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List of works by José Rueff

8,15-epoxylabdane and norlabdane diterpenoids from Eragrostis viscosa.

scientific article published on 26 February 2010

A personally guided tour on some of our data with the Ames assay-A tribute to Professor Bruce Ames

scientific article published on 09 September 2019

APC intragenic haplotypes in familial adenomatous polyposis.

scientific article

Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer ⬇️

scientific article published on May 1, 1998

Activation of promutagens by porphyrinic biomimetic systems

scientific article published in October 1992

Alkylating potential of oxetanes.

scientific article published in July 2010

Altered human CYP3A4 activity caused by Antley-Bixler syndrome-related variants of NADPH-cytochrome P450 oxidoreductase measured in a robust in vitro system

scientific article published on 17 January 2012

Aneuploidy induced in lymphocytes of parents of trisomic 21 children.

scientific article published in January 2001

Aromatic DNA adduct levels in coke oven workers: correlation with polymorphisms in genes GSTP1, GSTM1, GSTT1 and CYP1A1.

scientific article published in May 2002

Assessment of the adaptive response induced by quercetin using the MNCB peripheral blood human lymphocytes assay

scientific article published on 01 January 2000

Association of Polymorphisms in ERCC2 Gene with Non-Familial Thyroid Cancer Risk

article

Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.

scientific article published on 25 September 2009

Association of p53 genomic instability with the glutathione S-transferase null genotype in gastric cancer in the Portuguese population

scientific article

Asynchronous DNA replication detected by fluorescence in situ hybridisation as a possible indicator of genetic damage in human lymphocytes.

scientific article published in February 2008

Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51.

scientific article

Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17beta1, COMT and MnSOD): possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed

scientific article published on 01 October 2006

Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint

scientific article published on January 2016

Catechols from abietic acid synthesis and evaluation as bioactive compounds.

scientific article published on April 2003

Chemical features of flavonols affecting their genotoxicity. Potential implications in their use as therapeutical agents.

scientific article

Combined effects of glutathione S-transferase polymorphisms and thyroid cancer risk

scientific article published in May 2004

Cytochrome P450 expression system for high-throughput real-time detection of genotoxicity: Application to the study of human CYP1A2 variants

scientific article

Cytogenetic alterations and oxidative stress in thyroid cancer patients after iodine-131 therapy

scientific article published on 01 January 2000

Cytogenetic and DNA damage on workers exposed to styrene.

scientific article published on 20 August 2010

Cytogenetic and molecular biomonitoring of a Portuguese population exposed to pesticides

article

DNA damage and susceptibility assessment in industrial workers exposed to styrene.

scientific article published in January 2012

DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells

scientific article published on 21 May 2012

DNA polymorphisms as modulators of genotoxicity and cancer.

scientific article

DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes polymorphisms

scientific article

DNA strand breaks and chromosomal aberrations induced by H2O2 and 60Co gamma-radiation

scientific article published on 01 October 1993

DNA-PK inhibitor wortmannin enhances DNA damage induced by bleomycin in V79 Chinese hamster cells

scientific article published on January 2002

Development of imatinib and dasatinib resistance: dynamics of expression of drug transportersABCB1, ABCC1, ABCG2, MVP, and SLC22A1

article

Development of pyridine-containing macrocyclic copper(II) complexes: potential role in the redox modulation of oxaliplatin toxicity in human breast cells

scientific article published on 20 June 2012

Down syndrome and microRNAs

scientific article published on 17 November 2017

Dynamics of Expression of Drug Transporters: Methods for Appraisal

scientific article published on January 2016

Effect of a poly(ADP-ribose) polymerase inhibitor on DNA breakage and cytotoxicity induced by hydrogen peroxide and gamma-radiation

scientific article published on 01 January 1996

Effect of kidney disease on glucose handling (including genetic defects) ⬇️

scientific article published on March 1, 2011

Effects of polymorphic DNA genes involved in BER and caspase pathways on the clinical outcome of myeloproliferative neoplasms under treatment with hydroxyurea

article

Elevated levels of DNA-protein crosslinks and micronuclei in peripheral lymphocytes of tannery workers exposed to trivalent chromium.

