after 60 years? Results of the EuSOS Study

scientific article
Peri-operative hemodynamic therapy: only large clinical trials can resolve our uncertainty

scientific article published on June 3, 2011
Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients.

scientific article published in July 2017
Dynamic preload markers to predict fluid responsiveness during and after major gastrointestinal surgery: an observational substudy of the OPTIMISE trial.

scientific article published on 11 December 2014
Preoperative abnormalities in serum sodium concentrations are associated with higher in-hospital mortality in patients undergoing major surgery.

scientific article published on January 2016
Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry

scientific article
Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery.

scientific article
EuSOS: European Surgical Outcomes Study

article published in 2011
Non-invasive ventilation to avoid tracheal intubation in a patient with Guillain-Barré syndrome

scientific article published in December 2003
Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model.

scientific article published on 26 February 2018
Effect of day of the week on short- and long-term mortality after emergency general surgery

scientific article published on 21 March 2017
Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study

scientific article
Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usua

scientific article published on 15 January 2019
The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study

scientific article published on 01 September 2018
Improving detection of patient deterioration in the general hospital ward environment

scientific article published on 22 February 2018
Observational study of the effects of age, diabetes mellitus, cirrhosis and chronic kidney disease on sublingual microvascular flow.

scientific article published on 09 April 2013
Improving care at scale: process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial)

scientific article published on 13 November 2018
Current research priorities in perioperative intensive care medicine.

scientific article published on 08 June 2017
Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery

scientific article published in PLoS ONE
Do integrated care pathways have a place in critical care?

scientific article published on December 2012
A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study.

scientific article published on 26 October 2017
Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma.

scientific article published on November 2015
Using oxygen delivery targets to optimize resuscitation in critically ill patients.

scientific article published on June 2010
Mortality after surgery in Europe - Authors' reply

scientific article published in February 2013
Pre-operative fasting and administration of regular medications in adult patients presenting for elective surgery. Has the new evidence changed practice?

scientific article
Peri-operative troponin monitoring using a prototype high-sensitivity cardiac troponin I (hs-cTnI) assay: comparisons with hs-cTnT and contemporary cTnI assays

scientific article published on 18 September 2013
Association of preoperative anaemia with postoperative morbidity and mortality: an observational cohort study in low-, middle-, and high-income countries

scientific article published on 25 October 2018
Preoperative N-Terminal Pro-B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery: A Cohort Study

scientific article published on 24 December 2019
The incidence of myocardial injury following post-operative Goal Directed Therapy

scientific article published on 19 March 2007
Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients

scientific article published on 14 May 2012
ICU admission after surgery: who benefits?

scientific article
Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery

scientific article published on 02 October 2018
An analysis of admission, discharge and bed occupancy of stroke patients aged 65 and over in English hospitals.

scientific article
The Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial. Report of the protocol for a pragmatic randomized controlled trial of CPAP to prevent respiratory complications and improve survival following major abdominal surge

scientific article

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