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List of works by Jason M. Mackenzie

2017 international meeting of the Global Virus Network

scientific article published on 5 February 2018

A conserved peptide in West Nile virus NS4A protein contributes to proteolytic processing and is essential for replication

scientific article

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

scientific article

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

scientific article published on 08 June 2021

ATF6 signaling is required for efficient West Nile virus replication by promoting cell survival and inhibition of innate immune responses

scientific article published on 5 December 2012

Adenovirus vector produced Zika virus-like particles induce a long-lived neutralising antibody response in mice

scientific article published in 2023

Antiviral Candidates for Treating Hepatitis E Virus Infection

scientific article published on 24 May 2019

Assembly and Maturation of the Flavivirus Kunjin Virus Appear To Occur in the Rough Endoplasmic Reticulum and along the Secretory Pathway, Respectively

scientific article

Cholesterol manipulation by West Nile virus perturbs the cellular immune response

scientific article published on October 2007

Comparison of the replication properties of murine and human calicivirus RNA-dependent RNA polymerases.

scientific article published on 20 October 2010

Comparisons of physical separation methods of Kunjin virus-induced membranes

scientific article published on September 2004

Conserved amino acids within the N-terminus of the West Nile virus NS4A protein contribute to virus replication, protein stability and membrane proliferation

scientific article

Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5

scientific article

Determinants of Zika virus host tropism uncovered by deep mutational scanning

scientific article published on 18 March 2019

Differential requirements for COPI coats in formation of replication complexes among three genera of Picornaviridae

scientific article published on November 2002

Differential utilisation of ceramide during replication of the flaviviruses West Nile and dengue virus

scientific article published on 26 June 2015

Downregulation of MHC Class I Expression by Influenza A and B Viruses

scientific article published on 29 May 2019

Expression of the hepatitis C virus structural proteins in mammalian cells induces morphology similar to that in natural infection.

scientific article published on January 2002

Flaviviral regulation of the unfolded protein response: can stress be beneficial?

article

Hepatitis C virus p7 protein is localized in the endoplasmic reticulum when it is encoded by a replication-competent genome

scientific article published on January 2007

Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication

scientific article (publication date: June 1996)

Improved membrane preservation of flavivirus-infected cells with cryosectioning.

scientific article published on January 1996

Inducible system in human hepatoma cell lines for hepatitis C virus production

scientific article published in November 2002

Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum

scientific article published on September 2006

Kunjin RNA replication and applications of Kunjin replicons

scientific article published on January 2003

Kunjin Virus Replicon Vectors for Human Immunodeficiency Virus Vaccine Development

scientific article (publication date: July 2003)

Modulation of acyl-carnitines, the broad mechanism behind Wolbachia-mediated inhibition of medically important flaviviruses in Aedes aegypti

scientific article published on 10 September 2020

Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2.

scientific article

Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis

scientific article published on 18 June 2019

Mouse Norovirus infection promotes autophagy induction to facilitate replication but prevents final autophagosome maturation

scientific article published on 25 February 2016

Mouse Norovirus infection reduces the surface expression of MHC class I proteins and inhibits CD8+ T cell recognition and activation

scholarly article by Svenja Fritzlar published in July 2018

Mouse norovirus 1 utilizes the cytoskeleton network to establish localization of the replication complex proximal to the microtubule organizing center

scientific article published in February 2012

Mouse norovirus replication is associated with virus-induced vesicle clusters originating from membranes derived from the secretory pathway

scientific article published on 08 July 2009

Nascent flavivirus RNA colocalized in situ with double-stranded RNA in stable replication complexes

scientific article published on May 1999

Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis

scientific article

Nonnucleoside inhibitors of norovirus RNA polymerase: scaffolds for rational drug design

scientific article

Norovirus Infection: Replication, Manipulation of Host, and Interaction with the Host Immune Response

scientific article published on 27 January 2016

Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection.

scientific article

Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus.

scientific article

Proteins C and NS4B of the flavivirus Kunjin translocate independently into the nucleus

scientific article published on July 1997

RNA Sequencing of Murine Norovirus-Infected Cells Reveals Transcriptional Alteration of Genes Important to Viral Recognition and Antigen Presentation

scientific article

Recent advances in dengue pathogenesis and clinical management

scientific article published on 09 October 2015

Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A Protein

scientific article

Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages

scientific article

Role of Nonstructural Protein NS2A in Flavivirus Assembly

scientific article

Shaping the flavivirus replication complex: It is curvaceous!

scientific article published on 29 June 2018

Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A.

scientific article published on June 1998

Subcellular localization of the MNV-1 ORF1 proteins and their potential roles in the formation of the MNV-1 replication complex

scientific article published on 01 August 2010

Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors.

scientific article

The Adenosine Analogue NITD008 has Potent Antiviral Activity against Human and Animal Caliciviruses

scientific article published on 30 May 2019

The Host Protein Reticulon 3.1A Is Utilized by Flaviviruses to Facilitate Membrane Remodelling

scientific article published in November 2017

The IMPORTance of the Nucleus during Flavivirus Replication

scientific article

The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages

scientific article published on 10 January 2019

The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication

scientific article

The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles

scientific article published on November 2006

The West Nile virus assembly process evades the conserved antiviral mechanism of the interferon-induced MxA protein

scientific article published on 22 October 2013

The dengue virus M protein localises to the endoplasmic reticulum and forms oligomers

scientific article published on 8 March 2012

The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex

scientific article

Vectorial entry and release of hepatitis A virus in polarized human hepatocytes

scientific article published on 25 June 2008

West Nile virus core protein; tetramer structure and ribbon formation.

scientific article

West Nile virus differentially modulates the unfolded protein response to facilitate replication and immune evasion

scientific article published on 29 December 2010

West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles.

scientific article published on 10 June 2019

West Nile virus strain Kunjin NS5 polymerase is a phosphoprotein localized at the cytoplasmic site of viral RNA synthesis

scientific article published in April 2007

West Nile virus-induced cytoplasmic membrane structures provide partial protection against the interferon-induced antiviral MxA protein

scientific article published on November 2007

Wrapping things up about virus RNA replication

scientific article

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