scientific article published in January 2003

Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.

scientific article

Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: comparison of three types of expression systems

scientific article published on 01 February 1999

Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies

scientific article published on 01 April 1999

Estragole: a weak direct-acting food-borne genotoxin and potential carcinogen.

scientific article published on 3 May 2012

Evaluation of some biomonitoring markers in occupationally exposed populations to acrylonitrile

scientific article published in January 1996

Evaluation of the genotoxic effects of the boron neutron capture reaction in human melanoma cells using the cytokinesis block micronucleus assay

scientific article

Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.

scientific article published in May 1998

Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting

scientific article

Fast and reliable screening of mutations in human tumors: use of multiple fluorescence-based long linker arm nucleotides assay (mf-LLA)

scientific article published on 01 June 1999

Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression.

scientific article published on 2 February 2010

GSTM1, GSTT1, and GSTP1 genotypes and the genotoxicity of hydroquinone in human lymphocytes

scientific article

Gene Symbol: SLC55A2. Disease: familial renal glucosuria.

scientific article published on July 2004

Genetic Polymorphisms in Detoxification and DNA Repair Genes and Susceptibility to Glycidamide-Induced DNA Damage

article

Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants

scientific article published on 01 January 2017

Genetic toxicology of flavonoids: the role of metabolic conditions in the induction of reverse mutation, SOS functions and sister-chromatid exchanges

scientific article

Genomics and cancer drug resistance.

scientific article published on April 2012

Genotoxic alkenylbenzene flavourings, a contribution to risk assessment

scientific article published on 18 June 2018

Genotoxic and apoptotic activities of the food flavourings myristicin and eugenol in AA8 and XRCC1 deficient EM9 cells.

scientific article published on 16 November 2010

Genotoxic effects of doxorubicin in cultured human lymphocytes with different glutathione S-transferase genotypes

scientific article published on 26 May 2011

Genotoxic flavonoids and red wine: a possible role in stomach carcinogenesis.

scientific article published on December 1994

Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol.

scientific article published on 4 April 2006

Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells.

scientific article published on December 1994

Genotoxicity of instant coffee and of some phenolic compounds present in coffee upon nitrosation.

scientific article published in January 2000

Genotoxicity of nitrosated red wine and of the nitrosatable phenolic compounds present in wine: tyramine, quercetin and malvidine-3-glucoside.

scientific article

Genotoxicity of quercetin in the micronucleus assay in mouse bone marrow erythrocytes, human lymphocytes, V79 cell line and identification of kinetochore-containing (CREST staining) micronuclei in human lymphocytes

scientific article published on June 1995

Glutathione S-transferase mu polymorphism and susceptibility to lung cancer in the Portuguese population

scientific article published on 01 January 1996

Glycidamide genotoxicity modulated by Caspases genes polymorphisms

scientific article published on 5 April 2016

Histologic and genetic assessment of explanted allograft valves

scientific article published on 01 August 1995

Human cytochrome P450 oxidoreductase deficiency caused by the Y181D mutation: molecular consequences and rescue of defect.

scientific article

Human sulfotransferase 1A1-dependent mutagenicity of 12-hydroxy-nevirapine: the missing link?

scientific article published on 13 October 2014

Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley-Bixler syndrome variants of cytochrome P450 oxidoreductase.

scientific article published on 20 April 2008

Induction of an adaptive response to quercetin, mitomycin C and hydrogen peroxide by low doses of quercetin in V79 Chinese hamster cells ⬇️

scientific article published on November 1, 1997

Induction of chromosomal aberrations by phenolic compounds: possible role of reactive oxygen species.

scientific article published in September 2003

Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulator of patulin clastogenicity

scientific article

Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide

scientific article published on 31 January 2013

Influence of S9 mix in the induction of SOS system by quercetin

scientific article published on 01 May 1987

Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.

scientific article

Integration of HIV in the Human Genome: Which Sites Are Preferential? A Genetic and Statistical Assessment.

