List of works - Scott A. Wildman

A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility

scientific article published on 01 June 2017

A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings

scientific article published on 05 September 2019

Approaches to virtual screening and screening library selection.

scientific article

Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.

scientific article published on 29 January 2016

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase

scientific article published on 22 August 2011

Evaluation of ligand overlap by atomic parameters

scientific article published on 01 March 2001

High-throughput identification of putative receptors for cancer-binding peptides using biopanning and microarray analysis.

scientific article

Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence

scientific article published on 10 June 2016

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

scientific article published on 28 December 2015

Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer

scientific article published on 9 October 2014

Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.

scientific article

Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.

scientific article published on 27 June 2017

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii

scientific article

Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin

scientific article published on 18 July 2019

Practical Model Selection for Prospective Virtual Screening

scientific article published on 18 December 2018

Predicting kinase inhibitors using bioactivity matrix derived informer sets

scientific article published on 05 August 2019

Predicting kinase selectivity profiles using Free-Wilson QSAR analysis

scientific article

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics

scientific article published on 14 May 2018

Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.

scientific article published on 4 April 2015

The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.

scientific article

Three-dimensional molecular descriptors and a novel QSAR method

scientific article published on 01 December 2002

Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers.

scientific article published on 21 July 2016

α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer

scientific article published on 17 February 2016

List of works by Scott A. Wildman

A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility

A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings

Approaches to virtual screening and screening library selection.

Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase

Evaluation of ligand overlap by atomic parameters

High-throughput identification of putative receptors for cancer-binding peptides using biopanning and microarray analysis.

Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer

Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.

Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii

Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin

Practical Model Selection for Prospective Virtual Screening

Predicting kinase inhibitors using bioactivity matrix derived informer sets

Predicting kinase selectivity profiles using Free-Wilson QSAR analysis

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics

Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.

The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.

Three-dimensional molecular descriptors and a novel QSAR method

Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers.

α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer