List of works by Chwee Teck Lim

3D coupling of fibronectin fibril arrangement with topology of ventral plasma membrane.

scientific article published on 12 March 2012

A 3D microvascular network model to study the impact of hypoxia on the extravasation potential of breast cell lines

scientific article published in Scientific Reports

A Basis for Rapid Clearance of Circulating Ring-Stage Malaria Parasites by the Spiroindolone KAE609.

scientific article

A Biofunctional Fibrous Scaffold for the Encapsulation of Human Mesenchymal Stem Cells and its Effects on Stem Cell Differentiation

A comparative molecular force spectroscopy study of homophilic JAM-A interactions and JAM-A interactions with reovirus attachment protein sigma1.

scientific article published on July 2008

A microfluidics approach towards high-throughput pathogen removal from blood using margination

scientific article

A power-law rheology-based finite element model for single cell deformation

scientific article published on 4 February 2012

AFM indentation study of breast cancer cells

scientific article

Actin flow and talin dynamics govern rigidity sensing in actin-integrin linkage through talin extension

scientific article

Actomyosin bundles serve as a tension sensor and a platform for ERK activation.

scientific article

Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing

scientific article

Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion

scientific article published on 15 January 2021

Advances in microfluidics in combating infectious diseases

scientific article published on 5 February 2016

Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing

scientific article published on 03 November 2021

All-Optical Chirality-Sensitive Sorting via Reversible Lateral Forces in Interference Fields.

scientific article published on 2 April 2017

An ultra-high-throughput spiral microfluidic biochip for the enrichment of circulating tumor cells

scientific article published on July 2014

Artificial hagfish protein fibers with ultra-high and tunable stiffness

scientific article

Atomic force microscope imaging of chromatin assembled in Xenopus laevis egg extract

scientific article

Atomic force microscopy study of the antimicrobial action of Sushi peptides on Gram negative bacteria

scientific article published on 21 December 2006

Biological Tissues as Active Nematic Liquid Crystals

scientific article published on 29 August 2018

Biophysical Methods to Probe Claudin-Mediated Adhesion at the Cellular and Molecular Level

Biophysical properties of human breast cancer cells measured using silicon MEMS resonators and atomic force microscopy

scientific article published in February 2015

Biophysics of malarial parasite exit from infected erythrocytes

scientific article

Bone marrow regeneration promoted by biophysically sorted osteoprogenitors from mesenchymal stromal cells.

scientific article

Cationic polyrotaxanes as gene carriers: physicochemical properties and real-time observation of DNA complexation, and gene transfection in cancer cells.

scientific article

Celebrating Soft Matter's 10th Anniversary: Cell division: a source of active stress in cellular monolayers. ⬇️

scientific article published on 12 August 2015

Cell adhesion properties on photochemically functionalized diamond

scientific article published on 04 April 2007

Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate

scientific article published on 16 February 2016

Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress

scientific article published on 22 May 2020

Characterization of bulk properties of nanofibrous scaffolds from nanomechanical properties of single nanofibers

scientific article published in June 2006

Characterization of the surface biocompatibility of the electrospun PCL-collagen nanofibers using fibroblasts

scientific article published in September 2005

Chitosan nanofibers from an easily electrospinnable UHMWPEO-doped chitosan solution system

scientific article published on 14 December 2007

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

scientific article published on 15 November 2010

Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumor cells

scientific article

Coaxial electrospinning of (fluorescein isothiocyanate-conjugated bovine serum albumin)-encapsulated poly(epsilon-caprolactone) nanofibers for sustained release.

scientific article

Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells.

scientific article

Collective cell migration: a mechanistic perspective

scientific article

Compendiums of cancer transcriptomes for machine learning applications

scientific article published on 08 October 2019

Computational model of cell positioning: directed and collective migration in the intestinal crypt epithelium.

scientific article

Concentric gel system to study the biophysical role of matrix microenvironment on 3D cell migration.

scientific article

Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria.

scientific article

Controlled biomineralization of electrospun poly(ε-caprolactone) fibers to enhance their mechanical properties

scientific article

Correction: Molecular Mechanistic Insights into the Endothelial Receptor Mediated Cytoadherence of -Infected Erythrocytes