scientific article published on 12 May 2016

Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding

scientific article published on 11 September 2020

Isolation and prevalidation of an Escherichia coli tester strain for the use in mechanistic and metabolic studies of genotoxins

scientific article published in April 1994

Lipoperoxidation products and thiol antioxidants in chromium exposed workers.

scientific article published on 28 June 2005

MX100, a new Escherichia coli tester strain for use in genotoxicity studies.

scientific article

Macrocyclic copper(II) complexes: superoxide scavenging activity, structural studies and cytotoxicity evaluation.

scientific article published on 11 February 2007

Mechanisms of induction of chromosomal aberrations by hydroquinone in V79 cells.

scientific article published in November 2003

Mechanisms of myricetin mutagenicity in V79 cells: involvement of radicalar species

scientific article published on 01 January 1996

Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells

scientific article published on November 2013

Menopausal age and XRCC1 gene polymorphisms: role in breast cancer risk

scientific article published on 01 January 2007

Metabolism of galangin by rat cytochromes P450: relevance to the genotoxicity of galangin ⬇️

scientific article published on October 24, 1997

Methods for Studying MicroRNA Expression and Their Targets in Formalin-Fixed, Paraffin-Embedded (FFPE) Breast Cancer Tissues.

scientific article published on January 2016

MicroRNAs and Cancer Drug Resistance

scientific article published on January 2016

Micronuclei Formation upon Radioiodine Therapy for Well-Differentiated Thyroid Cancer: The Influence of DNA Repair Genes Variants

scientific article published on 17 September 2020

Monitoring of exposure to acrylonitrile by determination of N-(2-cyanoethyl)valine at the N-terminal position of haemoglobin.

scientific article published on December 1996

Multiplex PCR-single-base extension genotyping of multiple glutathione S-transferase polymorphisms.

scientific article

Mutagenic activity in the wine-making process: correlations with rutin and quercetin levels

scientific article published in July 1990

Mutagenic activity of glycine upon nitrosation in the presence of chloride and human gastric juice: a possible role in gastric carcinogenesis

scientific article published in January 1996

Mutagenicity in urine of workers in naval industry

scientific article published on 01 January 1982

Mutagenicity of kaempferol in V79 cells: The role of cytochromes P450 ⬇️

scientific article published on January 1, 1996

Mutagenicity of rutin and the glycosidic activity of cultured cell-free microbial preparations of human faeces and saliva

scientific article published on 01 July 1989

Mutagenicity, carcinogenicity, and teratogenicity of acrylonitrile.

scientific article

Myristicin from nutmeg induces apoptosis via the mitochondrial pathway and down regulates genes of the DNA damage response pathways in human leukaemia K562 cells.

scientific article published on 29 April 2014

Naturally contaminated shellfish samples: quantification of diarrhetic shellfish poisoning toxins in unhydrolysed and hydrolysed extracts and cytotoxicity assessment.

scientific article published on October 2010

Newneo-Clerodanes fromTinnea antiscorbuticaWelv

No evidence of increased chromosomal aberrations and micronuclei in lymphocytes from nonfamilial thyroid cancer patients prior to radiotherapy

scientific article published on 01 November 2000

Normal genetic response to gamma irradiation in familial adenomatous polyposis.

scientific article

Normal red blood cells partially decrease diepoxybutane-induced chromosome breakage in cultured lymphocytes from Fanconi anaemia patients

scientific article published on December 2010

Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria

scientific article (publication date: February 2004)

Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1.

scientific article published in February 2004

On the mechanisms of genotoxicity and metabolism of quercetin

scientific article published on September 1994

Oxidative stress in familial adenomatous polyposis

scientific article published on 01 August 1999

Oxygen species and the genotoxicity of quercetin

scientific article published in January 1992

Polymorphisms in base excision repair genes and thyroid cancer risk.

