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List of works by Bernd Reif

1H detected 1H,15N correlation spectroscopy in rotating solids

1H detection in MAS solid-state NMR spectroscopy of biomacromolecules employing pulsed field gradients for residual solvent suppression

scientific article

1H-1H MAS correlation spectroscopy and distance measurements in a deuterated peptide.

scientific article published in August 2001

A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly

scientific article published on 4 September 2015

A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions.

scientific article published on 29 January 2016

A residue-specific shift in stability and amyloidogenicity of antibody variable domains

scientific article published on 5 August 2014

Access to Cα backbone dynamics of biological solids by 13C T1 relaxation and molecular dynamics simulation

scientific article published on 15 January 2015

Accurate Determination of 1 H-15 N Dipolar Couplings Using Inaccurate Settings of the Magic Angle in Solid-State NMR Spectroscopy

scientific article published on 27 February 2019

Accurate determination of order parameters from 1H,15N dipolar couplings in MAS solid-state NMR experiments

scientific article

Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization

scientific article

An asymmetric dimer as the basic subunit in Alzheimer's disease amyloid β fibrils.

scientific article published on 8 May 2012

Assignment of dynamic regions in biological solids enabled by spin-state selective NMR experiments

scientific article published in July 2010

Assignment strategies for aliphatic protons in the solid-state in randomly protonated proteins ⬇️

scientific article published on December 4, 2011

Bacterial inclusion bodies of Alzheimer's disease β-amyloid peptides can be employed to study native-like aggregation intermediate states

scientific article published on 10 January 2011

Characterization of (1)H-(1)H distances in a uniformly (2)H,(15)N-labeled SH3 domain by MAS solid-state NMR spectroscopy (section sign).

scientific article

Characterization of Dynamics of Perdeuterated Proteins by MAS Solid-State NMR

article

Characterization of chemical exchange between soluble and aggregated states of beta-amyloid by solution-state NMR upon variation of salt conditions

scientific article

Characterization of dynamic processes using deuterium in uniformly 2H,13C,15N enriched peptides by MAS solid-state NMR.

scientific article

Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.

scientific article

Cloning, expression and purification of the human Islet Amyloid Polypeptide (hIAPP) from Escherichia coli

scientific article published on 6 November 2014

Combined analysis of (15)N relaxation data from solid- and solution-state NMR spectroscopy

scientific article

Comparative Study of REDOR and CPPI Derived Order Parameters by 1H-Detected MAS NMR and MD Simulations

scientific article published on 25 August 2017

Comparison of solid-state dipolar couplings and solution relaxation data provides insight into protein backbone dynamics

scientific article

Cross-Correlated Relaxation for the Measurement of Angles between Tensorial Interactions

Cross-correlated relaxation for measurement of angles between tensorial interactions.

scientific article

Cryogenic solid state NMR studies of fibrils of the Alzheimer's disease amyloid-β peptide: perspectives for DNP.

scientific article published on 22 June 2013

De novo determination of peptide structure with solid-state magic-angle spinning NMR spectroscopy.

scientific article

Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.

scientific article

Determination of multiple torsion-angle constraints in U-(13)C,(15)N-labeled peptides: 3D (1)H-(15)N-(13)C-(1)H dipolar chemical shift NMR spectroscopy in rotating solids

article

Deuterated Peptides and Proteins: Structure and Dynamics Studies by MAS Solid-State NMR ⬇️

scientific article published on January 1, 2012

Deuterated peptides and proteins in MAS solid-state NMR

Differential line broadening in MAS solid-state NMR due to dynamic interference

scientific article published on 31 July 2007

Differentiation of HMBC two- and three-bond correlations: A method to simplify the structure determination of natural products

article

Dimer formation of a stabilized Gbeta1 variant: a structural and energetic analysis

scientific article

Direct measurement of angles between bond vectors in high-resolution NMR.

scientific article published in May 1997

Direct observation of millisecond to second motions in proteins by dipolar CODEX NMR spectroscopy

scientific article

Dynamics in the solid-state: perspectives for the investigation of amyloid aggregates, membrane proteins and soluble protein complexes

article

Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice

scientific article

Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains

scientific article published on 27 January 2017

Experimental Determination of Microsecond Reorientation Correlation Times in Protein Solutions