Corrigendum: Force-dependent conformational switch of α-catenin controls vinculin binding

scientific article published on 04 March 2015

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

scientific article

Defect engineered bioactive transition metals dichalcogenides quantum dots

scientific article published in Nature Communications

Deformability based cell margination--a simple microfluidic design for malaria-infected erythrocyte separation.

scientific article published on 5 August 2010

Deformability study of breast cancer cells using microfluidics

scientific article

Detection of Clinical Mesenchymal Cancer Cells from Bladder Wash Urine for Real-Time Detection and Prognosis

scientific article published on 30 August 2019

Detection of Lung Cancer: Concomitant Volatile Organic Compounds and Metabolomic Profiling of Six Cancer Cell Lines of Different Histological Origins

scientific article published on 10 May 2018

Differential Depth Sensing Reduces Cancer Cell Proliferation via Rho-Rac-Regulated Invadopodia

scientific article published on 27 June 2017

Directing Assembly and Disassembly of 2D MoS2 Nanosheets with DNA for Drug Delivery.

scientific article

Drop Impact Reliability ¿ A Comprehensive Summary

Dual-Core Capacitive Microfiber Sensor for Smart Textile Applications

scientific article published on 27 August 2019

Effect of fibrin glue on the biomechanical properties of human Descemet's membrane

scientific article

Effect of hydrogen peroxide on intertubular dentine

scientific article published on 10 December 2004

Effect of molecular orientation on mechanical property of single electrospun fiber of poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate].

scientific article published in October 2009

Effect of plasmodial RESA protein on deformability of human red blood cells harboring Plasmodium falciparum.

scholarly article

Effect of ultrasound on cyprid footprint and juvenile barnacle adhesion on a fouling release material.

scientific article published on 23 November 2013

Effects of annealing on the structural and mechanical properties of electrospun polymeric nanofibres

scientific article published on 5 May 2006

Effects of magnesium salt concentrations on B-DNA overstretching transition.

scientific article published in May 2009

Electrochemically Induced Amorphization and Unique Lithium and Sodium Storage Pathways in FeSbO4 Nanocrystals

scientific article published on 24 May 2019

Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds.

scientific article

Electrospun biomimetic nanocomposite nanofibers of hydroxyapatite/chitosan for bone tissue engineering

scientific article

Emergence of microfluidic wearable technologies

scientific article published on 28 September 2016

Enhanced biomineralization in osteoblasts on a novel electrospun biocomposite nanofibrous substrate of hydroxyapatite/collagen/chitosan

scientific article

Enhancing the sensing specificity of a MoS2 nanosheet-based FRET aptasensor using a surface blocking strategy

scientific article published in June 2017

EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization

scientific article published on 13 April 2021

Epithelial Cell Packing Induces Distinct Modes of Cell Extrusions

scientific article

Epithelial bridges maintain tissue integrity during collective cell migration.

scientific article published on December 2013

Estradiol influences the mechanical properties of human fetal osteoblasts through cytoskeletal changes

scientific article

Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges

scientific article

Expression dynamics and physiologically relevant functional study of STEVOR in asexual stages of Plasmodium falciparum infection

scientific article

Fabrication of large pores in electrospun nanofibrous scaffolds for cellular infiltration: a review.

scientific article published on 14 December 2011

Failure Mechanisms of Interconnections in Drop Impact

Flexible Hybrid Sensors for Health Monitoring: Materials and Mechanisms to Render Wearability

scientific article published on 24 July 2019

Flexural strength of dental composite restoratives: comparison of biaxial and three-point bending test

scientific article published on 01 November 2004

Flow sensing of single cell by graphene transistor in a microfluidic channel

scientific article published on 18 November 2011

Fluorinated graphene for promoting neuro-induction of stem cells

scientific article published on 12 June 2012

Force-dependent conformational switch of α-catenin controls vinculin binding

scientific article published in Nature Communications

Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

scientific article published on 22 January 2014

From qualitative data to correlation using deep generative networks: Demonstrating the relation of nuclear position with the arrangement of actin filaments

scientific article published in 2022

Geometrical constraints and physical crowding direct collective migration of fibroblasts.

