List of works - Rodrigo Franco

A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

scientific article published in 2023

A Naturally Derived Watercress Flower-Based Phenethyl Isothiocyanate-Enriched Extract Induces the Activation of Intrinsic Apoptosis via Subcellular Ultrastructural and Ca2+ Efflux Alterations in an In Vitro Model of Human Malignant Melanoma

scientific article published in 2023

A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma

scientific article published on 31 December 2016

Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells.

scientific article published on 5 June 2016

Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma

scientific article published on 14 February 2019

Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicity

scientific article

Antioxidant gene therapy against neuronal cell death

scientific article published on 12 December 2013

Apoptosis and glutathione: beyond an antioxidant.

scientific article published on 07 August 2009

Association of Autophagy in the Cell Death Mediated by Dihydrotestosterone in Autoreactive T Cells Independent of Antigenic Stimulation

scientific article

Autocrine signaling involved in cell volume regulation: the role of released transmitters and plasma membrane receptors.

scientific article published on July 2008

Combining DI-ESI-MS and NMR datasets for metabolic profiling

scientific article

Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: distinct roles of superoxide anion and superoxide dismutases

scientific article published on 19 April 2013

DNA damage and autophagy

scientific article

DNA damage induced by endogenous aldehydes: current state of knowledge

scientific article published on 16 March 2011

Depolarization, exocytosis and amino acid release evoked by hyposmolarity from cortical synaptosomes

scientific article published in February 2004

Differential modulation of human GABA-ρ1 receptor by sulfur-containing compounds structurally related to taurine

scientific article published on 03 August 2018

Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapies

scientific article published on 26 March 2016

Efflux of osmolyte amino acids during isovolumic regulation in hippocampal slices

scientific article published on 01 September 2000

Environmental toxicity, oxidative stress and apoptosis: ménage à trois.

scientific article published on 09 December 2008

Epidermal growth factor receptor is activated by hyposmolarity and is an early signal modulating osmolyte efflux pathways in Swiss 3T3 fibroblasts

scientific article published on 16 January 2004

Epigenetic therapy as a novel approach in hepatocellular carcinoma.

scientific article published on 07 September 2014

From chemo-prevention to epigenetic regulation: The role of isothiocyanates in skin cancer prevention

scientific article published on 08 June 2018

Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (α-Synuclein)-Environment (Paraquat) Interactions.

scientific article published on 20 June 2016

Glutaredoxin 1 protects dopaminergic cells by increased protein glutathionylation in experimental Parkinson's disease

scientific article

Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis

scientific article

Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation

scientific article

Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.

scientific article published on January 2014

Glutathione efflux and cell death

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Heterogeneous nuclear ribonucleoprotein K supports vesicular stomatitis virus replication by regulating cell survival and cellular gene expression

scientific article published on 10 July 2013

Human aldehyde dehydrogenase 3A1 (ALDH3A1) exhibits chaperone-like function

scientific article

Hyperthermia induces therapeutic effectiveness and potentiates adjuvant therapy with non-targeted and targeted drugs in an in vitro model of human malignant melanoma.

scientific article published on 16 July 2018

Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity

scientific article published on 31 August 2013

Influence of protein tyrosine kinases on cell volume change-induced taurine release

scientific article

Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways

scientific article published on 26 September 2015

Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function

scientific article published on 17 February 2018

Mechanical stretch exacerbates the cell death in SH-SY5Y cells exposed to paraquat: mitochondrial dysfunction and oxidative stress

scientific article published on 21 January 2014

Mechanisms counteracting swelling in brain cells during hyponatremia

scientific article

Mechanisms of the ATP potentiation of hyposmotic taurine release in Swiss 3T3 fibroblasts

scientific article published on 19 August 2004

Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.

scientific article published on 21 March 2017

Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson's Disease

scientific article

Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability

scientific article

Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival

scientific article published on 24 June 2017

Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease

scientific article

Neurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress

scientific article published on 28 March 2018

Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer

scientific article published on 11 December 2018

Osmolytes and mechanisms involved in regulatory volume decrease under conditions of sudden or gradual osmolarity decrease

scientific article published on January 2004

Osmosensitive release of neurotransmitter amino acids: relevance and mechanisms

scientific article

Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis.

scientific article

Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways.

scientific article published on 8 December 2014

Oxidative stress, DNA methylation and carcinogenesis.

scientific article published on 26 March 2008

Oxidative stress, redox signaling, and autophagy: cell death versus survival

scientific article

Pleiotrophic effects of natural products in ROS-induced carcinogenesis: the role of plant-derived natural products in oral cancer chemoprevention.

scientific article published on 28 February 2012

Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis.

scientific article

Reactive oxygen species (ROS)--induced genetic and epigenetic alterations in human carcinogenesis.

scientific article published on 16 March 2011

Redox Biology in Neurological Function, Dysfunction, and Aging.

scientific article published on 14 March 2018

SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis.