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein

scientific article

High Resolution1H Detected1H,13C Correlation Spectra in MAS Solid-State NMR using Deuterated Proteins with Selective1H,2H Isotopic Labeling of Methyl Groups

scientific article published in 2006

High resolution 1H-detected solid-state NMR spectroscopy of protein aliphatic resonances: access to tertiary structure information

scientific article

High-resolution double-quantum deuterium magic angle spinning solid-state NMR spectroscopy of perdeuterated proteins

scientific article published in 2009

Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP.

scientific article published on 8 January 2008

Hydrogen bonding involving side chain exchangeable groups stabilizes amyloid quarternary structure

scientific article published in August 2013

Identification of Hydroxyl Protons, Determination of Their Exchange Dynamics, and Characterization of Hydrogen Bonding in a Microcrystallin Protein

article

Immobilization of soluble protein complexes in MAS solid-state NMR: Sedimentation versus viscosity

scientific article

Importance of low-oligomeric-weight species for prion propagation in the yeast prion system Sup35/Hsp104.

scientific article

In support of the BMRB.

scientific article published in September 2012

Internal protein dynamics on ps to μs timescales as studied by multi-frequency (15)N solid-state NMR relaxation

scientific article published on 19 September 2013

Large protein complexes with extreme rotational correlation times investigated in solution by magic-angle-spinning NMR spectroscopy

scientific article published in November 2009

Limits of Resolution and Sensitivity of Proton Detected MAS Solid-State NMR Experiments at 111 kHz in Deuterated and Protonated Proteins

scientific article

Local Structure and Relaxation in Solid-State NMR: Accurate Measurement of Amide N−H Bond Lengths and H−N−H Bond Angles

scientific article published in 2000

MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors

scientific article published on 26 July 2017

MAS solid-state NMR studies on the multidrug transporter EmrE.

scientific article published on 2 October 2007

Measurement of 15N-T1 relaxation rates in a perdeuterated protein by magic angle spinning solid-state nuclear magnetic resonance spectroscopy

scientific article published in February 2008

Measurement of 2J(H,C)- and 3J(H,C)-coupling constants by alpha/beta selective HC(C)H-TOCSY.

scientific article published in October 2001

Measurements of residual dipolar couplings in peptide inhibitors weakly aligned by transient binding to peptide amyloid fibrils

scientific article published in August 2004

Methyl rotation barriers in proteins from 2H relaxation data. Implications for protein structure

scientific article

Microsecond time scale mobility in a solid protein as studied by the 15N R(1rho) site-specific NMR relaxation rates

scientific article

NH-NH vector correlation in peptides by solid-state NMR

scientific article published on 01 July 2000

NMR Spectroscopic Determination of Angles α and ζ in RNA from CH-Dipolar Coupling, P-CSA Cross-Correlated Relaxation

article published in 2000

NMR assignments of the periplasmic loop P2 of the MalF subunit of the maltose ATP binding cassette transporter.

scientific article published on 16 November 2008

NMR evidence for helix geometry modifications by a G-U wobble base pair in the acceptor arm of E. coli tRNAAla

article

NMR spectroscopy of soluble protein complexes at one mega-dalton and beyond

scientific article

Narrow carbonyl resonances in proton-diluted proteins facilitate NMR assignments in the solid-state

scientific article published on 16 March 2010

Optimal (2)H rf Pulses and (2)H-(13)C Cross-Polarization Methods for Solid-State (2)H MAS NMR of Perdeuterated Proteins

scientific article published on 12 May 2011

Optimal degree of protonation for ¹H detection of aliphatic sites in randomly deuterated proteins as a function of the MAS frequency

scientific article

Optimum levels of exchangeable protons in perdeuterated proteins for proton detection in MAS solid-state NMR spectroscopy

scientific article

Periplasmic loop P2 of the MalF subunit of the maltose ATP binding cassette transporter is sufficient to bind the maltose binding protein MalE.

scientific article

Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization

scientific article

Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble

scientific article published on 18 November 2021

Probing surface accessibility of proteins using paramagnetic relaxation in solid-state NMR spectroscopy

scientific article

Protein side-chain dynamics as observed by solution- and solid-state NMR spectroscopy: a similarity revealed

scientific article

Protein side-chain dynamics observed by solution- and solid-state NMR: comparative analysis of methyl 2H relaxation data

scientific article

Protein-RNA interfaces probed by 1H-detected MAS solid-state NMR spectroscopy

scientific article published on 18 January 2013

Proton-detected scalar coupling based assignment strategies in MAS solid-state NMR spectroscopy applied to perdeuterated proteins

scientific article

Proton-detected solid-state NMR spectroscopy at aliphatic sites: application to crystalline systems

scientific article published on 07 June 2013

Proton-detected solid-state NMR spectroscopy of fibrillar and membrane proteins.