scientific article published on March 2013

Graphene oxide inhibits malaria parasite invasion and delays parasitic growth in vitro

scientific article published on 13 September 2017

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

scientific article

High density of 'spiky' excrescences covering the surface of an erythrocyte infected with Plasmodium malariae

scientific article

High-Speed Bend Test Method and Failure Prediction for Drop Impact Reliability

High-performance graphene-titania platform for detection of phosphopeptides in cancer cells

scientific article

High-throughput cell cycle synchronization using inertial forces in spiral microchannels.

scientific article published on 18 February 2011

High-throughput malaria parasite separation using a viscoelastic fluid for ultrasensitive PCR detection

scientific article published on 10 May 2016

High-throughput synchronization of mammalian cell cultures by spiral microfluidics.

scientific article published in January 2014

Highly Flexible Graphene Oxide Nanosuspension Liquid-Based Microfluidic Tactile Sensor.

scientific article published on 2 February 2016

Highly Stretchable, Weavable, and Washable Piezoresistive Microfiber Sensors

scientific article published on 06 April 2018

Highly wrinkled cross-linked graphene oxide membranes for biological and charge-storage applications

scientific article published on 13 December 2011

Homophilic interaction and deformation of E-cadherin and cadherin 7 probed by single molecule force spectroscopy.

scientific article published on 14 October 2015

Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum.

scientific article

Hybrid capillary-inserted microfluidic device for sheathless particle focusing and separation in viscoelastic flow

scientific article

Hydrostatic pressure promotes endothelial tube formation through aquaporin 1 and Ras-ERK signaling

scientific article published on 02 April 2020

Inference of Internal Stress in a Cell Monolayer ⬇️

scientific article published on April 2016

Influence of irrigation regimens on the adherence of Enterococcus faecalis to root canal dentin

scientific article published in July 2008

Intraoperative cell salvage in metastatic spine tumour surgery reduces potential for reinfusion of viable cancer cells

scientific article published on 7 March 2016

Investigations on the Structural Damage in Human Erythrocytes Exposed to Silver, Gold, and Platinum Nanoparticles

scientific article published on 23 April 2010

Jetting microfluidics with size-sorting capability for single-cell protease detection

scientific article

Kinetics of Adhesion Mediated by Extracellular Loops of Claudin-2 as Revealed by Single-Molecule Force Spectroscopy

Large-Area Silver-Stibnite Nanoporous Plasmonic Films for Label-Free Biosensing

scientific article published on 02 October 2018

Life cycle-dependent cytoskeletal modifications in Plasmodium falciparum infected erythrocytes

scientific article

Liquid biopsy for minimal residual disease detection in leukemia using a portable blast cell biochip

scientific article published on 02 December 2019

Liquid biopsy: one cell at a time

scientific article published on 02 October 2019

Low-Dimensional Transition Metal Dichalcogenide Nanostructures Based Sensors

article published in 2016

MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility

scientific article published on 15 August 2016

Malaria detection using inertial microfluidics

scientific article published on February 2015

Manipulation and isolation of single cells and nuclei.

scientific article published on January 2010

Margination of red blood cells infected by Plasmodium falciparum in a microvessel

scientific article published on 21 March 2011

Measurement of Poisson's ratio of dental composite restorative materials

scientific article published in June 2004

Mechanical properties of single electrospun drug-encapsulated nanofibres

scientific article published on August 2006

Mechanics of epithelial closure over non-adherent environments

scientific article

Mechanistic Understanding of the Biological Responses to Polymeric Nanoparticles

scientific article published on 06 April 2020

Mechanistic adaptability of cancer cells strongly affects anti-migratory drug efficacy

scientific article

Mechanobiology

scientific article published on 7 April 2010

Mechanobiology of Tumor Growth

Mechanobiology of cell migration in the context of dynamic two-way cell-matrix interactions

scientific article

Mesenchymal stem cells reduce intervertebral disc fibrosis and facilitate repair

scientific article published on 01 August 2014

Micellization phenomena of biodegradable amphiphilic triblock copolymers consisting of poly(beta-hydroxyalkanoic acid) and poly(ethylene oxide).

