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List of works by Edward Parkin

A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.

scientific article

A point mutation in the juxtamembrane stalk of human angiotensin I-converting enzyme invokes the action of a distinct secretase

scientific article published on 23 March 2001

A role for calcium and annexins in the formation of caveolae

scientific article published in August 1996

ADAMs family members as amyloid precursor protein alpha-secretases

scientific article published on November 2003

Angiotensin-converting enzyme as a GPIase: a critical reevaluation

scientific article published in November 2005

Cell proliferation and CTP:cholinephosphate cytidylyltransferase activity in higher plants ⬇️

scientific article published on 01 August 1998

Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein

scientific article published on 15 June 2007

Characterization of detergent-insoluble complexes containing the familial Alzheimer's disease-associated presenilins

scientific article published in April 1999

Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signaling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells

scientific article published on 30 August 2012

Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins ⬇️

scientific article published on August 1, 1998

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

scientific article published on April 2010

Dual mechanisms for shedding of the cellular prion protein

scientific article published on 7 January 2004

Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event.

scientific article published in December 2010

Herpes simplex virus interferes with amyloid precursor protein processing

scientific article

Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes

scientific article published on November 1996

Membrane raft actin deficiency and altered Ca2+-induced vesiculation in stomatin-deficient overhydrated hereditary stomatocytosis

scientific article

Modulation of phosphatidylcholine biosynthesis in celery by exogenous fatty acids

scientific article published on 01 January 1999

Osteonectin as a screening marker for pancreatic cancer: A prospective study

scientific article published on 13 May 2018

Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein

scientific article

Stroma-induced Jagged1 expression drives PC3 prostate cancer cell migration; disparate effects of RIP-generated proteolytic fragments on cell behaviour and Notch signaling

scientific article published on 24 February 2016

Structure-activity relationship of hydroxamate-based inhibitors on the secretases that cleave the amyloid precursor protein, angiotensin converting enzyme, CD23, and pro-tumor necrosis factor-alpha

scientific article published on April 2002

Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein

scientific article

The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

scientific article published on 11 October 2014

The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains.

scientific article

The amyloid precursor protein represses expression of acetylcholinesterase in neuronal cell lines

scientific article published on 29 July 2013

The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts

scientific article

The histidine composition of the amyloid-β domain, but not the E1 copper binding domain, modulates β-secretase processing of amyloid-β protein precursor in Alzheimer's disease

scientific article published on January 2015

The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

scientific article published on June 2004

Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).

scientific article published on 27 June 2005

Zinc metalloproteinases and amyloid Beta-Peptide metabolism: the positive side of proteolysis in Alzheimer's disease

scientific article published on 30 September 2010

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