scientific article published on 14 April 2011

Quantification of protein backbone hydrogen-deuterium exchange rates by solid state NMR spectroscopy

scientific article

Quantitative analysis of backbone motion in proteins using MAS solid-state NMR spectroscopy

scientific article

Quantitative measurement of differential 15N-H(alpha/beta)T2 relaxation rates in a perdeuterated protein by MAS solid-state NMR spectroscopy.

scientific article

Radiofrequency fields in MAS solid state NMR probes

scientific article

Residual methyl protonation in perdeuterated proteins for multi-dimensional correlation experiments in MAS solid-state NMR spectroscopy

scientific article

Resolution enhancement in MAS solid-state NMR by application of 13C homonuclear scalar decoupling during acquisition

scientific article published in January 2005

Restoring Resolution in Biological Solid-State NMR under Conditions of Off-Magic-Angle Spinning

Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability

scientific article published on 22 October 2020

Sensitivity enhancement using paramagnetic relaxation in MAS solid-state NMR of perdeuterated proteins

scientific article published on 18 September 2007

Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case

scientific article

Site-specific analysis of heteronuclear Overhauser effects in microcrystalline proteins

Site-specific solid-state NMR studies of "trigger factor" in complex with the large ribosomal subunit 50S.

scientific article published on 5 February 2015

Slow motions in microcrystalline proteins as observed by MAS-dependent 15N rotating-frame NMR relaxation

scientific article published on 20 September 2014

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes

scientific journal article

Small molecule induced toxic human-IAPP species characterized by NMR

scientific article published on 02 October 2020

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils

scientific article

Solid state NMR assignments of a human λ-III immunoglobulin light chain amyloid fibril

scientific article published on 18 September 2020

Solid- and solution-state nuclear magnetic resonance spectroscopic studies on antibody light chain amyloid formation and interactions with epigallocatechin gallate

Solid-state NMR of proteins sedimented by ultracentrifugation

scientific article

Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate

scientific article

Structural Comparison of Oligoribonucleotides and Their 2′-Deoxy-2′-fluoro Analogs by heteronuclear NMR spectroscopy

scholarly article by Bernd Reif et al published 22 September 1997 in Helvetica Chimica Acta

Structural Insight into IAPP-Derived Amyloid Inhibitors and Their Mechanism of Action

scientific article published on 28 January 2020

Structural Mechanism of the Interaction of Alzheimer Disease Aβ Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac Sulfide

scientific article

Structural and mechanistic implications of metal binding in the small heat-shock protein αB-crystallin

scientific article published on 15 November 2011

Structural properties of EGCG-induced, nontoxic Alzheimer's disease Aβ oligomers.

scientific article published on 28 January 2012

Structure and orientation of peptide inhibitors bound to beta-amyloid fibrils

scientific article published on 5 October 2005

Structure calculation from unambiguous long-range amide and methyl 1H-1H distance restraints for a microcrystalline protein with MAS solid-state NMR spectroscopy

scientific article

Substrate transport activation is mediated through second periplasmic loop of transmembrane protein MalF in maltose transport complex of Escherichia coli ⬇️

scientific article

Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-β Peptide Which Exhibit Reduced Neurotoxicity

scientific article published on 22 February 2016

TROSY effects in MAS solid-state NMR

article

The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation

scientific article

The Conformation ofcyclo(−d-Pro−Ala4−) as a Model for Cyclic Pentapeptides of thedL4Type

article

The amyloid precursor protein and its homologues: structural and functional aspects of native and pathogenic oligomerization

scientific article

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client

scientific article published on 12 October 2015

The mechanism of denaturation and the unfolded state of the α-helical membrane-associated protein Mistic.

scientific article

The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation.

scientific article

The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes

scientific article published on 13 March 2017

The structure and oxidation of the eye lens chaperone αA-crystallin

scientific article published on 02 December 2019

Three-dimensional deuterium-carbon correlation experiments for high-resolution solid-state MAS NMR spectroscopy of large proteins.

scientific article

Ultra-high resolution in MAS solid-state NMR of perdeuterated proteins: Implications for structure and dynamics ⬇️

scientific article published on 05 January 2012

Ultrahigh resolution in proton solid-state NMR spectroscopy at high levels of deuteration

scientific article published in June 2006

Yeast prion-protein, sup35, fibril formation proceeds by addition and substraction of oligomers

scientific article published in May 2006

alphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35

scientific article

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