scientific article

Possible transient adaptive response to mitomycin C in peripheral lymphocytes from thyroid cancer patients after iodine-131 therapy

scientific article published on 01 December 2002

Preferential sensitivity of acrocentric chromosomes to the aneugenic effect of colchicine

scientific article published on 01 January 1996

Prevalence of the Janus kinase 2 V617F mutation in Philadelphia-negative myeloproliferative neoplasms in a Portuguese population

scientific article published on 5 September 2017

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450

scientific article published on 06 December 2018

Prognostic value of microRNA-203a expression in breast cancer.

scientific article published on 5 July 2016

Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide

scientific article

Prototype Systems Containing Human Cytochrome P450 for High-Throughput Real-Time Detection of DNA Damage by Compounds That Form DNA-Reactive Metabolites

scientific article

Quercetin and the mutagenicity of wines

scientific article published in January 1993

Role of haemoglobin in the protection of cultured lymphocytes against diepoxybutane (DEB), assessed by in vitro induced chromosome breakage

scientific article published in April 2003

SNPs/pools: a methodology for the identification of relevant SNPs in breast cancer epidemiology

scientific article published on 24 October 2011

Stereochemical effects in the metabolic activation of nitrosopiperidines: correlations with genotoxicity.

scientific article published in March 2004

Structural requirements for mutagenicity of flavonoids upon nitrosation. A structure-activity study

scientific article published in July 1995

Styrene-oxide N-terminal valine haemoglobin adducts as biomarkers of occupational exposure to styrene

scientific article published on 15 June 2007

Styrene-oxide N-terminal valine haemoglobin adducts in reinforced plastic workers: possible influence of genetic polymorphism of drug-metabolising enzymes

scientific article published on 05 May 2007

Telomerase and reactive oxygen species: Comments on Saretzki, G., 2009. Telomerase, mitochondria and oxidative stress. Exp. Gerontol. 44, 485-492.

scientific article

Ten years' experience with trophoblastic tumors in Portugal.

scientific article published in January 1984

The Na+ -coupled glucose transporter SGLT2 interacts with its accessory unit MAP17 in vitro and their expressions overlap in the renal proximal tubule

scientific article published on 08 September 2018

The Role of Caspase Genes Polymorphisms in Genetic Susceptibility to Philadelphia-Negative Myeloproliferative Neoplasms in a Portuguese Population.

scientific article

The allograft valve in heart transplantation and valve replacement. Genetic assessment of the origin of the cells by means of deoxyribonucleic acid profiles

scientific article published on 01 February 1995

The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms in individual susceptibility to well-differentiated thyroid cancer

scientific article

The role of ERCC2 polymorphisms in breast cancer risk

scientific article published on 01 October 2006

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.

scientific article published in September 2009

The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk.

scientific article published on October 2010

The role of foetal red blood cells in protecting cultured lymphocytes against diepoxybutane-induced chromosome breaks.

scientific article published on 27 December 2005

The role of poly(ADP-ribose)polymerase in the induction of sister chromatid exchanges and micronuclei by mitomycin C in Down's syndrome cells as compared to euploid cells

scientific article published on 01 July 1997

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.

scientific article

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20,

scientific article published on 08 December 2006

Three new labdanes isolated from Eragrostis viscosa

Thyroid Cancer: The Quest for Genetic Susceptibility Involving DNA Repair Genes

scientific article published on 01 August 2019

Transplacental exposure to genotoxins. Evaluation in haemoglobin of hydroxyethylvaline adduct levels in smoking and non-smoking mothers and their newborns.

scientific article

Unusual adult-onset manifestation of an attenuated Bartter's syndrome type IV renal phenotype caused by a mutation in BSND

scientific article published on 25 August 2006

Urinary mutagenicity in occupational exposure to mineral oils and iron oxide particles

scientific article published in January 1982

Use of cytogenetic indicators in radiobiology.

scientific article

VLDL-associated mutagenic activity

scientific article published on April 1982

Wortmannin enhances the induction of micronuclei by low and high LET radiation

scientific article published in March 2003

Wortmannin enhances the induction of micronuclei by low and high LET radiation.

scientific article published on January 2003

mRNA therapy at the convergence of genetics and nanomedicine

scientific article published on 17 March 2023

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