scientific article published in September 2005

Micro and nanotechnology for biological and biomedical applications.

scientific article published on 16 September 2010

Microdevice for the isolation and enumeration of cancer cells from blood.

scientific article published in August 2009

Microfluidic cell trap array for controlled positioning of single cells on adhesive micropatterns

scientific article

Microfluidic device for sheathless particle focusing and separation using a viscoelastic fluid.

scientific article published on 19 June 2015

Microfluidic enrichment for the single cell analysis of circulating tumor cells

scientific article

Microfluidic label-free bioprocessing of human reticulocytes from erythroid culture

scientific article published on 14 August 2020

Microfluidic label-free selection of mesenchymal stem cell subpopulation during culture expansion extends the chondrogenic potential in vitro

scientific article published on 20 February 2018

Microfluidic modelling of the tumor microenvironment for anti-cancer drug development

scientific article published on 01 January 2019

Microfluidic size separation of cells and particles using a swinging bucket centrifuge

scientific article

Microfluidic technologies.

scientific article published on January 2012

Microfluidics for cell separation.

scientific article published on 23 April 2010

Microfluidics for research and applications in oncology

scientific article published on 26 May 2015

Modeling cell entry into a micro-channel

scientific article published on 23 November 2010

Modeling the size-dependent elastic properties of polymeric nanofibers

scientific article

Molecular Hemocompatibility of Graphene Oxide and Its Implication for Antithrombotic Applications.

scientific article published on 3 August 2015

Molecular dynamics simulation of ZnO nanowires: size effects, defects, and super ductility.

scientific article published in January 2010

Molecular interactions of graphene oxide with human blood plasma proteins

scientific article published on 20 April 2016

Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion.

scientific article published on 4 March 2013

Molecular mechanisms underlying the force-dependent regulation of actin-to-ECM linkage at the focal adhesions

scientific article published on January 2014

Molecular mechanistic insights into the endothelial receptor mediated cytoadherence of Plasmodium falciparum-infected erythrocytes

scientific article

Multivariate biophysical markers predictive of mesenchymal stromal cell multipotency

scientific article

Mussel inspired protein-mediated surface modification to electrospun fibers and their potential biomedical applications

scientific article published on 24 January 2012

Nanoindentation study of human premolars subjected to bleaching agent

scientific article published in November 2005

Nanomechanical Microfluidic Mixing and Rapid Labeling of Silica Nanoparticles using Allenamide-Thiol Covalent Linkage for Bioimaging

scientific article published on 25 January 2019

Nanomechanics insights into the performance of healthy and osteoporotic bones

scientific article published on 2 October 2013

Nanostructure of collagen fibrils in human nucleus pulposus and its correlation with macroscale tissue mechanics

scientific article published on 01 April 2010

New insights into the altered adhesive and mechanical properties of red blood cells parasitized by Babesia bovis

scientific article published on 19 July 2007

Observations on the internal and surface morphology of malaria infected blood cells using optical and atomic force microscopy

scientific article published on 7 March 2006

Pan-cancer analysis connects tumor matrisome to immune response

scientific article published on 22 May 2019

Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation.

scientific article published on 19 April 2011

Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes

scientific article

Polysaccharide nanofibers with variable compliance for directing cell fate

scientific article published on 4 June 2014

Potassium channel dysfunction in human neuronal models of Angelman syndrome

scientific article published on 01 December 2019

Power-law rheology analysis of cells undergoing micropipette aspiration

scientific article published on 24 February 2010

Probing effects of pH change on dynamic response of Claudin-2 mediated adhesion using single molecule force spectroscopy

article

Probing the cytoadherence of malaria infected red blood cells under flow

scientific article

Prognostic Neurotransmitter Receptors Genes Are Associated with Immune Response, Inflammation and Cancer Hallmarks in Brain Tumors

scientific article published on 21 May 2022

Quantifying Tensile Force and ERK Phosphorylation on Actin Stress Fibers

scientific article published in January 2017

Rapid construction of mechanically- confined multi- cellular structures using dendrimeric intercellular linker.

