List of works - Claire M Edwards

A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease.

scientific article

Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma

scientific article published on 26 June 2018

Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.

scientific article published on 22 February 2007

Animal Models of Multiple Myeloma

scientific article published on 01 January 2019

Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase

scientific article published on 5 April 2007

Apomine™, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo

scientific article published on 01 April 2007

BTK inhibition in myeloma: targeting the seed and the soil.

scientific article

Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone

scientific article

Bone marrow adiposity and multiple myeloma.

scientific article published on 13 March 2018

Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.

scientific article published on 28 February 2012

Contributions of the Bone Microenvironment to Monoclonal Gammopathy of Undetermined Significance Pathogenesis

scientific article published on 01 December 2018

Contributions of the host microenvironment to cancer-induced bone disease.

scientific article published on 05 March 2014

Diet-induced obesity promotes a myeloma-like condition in vivo

scientific article published on 07 October 2014

LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis

scientific article published on 01 May 2006

Metformin and Prostate Cancer: a New Role for an Old Drug.

scientific article published on June 2017

Modeling the Human Bone-Tumor Niche: Reducing and Replacing the Need for Animal Data

scientific article published on 23 March 2020

Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment

scientific article published on 02 October 2019

Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha

scientific article published on 30 December 2019

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.

scientific article published on May 2009

New approaches to targeting the bone marrow microenvironment in multiple myeloma

scientific article published on 23 March 2016

Novel therapeutic targets in myeloma bone disease

scientific article

Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells ⬇️

scientific article published on November 16, 2012

Preclinical animal models of multiple myeloma

scientific article published on 3 February 2016

Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.

scientific article published on 7 December 2007

Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp)

scientific article published on 26 August 2019

The Role of the Microenvironment in Prostate Cancer-Associated Bone Disease

scientific article

The pathogenesis of the bone disease of multiple myeloma.

scientific article published on 21 February 2008

The role of bone marrow adipocytes in bone metastasis

scientific article published on 08 April 2016

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

scientific article published on 04 October 2019

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer.

scientific article published on 22 December 2016

List of works by Claire M Edwards

A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease.

Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma

Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.

Animal Models of Multiple Myeloma

Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Apomine™, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo

BTK inhibition in myeloma: targeting the seed and the soil.

Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone

Bone marrow adiposity and multiple myeloma.

Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.

Contributions of the Bone Microenvironment to Monoclonal Gammopathy of Undetermined Significance Pathogenesis

Contributions of the host microenvironment to cancer-induced bone disease.

Diet-induced obesity promotes a myeloma-like condition in vivo

LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis

Metformin and Prostate Cancer: a New Role for an Old Drug.

Modeling the Human Bone-Tumor Niche: Reducing and Replacing the Need for Animal Data

Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment

Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.

New approaches to targeting the bone marrow microenvironment in multiple myeloma

Novel therapeutic targets in myeloma bone disease

Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells ⬇️

Preclinical animal models of multiple myeloma

Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.

Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp)

The Role of the Microenvironment in Prostate Cancer-Associated Bone Disease

The pathogenesis of the bone disease of multiple myeloma.

The role of bone marrow adipocytes in bone metastasis

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer.