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List of works by Michael D Rainey

A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response

scientific article (publication date: 2014)

Analysing the DNA damage and replication checkpoints in DT40 cells.

scientific article published on January 2006

CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage

scientific article published on 04 June 2020

Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint

scientific article published on 17 April 2013

Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage

scientific article

Characterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular Models

scientific article published on 24 July 2013

Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

scientific article

Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.

scientific article

Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.

scientific article published on 6 August 2007

DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach

scientific article (publication date: 14 October 2016)

DNA Replication Dynamics and Cellular Responses to ATP Competitive CDC7 Kinase Inhibitors

scientific article published on 31 May 2017

DNA mediated chromatin pull-down for the study of chromatin replication.

scientific article published on 19 September 2011

Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation

scientific article

Lethal errors in checkpoint control--life without Chk1.

scientific article

Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint

scientific article published on 18 December 2015

The Deubiquitinase USP9X Maintains DNA Replication Fork Stability and DNA Damage Checkpoint Responses by Regulating CLASPIN during S-Phase.

scientific article published on 26 February 2016

The yeast CDC9 gene encodes both a nuclear and a mitochondrial form of DNA ligase I.

scientific article

Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation

scientific article

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