scientific article published on October 2010

Rapid quantification of live cell receptors using bioluminescence in a flow-based microfluidic device

scientific article published on 21 October 2014

Rapid, high-throughput tracking of bacterial motility in 3D via phase-contrast holographic video microscopy.

scientific article

Rational Design of Materials Interface for Efficient Capture of Circulating Tumor Cells.

scientific article published on 16 July 2015

Regulation of epithelial cell organization by tuning cell-substrate adhesion

scientific article

Relationship between transit time and mechanical properties of a cell through a stenosed microchannel

scientific article published on 8 January 2018

Reprint of: Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria

scientific article

Role of Cytoskeletal Tension in the Induction of Cardiomyogenic Differentiation in Micropatterned Human Mesenchymal Stem Cell

scientific article published on 6 May 2015

Selective Accelerated Proliferation of Malignant Breast Cancer Cells on Planar Graphene Oxide Films.

scientific article published on 26 February 2016

Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes

scientific article (publication date: 2013)

Single cell kinase signaling assay using pinched flow coupled droplet microfluidics.

scientific article

Single cell rigidity sensing: A complex relationship between focal adhesion dynamics and large-scale actin cytoskeleton remodeling

scientific article published on 06 April 2016

Single-Cell Analysis of Circulating Tumor Cells: Why Heterogeneity Matters

scientific article published on 19 October 2019

Single-Layer Ternary Chalcogenide Nanosheet as a Fluorescence-Based "Capture-Release" Biomolecular Nanosensor.

scientific article published on 18 November 2016

Single-Molecular-Level Study of Claudin-1-Mediated Adhesion

article by Tong Seng Lim et al published January 2008 in Langmuir

Single-cell profiling approaches to probing tumor heterogeneity.

scientific article

Size selective assembly of colloidal particles on a template by directed self-assembly technique.

scientific article published in September 2006

Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells

scientific article published on January 2014

Spectrin-level modeling of the cytoskeleton and optical tweezers stretching of the erythrocyte

scientific article

Stiffening of Red Blood Cells Induced by Cytoskeleton Disorders: A Joint Theory-Experiment Study ⬇️

scientific article

Stretching and relaxation of malaria-infected red blood cells

scientific article published on September 2013

Structure-mechanical property of individual cobalt oxide nanowires

scientific article published on 30 August 2008

Substrate topography determines the fate of chondrogenesis from human mesenchymal stem cells resulting in specific cartilage phenotype formation.

scientific article published on 22 April 2014

Substrate-friendly synthesis of metal oxide nanostructures using a hotplate

scientific article published on 01 January 2006

Synthesis of "cactus" top-decorated aligned carbon nanotubes and their third-order nonlinear optical properties.

scientific article published in April 2006

Tensile testing of a single ultrafine polymeric fiber.

scientific article published in May 2005

The malaria parasite progressively dismantles the host erythrocyte cytoskeleton for efficient egress

scientific article

Thermal treatments modulate bacterial adhesion to dental enamel

scientific article

Thickness sensing of hMSCs on collagen gel directs stem cell fate.

scientific article published on 17 September 2010

Topography induces differential sensitivity on cancer cell proliferation via Rho-ROCK-Myosin contractility

scientific article published on 22 January 2016

Topological defects in epithelia govern cell death and extrusion

scientific article published on April 2017

Toxicity of Two-Dimensional Layered Materials and Their Heterostructures

scientific article published on 19 August 2019

Tumor dissemination: an EMT affair

scientific article published on 01 March 2013

Two-stage sample-to-answer system based on nucleic acid amplification approach for detection of malaria parasites

scientific article published on 22 March 2016

Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics

scientific article published on 17 December 2015

Uncovering mechanosensing mechanisms at the single protein level using magnetic tweezers.

scientific article published on 26 August 2015

Use of atomic force microscopy as a tool to understand the action of antimicrobial peptides on bacteria

scientific article

Versatile transfer of aligned carbon nanotubes with polydimethylsiloxane as the intermediate.

scientific article published on 2 July 2008

Wearable tactile sensor based on flexible microfluidics

scientific article published on 20 July 2016

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