List of works - Nicklas Raun Jacobsen

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges

scientific article published on January 2016

A real-time PCR assay for the specific identification of serotype O:9 of Yersinia enterocolitica

scientific article published on 19 April 2005

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories

scientific article published on 7 August 2015

Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials

scientific article published on 30 March 2016

Bioaccumulation and ecotoxicity of carbon nanotubes

scientific article published on 13 September 2013

Biodistribution of Carbon Nanotubes in Animal Models

scientific article published on 16 November 2016

Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation

scientific article

Black tattoo inks induce reactive oxygen species production correlating with aggregation of pigment nanoparticles and product brand but not with the polycyclic aromatic hydrocarbon content.

scientific article

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver ⬇️

scientific article published on February 2, 2012

Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung.

scientific article published on 29 June 2012

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression

scientific article published in December 2013

Carbon black nanoparticles and other problematic constituents of black ink and their potential to harm tattooed humans

scientific article

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation

scientific article published on 6 November 2015

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

scientific article published on 22 January 2015

Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice

scientific article

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor

scientific article

DNA damage following pulmonary exposure by instillation to low doses of carbon black (Printex 90) nanoparticles in mice

scientific article

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.

scientific article published on 14 March 2015

Development of a standard operating procedure for the DCFH2-DA acellular assessment of reactive oxygen species produced by nanomaterials

scientific article

Diesel exhaust particles are mutagenic in FE1-MutaMouse lung epithelial cells

scientific article

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

scientific article

Enrichment followed by quantitative PCR both for rapid detection and as a tool for quantitative risk assessment of food-borne thermotolerant campylobacters

scientific article published on June 2004

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition

scientific article

FIB-SEM imaging of carbon nanotubes in mouse lung tissue

scientific article

Genotoxicity of unmodified and organo-modified montmorillonite.

scientific article published on 28 April 2010

Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells

scientific article

Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air.

scientific article

Glutathione metabolism and dimorphism in Aureobasidium pullulans

scientific article published in January 2001

Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO2 nanoparticles

scientific article published on 12 February 2016

In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT

scientific article published on 23 July 2021

Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells

scientific article

Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide

scientific article

Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers

scientific article published on 07 June 2011

Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers

scientific article published on 13 October 2011

Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice

scientific article

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

scientific article

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

scientific article published on 29 December 2014

Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals

scientific article published on 05 September 2014

Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO(2)

scientific article

Modest vasomotor dysfunction induced by low doses of C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis

scientific article

Monocyte adhesion induced by multi-walled carbon nanotubes and palmitic acid in endothelial cells and alveolar-endothelial co-cultures

scientific article published on 12 June 2015

Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of Basal cell carcinoma.

scientific article published on November 2002

Mutagenicity of Carbon Nanomaterials

scientific article published on 01 February 2011

Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black

scientific article published on 20 October 2010

Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

scientific article published on 2 February 2012

No association between OGG1 Ser326Cys polymorphism and breast cancer risk

scientific article published on 01 February 2003

No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer.

scientific article

No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro

scientific article published on 17 May 2016

Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter

scientific article published on 23 September 2010

Oxidatively damaged DNA in rats exposed by oral gavage to C60 fullerenes and single-walled carbon nanotubes

scientific article

Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk

scientific article

Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease

scientific article

Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice

scientific article published on 3 January 2018

Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring

scientific article

Pulmonary exposure to carbon black nanoparticles and vascular effects

scientific article

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

scientific article published on April 2013

Pulmonary toxicity of synthetic amorphous silica - effects of porosity and copper oxide doping

scientific article published on 11 November 2020

Role of oxidative stress in carbon nanotube-generated health effects

scientific article published on 12 September 2014

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice

scientific article

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

scientific article published on 11 December 2014

Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells

scientific article

Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer

scientific article published on February 2004

Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay

scientific article published on 17 October 2013

Vascular Effects of Multiwalled Carbon Nanotubes in Dyslipidemic ApoE−/− Mice and Cultured Endothelial Cells

scientific article published on 15 January 2014

Weight of evidence analysis for assessing the genotoxic potential of carbon nanotubes

scientific article published on 22 September 2017

List of works by Nicklas Raun Jacobsen

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges

A real-time PCR assay for the specific identification of serotype O:9 of Yersinia enterocolitica

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories

Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials

Bioaccumulation and ecotoxicity of carbon nanotubes

Biodistribution of Carbon Nanotubes in Animal Models

Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation

Black tattoo inks induce reactive oxygen species production correlating with aggregation of pigment nanoparticles and product brand but not with the polycyclic aromatic hydrocarbon content.

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver ⬇️

Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung.

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression

Carbon black nanoparticles and other problematic constituents of black ink and their potential to harm tattooed humans

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor

DNA damage following pulmonary exposure by instillation to low doses of carbon black (Printex 90) nanoparticles in mice

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.

Development of a standard operating procedure for the DCFH2-DA acellular assessment of reactive oxygen species produced by nanomaterials

Diesel exhaust particles are mutagenic in FE1-MutaMouse lung epithelial cells

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

Enrichment followed by quantitative PCR both for rapid detection and as a tool for quantitative risk assessment of food-borne thermotolerant campylobacters

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition

FIB-SEM imaging of carbon nanotubes in mouse lung tissue

Genotoxicity of unmodified and organo-modified montmorillonite.

Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells

Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air.

Glutathione metabolism and dimorphism in Aureobasidium pullulans

Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO2 nanoparticles

In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT

Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells

Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide

Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers

Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers

Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals

Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO(2)

Modest vasomotor dysfunction induced by low doses of C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis

Monocyte adhesion induced by multi-walled carbon nanotubes and palmitic acid in endothelial cells and alveolar-endothelial co-cultures

Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of Basal cell carcinoma.

Mutagenicity of Carbon Nanomaterials

Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black

Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

No association between OGG1 Ser326Cys polymorphism and breast cancer risk

No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer.

No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro

Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter

Oxidatively damaged DNA in rats exposed by oral gavage to C60 fullerenes and single-walled carbon nanotubes

Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk

Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease

Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice

Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring

Pulmonary exposure to carbon black nanoparticles and vascular effects

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

Pulmonary toxicity of synthetic amorphous silica - effects of porosity and copper oxide doping

Role of oxidative stress in carbon nanotube-generated health effects

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells

Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer

Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay

Vascular Effects of Multiwalled Carbon Nanotubes in Dyslipidemic ApoE−/− Mice and Cultured Endothelial Cells

Weight of evidence analysis for assessing the genotoxic potential of carbon nanotubes

XRCC3 polymorphisms and risk of lung cancer