scientific article

Sulfur-containing compounds in protecting against oxidant-mediated lung diseases

scientific article published on January 2007

Survival Mechanisms and Xenobiotic Susceptibility of Keratinocytes Exposed to Metal-Derived Nanoparticles

scientific article published on 30 January 2020

The Role of Isothiocyanates as Cancer Chemo-Preventive, Chemo-Therapeutic and Anti-Melanoma Agents.

scientific article

The central role of glutathione in the pathophysiology of human diseases

scientific article

The role of epigenetics in environmental and occupational carcinogenesis.

scientific article published on July 2010

The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development

scientific article published on 15 July 2010

Thiol-redox signaling, dopaminergic cell death, and Parkinson's disease

scientific article

Volume changes and whole cell membrane currents activated during gradual osmolarity decrease in C6 glioma cells: contribution of two types of K+ channels.

scientific article published on 21 January 2004

mTOR/AMPK signaling in the brain: Cell metabolism, proteostasis and survival

scientific article published on 01 April 2018

List of works by Rodrigo Franco

A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

A Naturally Derived Watercress Flower-Based Phenethyl Isothiocyanate-Enriched Extract Induces the Activation of Intrinsic Apoptosis via Subcellular Ultrastructural and Ca2+ Efflux Alterations in an In Vitro Model of Human Malignant Melanoma

A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma

Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells.

Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma

Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicity

Antioxidant gene therapy against neuronal cell death

Apoptosis and glutathione: beyond an antioxidant.

Association of Autophagy in the Cell Death Mediated by Dihydrotestosterone in Autoreactive T Cells Independent of Antigenic Stimulation

Autocrine signaling involved in cell volume regulation: the role of released transmitters and plasma membrane receptors.

Combining DI-ESI-MS and NMR datasets for metabolic profiling

Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: distinct roles of superoxide anion and superoxide dismutases

DNA damage and autophagy

DNA damage induced by endogenous aldehydes: current state of knowledge

Depolarization, exocytosis and amino acid release evoked by hyposmolarity from cortical synaptosomes

Differential modulation of human GABA-ρ1 receptor by sulfur-containing compounds structurally related to taurine

Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapies

Efflux of osmolyte amino acids during isovolumic regulation in hippocampal slices

Environmental toxicity, oxidative stress and apoptosis: ménage à trois.

Epidermal growth factor receptor is activated by hyposmolarity and is an early signal modulating osmolyte efflux pathways in Swiss 3T3 fibroblasts

Epigenetic therapy as a novel approach in hepatocellular carcinoma.

From chemo-prevention to epigenetic regulation: The role of isothiocyanates in skin cancer prevention

Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (α-Synuclein)-Environment (Paraquat) Interactions.

Glutaredoxin 1 protects dopaminergic cells by increased protein glutathionylation in experimental Parkinson's disease

Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis

Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation

Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.

Glutathione efflux and cell death

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Heterogeneous nuclear ribonucleoprotein K supports vesicular stomatitis virus replication by regulating cell survival and cellular gene expression

Human aldehyde dehydrogenase 3A1 (ALDH3A1) exhibits chaperone-like function

Hyperthermia induces therapeutic effectiveness and potentiates adjuvant therapy with non-targeted and targeted drugs in an in vitro model of human malignant melanoma.

Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity

Influence of protein tyrosine kinases on cell volume change-induced taurine release

Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways

Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function

Mechanical stretch exacerbates the cell death in SH-SY5Y cells exposed to paraquat: mitochondrial dysfunction and oxidative stress

Mechanisms counteracting swelling in brain cells during hyponatremia

Mechanisms of the ATP potentiation of hyposmotic taurine release in Swiss 3T3 fibroblasts

Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.

Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson's Disease

Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability

Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival

Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease

Neurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress

Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer

Osmolytes and mechanisms involved in regulatory volume decrease under conditions of sudden or gradual osmolarity decrease

Osmosensitive release of neurotransmitter amino acids: relevance and mechanisms

Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis.

Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways.

Oxidative stress, DNA methylation and carcinogenesis.

Oxidative stress, redox signaling, and autophagy: cell death versus survival

Pleiotrophic effects of natural products in ROS-induced carcinogenesis: the role of plant-derived natural products in oral cancer chemoprevention.

Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis.

Reactive oxygen species (ROS)--induced genetic and epigenetic alterations in human carcinogenesis.

Redox Biology in Neurological Function, Dysfunction, and Aging.

SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis.

Sulfur-containing compounds in protecting against oxidant-mediated lung diseases

Survival Mechanisms and Xenobiotic Susceptibility of Keratinocytes Exposed to Metal-Derived Nanoparticles

The Role of Isothiocyanates as Cancer Chemo-Preventive, Chemo-Therapeutic and Anti-Melanoma Agents.

The central role of glutathione in the pathophysiology of human diseases

The role of epigenetics in environmental and occupational carcinogenesis.

The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development

Thiol-redox signaling, dopaminergic cell death, and Parkinson's disease

Volume changes and whole cell membrane currents activated during gradual osmolarity decrease in C6 glioma cells: contribution of two types of K+ channels.

mTOR/AMPK signaling in the brain: Cell metabolism, proteostasis and survival